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Research Output 1981 2019

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2002

Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished

van Beusechem, V. W., Grill, J., Mastenbroek, D. C. J., Wickham, T. J., Roelvink, P. W., Haisma, H. J., Lamfers, M. L. M., Dirven, C. M. F., Pinedo, H. M. & Gerritsen, W. R., Mar 2002, In : Journal of Virology. 76, 6, p. 2753-62 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma

Witlox, M. A., Van Beusechem, V. W., Grill, J., Haisma, H. J., Schaap, G. R., Bras, J., Van Diest, P., De Gast, A., Curiel, D. T., Pinedo, H. M., Gerritsen, W. R. & Wuisman, P. I. J. M., 11 Sep 2002, In : The Journal of Gene Medicine. 4, 5, p. 510-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Gemcitabine-radiotherapy in patients with locally advanced pancreatic cancer

de Lange, S. M., van Groeningen, C. J., Meijer, O. W. M., Cuesta, M. A., Langendijk, J. A., van Riel, J. M. G. H., Pinedo, H. M., Peters, G. J., Meijer, S., Slotman, B. J. & Giaccone, G., Jun 2002, In : European Journal of Cancer. 38, 9, p. 1212-7 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Gene therapy for meningioma: improved gene delivery with targeted adenoviruses

Dirven, C. M. F., Grill, J., Lamfers, M. L. M., Van der Valk, P., Leonhart, A. M., Van Beusechem, V. W., Haisma, H. J., Pinedo, H. M., Curiel, D. T., Vandertop, W. P. & Gerritsen, W. R., Aug 2002, In : Journal of Neurosurgery. 97, 2, p. 441-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach

Gille, J. J. P., Hogervorst, F. B. L., Pals, G., Wijnen, J. T., van Schooten, R. J., Dommering, C. J., Meijer, G. A., Craanen, M. E., Nederlof, P. M., de Jong, D., McElgunn, C. J., Schouten, J. P. & Menko, F. H., 7 Oct 2002, In : British Journal of Cancer. 87, 8, p. 892-7 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Homing and clonogenic outgrowth of CD34+ peripheral blood stem cells: A role for L-selectin?

De Boer, F., Kessler, F. L., Netelenbos, T., Zweegman, S., Huijgens, P. C., Van der Wall, E., Van der Linden, J. A. M., Pinedo, H. M., Schuurhuis, G. J. & Dräger, A. M., 2002, In : Experimental Hematology. 30, 6, p. 590-597 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Human autonomic activity and its response to acute oxygen supplement after high altitude acclimatization

Bao, X., Kennedy, B. P., Hopkins, S. R., Bogaard, H. J., Wagner, P. D. & Ziegler, M. G., 29 Nov 2002, In : Autonomic neuroscience : basic & clinical. 102, 1-2, p. 54-9 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hypoglykemie bij orale bloedglucoseverlagende middelen: Kans op recidief na herstel van de glucosespiegel

Van Vonderen, M. G. A. & Thijs, A., 16 Feb 2002, In : Nederlands Tijdschrift voor Geneeskunde. 146, 7, p. 289-292 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increased resistance to activated protein C after short-term oral hormone replacement therapy in healthy post-menopausal women

Post, M. S., Rosing, J., Van der Mooren, M. J., Zweegman, S., Van Baal, W. M., Kenemans, P. & Stehouwer, C. D. A., 2002, In : British Journal of Haematology. 119, 4, p. 1017-1023 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS

Van Dam, E. W. C. M., Roelfsema, F., Veldhuis, J. D., Helmerhorst, F. M., Frölich, M., Edo Meinders, A., Krans, H. M. J. & Pijl, H., 29 Jun 2002, In : American Journal of Physiology - Endocrinology and Metabolism. 282, 4 45-4

Research output: Contribution to journalArticleAcademicpeer-review

Intercurrent clinical events are predictive of plasma C-reactive protein levels in hemodialysis patients

van Tellingen, A., Grooteman, M. P. C., Schoorl, M., Bartels, P. C. M., Schoorl, M., van der Ploeg, T., ter Wee, P. M. & Nubé, M. J., Aug 2002, In : Kidney International. 62, 2, p. 632-8 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interobserver agreement on captopril renography for assessing renal vascular disease

