Amsterdam Neuroscience - Cellular and Molecular Mechanisms

Research Output

2001

Decreased smooth muscle cell/extracellular matrix ratio of media of femoral artery in patients with atherosclerosis and hyperhomocysteinemia

Vermeulen, E. G., Niessen, H. W., Bogels, M., Stehouwer, C. D., Rauwerda, J. A. & van Hinsbergh, V. W., Apr 2001, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 21, 4, p. 573-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Establishment of microglial cell cultures derived from postmortem human adult brain tissue: Immunophenotypical and functional characterization

De Groot, CJA., Hulshof, S., Hoozemans, JJM. & Veerhuis, R., 1 Jul 2001, In : MICROSCOPY RESEARCH AND TECHNIQUE. 54, 1, p. 34-39

Research output: Contribution to journalArticleAcademicpeer-review

Frequent monitoring of Epstein-Barr virus DNA load in unfractionated whole blood is essential for early detection of posttransplant lymphoproliferative disease in high-risk patients

Stevens, S. J., Verschuuren, E. A., Pronk, I., van Der Bij, W., Harmsen, M. C., The, T. H., Meijer, C. J., van Den Brule, A. J. & Middeldorp, J. M., 1 Mar 2001, In : Blood. 97, 5, p. 1165-71 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Frequent monitoring of Epstein-Barr virus DNA load in unfractionated whole blood is essential for early detection of post-transplant lymphoproliferative disease in lung transplant patients

Verschuuren, E. A., Stevens, S., Pronk, I., Van Der Bij, W., Harmsen, M. C., The, T. H., Meijer, C. J., Van Den Brule, A. J. & Middeldorp, J. M., Feb 2001, In : Journal of Heart and Lung Transplantation. 20, 2, p. 199-200 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Functional CD4(+) and CD8(+) T-cell responses induced by autologous mitomycin C treated Epstein-Barr virus transformed lymphoblastoid cell lines

Meij, P., Bloemena, E., Palmen, N., Brink, A., Vervoort, M. B., Meijer, C. J. & Middeldorp, J. M., 25 Feb 2001, In : Cellular Immunology. 208, 1, p. 25-33 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Functional MRI of visual cortex in sedated 18 month-old infants with or without periventricular leukomalacia

Sie, L. T. L., Rombouts, S. A. R. B., Valk, J., Hart, A. A. M., Scheltens, P. & Van Der Knaap, M. S., 26 Jul 2001, In : Developmental Medicine and Child Neurology. 43, 7, p. 486-490 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hemorragische cerebrates bij een neonatale Bacillus cereus infectie.

Vermeulen, R. J., van Elburg, RM., van der Zwet, W. C., Tutu-van Furth, AM., van der Knaap, MS. & Fetter, WPF., 2001, In : Nederlands Tijdschrift voor Geneeskunde. p. 2198

Research output: Contribution to journalArticleAcademicpeer-review

Immunological aspects of Alzheimer's disease - Therapeutic implications

Hoozemans, JJM., Rozemuller, AJM., Veerhuis, R. & Eikelenboom, P., 2001, In : BIODRUGS. 15, 5, p. 325-337

Research output: Contribution to journalArticleAcademicpeer-review

Improved interobserver agreement for visual detection of active T2 lesions on serial MR scans in multiple sclerosis using image registration

Tan, I. L., Van Schijndel, R. A., Fazekas, F., Filippi, M., Freitag, P., Miller, D. H., Yousry, T. A., Pouwels, P. J. W., Adèr, H. J., Quist, M. J. & Barkhof, F., 1 Jan 2001, In : Journal of Neural Transmission. 108, 8-9, p. 789-794 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vivo and in vitro NMR spectroscopy reveal a putative novel inborn error involving polyol metabolism

Moolenaar, S. H., Van Der Knaap, M. S., Engelke, U. F. H., Pouwels, P. J. W., Janssen-Zijlstra, F. S. M., Verhoeven, N. M., Jakobs, C. & Wevers, R. A., 23 Jun 2001, In : NMR in Biomedicine. 14, 3, p. 167-176 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Is Epstein-Barr virus present in the CNS of patients with MS?

