Amsterdam Neuroscience - Cellular and Molecular Mechanisms

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2019

Characterization of brainstem TDP-43 distribution in FTD cases with ALS features

Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436

Research output: Contribution to journalMeeting AbstractAcademic

COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART-BRAIN AXIS: THE ROLE OF CEREBRAL BLOOD FLOW

Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H-P. H. P., Kappelle, J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A., Prins, N. D., Biessels, G. J., Barkhof, F. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P755-P756

Research output: Contribution to journalMeeting AbstractAcademic

COMORBID AMYLOID-β PATHOLOGY AFFECTS NEUROPSYCHIATRIC, NEUROPSYCHOLOGICAL, AND IMAGING FEATURES IN VASCULAR COGNITIVE DISORDERS

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P888-P889

Research output: Contribution to journalMeeting AbstractAcademic

Live birth rate is higher in primary subfertile women undergoing ICSI with high normal compared to low normal range TSH levels

Delprat, C., Van Dam, E., Van de Ven, P., Aissa, K., Ter Haar, M., Feenstra, Y., De Roos, A., Beelen, G., Schats, R. & Lambalk, C., Jul 2019, In : Human Reproduction. 34, p. 402-403

Research output: Contribution to journalMeeting AbstractAcademic

Temporal ordering of multimodal biomarker abnormality in multiple sclerosis

Dekker, I., Schoonheim, M. M., Venkatraghavan, V., Eijlers, A. J. C., Brouwer, I., Wattjes, M. P., Wink, A. M., Geurts, J. J. G., Uitdehaag, B. M. J., Oxtoby, N. P., Vrenken, H., Killestein, J., Barkhof, F. & Wottschel, V., Sep 2019, In : Multiple Sclerosis Journal. 25, p. 461-462

Research output: Contribution to journalMeeting AbstractAcademic

Thalamus atrophy progresses faster in subjects with early MS who have more damage in the connected white matter and who show increasing disability over time

Weeda, M. M., Pruis, I. J., Brouwer, I., Bellenberg, B., Schneider, R., Lukas, C., Barkhof, F., Vrenken, H. & Pouwels, P. J. W., Sep 2019, In : Multiple Sclerosis Journal. 25, p. 689-690

Research output: Contribution to journalMeeting AbstractAcademic

Thyroid function in neonates conceived after hysterosalpingography with iodinated contrast media

Van Welie, N., Portela, M., Roest, I., van Rijswijk, J., Verhoeve, H., Hoek, A., Bourdrez, P., de Bruin, J. P., Nap, A., Goddijn, M., Hooker, A., van Heteren, C., Koks, C., Lambalk, C., Dreyer, K., Mol, B. W., Finken, M. & Mijatovic, V., Sep 2019, In : Hormone Research in Paediatrics. 91, p. 351-351

Research output: Contribution to journalMeeting AbstractAcademic

2018

A distributed platform for making large scale manual reference datasets for MS lesion segmentation

Damangir, S., de Sitter, A., Brouwer, I., Guttmann, C. R. G., Pareto, D., Rovira, A., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 864-864

Research output: Contribution to journalMeeting AbstractAcademic

Creating accurate reference segmentations of deep GM structures in MS patients by fast semi-automated outlining

de Sitter, A., Bartel, F., Palotai, M., Burggraaff, J., Liu, Y., Simoes, J., Ruggieri, S., Schregel, K., Pinzon, A. M., Ropele, S., Rocca, M. A., Gasperini, C., Gallo, A., Schoonheimm, M., Amann, M., Yiannakas, M., Wattjes, M. P., Sastre-Garriga, J., Kappos, L., Filippi, M. & 7 others, Enzinger, C., Ciccarelli, O., Frederiksen, J., Barkhof, F., Guttmann, C. R. G., de Munck, J. C. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 620-622

Research output: Contribution to journalMeeting AbstractAcademic

Diagnosing frontotemporal dementia: clinico-pathological correlations in the Dutch population