Krijnen, P., Oei, H. Y., Claessens, R. A. M. J., Roos, J. C., Van Jaarsveld, B. C. & Habbema, J. D. F., 20 Mar 2002, In : Journal of Nuclear Medicine. 43, 3, p. 330-337 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipopolysaccharide concentrations during superflux dialysis using unfiltered bicarbonate dialysate

Van Tellingen, A., Grooteman, M. P. C., Pronk, R., Van Loon, J., Vervloet, M. G., Ter Wee, P. M. & Nubé, M. J., 1 Jan 2002, In : ASAIO Journal. 48, 4, p. 383-388 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Localisation of C reactive protein in infarcted tissue sites of multiple organs during sepsis

Baidoshvili, A., Nijmeijer, R., Lagrand, W. K., Hack, C. E. & Niessen, H. W. M., Feb 2002, In : Journal of Clinical Pathology. 55, 2, p. 152-3 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Low amplitude and disorderly spontaneous growth hormone release in obese women with or without polycystic ovary syndrome

Van Dam, E. W. C. M., Roelfsema, F., Helmerhorst, F. H., Frölich, M., Edo Meinders, A., Veldhuis, J. D. & Pijl, H., 1 Sep 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 9, p. 4225-4230 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Mitotic index does not predict prognosis in stage IA non-small cell lung cancer

Daniels, J. M. A., Eerenberg, J-P., Rijna, H., Kummer, J. A., Broeckaert, M. A. M., Paul, M. A., van Diest, P. J. & van Mourik, J. C., Nov 2002, In : Lung Cancer. 38, 2, p. 163-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Monocyte activation in peripheral blood and dialyser eluates: phenotypic profile and cytokine release

Schouten, W. E. M., Grooteman, M. P. C., Schoorl, M., van Houte, A. J. & Nubé, M. J., Aug 2002, In : Nephron. 91, 4, p. 646-53 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiple fibroadenomas harbouring carcinoma in situ in a woman with a family history of breast/ovarian cancer

Kuijper, A., Preisler-Adams, S. S., Rahusen, F. D., Gille, J. J. P., van der Wall, E. & van Diest, P. J., Oct 2002, In : Journal of Clinical Pathology. 55, 10, p. 795-7 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis

Mauritz, R., Peters, G. J., Priest, D. G., Assaraf, Y. G., Drori, S., Kathmann, I., Noordhuis, P., Bunni, M. A., Rosowsky, A., Schornagel, J. H., Pinedo, H. M. & Jansen, G., 15 Jan 2002, In : Biochemical Pharmacology. 63, 2, p. 105-15 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34+ precursors

Masterson, A. J., Sombroek, C. C., De Gruijl, T. D., Graus, Y. M. F., van der Vliet, H. J. J., Lougheed, S. M., van den Eertwegh, A. J. M., Pinedo, H. M. & Scheper, R. J., 15 Jul 2002, In : Blood. 100, 2, p. 701-3 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Organizing and activating effects of sex hormones in homosexual transsexuals

Van Goozen, S. H. M., Slabbekoorn, D., Gooren, L. J. G., Sanders, G. & Cohen-Kettenis, P. T., 1 Jan 2002, In : Behavioral Neuroscience. 116, 6, p. 982-988 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Penile lesions and human papillomavirus in male sexual partners of women with cervical intraepithelial neoplasia

Bleeker, M. C. G., Hogewoning, C. J. A., Van Den Brule, A. J. C., Voorhorst, F. J., Van Andel, R. E., Risse, E. K. J., Starink, T. M. & Meijer, C. J. L. M., Sep 2002, In : Journal of the American Academy of Dermatology. 47, 3, p. 351-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy

Lamfers, M. L. M., Grill, J., Dirven, C. M. F., Van Beusechem, V. W., Geoerger, B., Van Den Berg, J., Alemany, R., Fueyo, J., Curiel, D. T., Vassal, G., Pinedo, H. M., Vandertop, W. P. & Gerritsen, W. R., 15 Oct 2002, In : Cancer Research. 62, 20, p. 5736-42 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Potential of the conditionally replicative adenovirus Ad5-Δ24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy

Lamfers, M. L. M., Grill, J., Dirven, C. M. F., Van Beusechem, V. W., Geoerger, B., Van Den Berg, J., Alemany, R., Fueyo, J., Curiel, D. T., Vassal, G., Pinedo, H. M., Vandertop, W. P. & Gerritsen, W. R., 15 Oct 2002, In : Cancer Research. 62, 20, p. 5736-5742 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Proteoglycans guide SDF-1-induced migration of hematopoietic progenitor cells

