Amsterdam Neuroscience - Cellular and Molecular Mechanisms

Research Output

Genetic correlation of antisocial behaviour with alcohol, nicotine, and cannabis use

Tielbeek, J. J., Vink, J. M., Polderman, T. J. C., Popma, A., Posthuma, D. & Verweij, K. J. H., 2018, In : Drug and Alcohol Dependence. 187, p. 296-299

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic defects disrupting glial ion and water homeostasis in the brain

Min, R. & van der Knaap, M. S., May 2018, In : Brain Pathology. 28, 3, p. 372-387 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic defects in mtDNA-encoded protein translation cause pediatric, mitochondrial cardiomyopathy with early-onset brain disease

Kamps, R., Szklarczyk, R., Theunissen, T. E., Hellebrekers, D. M. E. I., Sallevelt, S. C. E. H., Boesten, I. B., de Koning, B., van den Bosch, B. J., Salomons, G. S., Simas-Mendes, M., Verdijk, R., Schoonderwoerd, K., de Coo, I. F. M., Vanoevelen, J. M. & Smeets, H. J. M., 2018, In : European Journal of Human Genetics. 26, 4, p. 537-551

Research output: Contribution to journalArticleAcademicpeer-review

GENETIC META-ANALYSIS IDENTIFIES 9 NOVEL LOCI AND FUNCTIONAL PATHWAYS FOR ALZHEIMER'S DISEASE RISK

Posthuma, D., Jansen, I., Savage, J., Watanabe, K., Bryois, J., Williams, D. M., van der Flier, W. M., Dobson, R., Davis, L. K., Stefansson, H., Stefansson, K., Pedersen, N. L., Ripke, S. & Andreassen, O. A., 2019, In : European Neuropsychopharmacology. 29, p. 1074-1074

Research output: Contribution to journalMeeting AbstractAcademic

Genetic screening in early-onset Alzheimer's disease identified three novel presenilin mutations

Wong, T. H., Seelaar, H., Melhem, S., Rozemuller, A. J. M. & van Swieten, J. C., 29 Jan 2019, In : Neurobiology of Aging.

Research output: Contribution to journalArticleAcademicpeer-review

Genetics of intellectual ability and disability: The importance of common variants and rare syndromes illustrated by studies of SNAP25 and AUTS2

Beunders, G., 2018, 160 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University Amsterdam

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

the 23andMe Research Team, 1 Mar 2019, In : Nature Genetics. 51, 3, p. 394-403 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence

Smeland, O. B., Bahrami, S., Frei, O., Shadrin, A., O’Connell, K., Savage, J., Watanabe, K., Krull, F., Bettella, F., Steen, N. E., Ueland, T., Posthuma, D., Djurovic, S., Dale, A. M. & Andreassen, O. A., 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N. & 196 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L., Caplin, A. H. & 37 others, Chen, C-Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Jansen, R., Penninx, B., Peyrot, W. J., Evans, D. M., Milaneschi, Y., Posthuma, D., 23and Me Research Team, Schunk, D., Stein, M. B., Svento, R., Tiemeier, H., Timmers, P. R. H. J., Turley, P., Ursano, R. J., Wagner, G. G., Wilson, J. F., Gratten, J., Lee, J. J., Cesarini, D., Benjamin, D. J., Koellinger, P. D. & Beauchamp, J. P., 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits

Hammerschlag, A. R., Stringer, S., De Leeuw, C. A., Sniekers, S., Taskesen, E., Watanabe, K., Blanken, T. F., Dekker, K., Te Lindert, B. H. W., Wassing, R., Jonsdottir, I., Thorleifsson, G., Stefansson, H., Gislason, T., Berger, K., Schormair, B., Wellmann, J., Winkelmann, J., Stefansson, K., Oexle, K. & 2 others, Van Someren, E. J. W. & Posthuma, D., 1 Nov 2017, In : Nature Genetics. 49, 11, p. 1584-1592 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

