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2020

A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., A. C. ’t Hoen, P., van Meurs, J., Brooks, A. I., Boomsma, D. I., Penninx, B. W. J. H. & BIOS Consortium, Feb 2020, In : European Journal of Human Genetics. 28, 2, p. 253-263 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Affect fluctuations examined with ecological momentary assessment in patients with current or remitted depression and anxiety disorders

Schoevers, R. A., van Borkulo, C. D., Lamers, F., Servaas, M. N., Bastiaansen, J. A., Beekman, A. T. F., van Hemert, A. M., Smit, J. H., Penninx, B. W. J. H. & Riese, H., 1 Apr 2020, In : Psychological Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

An Emotional Neglect-Personality Disorder Approach: Quantifying a Dimensional Transdiagnostic Model of Trauma-Related and Personality Disorders

Wildschut, M., Swart, S., Langeland, W., Smit, J. H. & Draijer, N., 1 Apr 2020, In : Journal of Personality Disorders. 34, 2, p. 250-261 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

Logue, M. W., Miller, M. W., Wolf, E. J., Huber, B. R., Morrison, F. G., Zhou, Z., Zheng, Y., Smith, A. K., Daskalakis, N. P., Ratanatharathorn, A., Uddin, M., Nievergelt, C. M., Ashley-Koch, A. E., Baker, D. G., Beckham, J. C., Garrett, M. E., Boks, M. P., Geuze, E., Grant, G. A., Hauser, M. A. & 19 others, Kessler, R. C., Kimbrel, N. A., Maihofer, A. X., Marx, C. E., Qin, X-J., Risbrough, V. B., Rutten, B. P. F., Stein, M. B., Ursano, R. J., Vermetten, E., Vinkers, C. H., Ware, E. B., Stone, A., Schichman, S. A., McGlinchey, R. E., Milberg, W. P., Hayes, J. P., Verfaellie, M. & Traumatic Stress Brain Study Group, 14 Mar 2020, In : Clinical epigenetics. 12, 1, p. 46 46.

Research output: Contribution to journalArticleAcademicpeer-review

A network meta-analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression

Cuijpers, P., Noma, H., Karyotaki, E., Vinkers, C. H., Cipriani, A. & Furukawa, T. A., 2020, In : World Psychiatry. 19, 1, p. 92-107 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Are Apathy and Depressive Symptoms Related to Vascular White Matter Hyperintensities in Severe Late Life Depression?

Oudega, M. L., Siddiqui, A., Wattjes, M. P., Barkhof, F., Kate, M. T., Muller, M., Bouckaert, F., Vandenbulcke, M., De Winter, F. L., Sienaert, P., Stek, M. L., Comijs, H. C., Korten, N. C. M., Emsell, L., Eikelenboom, P., Rhebergen, D., van Exel, E. & Dols, A., 1 Jan 2020, In : Journal of Geriatric Psychiatry and Neurology.

Research output: Contribution to journalArticleAcademicpeer-review

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 291 others, Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Hofmann, A., Jiménez, E., Kahn, J. P., Kassem, L., Kuo, P. H., Kato, T., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Tortorella, A., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., Colom, F., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O’Donovan, C., Ozaki, N., Ösby, U., Pfennig, A., Potash, J. B., Reif, A., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. V., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Ising, M., Jansen, R., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Maj, M., Turecki, G., Vieta, E., Veeh, J., Witt, S. H., Wright, A., Zandi, P. P., Mitchell, P. B., Bauer, M., Alda, M., Rietschel, M., McMahon, F. J., Schulze, T. G., Baune, B. T. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

'Big Five' personality characteristics are associated with loneliness but not with social network size in older adults, irrespective of depression

Schutter, N., Koorevaar, L., Holwerda, T. J., Stek, M. L., Dekker, J. & Comijs, H. C., Jan 2020, In : International Psychogeriatrics. 32, 1, p. 53-63 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biphasic Glucocorticoid Rhythm in One-Month-Old Infants: Reflection of a Developing HPA-Axis?

