Amsterdam Neuroscience - Cellular and Molecular Mechanisms

Research Output

2018

Severe lactic acidosis associated with a suspected succinic semialdehyde dehydrogenase (SSADH) deficiency in a young Chihuahua dog

Kelmer, E., Gibson, K. M., Jakobs, C., Struys, E., Shelton, G. D., Aroch, I. & O’Brien, D. P., 2018, In : Israel Journal of Veterinary Medicine. 73, 2, p. 43-48

Research output: Contribution to journalArticleAcademicpeer-review

SICT: automated detection and supervised inspection of fast Ca2+ transients

Mancini, R., van der Bijl, T., Bourgeois-Jaarsma, Q., Lasabuda, R. & Groffen, A. J., 2018, In : Scientific Reports. 8, 1, 15523.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Slowly Progressive Psychiatric Symptoms: Think Metachromatic Leukodystrophy

van Rappard, D. F., de Vries, A. L. C., Oostrom, K. J., Boelens, J. J., Hollak, C. E. M., van der Knaap, M. S. & Wolf, N. I., 2018, In : Journal of the American Academy of Child and Adolescent Psychiatry. 57, 2, p. 86-95

Research output: Contribution to journalEditorialAcademicpeer-review

Specific patterns of thalamic functional connectivity changes related to disability and cognitive impairment in multiple sclerosis

Schoonheim, M. M., Pinter, D., Meijer, K. A., Eijlers, A. J. C., Pirpamer, L., Khalil, M., Pichler, A., Fuchs, S., Fazekas, F., Uitdehaag, B. M. J., Barkhof, F., Enzinger, C. & Geurts, J. J. G., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 613-614

Research output: Contribution to journalMeeting AbstractAcademic

Sporadic Fatal Insomnia in Europe: Phenotypic Features and Diagnostic Challenges

Abu-Rumeileh, S., Redaelli, V., Baiardi, S., Mackenzie, G., Windl, O., Ritchie, D. L., Didato, G., Hernandez-Vara, J., Rossi, M., Capellari, S., Imperiale, D., Rizzone, M. G., Belotti, A., Sorbi, S., Rozemuller, A. J. M., Cortelli, P., Gelpi, E., Will, R. G., Zerr, I., Giaccone, G. & 1 others, Parchi, P., 1 Sep 2018, In : Annals of Neurology. 84, 3, p. 347-360 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

StemBell therapy stabilizes atherosclerotic plaques after myocardial infarction

Woudstra, L., Meinster, E., VAN Haren, L., Kay, A. M., Koopman, M., Belien, J. A. M., Morrison, M. C., VAN Rossum, A. C., Helder, M. N., Juffermans, L. J. M., Niessen, H. W. M. & Krijnen, P. A. J., Sep 2018, In : Cytotherapy. 20, 9, p. 1143-1154 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody

Zhang, H., Zhu, X., Pascual, G., Wadia, J. S., Keogh, E., Hoozemans, J. J., Siregar, B., Inganäs, H., Stoop, E. J. M., Goudsmit, J., Apetri, A., Koudstaal, W. & Wilson, I. A., 2018, In : Structure. 26, 12, p. 1626-1634.e4

Research output: Contribution to journalArticleAcademicpeer-review

Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease

Mercado, G., Castillo, V., Soto, P., López, N., Axten, J. M., Sardi, S. P., Hoozemans, J. J. M. & Hetz, C., 1 Apr 2018, In : Neurobiology of Disease. 112, p. 136-148 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Biological Contributions to Gender Identity and Gender Diversity: Bringing Data to the Table

Polderman, T. J. C., Kreukels, B. P. C., Irwig, M. S., Beach, L., Chan, Y. M., Derks, E. M., Esteva, I., Ehrenfeld, J., Heijer, M. D., Posthuma, D., Raynor, L., Tishelman, A. & Davis, L. K., 1 Mar 2018, In : Behavior Genetics. 48, 2, p. 95-108 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The diagnostic accuracy of methylation markers in urine for the detection of bladder cancer: a systematic review

