01 Internal and external specialisms

Research Output 1981 2019

Filter
Article
1993

Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck

Braakhuis, B. J., Jansen, G. & Peters, G. J., 1993, In : Advances in Experimental Medicine and Biology. 338, p. 671-4 4 p.

Research output: Contribution to journalArticleAcademic

1992

Acute abdominal haemorrhage due to cholesterol crystal embolisation

Bartelink, A. K. M., Van Jaarsveld, B. C., Meyer, A. M. & Cluysenaer, O. J. J., 1 Jan 1992, In : Clinical Intensive Care. 3, 3, p. 134-136 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate

van der Laan, B. F., Jansen, G., Kathmann, G. A., Westerhof, G. R., Schornagel, J. H. & Hordijk, G. J., 30 Jul 1992, In : International Journal of Cancer. 51, 6, p. 909-14 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Measurement of folylpolyglutamate synthetase activity in head and neck squamous carcinoma cell lines and clinical samples using a new rapid separation procedure

Jansen, G., Schornagel, J. H., Kathmann, I., Westerhof, G. R., Hordijk, G. J. & van der Laan, B. F., 1992, In : Oncology Reports. 4, 7, p. 299-305 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Molecular events in the membrane transport of methotrexate in human CCRF-CEM leukemia cell lines

Freisheim, J. H., Ratnam, M., McAlinden, T. P., Prasad, K. M., Williams, F. E., Westerhof, G. R., Schornagel, J. H. & Jansen, G., 1992, In : Advances in enzyme regulation. 32, p. 17-31 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Performance characteristics of a 511-keV collimator for imaging positron emitters with a standard gamma-camera

Van Lingen, A., Huijgens, P. C., Visser, F. C., Ossenkoppele, G. J., Hoekstra, O. S., Martens, H. J. M., Huitink, H., Herscheid, K. D. M., Greens, M. V. & Teule, G. J. J., 1 May 1992, In : European Journal of Nuclear Medicine. 19, 5, p. 315-321 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The relation between periodontitis and systemic bone mass in women between 46 and 55 years of age

Elders, P. J. M., Habets, L. L. M. H., Netelenbos, J. C., van der Linden, L. W. J. & van der Sieit, P. F., 1992, In : Journal of Clinical Periodontology. 19, 7, p. 492-496

Research output: Contribution to journalArticleAcademicpeer-review

1991

A prospective, randomized study comparing the peritonitis incidence of CAPD and Y-connector (CAPD-Y) with continuous cyclic peritoneal dialysis (CCPD).

de Fijter, C. W., Oe, P. L., Nauta, J. J., van der Meulen, J., ter Wee, P. M., Snoek, F. J. & Donker, A. J., 1 Jan 1991, In : Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. 7, p. 186-189 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Calcium supplementation reduces vertebral bone loss in perimenopausal women: A controlled trial in 248 women between 46 and 55 years of age

Elders, P. J. M., Netelenbos, J. C., Lips, P., Ginkel, F. C. V., Khoe, E., Leeuwenkamp, O. R., Hackeng, W. H. L. & Stelt, P. F. V. D., 1991, In : Journal of Clinical Endocrinology and Metabolism. 73, 3, p. 533-540

Research output: Contribution to journalArticleAcademicpeer-review

Growth-inhibitory effects of 5,10-dideazatetrahydrofolic acid on variant murine L1210 and human CCRF-CEM leukemia cells with different membrane-transport characteristics for (anti)folate compounds

Jansen, G., Westerhof, G. R., Kathmann, I., Rijksen, G. & Schornagel, J. H., 1991, In : Cancer Chemotherapy and Pharmacology. 28, 2, p. 115-7 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mechanisms of acquired resistance to methotrexate in a human squamous carcinoma cell line of the head and neck, exposed to different treatment schedules

van der Laan, B. F., Jansen, G., Kathmann, I., Schornagel, J. H. & Hordijk, G. J., 1991, In : European Journal of Cancer. 27, 10, p. 1274-8 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Membrane transport of methotrexate in a squamous carcinoma cell line adapted to low folate concentrations

van der Laan, B. F., Jansen, G., van Gestel, J. A., Schornagel, J. H. & Hordijk, G. J., 1 May 1991, In : Anticancer Research. 11, 3, p. 1265-8 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems

Westerhof, G. R., Jansen, G., van Emmerik, N., Kathmann, I., Rijksen, G., Jackman, A. L. & Schornagel, J. H., 15 Oct 1991, In : Cancer Research. 51, 20, p. 5507-13 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of congenital heart disease in patients with phenylketonuria

Verkerk, P. H., van Spronsen, F. J., Smit, G. P. A., Cornel, M. C., Kuipers, J. R. G. & Verloove-Vanhorick, S. P., 1 Jan 1991, In : The Journal of Pediatrics. 119, 2, p. 282-283 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Synthesis and biological evaluation of a fluorescent analogue of folic acid