Hollanders, J. J., van der Voorn, B., de Goede, P., Toorop, A. A., Dijkstra, L. R., Honig, A., Rotteveel, J., Dolman, K. M., Kalsbeek, A. & Finken, M. J. J., 1 Mar 2020, In : The Journal of clinical endocrinology and metabolism. 105, 3, dgz089.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group

Han, L. K. M., Dinga, R., Hahn, T., Ching, C. R. K., Eyler, L. T., Aftanas, L., Aghajani, M., Aleman, A., Baune, B. T., Berger, K., Brak, I., Filho, G. B., Carballedo, A., Connolly, C. G., Couvy-Duchesne, B., Cullen, K. R., Dannlowski, U., Davey, C. G., Dima, D., Duran, F. L. S. & 126 others, Enneking, V., Filimonova, E., Frenzel, S., Frodl, T., Fu, C. H. Y., Godlewska, B. R., Gotlib, I. H., Grabe, H. J., Groenewold, N. A., Grotegerd, D., Gruber, O., Hall, G. B., Harrison, B. J., Hatton, S. N., Hermesdorf, M., Hickie, I. B., Ho, T. C., Hosten, N., Jansen, A., Kähler, C., Kircher, T., Klimes-Dougan, B., Krämer, B., Krug, A., Lagopoulos, J., Leenings, R., MacMaster, F. P., MacQueen, G., McIntosh, A., McLellan, Q., McMahon, K. L., Medland, S. E., Mueller, B. A., Mwangi, B., Osipov, E., Portella, M. J., Pozzi, E., Reneman, L., Repple, J., Rosa, P. G. P., Sacchet, M. D., Sämann, P. G., Schnell, K., Schrantee, A., Simulionyte, E., Soares, J. C., Sommer, J., Stein, D. J., Steinsträter, O., Strike, L. T., Thomopoulos, S. I., van Tol, M. J., Veer, I. M., Vermeiren, R. R. J. M., Walter, H., van der Wee, N. J. A., van der Werff, S. J. A., Whalley, H., Winter, N. R., Wittfeld, K., Wright, M. J., Wu, M. J., Völzke, H., Yang, T. T., Zannias, V., de Zubicaray, G. I., Zunta-Soares, G. B., Abé, C., Alda, M., Andreassen, O. A., Bøen, E., Bonnin, C. M., Canales-Rodriguez, E. J., Cannon, D., Caseras, X., Chaim-Avancini, T. M., Elvsåshagen, T., Favre, P., Foley, S. F., Fullerton, J. M., Goikolea, J. M., Haarman, B. C. M., Hajek, T., Henry, C., Houenou, J., Howells, F. M., Ingvar, M., Kuplicki, R., Lafer, B., Landén, M., Machado-Vieira, R., Malt, U. F., McDonald, C., Mitchell, P. B., Nabulsi, L., Otaduy, M. C. G., Overs, B. J., Polosan, M., Pomarol-Clotet, E., Radua, J., Rive, M. M., Roberts, G., Ruhe, H. G., Salvador, R., Sarró, S., Satterthwaite, T. D., Savitz, J., Schene, A. H., Schofield, P. R., Serpa, M. H., Sim, K., Soeiro-de-Souza, M. G., Sutherland, A. N., Temmingh, H. S., Timmons, G. M., Uhlmann, A., Vieta, E., Wolf, D. H., Zanetti, M. V., Jahanshad, N., Thompson, P. M., Veltman, D. J., Penninx, B. W. J. H., Marquand, A. F., Cole, J. H. & Schmaal, L., 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: Evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group

Opel, N., Thalamuthu, A., Milaneschi, Y., Grotegerd, D., Flint, C., Leenings, R., Goltermann, J., Richter, M., Hahn, T., Woditsch, G., Berger, K., Hermesdorf, M., McIntosh, A., Whalley, H. C., Harris, M. A., MacMaster, F. P., Walter, H., Veer, I. M., Frodl, T., Carballedo, A. & 44 others, Krug, A., Nenadic, I., Kircher, T., Aleman, A., Groenewold, N. A., Stein, D. J., Soares, J. C., Zunta-Soares, G. B., Mwangi, B., Wu, M. J., Walter, M., Li, M., Harrison, B. J., Davey, C. G., Cullen, K. R., Klimes-Dougan, B., Mueller, B. A., Sämann, P. G., Penninx, B., Nawijn, L., Veltman, D. J., Aftanas, L., Brak, I. V., Filimonova, E. A., Osipov, E. A., Reneman, L., Schrantee, A., Grabe, H. J., Van der Auwera, S., Wittfeld, K., Hosten, N., Völzke, H., Sim, K., Gotlib, I. H., Sacchet, M. D., Lagopoulos, J., Hatton, S. N., Hickie, I., Pozzi, E., Thompson, P. M., Jahanshad, N., Schmaal, L., Baune, B. T. & Dannlowski, U., 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Bumetanide for Core Symptoms of Autism Spectrum Disorder (BAMBI): a Single Center, Double-Blinded, Participant-Randomized, Placebo-Controlled, Phase 2, Superiority Trial

