09 Laboratory specialisms

Research Output 1979 2020

Filter
Meeting Abstract
2019

Characterization of brainstem TDP-43 distribution in FTD cases with ALS features

Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436

Research output: Contribution to journalMeeting AbstractAcademic

COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA

Macintyre, G., Goranova, T. E., De Silva, D., Ennis, D., Piskorz, A. M., Eldridge, M., Sie, D., Lewsley, L-A., Hanif, A., Wilson, C., Dowson, S., Glasspool, R. M., Lockley, M., Brockbank, E., Montes, A., Walther, A., Sundar, S., Edmondson, R., Hall, G. D., Clamp, A. & 19 othersGourley, C., Hall, M., Fotopoulou, C., Gabra, H., Paul, J., Supernat, A., Millan, D., Hoyle, A., Bryson, G., Nourse, C., Mincarelli, L., Sanchez, L. N., Ylstra, B., Jimenez-Linan, M., Moore, L., Hofmann, O., Markowetz, F., McNeish, I. A. & Brenton, J. D., Nov 2019, In : Clinical Cancer Research. 25, 22, p. 64-64

Research output: Contribution to journalMeeting AbstractAcademic

DEVELOPMENT AND USABILITY OF ADAPPT: AN ONLINE TOOL TO SUPPORT CLINICIANS, PATIENTS AND CAREGIVERS IN THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT AND ALZHEIMER’S DISEASE

Van Maurik, I. S., Visser, L. N. C., Pel-Littel, R., van Buchem, M., Zwan, M. D., Kunneman, M., Pelkmans, W., Bouwman, F. H., Minkman, M., Schoonenboom, N. S. M., Scheltens, P., Smets, E. M. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P163-P164

Research output: Contribution to journalMeeting AbstractAcademic

FEASIBILITY OF A FIRST PEDIATRIC METABOLITE IN SAFETY TESTING PILOT STUDY USING AN ORAL C-14-MIDAZOLAM MICROTRACER.

van Groen, B. D., van Duijn, E., de Vries, A., Mooij, M. G., Windhorst, A. D., Hendrikse, N. H., Tibboel, D., Vaes, W. H. J. & de Wildt, S. N., Mar 2019, In : Clinical Pharmacology & Therapeutics. 105, p. S38-S38

Research output: Contribution to journalMeeting AbstractAcademic

Implementing NIPT as part of a national prenatal screening program: The Dutch TRIDENT studies

Weiss, M. M., Galjaard, R. H., Sistermans, E. A., Bax, C. J., Bekker, M. N., de Die-Smulders, C. E. M., Feenstra, I., Hoffer, M. J. V., den Hollander, N. S., Knapen, M. F. C. M., van Langen, I. M., Lichtenbelt, K. D., Lombardi, P. M., van Maarle, M. C., van der Meij, K. R. M., Pieters, M. J., Schuring-Blom, G. H., Sikkel, E., Stevens, S. J., Suijkerbuijk, R. F. & 4 othersvan der Ven, A. J. E. M., Van Opstal, D., Henneman, L. & Macville, M. V., Jul 2019, In : European Journal of Human Genetics. 27, p. 823-824

Research output: Contribution to journalMeeting AbstractAcademic

Implementing pharmacogenetics by repurposing next generation sequencing data on a personalized card

Santcroos, M. A., Vis, J. K., van der Lee, M., Anvar, S. Y., Kriek, M., Grandia, L., Sie, D. L. S., Cornel, M. C., Bet, P. M. & Swen, J. J., Oct 2019, In : European Journal of Human Genetics. 27, p. 1681-1681

Research output: Contribution to journalMeeting AbstractAcademic

Informing relatives at risk of inherited cardiac conditions: attitudes of healthcare professionals, probands and relatives

Van den Heuvel, L. M., Huisinga, M. J., Hoedemaekers, Y. M., Baas, A. B., Plantinga, M., Henneman, L., van Tintelen, J. P., Smets, E. M. A. & Christiaans, I., Jul 2019, In : European Journal of Human Genetics. 27, p. 674-675

