Amsterdam Neuroscience - Cellular and Molecular Mechanisms

Research Output

2020

A 30-Year Clinical and Magnetic Resonance Imaging Observational Study of Multiple Sclerosis and Clinically Isolated Syndromes

Chung, K. K., Altmann, D., Barkhof, F., Miszkiel, K., Brex, P. A., O'Riordan, J., Ebner, M., Prados, F., Cardoso, M. J., Vercauteren, T., Ourselin, S., Thompson, A., Ciccarelli, O. & Chard, D. T., Jan 2020, In : Annals of Neurology. 87, 1, p. 63-74 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Are Apathy and Depressive Symptoms Related to Vascular White Matter Hyperintensities in Severe Late Life Depression?

Oudega, M. L., Siddiqui, A., Wattjes, M. P., Barkhof, F., Kate, M. T., Muller, M., Bouckaert, F., Vandenbulcke, M., De Winter, F. L., Sienaert, P., Stek, M. L., Comijs, H. C., Korten, N. C. M., Emsell, L., Eikelenboom, P., Rhebergen, D., van Exel, E. & Dols, A., 1 Jan 2020, In : Journal of Geriatric Psychiatry and Neurology.

Research output: Contribution to journalArticleAcademicpeer-review

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 291 others, Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Hofmann, A., Jiménez, E., Kahn, J. P., Kassem, L., Kuo, P. H., Kato, T., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Tortorella, A., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., Colom, F., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O’Donovan, C., Ozaki, N., Ösby, U., Pfennig, A., Potash, J. B., Reif, A., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. V., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Ising, M., Jansen, R., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Maj, M., Turecki, G., Vieta, E., Veeh, J., Witt, S. H., Wright, A., Zandi, P. P., Mitchell, P. B., Bauer, M., Alda, M., Rietschel, M., McMahon, F. J., Schulze, T. G., Baune, B. T. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk (Nature Genetics, (2019), 51, 3, (404-413), 10.1038/s41588-018-0311-9)

Jansen, I. E., Savage, J. E., Watanabe, K., Bryois, J., Williams, D. M., Steinberg, S., Sealock, J., Karlsson, I. K., Hägg, S., Athanasiu, L., Voyle, N., Proitsi, P., Witoelar, A., Stringer, S., Aarsland, D., Almdahl, I. S., Andersen, F., Bergh, S., Bettella, F., Bjornsson, S. & 33 others, Brækhus, A., Bråthen, G., de Leeuw, C., Desikan, R. S., Djurovic, S., Dumitrescu, L., Fladby, T., Hohman, T. J., Jonsson, P. V., Kiddle, S. J., Rongve, A., Saltvedt, I., Sando, S. B., Selbæk, G., Shoai, M., Skene, N. G., Snaedal, J., Stordal, E., Ulstein, I. D., Wang, Y., White, L. R., Hardy, J., Hjerling-Leffler, J., Sullivan, P. F., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S., Andreassen, O. A. & Posthuma, D., 1 Jan 2020, In : Nature Genetics. 52, 3, 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Author Correction: Genetic mapping of cell type specificity for complex traits (Nature Communications, (2019), 10, 1, (3222), 10.1038/s41467-019-11181-1)

Watanabe, K., Mirkov, M. U., de Leeuw, C. A., van den Heuvel, M. P. & Posthuma, D., 1 Dec 2020, In : Nature Communications. 11, 1, 1718.

Research output: Contribution to journalErratumAcademicpeer-review

Open Access

Author Correction: A global overview of pleiotropy and genetic architecture in complex traits (Nature Genetics, (2019), 51, 9, (1339-1348), 10.1038/s41588-019-0481-0)

Watanabe, K., Stringer, S., Frei, O., Mirkov, M. U., de Leeuw, C., Polderman, T. J. C., van der Sluis, S., Andreassen, O. A., Neale, B. M. & Posthuma, D., 1 Jan 2020, In : Nature Genetics. 52, 3, 1 p.