Sprengers, J., Van Andel, D. M., Zuithoff, N. P. A., Keijzer-Veen, M. G., Schulp, A. J. A., Scheepers, F. E., Lilien, M. R., Oranje, B. & Bruining, H., 2020, (Accepted/In press) In : Journal of the American Academy of Child and Adolescent Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Cannabinoids and psychotic symptoms: A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene

Boks, M. P., He, Y., Schubart, C. D., Gastel, W. V., Elkrief, L., Huguet, G., Eijk, K. V., Vinkers, C. H., Kahn, R. S., Paus, T., Conrod, P., Hol, E. M. & de Witte, L. D., 1 Jan 2020, (Accepted/In press) In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticleAcademicpeer-review

Cerebral organoids: a human model for AAV capsid selection and therapeutic transgene efficacy in the brain.

Depla, D. J., Sogorb-Gonzalez, M., Mulder, L., Heine, VM., Konstantinova, P., van Deventer, S. J., Wolthers, KC., Pajkrt, D., Sridhar, A. & Evers, M. M., 1 Jun 2020, In : Molecular Therapy - Methods and Clinical Development.

Research output: Contribution to journalArticleAcademicpeer-review

Childhood overweight and obesity and the risk of depression across the lifespan

Gibson-Smith, D., Halldorsson, T. I., Bot, M., Brouwer, I. A., Visser, M., Thorsdottir, I., Birgisdottir, B. E., Gudnason, V., Eiriksdottir, G., Launer, L. J., Harris, T. B. & Gunnarsdottir, I., 21 Jan 2020, In : BMC Pediatrics. 20, 1, p. 25 1 p., 25.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Clues For Genetic Anticipation In Multiple Endocrine Neoplasia Type 1

van den Broek, M. F. M., van Nesselrooij, B. P. M., Pieterman, C. R. C., Verrijn Stuart, A. A., van de Ven, A. C., de Herder, W. W., Dekkers, O. M., Drent, M. L., Havekes, B., Kerstens, M. N., Bisschop, P. H. & Valk, G. D., 1 Jul 2020, In : The Journal of clinical endocrinology and metabolism. 105, 7

Research output: Contribution to journalArticleAcademicpeer-review

COVID-19 and child and adolescent psychiatry: an unexpected blessing for part of our population?

Bruining, H., Bartels, M., Polderman, T. J. C. & Popma, A., 2020, (Accepted/In press) In : European Child and Adolescent Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Degree of genetic liability for Alzheimer's disease associated with specific proteomic profiles in cerebrospinal fluid

Alzheimer's Disease Neuroimaging Initiative, 24 Mar 2020, In : Neurobiology of Aging.

Research output: Contribution to journalArticleAcademicpeer-review

Depression profilers and immuno-metabolic dysregulation: Longitudinal results from the NESDA study

Lamers, F., Milaneschi, Y., Vinkers, C. H., Schoevers, R. A., Giltay, E. J. & Penninx, B. W. J. H., 6 Apr 2020, In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticleAcademicpeer-review

Diurnal rhythmicity in breast-milk glucocorticoids, and infant behavior and sleep at age 3 months

Toorop, A. A., van der Voorn, B., Hollanders, J. J., Dijkstra, L. R., Dolman, K. M., Heijboer, A. C., Rotteveel, J., Honig, A. & Finken, M. J. J., 1 Jan 2020, (Accepted/In press) In : Endocrine. 68, 3, 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis

the DEPRESsion Screening Data (DEPRESSD) Collaboration, 1 Jan 2020, In : Statistical Methods in Medical Research.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study

Deianova, N., Hassani, S. E. M. E., Niemarkt, H. J., Cossey, V., Kaam, A. H. V., Jenken, F., Weissenbruch, M. M. V., Doedes, E. M., Baelde, K., Menezes, R., Benninga, M. A., Jonge, W. J. D., Boer, N. K. D. & Meij, T. G. D., 11 May 2020, In : Biosensors. 10, 5

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

First in man study of [18F]fluoro-PEG-folate PET: a novel macrophage imaging technique to visualize rheumatoid arthritis

Verweij, N. J. F., Yaqub, M., Bruijnen, S. T. G., Pieplenbosch, S., ter Wee, M. M., Jansen, G., Chen, Q., Low, P. S., Windhorst, A. D., Lammertsma, A. A., Hoekstra, O. S., Voskuyl, A. E. & van der Laken, C. J., 23 Jan 2020, In : Scientific Reports. 10, 1, 1047.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Frontotemporal Dementia: Correlations Between Psychiatric Symptoms and Pathology