Savage, J. E., Jansen, P. R., Stringer, S., Watanabe, K., Bryois, J., De Leeuw, C. A., Nagel, M., Awasthi, S., Barr, P. B., Coleman, J. R. I., Grasby, K. L., Hammerschlag, A. R., Kaminski, J. A., Karlsson, R., Krapohl, E., Lam, M., Nygaard, M., Reynolds, C. A., Trampush, J. W., Young, H. & 97 others, Zabaneh, D., Hägg, S., Hansell, N. K., Karlsson, I. K., Linnarsson, S., Montgomery, G. W., Muñoz-Manchado, A. B., Quinlan, E. B., Schumann, G., Skene, N. G., Webb, B. T., White, T., Arking, D. E., Avramopoulos, D., Bilder, R. M., Bitsios, P., Burdick, K. E., Cannon, T. D., Chiba-Falek, O., Christoforou, A., Cirulli, E. T., Congdon, E., Corvin, A., Davies, G., Deary, I. J., Derosse, P., Dickinson, D., Djurovic, S., Donohoe, G., Conley, E. D., Eriksson, J. G., Espeseth, T., Freimer, N. A., Giakoumaki, S., Giegling, I., Gill, M., Glahn, D. C., Hariri, A. R., Hatzimanolis, A., Keller, M. C., Knowles, E., Koltai, D., Konte, B., Lahti, J., Le Hellard, S., Lencz, T., Liewald, D. C., London, E., Lundervold, A. J., Malhotra, A. K., Melle, I., Morris, D., Need, A. C., Ollier, W., Palotie, A., Payton, A., Pendleton, N., Poldrack, R. A., Räikkönen, K., Reinvang, I., Roussos, P., Rujescu, D., Sabb, F. W., Scult, M. A., Smeland, O. B., Smyrnis, N., Starr, J. M., Steen, V. M., Stefanis, N. C., Straub, R. E., Sundet, K., Tiemeier, H., Voineskos, A. N., Weinberger, D. R., Widen, E., Yu, J., Abecasis, G., Andreassen, O. A., Breen, G., Christiansen, L., Debrabant, B., Dick, D. M., Heinz, A., Hjerling-Leffler, J., Ikram, M. A., Kendler, K. S., Martin, N. G., Medland, S. E., Pedersen, N. L., Plomin, R., Polderman, T. J. C., Ripke, S., Van Der Sluis, S., Sullivan, P. F., Vrieze, S. I., Wright, M. J. & Posthuma, D., 1 Jul 2018, In : Nature Genetics. 50, 7, p. 912-919 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association meta- A nalysis of 78,308 individuals identifies new loci and genes influencing human intelligence

Sniekers, S., Stringer, S., Watanabe, K., Jansen, P. R., Coleman, J. R. I., Krapohl, E., Taskesen, E., Hammerschlag, A. R., Okbay, A., Zabaneh, D., Amin, N., Breen, G., Cesarini, D., Chabris, C. F., Iacono, W. G., Ikram, M. A., Johannesson, M., Koellinger, P., Lee, J. J., Magnusson, P. K. E. & 10 others, McGue, M., Miller, M. B., Ollier, W. E. R., Payton, A., Pendleton, N., Plomin, R., Rietveld, C. A., Tiemeier, H., Van Duijn, C. M. & Posthuma, D., 1 Jul 2017, In : Nature Genetics. 49, 7, p. 1107-1112 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association study of the sensitivity to environmental stress and adversity neuroticism cluster

Nagel, M., Speed, D., van der Sluis, S. & Østergaard, S. D., 1 May 2020, In : Acta Psychiatrica Scandinavica. 141, 5, p. 476-478 3 p.