Research output: Contribution to journalErratumAcademicpeer-review

Open Access

Author response: Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment

Ferro, D. A., van den Brink, H., Exalto, L. G., Boomsma, J. M. F., Barkhof, F., Prins, N. D., van der Flier, W. M. & Biessels, G. J., 18 Feb 2020, In : Neurology. 94, 7, p. 330 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bortezomib maintenance after R-CHOP, cytarabine and autologous stem cell transplantation in newly diagnosed patients with mantle cell lymphoma, results of a randomised phase II HOVON trial

Doorduijn, J. K., Zijlstra, J. M., Lugtenburg, P. J., Kersten, M. J., Böhmer, L. H., Minnema, M. C., MacKenzie, M. A., van Marwijk Kooij, R., de Jongh, E., Snijders, T. J. F., de Weerdt, O., van Gelder, M., Hoogendoorn, M., Leys, R. B. L., Kibbelaar, R. E., de Jong, D., Chitu, D. A., Van’t Veer, M. B. & Kluin-Nelemans, H. C., 1 Jan 2020, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain miliary enhancement

Bot, J. C. J., Mazzai, L., Hagenbeek, R. E., Ingala, S., van Oosten, B., Sanchez-Aliaga, E. & Barkhof, F., 2020, In : Neuroradiology. 62, 3, 18 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Breast Implant Prevalence in the Dutch Female Population Assessed by Chest Radiographs

de Boer, M., van Middelkoop, M., Hauptmann, M., van der Bijl, N., Bosmans, J. A. W., Hendriks-Brouwer, N., Schop, S. J., de Boer, J. P., Hijmering, N. J., Overbeek, L. I. H., Lobbes, M. B. I., Klazen, C. A. H., de Jong, D., Rakhorst, H. A., van der Hulst, R. R. W. J. & van Leeuwen, F. E., 2020, In : Aesthetic Surgery Journal. 40, 2, p. 156-164 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cerebral blood flow and cognitive functioning in patients with disorders along the heart–brain axis: Cerebral blood flow and the heart–brain axis

Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H. P., Kappelle, L. J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A. C., Prins, N. D., Biessels, G. J., Barkhof, F., van der Flier, W. M. & Heart–Brain Connection consortium, 1 Jan 2020, (Accepted/In press) In : Alzheimer's and Dementia: Translational Research and Clinical Interventions.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Characterization of Mechanical Signature of Eutopic Endometrial Stromal Cells of Endometriosis Patients

Altayyeb, A., Othman, E., Khashbah, M., Esmaeel, A., El-Mokhtar, M., Lambalk, C., Mijatovic, V. & Abdelgawad, M., 1 Jan 2020, In : Reproductive Sciences. 27, 1, p. 364-374 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comorbid amyloid-β pathology affects clinical and imaging features in VCD

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, M. J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., 1 Feb 2020, In : Alzheimers & Dementia. 16, 2, p. 354-364 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (Molecular Psychiatry, (2020), 10.1038/s41380-019-0546-6)

Coleman, J. R. I. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalErratumAcademicpeer-review

Open Access

Correction to: Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes (Metabolic Brain Disease, (2020), 35, 4, (601-614), 10.1007/s11011-020-00550-1)

Kirby, T., Walters, D. C., Brown, M., Jansen, E., Salomons, G. S., Turgeon, C., Rinaldo, P., Arning, E., Ashcraft, P., Bottiglieri, T., Roullet, J. B. & Gibson, K. M., 1 Jan 2020, (Accepted/In press) In : METABOLIC BRAIN DISEASE. 35, 5, 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

CSF cutoffs for MCI due to AD depend on APOEε4 carrier status

Marizzoni, M., Ferrari, C., Babiloni, C., Albani, D., Barkhof, F., Cavaliere, L., Didic, M., Forloni, G., Fusco, F., Galluzzi, S., Hensch, T., Jovicich, J., Marra, C., Molinuevo, J. L., Nobili, F., Parnetti, L., Payoux, P., Ranjeva, J. P., Ribaldi, F., Rolandi, E. & 10 others, Rossini, P. M., Salvatore, M., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J. C., Bordet, R., Blin, O. & Frisoni, G. B., 1 Jan 2020, In : Neurobiology of Aging. 89, 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

DDX5 potentiates HIV-1 transcription as a co-factor of Tat

Sithole, N., Williams, C. A., Abbink, T. E. M. & Lever, A. M. L., 30 Mar 2020, In : Retrovirology. 17, 1, 6.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Degree of genetic liability for Alzheimer's disease associated with specific proteomic profiles in cerebrospinal fluid

Alzheimer's Disease Neuroimaging Initiative, 24 Mar 2020, In : Neurobiology of Aging.