Scarioni, M., Gami-Patel, P., van Swieten, J. C., Rozemuller, A., Dols, A., Hoozemans, J. J., Pijnenburg, Y. A. & Dijkstra, A. A., Jun 2018, In : European Journal of Neurology. 25, p. 478-478

Research output: Contribution to journalMeeting AbstractAcademic

High reproducibility and robustness to lesions, but large software and scanner effects for mean upper cervical cord area (MUCCA) measurement in MS

Middelkoop, S., Weeda, M. M., Steenwijk, M. D., Daams, M., Amiri, H., Brouwer, I., Killestein, J., Uitdehaag, B. M. J., Dekker, I., Lukas, C., Bellenberg, B., Barkhof, F., Pouwels, P. J. W. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 853-854

Research output: Contribution to journalMeeting AbstractAcademic

Monozygotic twin similarities for AD biomarkers: the Twin60+study

den Braber, A., Boomsma, D. I., Konijnenberg, E., Ten Kate, M., Tomassen, J., Teunissen, C., Barkhof, F., Van Berckel, B., De Geus, E. J. C., Scheltens, P. & Visser, P. J., Nov 2018, In : Behavior Genetics. 48, 6, p. 465-465

Research output: Contribution to journalMeeting AbstractAcademic

Primary subfertility is significantly associated with higher levels of Thyroid Stimulating Hormone within the normal range preceding In Vitro Fertilization

Delprat, C., Van Dam, E., Van de Ven, P., Aissa, K., Ter Haar, M., Feenstra, Y., De Roos, A., Beelen, G., Schats, R. & Lambalk, C., Jul 2018, In : Human Reproduction. 33, p. 465-465

Research output: Contribution to journalMeeting AbstractAcademic

Probability Maps of Glioblastoma Indicate Variation in Surgical Decisions Between 10 Surgical Teams

Müller, DMJ., Robe, P., Van der Brink, W., Ardon, H., Idema, B., Kloet, F., Barkhof, F., Vandertop, WP., Bello, L., Widhalm, G., Mandonnet, E., Berger, M. & Versélewel de Witt Hamer, PC., 9 Jan 2018, In : Neurosurgery.

Research output: Contribution to journalMeeting AbstractAcademic

Quantification of spinal cord atrophy in MS: which software, which vertebral level, spinal cord or brain MRI? A multi-centric, longitudinal comparison of three different volumetric approaches.

Lukas, C., Prados, F., Valsasina, P., Parmar, K., Brouwer, I., Bellenberg, B., Rovira, A., Chard, D., Kappos, L., Rocca, M. A., Filippi, M., Ciccarelli, O., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 88-90

Research output: Contribution to journalMeeting AbstractAcademic

Reliability of cross-sectional and longitudinal brain volume measurements in MS patients using FreeSurfer: a multi-vendor MRI study at 3 Tesla

Amiri, H., Renckens, S., Brouwer, I., Bosschaert, S., van Tuijl, R., Hagens, M., Killestein, J., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 515-515

Research output: Contribution to journalMeeting AbstractAcademic

Specific patterns of thalamic functional connectivity changes related to disability and cognitive impairment in multiple sclerosis

Schoonheim, M. M., Pinter, D., Meijer, K. A., Eijlers, A. J. C., Pirpamer, L., Khalil, M., Pichler, A., Fuchs, S., Fazekas, F., Uitdehaag, B. M. J., Barkhof, F., Enzinger, C. & Geurts, J. J. G., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 613-614

Research output: Contribution to journalMeeting AbstractAcademic

UFM1 founder mutation in the Roma population causes severe variant of Hypomyelination with Atrophy of the Basal ganglia and Cerebellum (H-ABC)

Hamilton, E. M., Bertini, E., Kalaydjieva, L., Morar, B., Dojcakova, D., Diodato, D., Wolf, N., Waisfisz, Q., Abbink, E. & van der Knaap, M. S., Jun 2018, In : European Journal of Neurology. 25, p. 31-32

