Amsterdam Neuroscience - Cellular and Molecular Mechanisms

Research Output

1989

Localization and imaging of radiolabelled monoclonal antibody against squamous‐cell carcinoma of the head and neck in tumor‐bearing nude mice

Quak, J. J., Balm, A. J. M., Brakkee, J. G. P., Scheper, R. J., Haisma, H. J., Braakhuis, B. J. M., Meijer, C. J. L. M. & Snow, G. B., 1 Jan 1989, In : International Journal of Cancer. 44, 3, p. 534-538 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

1990

A 22-kd surface antigen detected by monoclonal antibody E 48 is exclusively expressed in stratified squamous and transitional epithelia

Quak, J. J., Balm, A. J. M., Van Dongen, G. A. M. S., Brakkee, J. G. P., Scheper, R. J., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : American Journal of Pathology. 136, 1, p. 191-197 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of a 43‐kda nuclear antigen associated with proliferation by monoclonal antibody k 112

Quak, J. J., Dongen, G. V., Koken, M. A. E., Brakkee, J. G. P., Scheper, R. J., Balm, A. J. M., Jong, L. D., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : International Journal of Cancer. 46, 1, p. 50-55 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Production of a monoclonal antibody (K 931) to a squamous cell carcinoma associated antigen identified as the 17-1A antigen

Quak, J. J., Van Dongen, G., Brakkee, J. G. P., Hayashida, D. J., Balm, A. J. M., Snow, G. B. & Meijer, C. J. L. M., 1 Jan 1990, In : Hybridoma. 9, 4, p. 377-387 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Production of Monoclonal Antibodies to Squamous Cell Carcinoma Antigens

Quak, J. J., Balm, F. J. M., Brakkee, J. G. P., Scheper, R. J., Meijer, C. J. L. M. & Snow, G. B., 1 Jan 1990, In : Archives of Otolaryngology--Head and Neck Surgery. 116, 2, p. 181-185 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Three sensitive methods for the detection of cytomegalovirus in lung tissue of patients with interstitial pneumonitis

Jiwa, M., Steenbergen, RDM., Zwaan, F. E., Kluin, P. M., Raap, AK. & Ploeg van der, M., 1 Apr 1990, In : American Journal of Clinical Pathology. 93, 4, p. 491 494 p.

Research output: Contribution to journalArticleAcademicpeer-review

1991

Detection of Squamous Cell Carcinoma Xenografts in Nude Mice by Radiolabeled Monoclonal Antibody E48

Quak, J. J., Gerretsen, M., Schrijvers, A. H. G. J., Meijer, C. J. L. M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1991, In : Archives of Otolaryngology--Head and Neck Surgery. 117, 11, p. 1287-1291 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Release of azurophilic granule contents in fMLP-stimulated neutrophils requires two activation signals, one of which is a rise in cytosolic free Ca2+

Niessen, H. W., Kuijpers, T. W., Roos, D. & Verhoeven, A. J., 1991, In : Cellular Signalling. 3, 6, p. 625-33 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1992

Differential up-regulation of specific and azurophilic granule membrane markers in electropermeabilized neutrophils

Niessen, H. W. & Verhoeven, A. J., Sep 1992, In : Cellular Signalling. 4, 5, p. 501-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression and characterization of two differentiation antigens in human stratified squamous epithelia and carcinomas

Quak, J. J., Schrijvers, A. H. G. J., Brakkee, J. G. P., Davis, H. D., Scheper, R. J., Meijer, C. J. L. M., Snow, G. B. & van Donoen, G. A. M. S., 1 Jan 1992, In : International Journal of Cancer. 50, 4, p. 507-513 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with131i-labelled monoclonal antibody e48 igg

Gerretsen, M., Schrijvers, A. H. G. J., Van Walsum, M., Braakhuis, B. J. M., Quak, J. J., Meijer, C., Snow, G. B. & Van Dongen, G. A. M. S., 1 Jan 1992, In : British Journal of Cancer. 66, 3, p. 496-502 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Use of monoclonal antibody E48 in diagnosing transitional cell carcinoma of urinary bladder

Torenbeek, R., Blomjous, C. E. M., Quak, J. J., Ybema, S. & Meijer, C. J. L. M., 1 Jan 1992, In : Journal of Clinical Pathology. 45, 4, p. 303-307 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1993

FOLIUMZUUR VOOR ALLE FERTIELE VROUWEN? [3]

Translated title of the contribution: Folic acid for all fertile women? [3]Van Dongen, A. M., Cornel, M. C., De Jong-Van Den Berg, L. T. W., Steegers-Theunissen, R. P. M., Ten Kate, L. P., Roegholt, L. P., Barkhof, F., Boers, G. H. J. & Eskes, T. K. A. B., 1 Jan 1993, In : Nederlands Tijdschrift voor Geneeskunde. 137, 33, p. 1682-1684 3 p.