Research output: Contribution to journalMeeting AbstractAcademic

Lesion detection by [Zr-89]Zr-DFO-girentuximab and [F-18] FDG-PET in patients with newly diagnosed metastatic renal cell carcinoma

Verhoeff, S., van Es, S. C., Boon, E., van Helden, E., Angus, L., Elias, S. G., Oosting, S. F., Aarntzen, E. H., Brouwers, A. H., Kwee, T. C., Heskamp, S., Hoekstra, O. S., Verheul, H., Zwezerijnen, G. J. C., van Oordt, C. M. D. H., van der Veldt, A. A. M., de Vries, E. G. E., Boerman, O. C., van der Graaf, W. T. A., Oyen, W. J. G. & 1 othersvan Herpen, C. M. L., Oct 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, SUPPL 1, p. S67-S67

Research output: Contribution to journalMeeting AbstractAcademic

Medical costs of children admitted to the Neonatal Intensive Care Unit; the role and possible value of rapid Whole Exome Sequencing

Keizer, R. A. C. M. O., Deden, A. C., van Zelst-Stams, W. A. G., de Boode, W. P., Henneman, L., van Amstel, J. K. P., Vissers, L. E. L. M. & Frederix, G. W. J., Oct 2019, In : European Journal of Human Genetics. 27, p. 1652-1652

Research output: Contribution to journalMeeting AbstractAcademic

MicroRNA expression profiling predicts clinical outcome in patients with locally advanced larynx and hypopharynx cancer treated with chemoradiotherapy

Poel, D., Rustenburg, F., Sie, D., van Essen, H. F., Eijk, P. P., Bloemena, E., Benites, T. E., Ylstra, B., Ruud, B. H., Leemans, R. C., Buffart, T. E., Verheul, H. M. & Voortman, J., Jul 2019, In : Cancer Research. 79, 13

Research output: Contribution to journalMeeting AbstractAcademic

Next Generation Sequencing in health care and clinical research: attuning all steps

Rigter, T., Belien, J. A. M., de Wert, G. M. W. R., Ploem, C., Bunnik, E. M., Bredenoord, A. L. & Cornel, M. C., Oct 2019, In : European Journal of Human Genetics. 27, p. 1790-1791

Research output: Contribution to journalMeeting AbstractAcademic

P01.05: Low fetal fraction in NIPT: aneuploidy and adverse pregnancy outcome

Wirjosoekarto, S., Scheffer, P., Weiss, J., Bax, C., Bilardo, C. M., Sistermans, E., Henneman, L. & Bekker, M. N., Oct 2019, In : Ultrasound in Obstetrics and Gynecology. 54, S1, p. 156-156 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Pulmonary Hypertension in a Nonreferral Setting in the Netherlands: Incidence and Patient Characteristics in the Optics Registry

Jansen, S., in 't Veld, A. E. H., Tolen, P. C. G., Jacobs, W., Grotjohan, H. P., Waskowsky, W., van der Maten, J., van der Weerdt, A., Hoekstra, R., Overbeek, M., Mollema, S., el Bouazzaoui, L. H. H., Vriend, J., Roorda, M., de Nooijer, R., van der Lee, I., Voogel, A. J., Peels, C., Aerts, J. G., Van de Ven, M. & 3 othersDe Man, F., Noordegraaf, A. V. & Bogaard, H. J., 2019, In : American Journal of Respiratory and Critical Care Medicine. 199

Research output: Contribution to journalMeeting AbstractAcademic

SLCO1B1 c.521T > C genotype, sex, and initial statin treatment as contributing factors to continuous simvastatin or atorvastatin treatment in a Dutch cohort

Jansen, M. E., Rigter, T., Fleur, T. M. C., Souverein, P., Vijverberg, S. J. H., Rodenburg, W. & Cornel, M. C., Jul 2019, In : European Journal of Human Genetics. 27, p. 558-559