Research output: Contribution to journalLetterAcademicpeer-review

Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus

Smeets, S. J., Braakhuis, B. J. M., Abbas, S., Snijders, P. J. F., Ylstra, B., Van De Wiel, M. A., Meijer, G. A., Leemans, C. R. & Brakenhoff, R. H., 20 Apr 2006, In : Oncogene. 25, 17, p. 2558-2564 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 206 others, Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Howard, D. M., Ising, M., Jansen, R., Jones, I., Jones, L. A., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M., O’Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C., Breen, G. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23 Jan 2020, In : Molecular Psychiatry. 25, 7, 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland, 2018, In : PLoS ONE. 13, 12, e0209160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer

Snoek, B. C., Verlaat, W., Babion, I., Novianti, P. W., van de Wiel, M. A., Wilting, S. M., van Trommel, N. E., Bleeker, M. C. G., Massuger, L. F. A. G., Melchers, W. J. G., Sie, D., Heideman, D. A. M., Snijders, P. J. F., Meijer, C. J. L. M. & Steenbergen, R. D. M., 15 Jan 2019, In : International Journal of Cancer. 144, 2, p. 372-379 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genomic dissection of Bipolar Disorder and Schizophrenia, including 28 subphenotypes

Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., Mullins, N., Charney, A. W., Ori, A. P. S., Loohuis, L. M. O., Domenici, E., Di Florio, A., Papiol, S., Kalman, J. L., Trubetskoy, V., Adolfsson, R., Agartz, I., Agerbo, E., Akil, H., Albani, D. & 33 others, Albus, M., Alda, M., Alexander, M., Alliey-Rodriguez, N., Als, T. D., Amin, F., Anjorin, A., Arranz, M. J., Awasthi, S., Bacanu, S. A., Badner, J. A., Baekvad-Hansen, M., Bakker, S., Band, G., Barchas, J. D., Barroso, I., Bass, N., Bauer, M., Baune, B. T., Begemann, M., Bellenguez, C., Belliveau, R. A., Bellivier, F., Bender, S., Bene, J., Bergen, S. E., Berrettini, W. H., Kupka, R., Meijer, C. J., Posthuma, D., Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, 14 Jun 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticleAcademicpeer-review

Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to journalArticleAcademicpeer-review

Genomics of Alzheimer’s disease

van de Weijer, M. P., Jansen, I. E., Verboven, A. H. A., Andreassen, O. A. & Posthuma, D., 1 Jan 2019, Personalized Psychiatry. Elsevier, p. 275-283 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Genotype-phenotype correlation in ATAD3A deletions: Not just of scientific relevance

Peeters-Scholte, C. M. P. C. D., Adama Van Scheltema, P. N., Klumper, F. J. C. M., Everwijn, S. M. P., Koopmans, M., Hoffer, M. J. V., Koopmann, T. T., Ruivenkamp, C. A. L., Steggerda, S. J., Van Der Knaap, M. S. & Santen, G. W. E., 1 Nov 2017, In : Brain. 140, 11, p. e66

Research output: Contribution to journalLetterAcademicpeer-review

Gestational surrogacy: results of 10 years of experience in the Netherlands

Peters, H. E., Schats, R., Verhoeven, M. O., Mijatovic, V., de Groot, C. J. M., Sandberg, J. L., Peeters, I. P. & Lambalk, C. B., 1 Dec 2018, In : Reproductive BioMedicine Online. 37, 6, p. 725-731 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Global Burden of Small Vessel Disease-Related Brain Changes on MRI Predicts Cognitive and Functional Decline

Jokinen, H., Koikkalainen, J., Laakso, H. M., Melkas, S., Nieminen, T., Brander, A., Korvenoja, A., Rueckert, D., Barkhof, F., Scheltens, P., Schmidt, R., Fazekas, F., Madureira, S., Verdelho, A., Wallin, A., Wahlund, L-O., Waldemar, G., Chabriat, H., Hennerici, M., O'Brien, J. & 4 others, Inzitari, D., Lötjönen, J., Pantoni, L. & Erkinjuntti, T., Jan 2020, In : Stroke. 51, 1, p. 170-178 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia

Oosterom, N., Griffioen, P. H., den Hoed, M. A. H., Pieters, R., de Jonge, R., Tissing, W. J. E., van den Heuvel-Eibrink, M. M. & Heil, S. G., 2018, In : PLoS ONE. 13, 7, e0199574.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay

Rumping, L., Tessadori, F., Pouwels, P. J. W., Vringer, E., Wijnen, J. P., Bhogal, A. A., Savelberg, S. M. C., Duran, K. J., Bakkers, M. J. G., Ramos, R. B. J. J., Schellekens, P. A. W., Kroes, H. Y., Klomp, D. W. J., Black, G. C. M., Taylor, R. L., Bakkers, J. P. W., Prinsen, H. C. M. T., van der Knaap, M. S., Dansen, T. B., Rehmann, H. & 6 others, Zwartkruis, F. J. T., Houwen, R. H. J., van Haaften, G., Verhoeven-Duif, N. M., Jans, J. J. M. & van Hasselt, P. M., 2019, In : Human Molecular Genetics. 28, 1, p. 96-104

Research output: Contribution to journalArticleAcademicpeer-review

Glucocorticoids decrease hippocampal and prefrontal activation during declarative memory retrieval in young men

Oei, N. Y. L., Elzinga, B. M., Wolf, O. T., de Ruiter, M. B., Damoiseaux, J. S., Kuijer, J. P. A., Veltman, D. J., Scheltens, P. & Rombouts, S. A. R. B., 1 Jun 2007, In : Brain Imaging and Behavior. 1, 1-2, p. 31-41 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Glutamate carrier involvement in mitochondrial dysfunctioning in the brain white matter

Hillen, AEJ. & Heine, VM., 18 Jun 2020, In : Frontiers in Molecular Biosciences.

Research output: Contribution to journalArticleAcademicpeer-review

Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells

Dusoswa, S. A., Horrevorts, S. K., Ambrosini, M., Kalay, H., Paauw, N. J., Nieuwland, R., Pegtel, M. D., Würdinger, T., van Kooyk, Y. & Garcia-Vallejo, J. J., 1 Jan 2019, In : Journal of Extracellular Vesicles. 8, 1, 1648995.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

Berenguer, J., Lagerweij, T., Zhao, X. W., Dusoswa, S., van der Stoop, P., Westerman, B., de Gooijer, M. C., Zoetemelk, M., Zomer, A., Crommentuijn, M. H. W., Wedekind, L. E., López-López, À., Giovanazzi, A., Bruch-Oms, M., Meulen-Muileman, I. H. V. D., Reijmers, R. M., van Kuppevelt, T. H., García-Vallejo, J. J., van Kooyk, Y., Tannous, B. A. & 9 others, Wesseling, P., Koppers-Lalic, D., Vandertop, W. P., Noske, D. P., van Beusechem, V. W., van Rheenen, J., Pegtel, D. M., van Tellingen, O. & Wurdinger, T., 13 Mar 2018, In : Journal of Extracellular Vesicles. 7, 1, 1446660.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gonadotrophins versus clomifene citrate with or without intrauterine insemination in women with normogonadotropic anovulation and clomifene failure (M-OVIN): a randomised, two-by-two factorial trial

Weiss, N. S., Nahuis, M. J., Bordewijk, E., Oosterhuis, J. E., Smeenk, J. M. J., Hoek, A., Broekmans, F. J. M., Fleischer, K., de Bruin, J. P., Kaaijk, E. M., Laven, J. S. E., Hendriks, D. J., Gerards, M. H., van Rooij, I. A. J., Bourdrez, P., Gianotten, J., Koks, C., Lambalk, C. B., Hompes, P. G., van der Veen, F. & 2 others, Mol, B. W. J. & van Wely, M., 2018, In : The Lancet. 391, 10122, p. 758-765

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gonadotrophins Versus Clomifene Citrate with or Without Intrauterine Insemination in Women with Normogonadotropic Anovulation and Clomifene Failure (M-OVIN): A Randomized, Two-by-Two Factorial Trial

Weiss, N. S., Nahuis, M. J., Bordewijk, E., Oosterhuis, J. E., Smeenk, J. M. J., Hoek, A., Broekmans, F. J. M., Fleischer, K., de Bruin, J. P., Kaaijk, E. M., Laven, J. S. E., Hendriks, D. J., Gerards, M. H., van Rooij, I. A. J., Bourdrez, P., Gianotten, J., Koks, C., Lambalk, C. B., Hompes, P. G., van der Veen, F. & 2 others, Mol, B. W. J. & van Wely, M., 2018, In : Obstetrical and Gynecological Survey. 73, 5, p. 283-284