Research output: Contribution to journalLetterAcademicpeer-review

Localization of E2A mRNA expression in developing and adult rat tissues

Roberts, VJ., Steenbergen, RDM. & Murre, CJ., 15 Aug 1993, In : Proceedings of the National Academy of Sciences. p. 7583-7587

Research output: Contribution to journalArticleAcademicpeer-review

1994

Analysis of p53 status in tonsillar carcinomas associated with human papillomavirus

Snijders, P. J. F., Steenbergen, R. D. M., Top, B., Scott, S. D., Meijer, C. J. L. M. & Walboomers, J. M. M., 1 Jan 1994, In : Journal of General Virology. 75, 10, p. 2769-2775 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fluoride prevents degranulation of the azurophilic and specific granules in electropermeabilized neutrophils

Niessen, H. W., Kessels, G. C. & Verhoeven, A. J., Apr 1994, In : Journal of Leukocyte Biology. 55, 4, p. 489-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immunoelectron microscopy reveals significant granule fusion upon stimulation of electropermeabilized human neutrophils

Niessen, H. W., Onderwater, J. J., Koerten, H. K., Ginsel, L. A. & Verhoeven, A. J., Jan 1994, In : Cellular Signalling. 6, 1, p. 47-58 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Role of protein phosphorylation in the degranulation of electropermeabilized human neutrophils

Niessen, H. W. & Verhoeven, A. J., 8 Sep 1994, In : Biochimica et Biophysica Acta. Reviews on Cancer. 1223, 2, p. 267-73 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1995

Integrated Human Papillomavirus Type 16 and Loss of Heterozygosity at 11q22 and 18q21 in an Oral Carcinoma and Its Derivative Cell Line

Steenbergen, R. D. M., Walboomers, J. M. M., Meijer, C. J. L. M., Snijders, P. J. F., Hermsen, M. A. J. A., Joenje, H. & Arwert, F., 15 Nov 1995, In : Cancer Research. 55, 22, p. 5465-5471 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiple Sclerosis Therapy: A Practical Guide

van Oosten, B. W., Truyen, L., Barkhof, F. & Polman, C. H., 1 Jan 1995, In : Drugs. 49, 2, p. 200-212 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

1996

Accumulation of hypointense lesions ('black holes') on T1 spin-echo MRI correlates with disease progression in multiple sclerosis

Truyen, L., Van Waesberghe, J. H. T. M., Van Walderveen, M. A. A., Van Oosten, B. W., Polman, C. H., Hommes, O. R., Adèr, H. J. A. & Barkhof, F., 1 Jan 1996, In : Neurology. 47, 6, p. 1469-1476 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Age-dependence of human papillomavirus DNA presence in oral squamous cell carcinomas

Cruz, I. B. F., Snijders, P. J. F., Steenbergen, R. D. M., Meijer, C. J. L. M., Snow, G. B., Walboomers, J. M. M. & Van Der Waal, I., 1 Jan 1996, In : European Journal of Cancer Part B: Oral Oncology. 32, 1, p. 55-62 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Analysis of IgG reactivity against Human Papillomavirus type-16 E7 in patients with cervical intraepithelial neoplasia indicates an association with clearance of viral infection: results of a prospective study

de Gruijl, T. D., Bontkes, H. J., Walboomers, J. M., Stukart, M. J., Robbesom, A. A., von Blomberg-van der Flier, B. M., Herbrink, P., Remmink, A. J., Verheijen, R. H., Helmerhorst, T. J., Meijer, C. J. & Scheper, R. J., 11 Dec 1996, In : International Journal of Cancer. 68, 6, p. 731-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A phase II trial of anti-CD4 antibodies in the treatment of multiple sclerosis

Van Oosten, B. W., Lai, M., Barkhof, F., Miller, D. H., Moseley, I. F., Thompson, A. J., Hodgkinson, S. & Polman, C. H., 1 Jan 1996, In : Multiple Sclerosis. 1, 6, p. 339-342 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression of epstein-barr virus encoded nuclear antigen 1 in benign and malignant tissues harbouring EBV

Oudejans, J. J., Dukers, D. F., Jiwa, N. M., van den Brule, A. J., Grässer, F. A., de Bruin, P. C., Horstman, A., Vos, W., van Gorp, J., Middeldorp, J. M. & Meijer, C. J., Nov 1996, In : Journal of Clinical Pathology. 49, 11, p. 897-902 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2

