Amsterdam Neuroscience - Cellular and Molecular Mechanisms

Research Output

Childhood white matter disorders: much more than just diseases of myelin

Bugiani, M. & van der Knaap, M. S., 1 Sep 2017, In : Acta Neuropathologica. 134, 3, p. 329-330 2 p.

Research output: Contribution to journalEditorialAcademic

Choosing drug therapy for multiple sclerosis. An update

Van Oosten, B. W., Truyen, L., Barkhof, F. & Polman, C. H., 7 Nov 1998, In : Drugs. 56, 4, p. 555-569 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression

Heine, V. M., Zareno, J., Maslam, S., Joëls, M. & Lucassen, P. J., Mar 2005, In : European Journal of Neuroscience. 21, 5, p. 1304-14 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis

Elliott, C., Belachew, S., Wolinsky, J. S., Hauser, S. L., Kappos, L., Barkhof, F., Bernasconi, C., Fecker, J., Model, F., Wei, W. & Arnold, D. L., 1 Sep 2019, In : Brain. 142, 9, p. 2787-2799 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Circulating RNAs as biomarkers in Epstein-Barr virus-associated nasopharyngeal carcinoma

Ramayanti, O., Verkuijlen, S. A. W. M., Beckers, L., Meijer, J., Martorelli, D., Scheepbouwer, C., Hackenberg, M., Brakenhoff, R. H., Adham, M., Koppers-Lalic, D., Pegtel, D. M. & Middeldorp, J. M., 2016, In : Journal of Extracellular Vesicles. 5, p. 14 1 p.

Research output: Contribution to journalArticleAcademic

Circulating tumor DNA analysis: clinical implications for colorectal cancer patients. A systematic review

Bach, S., Sluiter, N. R., Beagan, J., Mekke, J. M., Ket, J. C. F., van Grieken, N. C. T., Steenbergen, R. D. M., Ylstra, B., Kazemier, G. & Tuynman, J. B., 19 Jun 2019, In : JNCI Cancer Spectrum. 3, 3, pkz042.

Research output: Contribution to journalArticleAcademicpeer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Glanville, K. P., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J. & 33 others, de Geus, E. J. C., Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Magnusson, P. K., McGuffin, P., McIntosh, A. M., Milaneschi, Y., Mors, O., Mostafavi, S., Müller-Myhsok, B., Pedersen, N. L., Penninx, B. W. J. H., Potash, J. B., Preisig, M., Ripke, S., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Weissman, M. M. & O'Reilly, P. F., 5 Aug 2019, In : Biological Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Clinical, biochemical, and molecular overview of transaldolase deficiency and evaluation of the endocrine function: update of 34 patients

Williams, M., Valayannopoulos, V., Altassan, R., Chung, W. K., Heijboer, A. C., Keng, W. T., Lapatto, R., McClean, P., Mulder, M. F., Tylki-Szymańska, A., Walenkamp, M-J. E., Alfadhel, M., Alakeel, H., Salomons, G. S., Eyaid, W. & Wamelink, M. M. C., 1 Jan 2019, In : Journal of Inherited Metabolic Disease. 42, 1, p. 147-158 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Clinical, neuroradiological, and biochemical features of SLC35A2-CDG patients

Vals, M-A., Ashikov, A., Ilves, P., Loorits, D., Zeng, Q., Barone, R., Huijben, K., Sykut-Cegielska, J., Diogo, L., Elias, A. F., Greenwood, R. S., Grunewald, S., van Hasselt, P. M., van de Kamp, J. M., Mancini, G., Okninska, A., Pajusalu, S., Rudd, P. M., Rustad, C. F., Salvarinova, R. & 5 others, de Vries, B. B. A., Wolf, N. I., Lefeber, D. J., Õunap, K. & EPGEN Study, 1 May 2019, In : Journal of Inherited Metabolic Disease. 42, 3, p. 553-564 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Clinically Distinct Phenotypes of Canavan Disease Correlate with Residual Aspartoacylase Enzyme Activity

Mendes, M. I., Smith, D. E. C., Pop, A., Lennertz, P., Fernandez Ojeda, M. R., Kanhai, W. A., van Dooren, S. J. M., Anikster, Y., Barić, I., Boelen, C., Campistol, J., de Boer, L., Kariminejad, A., Kayserili, H., Roubertie, A., Verbruggen, K. T., Vianey-Saban, C., Williams, M. & Salomons, G. S., 1 May 2017, In : Human Mutation. 38, 5, p. 524-531 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS

Rocca, M. A., Valsasina, P., Meani, A., Gobbi, C., Zecca, C., Rovira, À., Montalban, X., Kearney, H., Ciccarelli, O., Matthews, L., Palace, J., Gallo, A., Bisecco, A., Gass, A., Eisele, P., Lukas, C., Bellenberg, B., Barkhof, F., Vrenken, H., Preziosa, P. & 3 others, Comi, G., Filippi, M. & MAGNIMS Study Group, 12 Nov 2019, In : Neurology. 93, 20, p. e1852-e1866