McAlinden, T. P., Hynes, J. B., Patil, S. A., Westerhof, G. R., Jansen, G., Schornagel, J. H., Kerwar, S. S. & Freisheim, J. H., 11 Jun 1991, In : Biochemistry. 30, 23, p. 5674-81 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effect of 6 weeks of testosterone treatment on pulsatile luteinizing hormone secretion in eugonadal female-to-male transsexuals

Scheele, F., Hompes, P. G. A., Gooren, L. J. G., Spijkstra, J. J. & Spinder, T., 1 Jan 1991, In : Fertility and Sterility. 55, 3, p. 608-611 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

1990

An alcoholic with pleural effusion

Girbes, A. R. J., Postmus, P. E., Jansen, W., Jagt, V. D. E. J. & Kleibeuker, J. H., 1 Dec 1990, In : European Respiratory Journal. 3, 8, p. 934-936 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

A new method for automatic recognition of the radiographic trabecular pattern

Geraets, W. G. M., van der Stelt, P. F., Netelenbos, C. J. & Elders, P. J. M., 1990, In : Journal of Bone and Mineral Research. 5, 3, p. 227-233

Research output: Contribution to journalArticleAcademicpeer-review

Hydrops fetalis associated with red cell pyruvate kinase deficiency

Hennekam, R. C., Beemer, F. A., Cats, B. P., Jansen, G. & Staal, G. E., 1990, In : Genetic Counseling. 1, 1, p. 75-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Massive pleural effusion due to pancreatic pseudocyst

Girbes, A. R. J., Postmus, P. E., Jansen, W., Jagt, V. D. E. J. & Kleibeuker, J. H., 1 Jan 1990, In : Thorax. 45, 7, p. 563-564 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates

Jansen, G., Westerhof, G. R., Jarmuszewski, M. J., Kathmann, I., Rijksen, G. & Schornagel, J. H., 25 Oct 1990, In : Journal of Biological Chemistry. 265, 30, p. 18272-7 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors

Jansen, G., Schornagel, J. H., Westerhof, G. R., Rijksen, G., Newell, D. R. & Jackman, A. L., 1 Dec 1990, In : Cancer Research. 50, 23, p. 7544-8 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

1989

Cytotoxicity of methotrexate and trimetrexate and its reversal by folinic acid in human leukemic CCRF-CEM cells with carrier-mediated and receptor-mediated folate uptake

van der Veer, L. J., Westerhof, G. R., Rijksen, G., Schornagel, J. H. & Jansen, G., 1989, In : Leukemia Research. 13, 11, p. 981-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of the pure antiandrogen RU 23.903 (anandron) on sexuality, aggression, and mood in male-to-female transsexuals

van Kemenade, J. F. L. M., Cohen-Kettenis, P. T., Cohen, L. & Gooren, L. J. G., 1 Jun 1989, In : Archives of Sexual Behavior. 18, 3, p. 217-228 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression of a folate binding protein in L1210 cells grown in low folate medium

Jansen, G., Kathmann, I., Rademaker, B. C., Braakhuis, B. J., Westerhof, G. R., Rijksen, G. & Schornagel, J. H., 15 Apr 1989, In : Cancer Research. 49, 8, p. 1959-63 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance

Jansen, G., Westerhof, G. R., Kathmann, I., Rademaker, B. C., Rijksen, G. & Schornagel, J. H., 1 May 1989, In : Cancer Research. 49, 9, p. 2455-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interaction of N-hydroxy(sulfo) succinimide active esters with the reduced folate/methotrexate transport system from human leukemic CCRF-CEM cells

Jansen, G., Westerhof, G. R., Rijksen, G. & Schornagel, J. H., 3 Nov 1989, In : Biochimica et Biophysica Acta. Reviews on Cancer. 985, 3, p. 266-70 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Perimenopausal bone mass and risk factors

Elders, P. J. M., Netelenbos, J. C., Lips, P., Khoe, E., van Ginkel, F. C., Hulshof, K. F. A. M. & van der Stelt, P. F., 1989, In : Bone and Mineral. 7, 3, p. 289-299

Research output: Contribution to journalArticleAcademicpeer-review

Pulsatile luteinizing hormone release and ovarian steroid levels in female-to-male transsexuals compared to heterosexual women

Spinder, T., Spijkstra, J. J., Gooren, L. J. G. & Burger, C. W., 1 Jan 1989, In : Psychoneuroendocrinology. 14, 1-2, p. 97-102 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effects of long term testosterone administration on pulsatile luteinizing hormone secretion and on ovarian histology in eugonadal female to male transsexual subjects

Spinder, T., Spijkstra, J. J., Van Den Tweel, J. G., Burger, C. W., Van Kessel, H., Hompes, P. G. A. & Gooren, L. J. G., 1 Jan 1989, In : Journal of Clinical Endocrinology and Metabolism. 69, 1, p. 151-157 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1988