Research output: Contribution to journalComment/Letter to the editorAcademic

Gonadotrophins versus clomiphene citrate with or without IUI in women with normogonadotropic anovulation and clomiphene failure: a cost-effectiveness analysis

Bordewijk, E. M., Weiss, N. S., Nahuis, M. J., Bayram, N., van Hooff, M. H. A., Boks, D. E. S., Perquin, D. A. M., Janssen, C. A. H., van Golde, R. J. T., Lambalk, C. B., Goddijn, M., Hompes, P. G., van der Veen, F., Mol, B. W. J., van Wely, M. & M-ovin study group, 1 Feb 2019, In : Human Reproduction. 34, 2, p. 276-284

Research output: Contribution to journalArticleAcademicpeer-review

Grading immunohistochemical markers p16INK4a and HPV E4 identifies productive and transforming lesions caused by low- and high-risk HPV within high-grade anal squamous intraepithelial lesions

Leeman, A., Jenkins, D., Marra, E., van Zummeren, M., Pirog, E. C., van de Sandt, M. M., van Eeden, A., Schim van der Loeff, M. F., Doorbar, J., de Vries, H. J. C., van Kemenade, F. J., Meijer, C. J. L. M. & Quint, W. G. V., 14 Jul 2019, In : British Journal of Dermatology.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Granulovacuolar degeneration bodies: red alert for neurons with MAPT/tau pathology

Wiersma, V. I. & Scheper, W., Jan 2020, In : Autophagy. 16, 1, p. 173-175 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology

Wiersma, V. I., van Ziel, A. M., Vazquez-Sanchez, S., Nölle, A., Berenjeno-Correa, E., Bonaterra-Pastra, A., Clavaguera, F., Tolnay, M., Musters, R. J. P., van Weering, J. R. T., Verhage, M., Hoozemans, J. J. M. & Scheper, W., 1 Dec 2019, In : Acta Neuropathologica. 138, 6, p. 943-970 28 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gray matter network disruptions and regional amyloid beta in cognitively normal adults

ten Kate, M., Visser, P. J., Bakardjian, H., Barkhof, F., Sikkes, S. A. M., van der Flier, W. M., Scheltens, P., Hampel, H., Habert, M. O., Dubois, B., Tijms, B. M., Audrain, C., Auffret, A., Bakardjian, H., Baldacci, F., Batrancourt, B., Benakki, I., Benali, H., Bertin, H., Bertrand, A. & 31 others, Boukadida, L., Cacciamani, F., Causse, V., Cavedo, E., Cherif Touil, S., Chiesa, P. A., Colliot, O., Dalla Barba, G., Depaulis, M., Dos Santos, A., Dubois, B., Dubois, M., Epelbaum, S., Fontaine, B., Francisque, H., Gagliardi, G., Genin, A., Genthon, R., Glasman, P., Gombert, F., Habert, M. O., Hampel, H., Hewa, H., Houot, M., Jungalee, N., Kas, A., Kilani, M., La Corte, V., Le Roy, F., Lehericy, S. & INSIGHT-preAD study group, 15 Mar 2018, In : Frontiers in Aging Neuroscience. 10, FEB, 67.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gray matter networks and cognitive impairment in multiple sclerosis

Rimkus, C. M., Schoonheim, M. M., Steenwijk, M. D., Vrenken, H., Eijlers, A. J., Killestein, J., Wattjes, M. P., Leite, C. C., Barkhof, F. & Tijms, B. M., 1 Mar 2019, In : Multiple Sclerosis. 25, 3, p. 382-391

Research output: Contribution to journalArticleAcademicpeer-review

Gray matter T1-w/T2-w ratios are higher in Alzheimer's disease

Pelkmans, W., Dicks, E., Barkhof, F., Vrenken, H., Scheltens, P., van der Flier, W. M. & Tijms, B. M., 2019, In : Human Brain Mapping. 40, 13, p. 3900-3909

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gray zones around diffuse large B cell lymphoma. Conclusions based on the workshop of the XIV meeting of the European Association for Hematopathology and the Society of Hematopathology in Bordeaux, France

Quintanilla-Martinez, L., de Jong, D., de Mascarel, A., Hsi, E. D., Kluin, P., Natkunam, Y., Parrens, M., Pileri, S. & Ott, G., 22 Dec 2009, In : JOURNAL OF HEMATOPATHOLOGY. 2, 4, p. 211-36 26 p.