Netelenbos, T., Zuijderduijn, S., van den Born, J., Kessler, F. L., Zweegman, S., Huijgens, P. C. & Drager, A. M., 2002, In : J. Leukoc. Biol.. 72, 2, p. 353-362 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radiation therapy in early stage Hodgkin's disease: long-term results and adverse effects

Zijlstra, J. M., Dressel, A. J. N., Mens, J. W., Tinteren, H. V., Slotman, B. J., Jonkhoff, A. R. & Huijgens, P. C., 2002, In : Haematologica. 3, 4, p. 179-84 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ranking of allergenic potency of rubber chemicals in a modified local lymph node assay

De Jong, WH., Van Och, FMM., Jager, CFD., Spiekstra, SW., Slob, W., Vandebriel, RJ. & Van Loveren, H., Apr 2002, In : Toxicological Sciences. 66, 2, p. 226-232

Research output: Contribution to journalArticleAcademicpeer-review

Reproducibility and clinical value of F-fluorodeoxyglucose positron emission tomography in recurrent melanoma

Mijnhout, G. S., Comans, E. F. I., Raijmakers, P., Hoekstra, O. S., Teule, G. J. J., Boers, M., De Gast, G. C. & Adèr, H. J., 1 Jan 2002, In : Nuclear Medicine Communications. 23, 5, p. 475-481 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reproducibility of gait analysis variables: one-step versus three-step method of data acquisition

Peters, E. J. G., Urukalo, A., Fleischli, J. G. & Lavery, L. A., 27 Aug 2002, In : Journal of Foot and Ankle Surgery. 41, 4, p. 206-12 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines

Rothem, L., Ifergan, I., Kaufman, Y., Priest, D. G., Jansen, G. & Assaraf, Y. G., 1 Nov 2002, In : Biochemical Journal. 367, Pt 3, p. 741-50 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Role of the autonomic nervous system in the reduced maximal cardiac output at altitude

Bogaard, H. J., Hopkins, S. R., Yamaya, Y., Niizeki, K., Ziegler, M. G. & Wagner, P. D., Jul 2002, In : Journal of Applied Physiology. 93, 1, p. 271-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Screening for Type 2 diabetes: An exploration of subjects' perceptions regarding diagnosis and procedure

Adriaanse, M. C., Snoek, F. J., Dekker, J. M., Van Der Ploeg, H. M. & Heine, R. J., 30 May 2002, In : Diabetic Medicine. 19, 5, p. 406-411 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Secreted and tumour targeted human carboxylesterase for activation of irinotecan

Oosterhoff, D., Pinedo, H. M., van der Meulen, I. H., de Graaf, M., Sone, T., Kruyt, F. A., van Beusechem, V. W., Haisma, H. J. & Gerritsen, W. R., 9 Sep 2002, In : British Journal of Cancer. 87, 6, p. 659-64 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Secretory type II phospholipase A(2) binds to ischemic myocardium during myocardial infarction in humans

Nijmeijer, R., Lagrand, W. K., Baidoshvili, A., Lubbers, Y. T. P., Hermens, W. T., Meijer, C. J. L. M., Visser, C. A., Hack, C. E. & Niessen, H. W. M., Jan 2002, In : Cardiovascular Research. 53, 1, p. 138-46 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection

van der Vliet, H. J. J., von Blomberg, B. M. E., Hazenberg, M. D., Nishi, N., Otto, S. A., van Benthem, B. H., Prins, M., Claessen, F. A., van den Eertwegh, A. J. M., Giaccone, G., Miedema, F., Scheper, R. J. & Pinedo, H. M., 1 Feb 2002, In : Journal of Immunology. 168, 3, p. 1490-5 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Selective gene transfer into primary human gastric tumors using epithelial cell adhesion molecule-targeted adenoviral vectors with ablated native tropism

Heideman, D. A. M., van Beusechem, V. W., Offerhaus, G. J. A., Wickham, T. J., Roelvink, P. W., Craanen, M. E., Pinedo, H. M., Meijer, C. J. L. M. & Gerritsen, W. R., 20 Sep 2002, In : Human Gene Therapy. 13, 14, p. 1677-85 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The association between birth weight and capillary recruitment is independent of blood pressure and insulin sensitivity: A study in prepubertal children

IJzerman, R. G., Van Weissenbruch, M. M., Voordouw, J. J., Yudkin, J. S., Serne, E. H., Delemarre-van de Waal, H. A. & Stehouwer, C. D. A., 1 Oct 2002, In : Journal of Hypertension. 20, 10, p. 1957-1963 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The association between low birth weight and high levels of cholesterol is not due to an increased cholesterol synthesis or absorption: analysis in twins.