Research output: Contribution to journalMeeting AbstractAcademic

THE EFFECT OF HIGH-INTENSITY RESISTANCE TRAINING AND VITAMIN D SUPPLEMENTATION ON MUSCLE STRENGTH IN PATIENTS WITH KNEE OSTEOARTHRITIS: A RANDOMIZED CONTROLLED TRIAL

de Zwart, A., Dekker, J., Roorda, L. D., van der Esch, M., Lips, P., van Schoor, N., Heijboer, A., Turkstra, F., Gerritsen, M., Hakkinen, A., Bennell, K., Steultjens, M., Lems, W. & van der Leeden, M., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 154-155

Research output: Contribution to journalMeeting AbstractAcademic

The ethics of clinical applications of germline genome modification:a systematic review of reasons

van Dijke, I., Bosch, L., Bredenord, A. L., Cornel, M., Repping, S. & Hendriks, S., Jul 2019, In : European Journal of Human Genetics. 27, p. 689-689

Research output: Contribution to journalMeeting AbstractAcademic

2018

Actions, roles, and responsibilities in implementation of pharmacogenomics in primary care

Jansen, M. E., Rigter, T., Janssen, S., Rodenburg, W. & Cornel, M. C., Oct 2018, In : European Journal of Human Genetics. 26, p. 687-688

Research output: Contribution to journalMeeting AbstractAcademic

Association of Chromosomal Instability, Microsatellite Instability and CPG Island Methylator Phenotype with Postcolonoscopy Colorectal Cancer in a Population Based Study

Bogie, R. M. M., le Clercq, C. M. C., Voorham, Q. J. M., Cordes, M., Sie, D., Rausch, C., van den Broek, E., de Vries, S. D. J., van Grieken, N. C. T., Riedl, R. G., Sastrowijoto, P., van Engeland, M., Ylstra, B., Meijer, G. A., Masclee, A. A. M., Carvalho, B. & Sanduleanu, S., Sep 2018, In : Journal of Pathology. 246, p. S31-S31

Research output: Contribution to journalMeeting AbstractAcademic

COLD ATMOSPHERIC PRESSURE PLASMA: A NOVEL TREATMENT MODALITY IN DIABETIC FOOT ULCERS

Boekema, B. K. H. L., Ulrich, M. M. W., Smits, P., Zeper, B., Lagrand, R. S., Peters, E. J. G., Middelkoop, E. & Sabelis, L. W. E., 2018, In : Wound Repair and Regeneration. p. A18-A19 2 p., 26.

Research output: Contribution to journalMeeting AbstractAcademic

Correlation Between Diaphragm Thickening Fraction and Electrical Activity

Dres, M., Madotto, F., Junhasavasdikul, D., Telias, I. G., Grieco, D., Damiani, L. F., Piraino, T., Pham, T., Melo, L., Chen, L., Heunks, L. M., Sinderby, C. A. & Brochard, L. J., 2018, In : American Journal of Respiratory and Critical Care Medicine. 197

Research output: Contribution to journalMeeting AbstractAcademic

Designing a classification system to determine the severity of microphthalmia and anophthalmia

Groot, A. L. W., Kuijten, M. M. P., Gilani, A., Kraal-Biezen, E., de Graaf, P., Zwijnenburg, P., Saeed, P., Moll, A. C. & Hartong, D. T., Mar 2018, In : Acta Ophthalmologica. 96, p. 41-42

Research output: Contribution to journalMeeting AbstractAcademic

Diagnosing frontotemporal dementia: clinico-pathological correlations in the Dutch population

Scarioni, M., Gami-Patel, P., van Swieten, J. C., Rozemuller, A., Dols, A., Hoozemans, J. J., Pijnenburg, Y. A. & Dijkstra, A. A., Jun 2018, In : European Journal of Neurology. 25, p. 478-478