Van Oosten, B. W., Barkhof, F., Truyen, L., Boringa, J. B., Bertelsmann, F. W., Von Blomberg, B. M. E., Woody, J. N., Hartung, H. P. & Polman, C. H., 1 Jan 1996, In : Neurology. 47, 6, p. 1531-1534 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

T cell proliferative responses against human papillomavirus type 16 E7 oncoprotein are most prominent in cervical intraepithelial neoplasia patients with a persistent viral infection

de Gruijl, T. D., Bontkes, H. J., Stukart, M. J., Walboomers, J. M., Remmink, A. J., Verheijen, R. H., Helmerhorst, T. J., Meijer, C. J. & Scheper, R. J., Sep 1996, In : Journal of General Virology. 77 ( Pt 9), p. 2183-91 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Transition of human papillomavirus type 16 and 18 transfected human foreskin keratinocytes towards immortality: Activation of telomerase and allele losses at 3p, 10p, 11q and/or 18q

Steenbergen, R. D. M., Walboomers, J. M. M., Meijer, C. J. L. M., Van Der Raaij-Helmer, E. M. H., Parker, J. N., Chow, L. T., Broker, T. R. & Snijders, P. J. F., 25 Oct 1996, In : Oncogene. 13, 6, p. 1249-1257 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1997

Activated cytotoxic T cells as prognostic marker in Hodgkin's disease

Oudejans, J. J., Jiwa, N. M., Kummer, J. A., Ossenkoppele, G. J., van Heerde, P., Baars, J. W., Kluin, P. M., Kluin-Nelemans, J. C., van Diest, P. J., Middeldorp, J. M. & Meijer, C. J., 15 Feb 1997, In : Blood. 89, 4, p. 1376-82 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Assessment of cytotoxic T-lymphocyte phenotype using the specific markers granzyme B and TIA-1 in cervical neoplastic lesions

Bontkes, H. J., de Gruijl, T. D., Walboomers, J. M., van den Muysenberg, A. J., Gunther, A. W., Scheper, R. J., Meijer, C. J. & Kummer, J. A., 1997, In : British Journal of Cancer. 76, 10, p. 1353-1360 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

C-reactive protein colocalizes with complement in human hearts during acute myocardial infarction

Lagrand, W. K., Niessen, H. W., Wolbink, G. J., Jaspars, L. H., Visser, C. A., Verheugt, F. W., Meijer, C. J. & Hack, C. E., 7 Jan 1997, In : Circulation. 95, 1, p. 97-103 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin G responses against human papillomavirus type 16 virus-like particles in a prospective nonintervention cohort study of women with cervical intraepithelial neoplasia

de Gruijl, T. D., Bontkes, H. J., Walboomers, J. M., Schiller, J. T., Stukart, M. J., Groot, B. S., Chabaud, M. M., Remmink, A. J., Verheijen, R. H., Helmerhorst, T. J., Meijer, C. J. & Scheper, R. J., 7 May 1997, In : Journal of the National Cancer Institute. 89, 9, p. 630-8 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-2 therapy does not exacerbate multiple sclerosis

Van Oosten, B. W., Uitdehaag, B. M. J., Barkhof, F., Hartung, H. P., Wagstaff, J. & Polman, C. H., 1 Jan 1997, In : Neurology. 49, 2, p. 633-634 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Presence of Epstein-Barr virus latency type III at the single cell level in post-transplantation lymphoproliferative disorders and AIDS related lymphomas

Brink, A. A., Dukers, D. F., van den Brule, A. J., Oudejans, J. J., Middeldorp, J. M., Meijer, C. J. & Jiwa, M., Nov 1997, In : Journal of Clinical Pathology. 50, 11, p. 911-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: Results of a randomized, double-blind, placebo-controlled, MR- monitored phase II trial

Van Oosten, B. W., Lai, M., Hodgkinson, S., Barkhof, F., Miller, D. H., Moseley, I. F., Thompson, A. J., Rudge, P., McDougall, A., McLeod, J. G., Adèr, H. J. & Polman, C. H., 1 Jan 1997, In : Neurology. 49, 2, p. 351-357 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1998

99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein

Hendrikse, N. H., Franssen, E. J. F., Van Der Graaf, W. T. A., Meijer, C., Piers, D. A., Vaalburg, W. & De Vries, E. G. E., 1 Jan 1998, In : British Journal of Cancer. 77, 3, p. 353-358 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Choosing drug therapy for multiple sclerosis. An update

Van Oosten, B. W., Truyen, L., Barkhof, F. & Polman, C. H., 7 Nov 1998, In : Drugs. 56, 4, p. 555-569 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Complement c1-inhibitor expression in Alzheimer's disease