Ijzerman, R. G., Stehouwer, C. D. A., de Geus, E. J., van Weissenbruch, M. M., Delemarre-van de Waal, H. A. & Boomsma, D. I., 1 Dec 2002, In : Pediatric Research. 52, 6, p. 868-872 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The harry benjamin international gender dysphoria association’s standards of care for gender identity disorders, sixth version

Meyer, W., Bockting, W. O., Cohen-Kettenis, P., Coleman, E., Diceglie, D., Devor, H., Gooren, L., Hage, J. J., Kirk, S., Kuiper, B., Laub, D., Lawrence, A., Menard, Y., Patton, J., Schaefer, L., Webb, A. & Wheeler, C. C., 11 Apr 2002, In : Journal of Psychology and Human Sexuality. 13, 1, p. 1-30 30 p.

Research output: Contribution to journalArticleAcademicpeer-review

The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro

Grill, J., Lamfers, M. L. M., van Beusechem, V. W., Dirven, C. M., Pherai, D. S., Kater, M., Van der Valk, P., Vogels, R., Vandertop, W. P., Pinedo, H. M., Curiel, D. T. & Gerritsen, W. R., Nov 2002, In : Molecular Therapy. 6, 5, p. 609-14 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells

Kuzmin, I., Gillespie, J. W., Protopopov, A., Geil, L., Dreijerink, K., Yang, Y., Vocke, C. D., Duh, F. M., Zabarovsky, E., Minna, J. D., Rhim, J. S., Emmert-Buck, M. R., Linehan, W. M. & Lerman, M. I., 15 Jun 2002, In : Cancer Research. 62, 12, p. 3498-3502 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of haemangiopericytoma-associated hypoglycaemia with embolisation

Nanayakkara, P. W. B., Van Doorn, J., Van den Berg, F. G., Van Groeningen, C. J., Pinedo, H. M. & Hoekman, K., 1 Jan 2002, In : European Journal of Internal Medicine. 13, 5, p. 340-343 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of myeloma: Recent developments

Zweegman, S. & Huijgens, P. C., 2002, In : Anti-Cancer Drugs. 13, 4, p. 339-351 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Validity of pulse oximetry during maximal exercise in normoxia, hypoxia, and hyperoxia

Yamaya, Y., Bogaard, H. J., Wagner, P. D., Niizeki, K. & Hopkins, S. R., Jan 2002, In : Journal of Applied Physiology. 92, 1, p. 162-8 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001

Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma

Heideman, D. A., Snijders, P. J., Bloemena, E., Meijer, C. J., Offerhaus, G. J., Meuwissen, S. G., Gerritsen, W. R. & Craanen, M. E., Aug 2001, In : Journal of Pathology. 194, 4, p. 428-35 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia

Rots, M. G., Pieters, R., Jansen, G., Kaspers, G. J., Van Zantwijk, C. H., Noordhuis, P., Voorn, D. A., Van Wering, E. R., Creutzig, U., Veerman, A. J. & Peters, G. J., Mar 2001, In : European Journal of Cancer. 37, 4, p. 492-8 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions

Serné, E. H., Gans, R. O. B., Ter Maaten, J. C., Ter Wee, P. M., Donker, A. J. M. & Stehouwer, C. D. A., 1 Jan 2001, In : Cardiovascular Research. 49, 1, p. 161-168 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

van der Vliet, H. J., von Blomberg, B. M., Nishi, N., Reijm, M., Voskuyl, A. E., van Bodegraven, A. A., Polman, C. H., Rustemeyer, T., Lips, P., van den Eertwegh, A. J., Giaccone, G., Scheper, R. J. & Pinedo, H. M., Aug 2001, In : Clinical Immunology. 100, 2, p. 144-8 5 p.

Research output: Contribution to journalArticleAcademicpeer-review