Scarioni, M., Gami-Patel, P., Timar, Y., Seelaar, H., van Swieten, J. C., Rozemuller, A. J. M., Dols, A., Scarpini, E., Galimberti, D., Hoozemans, J. J. M., Pijnenburg, Y. A. L., Dijkstra, A. A. & Netherlands Brain Bank, 1 Jan 2020, (Accepted/In press) In : Annals of Neurology. 87, 6, 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

de las Fuentes, L., Sung, Y. J., Noordam, R., Winkler, T., Feitosa, M. F., Schwander, K., Bentley, A. R., Brown, M. R., Guo, X., Manning, A., Chasman, D. I., Aschard, H., Bartz, T. M., Bielak, L. F., Campbell, A., Cheng, C. Y., Dorajoo, R., Hartwig, F. P., Horimoto, A. R. V. R., Li, C. & 203 others, Li-Gao, R., Liu, Y., Marten, J., Musani, S. K., Ntalla, I., Rankinen, T., Richard, M., Sim, X., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Vojinovic, D., Warren, H. R., Xuan, D., Alver, M., Boissel, M., Chai, J. F., Chen, X., Christensen, K., Divers, J., Evangelou, E., Gao, C., Girotto, G., Harris, S. E., He, M., Hsu, F. C., Kühnel, B., Laguzzi, F., Li, X., Lyytikäinen, L. P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Rueedi, R., Shu, X. O., Snieder, H., Sofer, T., Takeuchi, F., Verweij, N., Ware, E. B., Weiss, S., Yanek, L. R., Amin, N., Arking, D. E., Arnett, D. K., Bergmann, S., Boerwinkle, E., Brody, J. A., Broeckel, U., Brumat, M., Burke, G., Cabrera, C. P., Canouil, M., Chee, M. L., Chen, Y. D. I., Cocca, M., Connell, J., de Silva, H. J., de Vries, P. S., Eiriksdottir, G., Faul, J. D., Fisher, V., Forrester, T., Fox, E. F., Friedlander, Y., Gao, H., Gigante, B., Giulianini, F., Gu, C. C., Gu, D., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hunt, S., Ikram, M. A., Irvin, M. R., Kähönen, M., Kavousi, M., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Komulainen, P., Kraja, A. T., Krieger, J. E., Langefeld, C. D., Li, Y., Liang, J., Liewald, D. C. M., Liu, C. T., Liu, J., Lohman, K. K., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mook-Kanamori, D. O., Nalls, M. A., Nelson, C. P., Norris, J. M., O’Connell, J., Ogunniyi, A., Padmanabhan, S., Palmer, N. D., Pedersen, N. L., Perls, T., Peters, A., Petersmann, A., Peyser, P. A., Polasek, O., Porteous, D. J., Raffel, L. J., Rice, T. K., Rotter, J. I., Rudan, I., Rueda-Ochoa, O. L., Sabanayagam, C., Salako, B. L., Schreiner, P. J., Shikany, J. M., Sidney, S. S., Sims, M., Sitlani, C. M., Smith, J. A., Starr, J. M., Strauch, K., Swertz, M. A., Teumer, A., Tham, Y. C., Uitterlinden, A. G., Vaidya, D., van der Ende, M. Y., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Weir, D. R., Wen, W., Yao, J., Yu, B., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Bowden, D. W., Deary, I. J., Dörr, M., Esko, T., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kammerer, C. M., Kato, N., Lakka, T. A., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Marques-Vidal, P., Penninx, B. W. J. H., Samani, N. J., van der Harst, P., Wagenknecht, L. E., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Cooper, R. S., Correa, A., Evans, M. K., Gudnason, V., Hayward, C., Horta, B. L., Kelly, T. N., Kritchevsky, S. B., Levy, D., Palmas, W. R., Pereira, A. C., Province, M. M., Psaty, B. M., Ridker, P. M., Rotimi, C. N., Tai, E. S., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Rice, K., Gauderman, W. J., Morrison, A. C., North, K. E., Kardia, S. L. R., Caulfield, M. J., Elliott, P., Munroe, P. B., Franks, P. W., Rao, D. C., Fornage, M. & Lifelines Cohort Study, 1 Jan 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