Morré, S. A., van Beek, J., De Groot, C. J., Killestein, J., Meijer, C. J., Polman, C. H., van der Valk, P., Middeldorp, J. M. & van Den Brule, A. J., 13 Mar 2001, In : Neurology. 56, 5, p. 692

Research output: Contribution to journalArticleAcademicpeer-review

Magnetization transfer histogram parameters reflect all dimensions of MS pathology, including atrophy

Kalkers, N. F., Hintzen, R. Q., Van Waesberghe, J. H. T. M., Lazeron, R. H. C., Van Schijndel, R. A., Adèr, H. J., Polman, C. H. & Barkhof, F., 1 Mar 2001, In : Journal of the Neurological Sciences. 184, 2, p. 155-162 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Optimizing the association between disability and biological markers in MS

Kalkers, N. F., Bergers, E., Castelijns, J. A., Van Walderveen, M. A. A., Bot, J. C. J., Adèr, H. J., Polman, C. H. & Barkhof, F., 9 Oct 2001, In : Neurology. 57, 7, p. 1253-1258 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Perivenous support reduces early changes in human vein grafts: studies in whole blood perfused human vein segments

Stooker, W., Niessen, H. W., Baidoshvili, A., Wildevuur, W. R., Van Hinsbergh, V. W., Fritz, J., Wildevuur, C. R. & Eijsman, L., Feb 2001, In : Journal of Thoracic and Cardiovascular Surgery. 121, 2, p. 290-7 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Post-mortem high-resolution MRI of the spinal cord in multiple sclerosis: A correlative study with conventional MRI, histopathology and clinical phenotype

Lycklama À Nijeholt, G. J., Bergers, E., Kamphorst, W., Bot, J., Nicolay, K., Castelijns, J. A., Van Waesberghe, J. H. T. M., Ravid, R., Polman, C. H. & Barkhof, F., 30 Jan 2001, In : Brain. 124, 1, p. 154-166 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Raloxifene affects brain activation patterns in postmenopausal women during visual encoding

Neele, S. J. M., Rombouts, S. A. R. B., Bierlaagh, M. A., Barkhof, F., Scheltens, P. & Netelenbos, J. C., 30 Apr 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 3, p. 1422-1424 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Role for complement as an intermediate between C-reactive protein and intercellular adhesion molecule-1 expression?

Lagrand, W. K., Niessen, H. W., Nijmeijer, R. & Hack, C. E., 28 Aug 2001, In : Circulation. 104, 9, p. E46

Research output: Contribution to journalArticleAcademicpeer-review

Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors

Heideman, D. A., Snijders, P. J., Craanen, M. E., Bloemena, E., Meijer, C. J., Meuwissen, S. G., van Beusechem, V. W., Pinedo, H. M., Curiel, D. T., Haisma, H. J. & Gerritsen, W. R., May 2001, In : Cancer Gene Therapy. 8, 5, p. 342-51 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sporadic Creutzfeldt-Jakob disease in a young Dutch valine homozygote: Atypical molecular phenotype

Head, M. W., Tissingh, G., Uitdehaag, B. M. J., Barkhof, F., Bunn, T. J. R., Ironside, J. W., Kamphorst, W. & Scheltens, P., 22 Aug 2001, In : Annals of Neurology. 50, 2, p. 258-261 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line

Steenbergen, R. D. M., Kramer, D., Meijer, C. J. L. M., Walboomers, J. M. M., Trott, D. A., Cuthbert, A. P., Newbold, R. F., Overkamp, W. J. I., Zdzienicka, M. Z. & Snijders, P. J. F., 6 Jun 2001, In : Journal of the National Cancer Institute. 93, 11, p. 865-872 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2000

All infiltrating T-lymphocytes in Hodgkin's disease express immunohistochemically detectable T-cell receptor zeta-chains in situ

Dukers, D. F., Oudejans, J. J., Jaspars, E. H., Gras, M., Vos, W., Middeldorp, J. M., Meijer, C. J. & Bloemena, E., Jun 2000, In : Histopathology. 36, 6, p. 544-50 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Apolipoprotein H, a new mediator in the inflammatory changes ensuring in jeopardised human myocardium

Niessen, H. W., Lagrand, W. K., Rensink, H. J., Meijer, C. J., Aarden, L., Hack, C. E. & Visser, C., Nov 2000, In : Journal of Clinical Pathology. 53, 11, p. 863-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Autocrine transforming growth factor-β growth pathway in murine osteosarcoma cell lines associated with inability to affect phosphorylation of retinoblastoma protein

Navid, F., Letterio, J. J., Yeung, C. L., Pegtel, M. & Helman, L. J., 1 Jan 2000, In : Sarcoma. 4, 3, p. 93-102 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Bioreactor-scale production and one-step purification of Epstein-Barr nuclear antigen 1 expressed in baculovirus-infected insect cells

Meij, P., Vervoort, M. B., de Gooijer, K., Bloemena, E., Meijer, C. J. & Middeldorp, J. M., Nov 2000, In : Protein expression and purification. 20, 2, p. 324-33 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of a conventional cardiac-triggered dual spin-echo and a fast STIR sequence in detection of spinal cord lesion in multiples sclerosis

Bot, J. C. J., Barkhof, F., Lycklama À Nijeholt, G. J., Bergers, E., Polman, C. H., Adèr, H. J. & Castelijns, J. A., 8 Jun 2000, In : European Radiology. 10, 5, p. 753-758 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

C-reactive protein and cardiovascular disease: linked by complement?