Research output: Contribution to journalArticleAcademicpeer-review

Guanidinoacetate Methyltransferase Activity in Lymphocytes, for a Fast Diagnosis

Berends, L. M., Struys, E. A., Roos, B., Holwerda, U., Jansen, E. E. W., Salomons, G. S. & Wamelink, M. M. C., 2017, In : JIMD Reports. 37, p. 13-17 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Harmonization of neuroimaging biomarkers for neurodegenerative diseases: A survey in the imaging community of perceived barriers and suggested actions

Jovicich, J., Barkhof, F., Babiloni, C., Herholz, K., Mulert, C., van Berckel, B. N. M., Frisoni, G. B. & SRA-NED JPND Working Group, 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 69-73 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss

Görtz, A. L., Peferoen, L. A. N., Gerritsen, W. H., van Noort, J. M., Bugiani, M. & Amor, S., 1 Jun 2018, In : Neuropathology and Applied Neurobiology. 44, 4, p. 363-376 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Heat Shock Proteins: Old and Novel Roles in Neurodegenerative Diseases in the Central Nervous System

van Noort, J. M., Bugiani, M. & Amor, S., 2017, In : CNS and Neurological Disorders. Drug Targets. 16, 3, p. 244-256 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism

Heine, V. M. & Rowitch, D. H., Feb 2009, In : Journal of Clinical Investigation. 119, 2, p. 267-77 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hemidesmosome formation is initiated by the β4 integrin subunit, requires complex formation of β4 and HD1/plectin, and involves a direct interaction between β4 and the bullous pemphigoid antigen 180

Schaapveld, R. Q. J., Borradori, L., Geerts, D., Van Leusden, M. R., Kuikman, I., Nievers, M. G., Niessen, C. M., Steenbergen, R. D. M., Snijders, P. J. F. & Sonnenberg, A., 13 Jul 1998, In : Journal of Cell Biology. 142, 1, p. 271-284 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hemorragische cerebrates bij een neonatale Bacillus cereus infectie.

Vermeulen, R. J., van Elburg, RM., van der Zwet, W. C., Tutu-van Furth, AM., van der Knaap, MS. & Fetter, WPF., 2001, In : Nederlands Tijdschrift voor Geneeskunde. p. 2198

Research output: Contribution to journalArticleAcademicpeer-review

Heritability of reproductive hormones in adult male twins

Kuijper, E. A. M., Lambalk, C. B., Boomsma, D. I., van der Sluis, S., Blankenstein, M. A., de Geus, E. J. C. & Posthuma, D., Aug 2007, In : Human Reproduction. 22, 8, p. 2153-2159 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

HHV8/KSHV-Positive Lymphoproliferative Disorders and the Spectrum of Plasmablastic and Plasma Cell Neoplasms: 2015 SH/EAHP Workshop Report-Part 3

Chadburn, A., Said, J., Gratzinger, D., Chan, J. K. C., de Jong, D., Jaffe, E. S., Natkunam, Y. & Goodlad, J. R., 1 Feb 2017, In : American Journal of Clinical Pathology. 147, 2, p. 171-187 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

High-dimensional detection of imaging response to treatment in multiple sclerosis

Kanber, B., Nachev, P., Barkhof, F., Calvi, A., Cardoso, J., Cortese, R., Prados, F., Sudre, C. H., Tur, C., Ourselin, S. & Ciccarelli, O., 1 Dec 2019, In : NPJ digital medicine. 2, 1, 49.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access