Veerhuis, R., Janssen, I., Hoozemans, JJM., De Groot, CJA., Hack, CE. & Eikelenboom, P., Sep 1998, In : Acta Neuropathologica. 96, 3, p. 287-296

Research output: Contribution to journalArticleAcademicpeer-review

Differential T helper cell responses to human papillomavirus type 16 E7 related to viral clearance or persistence in patients with cervical neoplasia: a longitudinal study

de Gruijl, T. D., Bontkes, H. J., Walboomers, J. M., Stukart, M. J., Doekhie, F. S., Remmink, A. J., Helmerhorst, T. J., Verheijen, R. H., Duggan-Keen, M. F., Stern, P. L., Meijer, C. J. & Scheper, R. J., 15 Apr 1998, In : Cancer Research. 58, 8, p. 1700-6 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hemidesmosome formation is initiated by the β4 integrin subunit, requires complex formation of β4 and HD1/plectin, and involves a direct interaction between β4 and the bullous pemphigoid antigen 180

Schaapveld, R. Q. J., Borradori, L., Geerts, D., Van Leusden, M. R., Kuikman, I., Nievers, M. G., Niessen, C. M., Steenbergen, R. D. M., Snijders, P. J. F. & Sonnenberg, A., 13 Jul 1998, In : Journal of Cell Biology. 142, 1, p. 271-284 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

HPV 16 infection and progression of cervical intra-epithelial neoplasia: analysis of HLA polymorphism and HPV 16 E6 sequence variants

Bontkes, H. J., van Duin, M., de Gruijl, T. D., Duggan-Keen, M. F., Walboomers, J. M., Stukart, M. J., Verheijen, R. H., Helmerhorst, T. J., Meijer, C. J., Scheper, R. J., Stevens, F. R., Dyer, P. A., Sinnott, P. & Stern, P. L., 5 Oct 1998, In : International Journal of Cancer. 78, 2, p. 166-71 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increased production of tumor necrosis factor α, and not of interferon γ, preceding disease activity in patients with multiple sclerosis

Van Oosten, B. W., Barkhof, F., Scholten, P. E. T., Von Blomberg, B. M. E., Adèr, H. J. & Polman, C. H., 1 Jun 1998, In : Archives of Neurology. 55, 6, p. 793-798 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes

Steenbergen, R. D. M., Hermsen, M. A. J. A., Walboomers, J. M. M., Meijer, G. A., Baak, J. P. A., Meijer, C. J. L. M. & Snijders, P. J. F., 30 Jun 1998, In : International Journal of Cancer. 76, 3, p. 412-417 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nucleic acid sequence-based amplification, a new method for analysis of spliced and unspliced Epstein-Barr virus latent transcripts, and its comparison with reverse transcriptase PCR

Brink, A. A., Vervoort, M. B., Middeldorp, J. M., Meijer, C. J. & van den Brule, A. J., Nov 1998, In : Journal of Clinical Microbiology. 36, 11, p. 3164-9 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation

Meijer, G. A., Hermsen, M. A., Baak, J. P., van Diest, P. J., Meuwissen, S. G., Beliën, J. A., Hoovers, J. M., Joenje, H., Snijders, P. J. & Walboomers, J. M., Dec 1998, In : Journal of Clinical Pathology. 51, 12, p. 901-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Specific HLA class I down-regulation is an early event in cervical dysplasia associated with clinical progression

Bontkes, H. J., Walboomers, J. M., Meijer, C. J., Helmerhorst, T. J. & Stern, P. L., 17 Jan 1998, In : Lancet. 351, 9097, p. 187-8 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: Strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA

Snijders, P. J. F., Van Duin, M., Walboomers, J. M. M., Steenbergen, R. D. M., Risse, E. K. J., Helmerhorst, T. J. M., Verheijen, R. H. M. & Meijer, C. J. L. M., 1 Sep 1998, In : Cancer Research. 58, 17, p. 3812-3818 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Viral E6-E7 transcription in the basal layer of organotypic cultures without apparent p21cip1 protein precedes immortalization of human papillomavirus type 16- and 18-transfected human keratinocytes

Steenbergen, R. D. M., Parker, J. N., Isern, S., Snijders, P. J. F., Walboomers, J. M. M., Meijer, C. J. L. M., Broker, T. R. & Chow, L. T., 1 Jan 1998, In : Journal of Virology. 72, 1, p. 749-757 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1999

C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?

Lagrand, W. K., Visser, C. A., Hermens, W. T., Niessen, H. W., Verheugt, F. W., Wolbink, G. J. & Hack, C. E., 6 Jul 1999, In : Circulation. 100, 1, p. 96-102 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review