Research output: Contribution to journalMeeting AbstractAcademic

Elucidating the Role of the Lymphatic System in the Pathogenesis of Psoriasis and Psoriatic Arthritis

den Braanker, H., Otten-Mus, A., Asmawidjaja, P., Davelaar, N., de Smet, A. A. E. A., Akkersdijk, G. P., Fioole, B., Jaquet, J. B., Hofman, A., Schuitema, O. P., Tas, S. W., Mebius, R., Lubberts, E., Kok, M. R. & Bisoendial, R. J., Sep 2018, In : Arthritis & rheumatology. 70

Research output: Contribution to journalMeeting AbstractAcademic

Evaluation of an expanded carrier screening offer in a non commercial setting

Lakeman, P., van Koningsbruggen, S., Redeker, E. J. W., Ottenheim, C. P. E., Mathijssen, I. B., Cornel, M. C., Mannens, M. M. A. M., Meijers-Heijboer, E. J. & Henneman, L., Oct 2018, In : European Journal of Human Genetics. 26, p. 82-83

Research output: Contribution to journalMeeting AbstractAcademic

Gene editing, NIPT

Cornel, M. C., Oct 2018, In : European Journal of Human Genetics. 26, p. 29-30

Research output: Contribution to journalMeeting AbstractAcademic

Generation of universal "off-the-shelf'' chimeric antigen receptor (CAR)-engineered T cells

Prins, H. J., Katsarou, A., Shahrabi, A., Zweegman, S., Mutis, T. & Themeli, M., 1 Dec 2018, In : Human Gene Therapy. 29, 12, p. A120-A120

Research output: Contribution to journalMeeting AbstractAcademic

Hexameric Soluble Form of Pathogenic Protein from Human Endogenous Retrovirus (pHERV-W-Env) Specifically Extracted from MS Lesions.

Charvet, B., Gorter, R., Brunel, J., Pierquin, J., Glanzman, R. L., Amor, S. & Perron, H., Feb 2018, In : Multiple Sclerosis. 24, p. 135-135

Research output: Contribution to journalMeeting AbstractAcademic

High value genetic services through outcomes-based systems specifications

Puggina, A., Vojinovic, D., Demirkan, A., Pastorino, R., Damman, O., Parente, P., Lagerberg, T., van El, C. G., Meijers-Heijboer, H., Cornel, M., Jani, A. & Gray, M., Oct 2018, In : European Journal of Human Genetics. 26, p. 797-797

Research output: Contribution to journalMeeting AbstractAcademic

Implementing NIPT as part of a national prenatal screening program: The Dutch TRIDENT studies

Galjaard, R-J., Henneman, L., Macville, M., Bax, C., Bekker, M., De Die-Smulders, C., Feenstra, I., Hoffer, M., Den Hollander, N., Van Langen, I., Lichtenbelt, K., Lombardi, P., Van Maarle, M., Van Der Meij, K., Pieters, M., Schuring-Blom, H., Sikkel, E., Stevens, S., Suijkerbuijk, R., Van Der Ven, J. & 3 othersVan Opstal, D., Weiss, J. & Sistermans, E., 2018, In : Prenatal Diagnosis. 38

Research output: Contribution to journalMeeting AbstractAcademic

Insulin-like Growth Factor Binding Protein 7 Activates the Retinoid Acid Differentiation Pathway in Acute Myeloid Leukemia Cells

Van Gils, N., Verhagen, H. J. M. P., Rutten, A., Menezes, R. X., Tsui, M-L., Dekens, E., Denkers, F., Vermue, E., Janssen, J. J. W. M., Ossenkoppele, G. J. & Smit, L., 21 Nov 2018, In : Blood. 132, Suppl 1

Research output: Contribution to journalMeeting AbstractAcademic

Intradermal vaccination strategy targeting human Skin DC using melanoma specifc multivalent glyco-nanomers

Duinkerken, S., Schetters, S., Kalay, H., Ambrosini, M., Garcia-Vallejo, J. J. & van Kooyk, Y., May 2018, In : European Journal of Immunology. 48, p. 31-31

Research output: Contribution to journalMeeting AbstractAcademic

It's only one extra sample of blood: Offering prenatal carrier screening for sickle cell disease and thalassemia in a high-risk population