Research output: Contribution to journalArticleAcademicpeer-review

Distinct influence of different vascular risk factors on white matter brain lesions in multiple sclerosis

Geraldes, R., Juryńczyk, M., Dos Passos, G., Prichler, A., Chung, K., Hagens, M., Ruggieri, S., Huerga, E., Sastre-Garriga, J., Enzinger, C., Chard, D. T., Barkhof, F., Gasperini, C., Rovira, A., Deluca, G. C. & Palace, J., 1 Jan 2020, In : Journal of Neurology, Neurosurgery and Psychiatry. 91, 4, 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial

Chataway, J., De Angelis, F., Connick, P., Parker, R. A., Plantone, D., Doshi, A., John, N., Stutters, J., MacManus, D., Prados Carrasco, F., Barkhof, F., Ourselin, S., Braisher, M., Ross, M., Cranswick, G., Pavitt, S. H., Giovannoni, G., Gandini Wheeler-Kingshott, C. A., Hawkins, C., Sharrack, B. & 5 others, Bastow, R., Weir, C. J., Stallard, N., Chandran, S. & MS-SMART Investigators, 1 Mar 2020, In : The Lancet Neurology. 19, 3, p. 214-225 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

Gowrisankaran, S., Houy, S., del Castillo, J. G. P., Steubler, V., Gelker, M., Kroll, J., Pinheiro, P. S., Schwitters, D., Halbsgut, N., Pechstein, A., van Weering, J. R. T., Maritzen, T., Haucke, V., Raimundo, N., Sørensen, J. B. & Milosevic, I., 1 Dec 2020, In : Nature Communications. 11, 1, 1266.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone

Adams, K. L., Riparini, G., Banerjee, P., Breur, M., Bugiani, M. & Gallo, V., 1 Dec 2020, In : Nature Communications. 11, 1, 2138.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Evaluating severity of white matter lesions from computed tomography images with convolutional neural network

Pitkänen, J., Koikkalainen, J., Nieminen, T., Marinkovic, I., Curtze, S., Sibolt, G., Jokinen, H., Rueckert, D., Barkhof, F., Schmidt, R., Pantoni, L., Scheltens, P., Wahlund, L. O., Korvenoja, A., Lötjönen, J., Erkinjuntti, T. & Melkas, S., 1 Jan 2020, (Accepted/In press) In : Neuroradiology.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Facing privacy in neuroimaging: removing facial features degrades performance of image analysis methods

de Sitter, A., Visser, M., Brouwer, I., Cover, K. S., van Schijndel, R. A., Eijgelaar, R. S., Müller, D. M. J., Ropele, S., Kappos, L., Rovira, Filippi, M., Enzinger, C., Frederiksen, J., Ciccarelli, O., Guttmann, C. R. G., Wattjes, M. P., Witte, M. G., de Witt Hamer, P. C., Barkhof, F., Vrenken, H. & 2 others, MAGNIMS Study Group & Alzheimer’s Disease Neuroimaging Initiative, Feb 2020, In : European Radiology. 30, 2, p. 1062-1074 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Frontotemporal Dementia: Correlations Between Psychiatric Symptoms and Pathology

Scarioni, M., Gami-Patel, P., Timar, Y., Seelaar, H., van Swieten, J. C., Rozemuller, A. J. M., Dols, A., Scarpini, E., Galimberti, D., Hoozemans, J. J. M., Pijnenburg, Y. A. L., Dijkstra, A. A. & Netherlands Brain Bank, 1 Jan 2020, (Accepted/In press) In : Annals of Neurology. 87, 6, 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy

Prados, F., Moccia, M., Johnson, A., Yiannakas, M., Grussu, F., Cardoso, M. J., Ciccarelli, O., Ourselin, S., Barkhof, F. & Wheeler-Kingshott, C., 2020, In : NeuroImage. 209, 116489.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association study of the sensitivity to environmental stress and adversity neuroticism cluster

Nagel, M., Speed, D., van der Sluis, S. & Østergaard, S. D., 1 May 2020, In : Acta Psychiatrica Scandinavica. 141, 5, p. 476-478 3 p.