Bosschieter, J., Lutz, C., Segerink, L. I., Vis, A. N., Zwarthoff, E. C., A van Moorselaar, R. J., van Rhijn, B. W., Heymans, M. W., Jansma, E. P., Steenbergen, R. D. & Nieuwenhuijzen, J. A., May 2018, In : Epigenomics. 10, 5, p. 673-687 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effect of adverse intrauterine conditions, early childhood growth and famine exposure on age at menopause: A systematic review

Sadrzadeh, S., Verschuuren, M., Schoonmade, L. J., Lambalk, C. B. & Painter, R. C., 2018, In : Journal of Developmental Origins of Health and Disease. 9, 2, p. 127-136

Research output: Contribution to journalReview articleAcademicpeer-review

The effect of ART on cervical cancer precursor lesions

de Vries, H. J. C. & Steenbergen, R. D. M., Jan 2018, In : The Lancet HIV. 5, 1, p. e6-e8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The FOAM study: Is Hysterosalpingo foam sonography (HyFoSy) a cost-effective alternative for hysterosalpingography (HSG) in assessing tubal patency in subfertile women? Study protocol for a randomized controlled trial

van Rijswijk, J., van Welie, N., Dreyer, K., van Hooff, M. H. A., de Bruin, J. P., Verhoeve, H. R., Mol, F., Kleiman-Broeze, K. A., Traas, M. A. F., Muijsers, G. J. J. M., Manger, A. P., Gianotten, J., de Koning, C. H., Koning, A. M. H., Bayram, N., van der Ham, D. P., Vrouenraets, F. P. J. M., Kalafusova, M., van de Laar, B. I. G., Kaijser, J. & 16 others, van Oostwaard, M. F., Meijer, W. J., Broekmans, F. J. M., Valkenburg, O., van der Voet, L. F., van Disseldorp, J., Lambers, M. J., Peters, H. E., Lier, M. C. I., Lambalk, C. B., van Wely, M., Bossuyt, P. M. M., Stoker, J., van der Veen, F., Mol, B. W. J. & Mijatovic, V., 9 May 2018, In : BMC Women's Health. 18, 1

Research output: Contribution to journalArticleAcademicpeer-review

The Healthy and Diseased Microenvironments Regulate Oligodendrocyte Properties: Implications for Regenerative Medicine

Leferink, P. S. & Heine, V. M., 1 Jan 2018, In : American Journal of Pathology. 188, 1, p. 39-52 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The molecular landscape of head and neck cancer

Leemans, C. R., Snijders, P. J. F. & Brakenhoff, R. H., 2018, In : Nature Reviews Cancer. 18, 5, p. 269-282

Research output: Contribution to journalReview articleAcademicpeer-review

The natural history of Vanishing White Matter

Hamilton, E. M. C., Uitdehaag, B. M. J., Lissenberg-Witte, B. I., van der Knaap, M. S. & VWM Research Group, 6 Sep 2018, In : Annals of Neurology. 84, 2, p. 274-288

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The role of genetic polymorphisms in the thymidylate synthase (TYMS) gene in methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia

Oosterom, N., Berrevoets, M., den Hoed, M. A. H., Zolk, O., Hoerning, S., Pluijm, S. M. F., Pieters, R., de Jonge, R., Tissing, W. J. E., van den Heuvel-Eibrink, M. M. & Heil, S. G., 2018, In : Pharmacogenetics and Genomics. 28, 10, p. 223-229

Research output: Contribution to journalArticleAcademicpeer-review

The when, what & how of measuring vitamin D metabolism in clinical medicine

Dirks, N. F., Ackermans, M. T., Lips, P., de Jongh, R. T., Vervloet, M. G., de Jonge, R. & Heijboer, A. C., 13 Apr 2018, In : Nutrients. 10, 4, 482.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory

Verfaillie, S. C. J., Slot, R. E., Tijms, B. M., Bouwman, F., Benedictus, M. R., Overbeek, J. M., Koene, T., Vrenken, H., Scheltens, P., Barkhof, F. & van der Flier, W. M., 1 Jan 2018, In : Neurobiology of Aging. 61, p. 238-244 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Three-tiered score for Ki-67 and p16 improves accuracy and reproducibility of grading CIN lesions

van Zummeren, M., Leeman, A., Kremer, W. W., Bleeker, M. C. G., Jenkins, D., van de Sandt, M., Heideman, D. A. M., Steenbergen, R., Snijders, P. J. F., Quint, W. G. V., Berkhof, J. & Meijer, C. J. L. M., 1 Nov 2018, In : Journal of Clinical Pathology. 71, 11, p. 981-988 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Three VCP Mutations in Patients with Frontotemporal Dementia

Wong, T. H., Pottier, C., Hondius, D. C., Meeter, L. H. H., van Rooij, J. G. J., Melhem, S., van Minkelen, R., van Duijn, C. M., Rozemuller, A. J. M., Seelaar, H., Rademakers, R. & van Swieten, J. C., 2018, In : Journal of Alzheimer's Disease. 65, 4, p. 1139-1146

Research output: Contribution to journalArticleAcademicpeer-review

Towards the molecular mechanism of vanishing white matter

Wisse, L. E., 2018, 214 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University Amsterdam

Transplantation, gene therapy and intestinal pathology in MNGIE patients and mice

Yadak, R., Boot, M. V., van Til, N. P., Cazals-Hatem, D., Finkenstedt, A., Bogaerts, E., de Coo, I. F. & Bugiani, M., 2018, In : Bmc Gastroenterology. 18, 1, 149.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Treatment effect of oil-based contrast at HSG is dependent on pain at HSG but not on volume of contrast

van Welie, N., Dreyer, K., van Rijswijk, J., Verhoeve, H. R., Goddijn, M., Nap, A. W., Smeenk, J. M., Traas, M. A., Lambalk, C. B., Hompes, P., Mijatovic, V. & Mol, B. W., 13 Sep 2018, In : Fertility and Sterility. 110, 4, p. e40

Research output: Contribution to journalArticleAcademic

Treatment outcome of creatine transporter deficiency: international retrospective cohort study

Bruun, T. U. J., Sidky, S., Bandeira, A. O., Debray, F-G., Ficicioglu, C., Goldstein, J., Joost, K., Koeberl, D. D., Luísa, D., Nassogne, M-C., O’Sullivan, S., Õunap, K., Schulze, A., van Maldergem, L., Salomons, G. S. & Mercimek-Andrews, S., 2018, In : METABOLIC BRAIN DISEASE. 33, 3, p. 875-884

Research output: Contribution to journalArticleAcademicpeer-review

Treatment outcome of twenty-two patients with guanidinoacetate methyltransferase deficiency: An international retrospective cohort study

Khaikin, Y., Sidky, S., Abdenur, J., Anastasi, A., Ballhausen, D., Buoni, S., Chan, A., Cheillan, D., Dorison, N., Goldenberg, A., Goldstein, J., Hofstede, F. C., Jacquemont, M-L., Koeberl, D. D., Lion-Francois, L., Lund, A. M., Mention, K., Mundy, H., O'Rourke, D., Pitelet, G. & 6 others, Raspall-Chaure, M., Tassini, M., Billette de Villemeur, T., Williams, M., Salomons, G. S. & Mercimek-Andrews, S., 2018, In : European Journal of Paediatric Neurology. 22, 3, p. 369-379

Research output: Contribution to journalArticleAcademicpeer-review

Triage of high-risk HPV-positive women in population-based screening by miRNA expression analysis in cervical scrapes; a feasibility study

Babion, I., Snoek, B. C., Novianti, P. W., Jaspers, A., van Trommel, N., Heideman, D. A. M., Meijer, C. J. L. M., Snijders, P. J. F., Steenbergen, R. D. M. & Wilting, S. M., 2018, In : Clinical epigenetics. 10, p. 76

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly

Meijer, M., Dörr, B., Lammertse, H. C., Blithikioti, C., van Weering, J. R., Toonen, R. F., Söllner, T. H. & Verhage, M., 17 Jan 2018, In : EMBO Journal. 37, 2, p. 300-320 21 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