Lagrand, W. K., Visser, C. A., Hack, C. E., Niessen, H. W. & Nijmeijer, R., Oct 2000, In : Nephrology, Dialysis, Transplantation. 15, 10, p. 1709-10 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Direct immunosuppressive effects of EBV-encoded latent membrane protein 1

Dukers, D. F., Meij, P., Vervoort, M. B., Vos, W., Scheper, R. J., Meijer, C. J., Bloemena, E. & Middeldorp, J. M., 15 Jul 2000, In : Journal of Immunology. 165, 2, p. 663-70 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Functional MR imaging in Alzheimer's disease during memory encoding

Rombouts, S. A. R. B., Barkhof, F., Veltman, D. J., Machielsen, W. C. M., Witter, M. P., Bierlaagh, M. A., Lazeron, R. H. C., Valk, J. & Scheltens, P., 29 Nov 2000, In : American Journal of Neuroradiology. 21, 10, p. 1869-1875 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Functional segregation of memory for objects and locations

Machielsen, W. C. M., Rombouts, S. A. R. B., Barkhof, F., Scheltens, P. & Witter, M. P., 1 Dec 2000, In : NeuroImage. 11, 5 PART II

Research output: Contribution to journalArticleAcademicpeer-review

Humaan papillomavirus en het ontstaan van baarmoederhalskanker: Concept van carcinogenese

Translated title of the contribution: Human papilloma virus and development of cervical carcinoma: The concept of carcinogenesisWalboomers, J. M. M., Meijer, C. J. L. M., Steenbergen, R. D. M., Van Duin, M., Helmerhorst, T. J. M. & Snijders, P. J. F., 26 Aug 2000, In : Nederlands Tijdschrift voor Geneeskunde. 144, 35, p. 1671-1674 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes in women with cervical neoplasia

Bontkes, H. J., de Gruijl, T. D., van den Muysenberg, A. J. C., Verheijen, R. H. M., Stukart, M. J., Meijer, C. J. L. M., Scheper, R. J., Stacey, S. N., Duggan-Keen, M. F., Stern, P. L., Man, S., Borysiewicz, L. K. & Walboomers, J. M. M., 18 Sep 2000, In : International Journal of Cancer. 88, 1, p. 92-98 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mental retardation and behavioral problems as presenting signs of a creatine synthesis defect

Van Der Knaap, M. S., Verhoeven, N. M., Maaswinkel-Mooij, P., Pouwels, P. J. W., Onkenhout, W., Peeters, E. A. J., Stöckler-Ipsiroglu, S. & Jakobs, C., 19 Apr 2000, In : Annals of Neurology. 47, 4, p. 540-543 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microorganisms in the aetiology of atherosclerosis

Morré, S. A., Stooker, W., Lagrand, W. K., van den Brule, A. J. & Niessen, H. W., Sep 2000, In : Journal of Clinical Pathology. 53, 9, p. 647-54 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

MR venography of multiple sclerosis

Tan, I. L., Van Schijndel, R. A., Pouwels, P. J. W., Van Walderveen, M. A. A., Reichenbach, J. R., Manoliu, R. A. & Barkhof, F., 30 Jun 2000, In : American Journal of Neuroradiology. 21, 6, p. 1039-1042 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuroinflammation and Alzheimer disease: Clinical and therapeutic implications

Eikelenboom, P., Rozemuller, AJM., Hoozemans, JJM., Veerhuis, R. & Van Gool, WA., 2000, In : Alzheimer Disease and Associated Disorders. 14, p. S54-S61

Research output: Contribution to journalArticleAcademicpeer-review

Production monitoring and purification of EBV encoded latent membrane protein 1 expressed and secreted by recombinant baculovirus infected insect cells

Meij, P., Vervoort, M. B., Meijer, C. J., Bloemena, E. & Middeldorp, J. M., Nov 2000, In : Journal of Virological Methods. 90, 2, p. 193-204 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quantitative immunohistochemical analysis of cytokine profiles in Epstein-Barr virus-positive and -negative cases of Hodgkin's disease