Research output: Contribution to journalArticleAcademicpeer-review

Clinical presentation and management of dyskinetic cerebral palsy

Monbaliu, E., Himmelmann, K., Lin, J-P., Ortibus, E., Bonouvrié, L., Feys, H., Vermeulen, R. J. & Dan, B., Sep 2017, In : Lancet Neurology. 16, 9, p. 741-749 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment

Ferro, D. A., van den Brink, H., Exalto, L. G., Boomsma, J. M. F., Barkhof, F., Prins, N. D., van der Flier, W. M., Biessels, G. J. & TRACE-VCI study group, 2 Apr 2019, In : Neurology. 92, 14, p. e1558-e1566

Research output: Contribution to journalArticleAcademicpeer-review

Clinical utility of bone markers in various diseases

Vlot, M. C., den Heijer, M., de Jongh, R. T., Vervloet, M. G., Lems, W. F., de Jonge, R., Obermayer-Pietsch, B. & Heijboer, A. C., 1 Sep 2018, In : Bone. 114, p. 215-225 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia

Meeter, L. H. H., Steketee, R. M. E., Salkovic, D., Vos, M. E., Grossman, M., McMillan, C. T., Irwin, D. J., Boxer, A. L., Rojas, J. C., Olney, N. T., Karydas, A., Miller, B. L., Pijnenburg, Y. A. L., Barkhof, F., Sánchez-Valle, R., Lladó, A., Borrego-Ecija, S., Diehl-Schmid, J., Grimmer, T., Goldhardt, O. & 27 others, Santillo, A. F., Hansson, O., Vestberg, S., Borroni, B., Padovani, A., Galimberti, D., Scarpini, E., Rohrer, J. D., Woollacott, I. O. C., Synofzik, M., Wilke, C., de Mendonca, A., Vandenberghe, R., Benussi, L., Ghidoni, R., Binetti, G., Niessen, W. J., Papma, J. M., Seelaar, H., Jiskoot, L. C., de Jong, F. J., Donker Kaat, L., del Campo, M., Teunissen, C. E., Bron, E. E., van den Berg, E. & van Swieten, J. C., 1 Sep 2019, In : Journal of Neurology, Neurosurgery and Psychiatry. 90, 9, p. 997-1004 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum

Meeter, L. H. H., Vijverberg, E. G., Del Campo, M., Rozemuller, A. J. M., Donker Kaat, L., de Jong, F. J., van der Flier, W. M., Teunissen, C. E., van Swieten, J. C. & Pijnenburg, Y. A. L., 3 Apr 2018, In : Neurology. 90, 14, p. e1231-e1239

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Clinico-radiological dissociation of disease activity in MS patients: frequency and clinical relevance

van Faals, N. L., Dekker, I., Balk, L. J., Moraal, B., Barkhof, F., Uitdehaag, B. M. J., Killestein, J. & Wattjes, M. P., 20 Jun 2020, In : Journal of Neurology.

Research output: Contribution to journalArticleAcademicpeer-review

COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART-BRAIN AXIS: THE ROLE OF CEREBRAL BLOOD FLOW

Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H-P. H. P., Kappelle, J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A., Prins, N. D., Biessels, G. J., Barkhof, F. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P755-P756

Research output: Contribution to journalMeeting AbstractAcademic

Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship

van Loenhoud, A. C., van der Flier, W. M., Wink, A. M., Dicks, E., Groot, C., Twisk, J., Barkhof, F., Scheltens, P., Ossenkoppele, R. & Alzheimer's Disease Neuroimaging Initiative, 23 Jul 2019, In : Neurology. 93, 4, p. e334-e346

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Co-localization of cyclo-oxygenase 2 with cyclin D1 and cyclin E in pyramidal neurons in Alzheimer's disease temporal cortex

Hoozemans, JJM., Veerhuis, R., Bruckner, MK., Arendt, T., Rozemuller, AJM. & Eikelenboom, P., 2002, In : Neurobiology of Aging. 23, 1, p. S222-S222

Research output: Contribution to journalArticleAcademicpeer-review

Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer

Neerincx, M., Poel, D., Sie, D. L. S., van Grieken, N. C. T., Shankaraiah, R. C., van der Wolf-de Lijster, F. S. W., van Waesberghe, J-H. T. M., Burggraaf, J-D., Eijk, P. P., Verhoef, C., Ylstra, B., Meijer, G. A., van de Wiel, M. A., Buffart, T. E. & Verheul, H. M. W., 2018, In : PLoS ONE. 13, 8, p. e0201809