UFM1 founder mutation in the Roma population causes severe variant of Hypomyelination with Atrophy of the Basal ganglia and Cerebellum (H-ABC)

Hamilton, E. M., Bertini, E., Kalaydjieva, L., Morar, B., Dojcakova, D., Diodato, D., Wolf, N., Waisfisz, Q., Abbink, E. & van der Knaap, M. S., Jun 2018, In : European Journal of Neurology. 25, p. 31-32

Research output: Contribution to journalMeeting AbstractAcademic

Urgent challenges in quantification and interpretation of brain grey matter atrophy in individual MS patients using MRI

Amiri, H., de Sitter, A., Bendfeldt, K., Battaglini, M., Wheeler-Kingshott, C. A. M. G., Calabrese, M., Geurts, J. J. G., Rocca, M. A., Sastre-Garriga, J., Enzinger, C., de Stefano, N., Filippi, M., Rovira, A., Barkhof, F. & Vrenken, H., 2018, In : NeuroImage: Clinical. 19, p. 466-475

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Vanishing white matter: a leukodystrophy due to astrocytic dysfunction

Bugiani, M., Vuong, C., Breur, M. & van der Knaap, M. S., 2018, In : Brain Pathology. 28, 3, p. 408-421

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin D attenuates endothelial dysfunction in uremic rats and maintains human endothelial stability

Cuenca, M. V., Ferrantelli, E., Meinster, E., Pouw, S. M., Kovačević, I., de Menezes, R. X., Niessen, H. W., Beelen, R. H. J., Hordijk, P. L. & Vervloet, M. G., 1 Sep 2018, In : Journal of the American Heart Association. 7, 17, e008776.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

VPS35 depletion does not impair presynaptic structure and function

Vazquez-Sanchez, S., Bobeldijk, S., Dekker, M. P., van Keimpema, L. & van Weering, J. R. T., 2018, In : Scientific Reports. 8, 1, 2996.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi

Emperador-Melero, J., Huson, V., van Weering, J., Bollmann, C., Fischer von Mollard, G., Toonen, R. F. & Verhage, M., 2018, In : Nature Communications. 9, 1, 3421.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Whole Exon Deletion in the GFAP Gene Is a Novel Molecular Mechanism Causing Alexander Disease

Green, L., Berry, I. R., Childs, A. M., Mccullagh, H., Jose, S., Warren, D., Craven, I., Camm, N., Prescott, K., van der Knaap, M. S., Sheridan, E. & Livingston, J. H., 1 Apr 2018, In : Neuropediatrics. 49, 2, p. 118-122 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

β-Catenin in the Adult Visual Cortex Regulates NMDA-Receptor Function and Visual Responses

Saiepour, M. H., Min, R., Kamphuis, W., Heimel, J. A. & Levelt, C. N., 1 Apr 2018, In : Cerebral Cortex. 28, 4, p. 1183-1194 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System

Vrij-Van Den Bos, S., Hol, J. A., La Piana, R., Harting, I., Vanderver, A., Barkhof, F., Cayami, F., Van Wieringen, W. N., Pouwels, P. J. W., Van Der Knaap, M. S., Bernard, G. & Wolf, N. I., 1 Jun 2017, In : Neuropediatrics. 48, 3, p. 152-160 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

A data-driven statistical model that estimates measurement uncertainty improves interpretation of ADC reproducibility: A multi-site study of liver metastases

Pathak, R., Ragheb, H., Thacker, N. A., Morris, D. M., Amiri, H., Kuijer, J., Desouza, N. M., Heerschap, A. & Jackson, A., 1 Dec 2017, In : Scientific Reports. 7, 1, 14084.