Dukers, D. F., Jaspars, L. H., Vos, W., Oudejans, J. J., Hayes, D., Cillessen, S., Middeldorp, J. M. & Meijer, C. J., Feb 2000, In : Journal of Pathology. 190, 2, p. 143-9 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Synaptic assembly of the brain in the absence of neurotransmitter secretion

Verhage, M., Maia, A. S., Plomp, J. J., Brussaard, A. B., Heeroma, J. H., Vermeer, H., Toonen, R. F., Hammer, R. E., van den Berg, T. K., Missler, M., Geuze, H. J. & Südhof, T. C., 4 Feb 2000, In : Science. 287, 5454, p. 864-9 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Unbiased whole-brain analysis of gray matter loss in Alzheimer's disease

Rombouts, S. A. R. B., Barkhof, F., Witter, M. P. & Scheltens, P., 19 May 2000, In : Neuroscience Letters. 285, 3, p. 231-233 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Unique transcription pattern of Epstein-Barr virus (EBV) in EBV-carrying gastric adenocarcinomas: expression of the transforming BARF1 gene

zur Hausen, A., Brink, A. A., Craanen, M. E., Middeldorp, J. M., Meijer, C. J. & van den Brule, A. J., 15 May 2000, In : Cancer Research. 60, 10, p. 2745-8 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Visualizing brain activation during planning: The Tower of London test adapted for functional MR imaging

Lazeron, R. H. C., Rombouts, S. A. R. B., Machielsen, W. C. M., Scheltens, P., Witter, M. P., Uylings, H. B. M. & Barkhof, F., 2 Oct 2000, In : American Journal of Neuroradiology. 21, 8, p. 1407-1414 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1999

C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?

Lagrand, W. K., Visser, C. A., Hermens, W. T., Niessen, H. W., Verheugt, F. W., Wolbink, G. J. & Hack, C. E., 6 Jul 1999, In : Circulation. 100, 1, p. 96-102 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Decreased interleukin-10 and increased interleukin- 12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis

Van Boxel-Dezaire, A. H. H., Hoff, S. C. J., Van Oosten, B. W., Verweij, C. L., Dräger, A. M., Adèr, H. J., Van Houwelingen, J. C., Barkhof, F., Polman, C. H. & Nagelkerken, L., 15 Jun 1999, In : Annals of Neurology. 45, 6, p. 695-703 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of hypointense lesions on T1-weighted spin-echo magnetic resonance images in multiple sclerosis: Relation to inflammatory activity

Van Walderveen, M. A. A., Truyen, L., Van Oosten, B. W., Castelijns, J. A., Lycklama À Nijeholt, G. J., Van Waesberghe, J. H. T. M., Polman, C. & Barkhof, F., 1 Jan 1999, In : Archives of Neurology. 56, 3, p. 345-351 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Differences in cytokine mRNA profiles between premalignant and malignant lesions of the uterine cervix

De Gruijl, T. D., Bontkes, H. J., Van den Muysenberg, A. J. C., Van Oostveen, J. W., Stukart, M. J., Verheijen, R. H. M., Van der Vange, N., Snijders, P. J. F., Meijer, C. J. L. M., Walboomers, J. M. M. & Scheper, R. J., 1 Jan 1999, In : European Journal of Cancer. 35, 3, p. 490-497 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression of CD3-ζ on T-cells in primary cervical carcinoma and in metastasis-positive and -negative pelvic lymph nodes

De Gruijl, T. D., Bontkes, H. J., Peccatori, F., Gallee, M. P. W., Helmerhorst, T. J. M., Verheijen, R. H. M., Aarbiou, J., Mulder, W. M. C., Walboomers, J. M. M., Meijer, C. J. L. M., Van De Vange, N. & Scheper, R. J., 28 Feb 1999, In : British Journal of Cancer. 79, 7-8, p. 1127-1132 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression of Epstein-Barr virus (EBV) transcripts encoding homologues to important human proteins in diverse EBV associated diseases

Hayes, D. P., Brink, A. A., Vervoort, M. B., Middeldorp, J. M., Meijer, C. J. & van den Brule, A. J., Apr 1999, In : Modern Pathology. 52, 2, p. 97-103 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Human papillomavirus type 16 E2-specific T-helper lymphocyte responses in patients with cervical intraepithelial neoplasia

Bontkes, H. J., De Gruijl, T. D., Bijl, A., Verheijen, R. H. M., Meijer, C. J. L. M., Scheper, R. J., Stern, P. L., Burns, J. E., Maitland, N. J. & Walboomers, J. M. M., 1 Jan 1999, In : Journal of General Virology. 80, 9, p. 2453-2459 7 p.

Research output: Contribution to journalArticleAcademicpeer-review