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population

Alemany, S., Jansen, P. R., Muetzel, R. L., Marques, N., el Marroun, H., Jaddoe, V. W. V., Polderman, T. J. C., Tiemeier, H., Posthuma, D. & White, T., 1 Jun 2019, In : Journal of the American Academy of Child and Adolescent Psychiatry. 58, 6, p. 600-607 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comorbid amyloid-β pathology affects clinical and imaging features in VCD

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, M. J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., 1 Feb 2020, In : Alzheimers & Dementia. 16, 2, p. 354-364 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

COMORBID AMYLOID-β PATHOLOGY AFFECTS NEUROPSYCHIATRIC, NEUROPSYCHOLOGICAL, AND IMAGING FEATURES IN VASCULAR COGNITIVE DISORDERS

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P888-P889

Research output: Contribution to journalMeeting AbstractAcademic

Comparative gene expression study and pathway analysis of the human iris- and the retinal pigment epithelium

Bennis, A., Ten Brink, J. B., Moerland, P. D., Heine, V. M. & Bergen, A. A., 1 Aug 2017, In : PLoS ONE. 12, 8, e0182983.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comparison of a conventional cardiac-triggered dual spin-echo and a fast STIR sequence in detection of spinal cord lesion in multiples sclerosis

Bot, J. C. J., Barkhof, F., Lycklama À Nijeholt, G. J., Bergers, E., Polman, C. H., Adèr, H. J. & Castelijns, J. A., 8 Jun 2000, In : European Radiology. 10, 5, p. 753-758 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of psychomotor outcome in patients with perinatal asphyxia with versus without therapeutic hypothermia at 4 years using the Ages and Stages Questionnaire screening tool

Zonnenberg, I. A., Koopman, C., van Schie, P. E. M., Vermeulen, R. J., Groenendaal, F. & van Weissenbruch, M. M., Jul 2016, In : European Journal of Paediatric Neurology. 20, 4, p. 545-548

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of time and frequency domain measures of RSA in ambulatory recordings

Goedhart, A. D., Van Der Sluis, S., Houtveen, J. H., Willemsen, G. & De Geus, E. J. C., Mar 2007, In : Psychophysiology. 44, 2, p. 203-215 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Competition and Homeostasis of Excitatory and Inhibitory Connectivity in the Adult Mouse Visual Cortex

Saiepour, M. H., Chakravarthy, S., Min, R. & Levelt, C. N., Oct 2015, In : Cerebral Cortex. 25, 10, p. 3713-22 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Complement c1-inhibitor expression in Alzheimer's disease

Veerhuis, R., Janssen, I., Hoozemans, JJM., De Groot, CJA., Hack, CE. & Eikelenboom, P., Sep 1998, In : Acta Neuropathologica. 96, 3, p. 287-296

Research output: Contribution to journalArticleAcademicpeer-review

Comprehensive analysis of GST-pi expression in B-cell lymphomas: Correlation with histological subtypes and survival

Thieblemont, C., Rolland, D., Baseggio, L., Felman, P., Gazzo, S., Callet-Bauchu, E., Traverse-Glehen, A., Houlgatte, R., Fu, K., Weisenburger, D., De Jong, D., Jaffe, E. S., Rosenwald, A., Ott, G., Coiffier, B. & Berger, F., Jul 2008, In : Leukemia and Lymphoma. 49, 7, p. 1403-6 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comprehensive molecular characterisation of HPV-induced transformation by longitudinal statistical modelling

Miok, V., 2018, 176 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University Amsterdam

Computer-assisted prediction of clinical progression in the earliest stages of AD

Rhodius-Meester, H. F. M., Liedes, H., Koikkalainen, J., Wolfsgruber, S., Coll-Padros, N., Kornhuber, J., Peters, O., Jessen, F., Kleineidam, L., Molinuevo, J. L., Rami, L., Teunissen, C. E., Barkhof, F., Sikkes, S. A. M., Wesselman, L. M. P., Slot, R. E. R., Verfaillie, S. C. J., Scheltens, P., Tijms, B. M., Lötjönen, J. & 1 others, van der Flier, W. M., 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 726-736

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Concordance of specific human papillomavirus types in sex partners is more prevalent than would be expected by chance and is associated with increased viral loads

Bleeker, M. C. G., Hogewoning, C. J. A., Berkhof, J., Voorhorst, F. J., Hesselink, A. T., van Diemen, P. M., van den Brule, A. J. C., Snijders, P. J. F. & Meijer, C. J. L. M., 1 Sep 2005, In : Clinical Infectious Diseases. 41, 5, p. 612-620 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

de Leeuw, C. A., Stringer, S., Dekkers, I. A., Heskes, T. & Posthuma, D., 2018, In : Nature Communications. 9, 1, 3768.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Condom use promotes regression of cervical intraepithelial neoplasia and clearance of human papillomavirus: a randomized clinical trial