Li, C., Stoma, S., Lotta, L. A., Warner, S., Albrecht, E., Allione, A., Arp, P. P., Broer, L., Buxton, J. L., Da Silva Couto Alves, A., Deelen, J., Fedko, I. O., Gordon, S. D., Jiang, T., Karlsson, R., Kerrison, N., Loe, T. K., Mangino, M., Milaneschi, Y., Miraglio, B. & 76 others, Pervjakova, N., Russo, A., Surakka, I., van der Spek, A., Verhoeven, J. E., Amin, N., Beekman, M., Blakemore, A. I., Canzian, F., Hamby, S. E., Hottenga, J. J., Jones, P. D., Jousilahti, P., Mägi, R., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Perola, M., Pietiläinen, K. H., Salomaa, V., Sillanpää, E., Suchiman, H. E., van Heemst, D., Willemsen, G., Agudo, A., Boeing, H., Boomsma, D. I., Chirlaque, M. D., Fagherazzi, G., Ferrari, P., Franks, P., Gieger, C., Eriksson, J. G., Gunter, M., Hägg, S., Hovatta, I., Imaz, L., Kaprio, J., Kaaks, R., Key, T., Krogh, V., Martin, N. G., Melander, O., Metspalu, A., Moreno, C., Onland-Moret, N. C., Nilsson, P., Ong, K. K., Overvad, K., Palli, D., Panico, S., Pedersen, N. L., Penninx, B. W. J. H., Quirós, J. R., Jarvelin, M. R., Rodríguez-Barranco, M., Scott, R. A., Severi, G., Slagboom, P. E., Spector, T. D., Tjonneland, A., Trichopoulou, A., Tumino, R., Uitterlinden, A. G., van der Schouw, Y. T., van Duijn, C. M., Weiderpass, E., Denchi, E. L., Matullo, G., Butterworth, A. S., Danesh, J., Samani, N. J., Wareham, N. J., Nelson, C. P., Langenberg, C. & Codd, V., 5 Mar 2020, In : American journal of human genetics. 106, 3, p. 389-404 16 p.

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Open Access

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 206 others, Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Howard, D. M., Ising, M., Jansen, R., Jones, I., Jones, L. A., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M., O’Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C., Breen, G. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23 Jan 2020, In : Molecular Psychiatry. 25, 7, 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Glutamate carrier involvement in mitochondrial dysfunctioning in the brain white matter

Hillen, AEJ. & Heine, VM., 18 Jun 2020, In : Frontiers in Molecular Biosciences.

Research output: Contribution to journalArticleAcademicpeer-review

Harmonised collection of data in youth mental health: Towards large datasets

Lavoie, S., Allott, K., Amminger, P., Bartholomeusz, C., Berger, M., Breakspear, M., Henders, A. K., Lee, R., Lin, A., McGorry, P., Rice, S., Schmaal, L. & Wood, S. J., 1 Jan 2020, In : The Australian and New Zealand Journal of Psychiatry. 54, 1, 11 p.

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Open Access

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 2020, In : Nature Communications. 11, 1, 39.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Heritability of Cortisol Production and Metabolism Throughout Adolescence

van Keulen, B. J., Dolan, C. V., Andrew, R., Walker, B. R., Hulshoff Pol, H. E., Boomsma, D. I., Rotteveel, J. & Finken, M. J. J., 1 Feb 2020, In : The Journal of clinical endocrinology and metabolism. 105, 2, dgz016.

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Open Access

Hormonal Treatment and Cardiovascular Risk Profile in Transgender Adolescents

Klaver, M., de Mutsert, R., van der Loos, M. A. T. C., Wiepjes, C. M., Twisk, J. W. R., den Heijer, M., Rotteveel, J. & Klink, D. T., Mar 2020, In : Pediatrics. 145, 3, e20190741.

Research output: Contribution to journalArticleAcademicpeer-review

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas

Liu, J., Lahousse, L., Nivard, M. G., Bot, M., Chen, L., van Klinken, J. B., Thesing, C. S., Beekman, M., van den Akker, E. B., Slieker, R. C., Waterham, E., van der Kallen, C. J. H., de Boer, I., Li-Gao, R., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L. J. M., Murad, S. D. & 29 others, Uitterlinden, A. G., Willemsen, G., Pool, R., Milaneschi, Y., van Heemst, D., Suchiman, H. E. D., Rutters, F., Elders, P. J. M., Beulens, J. W. J., van der Heijden, A. A. W. A., van Greevenbroek, M. M. J., Arts, I. C. W., Onderwater, G. L. J., van den Maagdenberg, A. M. J. M., Mook-Kanamori, D. O., Hankemeier, T., Terwindt, G. M., Stehouwer, C. D. A., Geleijnse, J. M., ‘t Hart, L. M., Slagboom, P. E., van Dijk, K. W., Zhernakova, A., Fu, J., Penninx, B. W. J. H., Boomsma, D. I., Demirkan, A., Stricker, B. H. C. & van Duijn, C. M., 1 Jan 2020, In : Nature Medicine. 26, 1, p. 110-117 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Long-Term Stability of Cortisol Production and Metabolism Throughout Adolescence: Longitudinal Twin Study