Chylothorax and chylopericardium

Smeets, R. E. H., Van Jaarsveld, B. C., Gooszen, H. C. & Schipper, R. M., 1 Jan 1988, In : Nederlands Tijdschrift voor Geneeskunde. 132, 34, p. 1584-1587 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

EFFECTS OF OPIATE RECEPTOR BLOCKADE ON GONADOTROPHIN SECRETION BEFORE AND AFTER ADMINISTRATION OF THE OESTROGEN RECEPTOR BLOCKER TAMOXIFEN IN EUGONADAL MEN

SPIJKSTRA, J. J., SPINDER, T., GOOREN, L. J. G. & VAN KESSEL, H., 1 Jan 1988, In : Clinical Endocrinology. 29, 2, p. 179-188 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy and advantages in the use of low doses of anandron and estrogen combination in the treatment of prostate cancer

Rao, B. R., Geldof, A. A., van Der Wilt, C. L. & de Voogt, H. J., 1 Jan 1988, In : The Prostate. 13, 1, p. 69-78 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Erotosexuality in a man lacking physiological postnatal androgen exposure

Gooren, L. J. G. & Cohen-Kettenis, P., 1 Jan 1988, In : Journal of Psychology and Human Sexuality. 1, 1, p. 129-135 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Merits and considerations in the use of anti-androgen

Rao, B. R., de Voogt, H. J., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1988, In : Journal of Steroid Biochemistry. 31, 4, p. 731-737 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Short-term patterns of pulsatile luteinizing hormone secretion do not differ between male-to-female transsexuals and heterosexual men

Spijkstra, J. J., Spinder, T. & Gooren, L. J. G., 1 Jan 1988, In : Psychoneuroendocrinology. 13, 3, p. 279-283 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

1987

Androgen action blockade does not result in reduction in size but changes histology of the normal human prostate

De Voogt, H. J., Rao, B. R., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1987, In : The Prostate. 11, 4, p. 305-311 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sex steroids and pulsatile luteinizing hormone release in men. studies in estrogen-treated agonadal subjects and eugonadal subjects treated with a novel nonsteroidal antiandrogen

Gooren, L., Spinder, T., Spijkstra, J. J., Van Kessel, H., Smals, A., Rao, B. R. & Hoogslag, M., 1 Jan 1987, In : Journal of Clinical Endocrinology and Metabolism. 64, 4, p. 763-770 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1986

Glycolytic activity in human red cell populations separated by a combination of density and counterflow centrifugation. Evidence for an improved separation of red cells according to age

Jansen, G., Hepkema, B. G., van der Vegt, S. G. & Staal, G. E., Sep 1986, In : Scandinavian journal of haematology. 37, 3, p. 189-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1985

Age dependent behaviour of red cell glycolytic enzymes in haematological disorders

Jansen, G., Koenderman, L., Rijksen, G., Punt, K., Dekker, A. W. & Staal, G. E., Sep 1985, In : British Journal of Haematology. 61, 1, p. 51-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Characteristics of hexokinase, pyruvate kinase, and glucose-6-phosphate dehydrogenase during adult and neonatal reticulocyte maturation

Jansen, G., Koenderman, L., Rijksen, G., Cats, B. P. & Staal, G. E., Nov 1985, In : American Journal of Hematology. 20, 3, p. 203-15 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

1984

Changes in activities and isozyme patterns of glycolytic enzymes during erythroid differentiation in vitro

Nijhof, W., Wierenga, P. K., Staal, G. E. & Jansen, G., Sep 1984, In : Blood. 64, 3, p. 607-13 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Glucose-6-phosphate isomerase deficiency-Nahariya: extreme in vitro and in vivo lability of the mutant enzyme

Rijksen, G., Jansen, G., Manaster, J., Ezekiel, E., Streichman, S. & Staal, G. E., Jun 1984, In : American Journal of the Medical Sciences. 20, 6, p. 529-34 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pyruvate kinase and the "high ATP syndrome"

Staal, G. E., Jansen, G. & Roos, D., Jul 1984, In : Journal of Clinical Investigation. 74, 1, p. 231-5 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

1983

Glycolytic enzymes of an erythroleukemic cell line, K562, before and after hemoglobin induction

Jansen, G., Rijksen, G., de Gast, G. C. & Staal, G. E., Aug 1983, In : Experimental Hematology. 11, 7, p. 626-38 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

1981

Separation and characterization of hexokinase I subtypes from human erythrocytes

Rijksen, G., Jansen, G., Kraaijenhagen, R. J., Van der Vlist, M. J., Vlug, A. M. & Staal, G. E., 15 Jun 1981, In : Biochimica et Biophysica Acta. Reviews on Cancer. 659, 2, p. 292-301 10 p.

Research output: Contribution to journalArticleAcademicpeer-review