Holtkamp, K. C. A., Lakeman, P., Hader, H., Jans, S. M. J. P., Hoenderdos, M., Cornel, M. C., Peters, M. & Henneman, L., Oct 2018, In : European Journal of Human Genetics. 26, p. 790-791

Research output: Contribution to journalMeeting AbstractAcademic

Monozygotic twin similarities for AD biomarkers: the Twin60+study

den Braber, A., Boomsma, D. I., Konijnenberg, E., Ten Kate, M., Tomassen, J., Teunissen, C., Barkhof, F., Van Berckel, B., De Geus, E. J. C., Scheltens, P. & Visser, P. J., Nov 2018, In : Behavior Genetics. 48, 6, p. 465-465

Research output: Contribution to journalMeeting AbstractAcademic

Multiple sclerosis diagnosis is not the only determinant of neurofilament light protein fluctuations in serum

Bridel, C., Verberk, I., Heijst, H., Leurs, C., Killestein, J. & Teunissen, C., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 560-560

Research output: Contribution to journalMeeting AbstractAcademic

Specific patterns of thalamic functional connectivity changes related to disability and cognitive impairment in multiple sclerosis

Schoonheim, M. M., Pinter, D., Meijer, K. A., Eijlers, A. J. C., Pirpamer, L., Khalil, M., Pichler, A., Fuchs, S., Fazekas, F., Uitdehaag, B. M. J., Barkhof, F., Enzinger, C. & Geurts, J. J. G., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 613-614

Research output: Contribution to journalMeeting AbstractAcademic

Stable estimated live birth prevalence of Down syndrome in the Netherlands, 2000-2013

Tamminga, S., de Groot-van Mooren, M. D., Weijerman, M. E., Oepkes, D. & Cornel, M. C., Oct 2018, In : European Journal of Human Genetics. 26, p. 136-136

Research output: Contribution to journalMeeting AbstractAcademic

Successful Treatment of MYC rearrangement Positive Large B Cell Lymphoma Patients with R-CHOP21 Plus Lenalidomide: Results of a Multicenter Phase II HOVON Trial

Chamuleau, M. E. D., Nijland, M., Zijlstra, J. M., Mous, R., Lugtenburg, P. J., Dierickx, D., Imhoff, G. V., Vermaat, J., Bakunina, K., Marijt, E. W. A., Visser, O., Mandigers, C., Bilgin, Y., Burggraaff, C., Hoekstra, O., Jong, D. D. & Kersten, M. J., 21 Nov 2018, In : Blood. 132, Suppl 1, p. 786 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Targeting miRNA-551b, a "Stemness"-like microRNA, to Eradicate AML (Stem) Cells

Martiáñez, T., Van Gils, N., De Leeuw, D. C., Vermue, E., Rutten, A., Denkers, F., Verhagen, H. J. M. P., Janssen, J. J. W. M., Ossenkoppele, G. J., Jimenez, C. & Smit, L., 21 Nov 2018, In : Blood. 132, Suppl 1

Research output: Contribution to journalMeeting AbstractAcademic

The European Gen-Equip project to create accessible resources for genetics education in primary care: an account of the process, the challenges and the successes

Jackson, L., Cornel, M., Paneque, M., Stefansdottir, V., Turchetti, D., Curtisova, V., Lunt, P. W., Campos, M., Kent, A., Macek, M. . J., Houwink, E., O'Connor, A. & Skirton, H., Oct 2018, In : European Journal of Human Genetics. 26, p. 71-72

Research output: Contribution to journalMeeting AbstractAcademic

The Personalized PREvention of Chronic Diseases (PRECeDI) recommendations on Personalized Medicine

Pastorino, R., Adany, R., Barnhoorn, F., Boffetta, P., Boretti, F., Cornel, M., Van Duijn, C., Gray, M., Roldan, J., Villari, P., Zawati, M. & Boccia, S., Nov 2018, In : European Journal of Public Health. 28, p. 207-208

Research output: Contribution to journalMeeting AbstractAcademic