Research output: Contribution to journalLetterAcademicpeer-review

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 206 others, Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Howard, D. M., Ising, M., Jansen, R., Jones, I., Jones, L. A., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M., O’Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C., Breen, G. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Granulovacuolar degeneration bodies: red alert for neurons with MAPT/tau pathology

Wiersma, V. I. & Scheper, W., Jan 2020, In : Autophagy. 16, 1, p. 173-175 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Instrumented assessment of motor function in dyskinetic cerebral palsy: A systematic review

Haberfehlner, H., Goudriaan, M., Bonouvrié, L. A., Jansma, E. P., Harlaar, J., Vermeulen, R. J., Van Der Krogt, M. M. & Buizer, A. I., 5 Mar 2020, In : Journal of NeuroEngineering and Rehabilitation. 17, 1, 39.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Methylphenidate and galantamine in patients with vascular cognitive impairment-the proof-of-principle study STREAM-VCI

Leijenaar, J. F., Groeneveld, G. J., Klaassen, E. S., Leeuwis, A. E., Scheltens, P., Weinstein, H. C., van Gerven, J. M. A., Barkhof, F., van der Flier, W. M. & Prins, N. D., 2020, In : Alzheimer's Research & Therapy. 12, 1, p. 10 10.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

No evidence for cell-to-cell transmission of the unfolded protein response in cell culture

van Ziel, A. M., Wolzak, K., Nölle, A., Hoetjes, P. J., Berenjeno-Correa, E., van Anken, E., Struys, E. A. & Scheper, W., Jan 2020, In : Journal of Neurochemistry. 152, 2, p. 208-220 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

NOX2 Expression Is Increased in Keratinocytes after Burn Injury

Korkmaz, H. I., Ulrich, M. M. W., Çelik, G., Van Wieringen, W. N., Van Zuijlen, P. P. M., Krijnen, P. A. J. & Niessen, H. W. M., 19 Feb 2020, In : Journal of Burn Care and Research. 41, 2, p. 427-432 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Ongoing microstructural changes in the cervical cord underpin disability progression in early primary progressive multiple sclerosis

Cortese, R., Tur, C., Prados, F., Schneider, T., Kanber, B., Moccia, M., Wheeler-Kingshott, C. A. M. G., Thompson, A. J., Barkhof, F. & Ciccarelli, O., 2020, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Packaging RNA drugs into extracellular vesicles

van Eijndhoven, M. A. J., Baglio, S. R. & Pegtel, D. M., Jan 2020, In : Annals of Biomedical Engineering. 4, 1, p. 6-8 3 p.

Research output: Contribution to journalArticleAcademic

Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes

Kirby, T., Walters, D. C., Brown, M., Jansen, E., Salomons, G. S., Turgeon, C., Rinaldo, P., Arning, E., Ashcraft, P., Bottiglieri, T., Roullet, J. B. & Gibson, K. M., 1 Jan 2020, (Accepted/In press) In : METABOLIC BRAIN DISEASE. 35, 4, 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Premature expression of the decidualization marker prolactin is associated with repeated implantation failure

Berkhout, R. P., Lambalk, C. B., Repping, S., Hamer, G. & Mastenbroek, S., Apr 2020, In : Gynecological Endocrinology. 36, 4, p. 360-364 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prodromal Dementia with Lewy Bodies: Clinical Characterization and Predictors of Progression

van de Beek, M., van Steenoven, I., van der Zande, J. J., Barkhof, F., Teunissen, C. E., van der Flier, W. M. & Lemstra, A. W., 1 Jan 2020, In : Movement Disorders. 35, 5, 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

Varderidou-Minasian, S., Hinz, L., Hagemans, D., Posthuma, D., Altelaar, M. & Heine, V. M., 27 May 2020, In : Autism. 11, 1, p. 38