Research output: Contribution to journalArticleAcademicpeer-review

Alexander Disease: A Leukodystrophy That May Mimic Brain Tumor

Tavasoli, A., Armangue, T., Ho, C. Y., Whitehead, M., Bornhorst, M., Rhee, J., Hwang, E. I., Wells, E. M., Packer, R., Van Der Knaap, M. S., Bugiani, M. & Vanderver, A., 2017, In : Journal of Child Neurology. 32, 2, p. 184-187 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Alpha-Synuclein Induces the Unfolded Protein Response in Parkinson's Disease SNCA Triplication iPSC-Derived Neurons

Heman-Ackah, S. M., Manzano, R., Hoozemans, J. J. M., Scheper, W., Flynn, R., Haerty, W., Cowley, S. A., Bassett, A. R. & Wood, M. J. A., 1 Jan 2017, In : Human Molecular Genetics. 26, 22, p. 4441-4450 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Altered eigenvector centrality is related to local resting-state network functional connectivity in patients with longstanding type 1 diabetes mellitus

van Duinkerken, E., Schoonheim, M. M., Ijzerman, R. G., Moll, A. C., Landeira-Fernandez, J., Klein, M., Diamant, M., Snoek, F. J., Barkhof, F. & Wink, A. M., Jun 2017, In : Human Brain Mapping. p. 3623–3636

Research output: Contribution to journalArticleAcademicpeer-review

Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy

de Wit, N. M., Snkhchyan, H., den Hoedt, S., Wattimena, D., de Vos, R., Mulder, M. T., Walter, J., Martinez-Martinez, P., Hoozemans, J. J., Rozemuller, A. J. & de Vries, H. E., 2017, In : Journal of Alzheimer's Disease. 60, 3, p. 795-807 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination

Duncan, I. D., Bugiani, M., Radcliff, A. B., Moran, J. J., Lopez-Anido, C., Duong, P., August, B. K., Wolf, N. I., van der Knaap, M. S. & Svaren, J., 1 May 2017, In : Annals of Neurology. 81, 5, p. 690-702 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

An empirical Bayes approach to network recovery using external knowledge

Kpogbezan, G. B., van der Vaart, A. W., van Wieringen, W. N., Leday, G. G. R. & van de Wiel, M. A., 1 Sep 2017, In : Biometrical Journal. 59, 5, p. 932-947 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

An epigenome-wide association study meta-analysis of educational attainment

Karlsson Linnér, R., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davies, N. M., Watanabe, K., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S., Lahti, J., McRae, A. F., Mandaviya, P. R. & 51 others, Seppälä, I., Wang, Y., Baglietto, L., Binder, E. B., Harris, S. E., Hodge, A. M., Horvath, S., Hurme, M., Johannesson, M., Latvala, A., Mather, K. A., Medland, S. E., Metspalu, A., Milani, L., Milne, R. L., Pattie, A., Pedersen, N. L., Peters, A., Polidoro, S., Räikkönen, K., Severi, G., Starr, J. M., Stolk, L., Waldenberger, M., Eriksson, J. G., Esko, T., Franke, L., Gieger, C., Giles, G. G., Hägg, S., Jousilahti, P., Kaprio, J., Kähönen, M., Lehtimäki, T., Martin, N. G., Van Meurs, J. B. C., Ollikainen, M., Perola, M., Posthuma, D., Raitakari, O. T., Sachdev, P. S., Taskesen, E., Uitterlinden, A. G., Vineis, P., Wijmenga, C., Wright, M. J., Relton, C., Davey Smith, G., Deary, I. J., Koellinger, P. D. & Benjamin, D. J., 1 Dec 2017, In : Molecular Psychiatry. 22, 12, p. 1680-1690 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis

Sudre, C. H., Cardoso, M. J., Frost, C., Barnes, J., Barkhof, F., Fox, N., Ourselin, S. & Alzheimer's Disease Neuroimaging Initiative, May 2017, In : Neurobiology of Aging. 53, p. 67-75 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Apolipoprotein E epsilon 4 affects cognition, but not brain structure and functioning in patients with longstanding type 1 diabetes

van Duinkerken, E., Klein, M., Mograbi, D. C., Barkhof, F., Moll, A. C., Diamant, M., Snoek, F. J., Snoek, F. J. & IJzerman, R. G., Sep 2017, In : Diabetologia. 60, p. S580-S580

Research output: Contribution to journalMeeting AbstractAcademic