Research output: Contribution to journalMeeting AbstractAcademic

2017

Apolipoprotein E epsilon 4 affects cognition, but not brain structure and functioning in patients with longstanding type 1 diabetes

van Duinkerken, E., Klein, M., Mograbi, D. C., Barkhof, F., Moll, A. C., Diamant, M., Snoek, F. J., Snoek, F. J. & IJzerman, R. G., Sep 2017, In : Diabetologia. 60, p. S580-S580

Research output: Contribution to journalMeeting AbstractAcademic

Apolipoprotein E epsilon 4 Affects Cognition, but Not Brain Structure and Functioning in Patients with Long-Standing Type 1 Diabetes

Van Duinkerken, E., Klein, M., Mograbi, D. C., Barkhof, F., Moll, A. C., Diamant, M., Snoek, F. J. & Ij, R. G., 1 Jun 2017, In : Diabetes. 66, p. A470-A470

Research output: Contribution to journalMeeting AbstractAcademic

Depression in multiple sclerosis: structural and functional disconnection in the fronto-limbic system

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J. W., Smit, J. H., Uitdehaag, B. M. J., Geurts, J. J. G., van Oppen, P. & Hulst, H. E., Oct 2017, In : Multiple Sclerosis Journal. 23, p. 538-539

Research output: Contribution to journalMeeting AbstractAcademic

Donor macrophages and remyelination in metachromatic leukodystrophy

Wolf, N., Westerveld, A., van Rappard, D., Breur, M., Vanderver, A., van der Knaap, M. S., Boelens, J. J. & Bugiani, M., Jun 2017, In : GLIA. 65, p. E542-E542

Research output: Contribution to journalMeeting AbstractAcademic

Epilepsy and abnormal potassium dynamics upon loss of function of the astrocyte specific protein MLC1

Min, R., Dubey, M., Brouwers, E., Hamilton, E. M. C., Stiedl, O., Bugiani, M., Koch, H., Wykes, R. C., Mansvelder, H. D. & van der Knaap, M. S., Jun 2017, In : GLIA. 65, p. E290-E291

Research output: Contribution to journalMeeting AbstractAcademic

Fronto-limbic structural and functional changes and depression in multiple sclerosis: is there a relationship with cognition?

van Geest, Q., Boeschoten, R. E., Keijzer, M. J., Steenwijk, M. D., Pouwels, P. J. W., Smit, J. H., Uitdehaag, B. M. J., Van Oppen, P., Geurts, J. J. G. & Hulst, H. E., Jul 2017, In : Multiple Sclerosis Journal. 23, 8, p. NP3-NP3

Research output: Contribution to journalMeeting AbstractAcademic

ImmunoPET imaging to assess target engagement: Experience from Zr-89-anti-HER3 mAb (GSK2849330) in patients with solid tumors

Mcgeoch, A., van Oordt, C. M. D. H., Bergstrom, M., McSherry, I., Smith, D., Cleveland, M., Hoekstra, O., Vugts, D., Weber, A., Freedman, I., Huisman, M., Matheny, C., van Dongen, G. & Zhang, S., Oct 2017, In : European Journal of Nuclear Medicine and Molecular Imaging. 44, p. S314-S315

Research output: Contribution to journalMeeting AbstractAcademic

Impact of removing facial features from MR images of MS patients on automatic lesion and atrophy metrics

de Sitter, A., Visser, M., Brouwer, I., van Schijndel, R. A., Uitdehaag, B. M. J., Barkhof, F. & Vrenken, H., Oct 2017, In : Multiple Sclerosis Journal. 23, p. 226-226

Research output: Contribution to journalMeeting AbstractAcademic

Less cortical folding in adult patients with longstanding type 1 diabetes is related to cognition and diabetes duration

IJzerman, R. G., Steenwijk, M. D., Landeira-Fernandez, J., Klein, M., Barkhof, F., Moll, A. C., Diamant, M., Snoek, F. J. & van Duinkerken, E., Sep 2017, In : Diabetologia. 60, p. S552-S552