Hogewoning, C. J. A., Bleeker, M. C. G., van den Brule, A. J. C., Voorhorst, F. J., Snijders, P. J. F., Berkhof, J., Westenend, P. J. & Meijer, C. J. L. M., 10 Dec 2003, In : International Journal of Cancer. 107, 5, p. 811-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Condom use promotes regression of human papillomavirus-associated penile lesions in male sexual partners of women with cervical intraepithelial neoplasia

Bleeker, M. C. G., Hogewoning, C. J. A., Voorhorst, F. J., van den Brule, A. J. C., Snijders, P. J. F., Starink, T. M., Berkhof, J. & Meijer, C. J. L. M., 10 Dec 2003, In : International Journal of Cancer. 107, 5, p. 804-10 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Confirmation of a Rare Genetic Leukoencephalopathy due to a Novel Bi-allelic Variant in RPIA

Kaur, P., Wamelink, M. M. C., van der Knaap, M. S., Girisha, K. M. & Shukla, A., 1 Aug 2019, In : European Journal of Medical Genetics. 62, 8, 103708.

Research output: Contribution to journalArticleAcademicpeer-review

Connecting heart and brain: vascular determinants of cognitive impairment and depressive symptoms

Leeuwis, AE., 2019, 240 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University Amsterdam

Open Access

Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer's disease

Chatterjee, M., Del Campo, M., Morrema, T. H. J., de Waal, M., van der Flier, W. M., Hoozemans, J. J. M. & Teunissen, C. E., 1 Jun 2018, In : Alzheimer's Research & Therapy. 10, 1, p. 52

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors

Golovko, T., Min, R., Lozovaya, N., Falconer, C., Yatsenko, N., Tsintsadze, T., Tsintsadze, V., Ledent, C., Harvey, R. J., Belelli, D., Lambert, J. J., Rozov, A. & Burnashev, N., Sep 2015, In : Cerebral Cortex. 25, 9, p. 2440-55 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD

Drakulic, D., Djurovic, S., Syed, Y. A., Trattaro, S., Caporale, N., Falk, A., Ofir, R., Heine, V. M., Chawner, S. J. R. A., Rodriguez-Moreno, A., van den Bree, M. B. M., Testa, G., Petrakis, S. & Harwood, A. J., 1 Jun 2020, In : Molecular autism. 11, 1, 1 p., 42.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Coronary artery calcification in middle-aged women with premature ovarian insufficiency

Gunning, M. N., Meun, C., van Rijn, B. B., Maas, A. H. E. M., Benschop, L., Franx, A., Boersma, E., Budde, R. P. J., Appelman, Y., Lambalk, C. B., Eijkemans, M. J. C., Velthuis, B. K., Laven, J. S. E., Fauser, B. C. J. M. & On behalf of the CREW-consortium, 1 Aug 2019, In : Clinical Endocrinology. 91, 2, p. 314-322

Research output: Contribution to journalArticleAcademicpeer-review

Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Verweij, F. J., Bebelman, M. P., Jimenez, C. R., Garcia-Vallejo, J. J., Janssen, H., Neefjes, J., Knol, J. C., de Goeij-de Haas, R., Piersma, S. R., Baglio, S. R., Verhage, M., Middeldorp, J. M., Zomer, A., van Rheenen, J., Coppolino, M. G., Hurbain, I., Raposo, G., Smit, M. J., Toonen, R. F. G., van Niel, G. & 1 others, Pegtel, D. M., 5 Mar 2018, In : Journal of Cell Biology. 217, 3, p. 1157

Research output: Contribution to journalErratumAcademicpeer-review

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (Molecular Psychiatry, (2020), 10.1038/s41380-019-0546-6)

Coleman, J. R. I. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalErratumAcademicpeer-review

Open Access

Correction: Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction

Hollander, M. R., de Waard, G. A., Konijnenberg, L. S. F., Meijer-van Putten, R. M. E., van den Brom, C. E., Paauw, N., de Vries, H. E., van de Ven, P. M., Aman, J., Van Nieuw Amerongen, G. P., Hordijk, P. L., Niessen, H. W. M., Horrevoets, A. J. G. & Van Royen, N., 2016, In : PLoS ONE. 11, 11, p. e0166809

Research output: Contribution to journalArticleAcademicpeer-review

Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence (Molecular Psychiatry, (2019), 10.1038/s41380-018-0332-x)

Smeland, O. B., Bahrami, S., Frei, O., Shadrin, A., O’Connell, K., Savage, J., Watanabe, K., Krull, F., Bettella, F., Steen, N. E., Ueland, T., Posthuma, D., Djurovic, S., Dale, A. M. & Andreassen, O. A., 1 Jan 2019, In : Molecular Psychiatry.

Research output: Contribution to journalErratumAcademicpeer-review

Open Access
Open Access