Research output: Contribution to journalArticleAcademicpeer-review

Real-time imaging of multivesicular body-plasma membrane fusion to quantify exosome release from single cells

Bebelman, M. P., Bun, P., Huveneers, S., van Niel, G., Pegtel, D. M. & Verweij, F. J., Jan 2020, In : Nature Protocols. 15, 1, p. 102-121 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy

Rhodius-Meester, H. F. M., van Maurik, I. S., Koikkalainen, J., Tolonen, A., Frederiksen, K. S., Hasselbalch, S. G., Soininen, H., Herukka, S-K., Remes, A. M., Teunissen, C. E., Barkhof, F., Pijnenburg, Y. A. L., Scheltens, P., Lötjönen, J. & van der Flier, W. M., 2020, In : PLoS ONE. 15, 1, p. e0226784 e0226784.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Synaptotagmin-1 and Doc2b Exhibit Distinct Membrane-Remodeling Mechanisms

Sorkin, R., Marchetti, M., Logtenberg, E., Piontek, M. C., Kerklingh, E., Brand, G., Voleti, R., Rizo, J., Roos, W. H., Groffen, A. J. & Wuite, G. J. L., 4 Feb 2020, In : Biophysical Journal. 118, 3, p. 643-656 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

The cardiovascular risk profile of middle-aged women with polycystic ovary syndrome

Meun, C., Gunning, M. N., Louwers, Y. V., Peters, H., Roos-Hesselink, J., Roeters van Lennep, J., Rueda Ochoa, O-L., Appelman, Y., Lambalk, N., Boersma, E., Kavousi, M., Fauser, B. C. JM., Laven, J. S. E. & on behalf of the CREW consortium, 1 Feb 2020, In : Clinical Endocrinology. 92, 2, p. 150-158 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The cardiovascular risk profile of middle age women previously diagnosed with premature ovarian insufficiency: A case-control study

Gunning, M. N., Meun, C., Van Rijn, B. B., Daan, N. M. P., Van Lennep, J. E. R., Appelman, Y., Boersma, E., Hofstra, L., Fauser, C. G. K. M., Rueda-Ochoa, O. L., Ikram, M. A., Kavousi, M., Lambalk, C. B., Eijkemans, M. J. C., Laven, J. S. E., Fauser, B. C. J. M. & on behalf of the CREW consortium, 1 Jan 2020, In : PLoS ONE. 15, 3, e0229576.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The genetic architecture of the human cerebral cortex

Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group, 20 Mar 2020, In : Science. 367, 6484, aay6690.

Research output: Contribution to journalArticleAcademicpeer-review

Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative

Simpson, H. B., van den Heuvel, O. A., Miguel, E. C., Reddy, Y. C. J., Stein, D. J., Lewis-Fernández, R., Shavitt, R. G., Lochner, C., Pouwels, P. J. W., Narayanawamy, J. C., Venkatasubramanian, G., Hezel, D. M., Vriend, C., Batistuzzo, M. C., Hoexter, M. Q., de Joode, N. T., Costa, D. L., de Mathis, M. A., Sheshachala, K., Narayan, M. & 15 others, van Balkom, A. J. L. M., Batelaan, N. M., Venkataram, S., Cherian, A., Marincowitz, C., Pannekoek, N., Stovezky, Y. R., Mare, K., Liu, F., Otaduy, M. C. G., Pastorello, B., Rao, R., Katechis, M., Van Meter, P. & Wall, M., 14 Feb 2020, In : BMC Psychiatry. 20, 1, p. 68 68.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Variants in NGLY1 lead to intellectual disability, myoclonus epilepsy, sensorimotor axonal polyneuropathy and mitochondrial dysfunction

Panneman, D. M., Wortmann, S. B., Haaxma, C. A., van Hasselt, P. M., Wolf, N. I., Hendriks, Y., Küsters, B., van Emst-de Vries, S., van de Westerlo, E., Koopman, W. J. H., Wintjes, L., van den Brandt, F., de Vries, M., Lefeber, D. J., Smeitink, J. A. M. & Rodenburg, R. J., 1 Apr 2020, In : Clinical Genetics. 97, 4, p. 556-566 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access