Research output: Contribution to journalMeeting AbstractAcademic

Less Cortical Folding in Adult Patients with Long-Standing Type 1 Diabetes Is Related to Cognition and Diabetes Duration

Van Duinkerken, E., Steenwijk, M. D., Landeira-Fernandez, J., Klein, M., Barkhof, F., Moll, A. C., Diamant, M., Snoek, F. J. & Ijzerman, R. G., 1 Jun 2017, In : Diabetes. 66, p. A223-A223

Research output: Contribution to journalMeeting AbstractAcademic

Neuropathological assessment of cognitively healthy centenarians - The 100-Plus Study

Ganz, A. B., de Reus, M. A., Smit, A. B., Scheltens, P., Rozemuller, A., Hoozemans, J. J. M. & Holstege, H., Feb 2017, In : Neuropathology and Applied Neurobiology. 43, p. 14-15

Research output: Contribution to journalMeeting AbstractAcademic

Profiling peripheral metabolic dysregulation in Alzheimer’s disease: The added value of multiple signatures. Alzheimer’s & Dementia

de Leeuw, F. A., Peeters, C. F. W., Kester, M. I., Harms, A. C., Hankemeier, T., Struys, E. A., Demirkan, A., Scheltens, P., van Vlijmen, H. W. T., van de Wiel, M. A., van Duijn, C. M., van der Flier, W. M. & Teunissen, C. E., Jun 2017, In : Alzheimers & Dementia. 13, 7, p. P1024-P1025

Research output: Contribution to journalMeeting AbstractAcademic

Structural MRI predictors of cognitive decline in MS

Eijlers, A. J., Dekker, I., Meijer, K. A., Uitdehaag, B. M., Barkhof, F., Geurts, J. J. & Schoonheim, M. M., Oct 2017, In : Multiple Sclerosis Journal. 23, p. 25-26

Research output: Contribution to journalMeeting AbstractAcademic

The multiple faces of TUBB4A mutations: from hypomyelination to adult dystonia

Hamilton, E. M., Bugiani, M., Wolf, N. I., Vanderver, A., Duncan, I., Abbink, T. E. & van der Knaap, M. S., Jul 2017, In : European Journal of Neurology. 24, p. 74-74

Research output: Contribution to journalMeeting AbstractAcademic

2016

Activation of the unfolded protein response is not a common feature in human prion disease

Hoozemans, J. J. M., Wiersma, V. I., van Hecke, W., Scheper, W. & Rozemuller, J. M., Mar 2016, In : Neuropathology and Applied Neurobiology. 42, p. 29-30

Research output: Contribution to journalMeeting AbstractOther research output

Insomnia: restless REM sleep promotes nocturnal mentation and hyperarousal by interfering with the resolution of emotional distress

Wassing, R., Benjamins, J. S., Dekker, K., Moens, S., Spiegelhalder, K., Feige, B., Riemann, D., van der Sluis, S., Van der Werf, Y. D., Talamini, L. M., Walker, M., Schalkwijk, F. & Van Someren, E. J. W., Sep 2016, In : Journal of Sleep Research. 25, p. 31-31

Research output: Contribution to journalMeeting AbstractOther research output

THE MEASUREMENT OF HIPPOCAMPAL ATROPHY RATES WITH MRI FOR A 3-YEAR STUDY APPEARS TO BE AT LEAST 3 TIMES MORE SENSITIVE THAN A 1-YEAR STUDY BASED ON BACK-TO-BACK REPRODUCIBILITY

Cover, K. S., van Schijndel, R. A., Versteeg, A., Leung, K. K., Redolfi, A., Manset, D., Damangir, S., Bosco, P., Vrenken, H., van Dijk, B. W., Frisoni, G. B. & Barkhof, F., 17 Oct 2016, In : Alzheimers & Dementia. 12, 7, p. P99-P100

Research output: Contribution to journalMeeting AbstractAcademic