van Keulen, B. J., Dolan, C. V., Andrew, R., Walker, B. R., Hulshoff Pol, H. E., Boomsma, D. I., Rotteveel, J. & Finken, M. J. J., 25 Mar 2020, In : Twin Research and Human Genetics. 23, 1, p. 1-6 6 p.

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Open Access

Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report)

Fedko, I. O., Hottenga, J. J., Helmer, Q., Mbarek, H., Huider, F., Amin, N., Beulens, J. W., Bremmer, M. A., Elders, P. J., Galesloot, T. E., Kiemeney, L. A., Van Loo, H. M., Picavet, H. S. J., Rutters, F., Van Der Spek, A., Van De Wiel, A. M., Van Duijn, C., De Geus, E. J. C., Feskens, E. J. M., Hartman, C. A. & 6 others, Oldehinkel, A. J., Smit, J. H., Verschuren, W. M. M., Penninx, B. W. J. H., Boomsma, D. I. & Bot, M., 1 Jan 2020, (Accepted/In press) In : Psychological Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls

Bot, M., Milaneschi, Y., Al-Shehri, T., Amin, N., Garmaeva, S., Onderwater, G. L. J., Pool, R., Thesing, C. S., Vijfhuizen, L. S., Vogelzangs, N., Arts, I. C. W., Demirkan, A., van Duijn, C., van Greevenbroek, M., van der Kallen, C. J. H., Köhler, S., Ligthart, L., van den Maagdenberg, A. M. J. M., Mook-Kanamori, D. O., de Mutsert, R. & 12 others, Tiemeier, H., Schram, M. T., Stehouwer, C. D. A., Terwindt, G. M., Willems van Dijk, K., Fu, J., Zhernakova, A., Beekman, M., Slagboom, P. E., Boomsma, D. I., Penninx, B. W. J. H. & BBMRI-NL Metabolomics Consortium, 1 Mar 2020, In : Biological Psychiatry. 87, 5, p. 409-418 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nurse-Guided Internet-Delivered Cognitive Behavioral Therapy for Insomnia in General Practice: Results from a Pragmatic Randomized Clinical Trial

Van Der Zweerde, T., Lancee, J., Slottje, P., Bosmans, J. E., Van Someren, E. J. W. & Van Straten, A., 1 Jan 2020, (Accepted/In press) In : Psychotherapy and Psychosomatics. 89, 3, 11 p.

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Open Access

Optical coherence tomography angiography in preclinical Alzheimer's disease

van de Kreeke, J. A., Nguyen, H-T., Konijnenberg, E., Tomassen, J., den Braber, A., ten Kate, M., Yaqub, M., van Berckel, B., Lammertsma, A. A., Boomsma, D. I., Tan, S. H., Verbraak, F. & Visser, P. J., 2020, In : British Journal of Ophthalmology. 104, 2, p. 157-161

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Parametric methods for [18F]flortaucipir PET

Golla, S. S. V., Wolters, E. E., Timmers, T., Ossenkoppele, R., van der Weijden, C. W. J., Scheltens, P., Schwarte, L., Mintun, M. A., Devous Sr, M. D., Schuit, R. C., Windhorst, A. D., Lammertsma, A. A., Yaqub, M., van Berckel, B. N. M. & Boellaard, R., 1 Feb 2020, In : Journal of Cerebral Blood Flow and Metabolism. 40, 2, p. 365-373 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Physical activity as moderator of the association between APOE and cognitive decline in older adults: Results from three longitudinal cohort studies

Stringa, N., van Schoor, N. M., Milaneschi, Y., Ikram, M. A., Del Panta, V., Koolhaas, C. M., Voortman, T., Bandinelli, S., Wolters, F. J. & Huisman, M., 28 Feb 2020, In : The journals of gerontology. Series A, Biological sciences and medical sciences.

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Open Access

Physiological stress markers, mental health and objective physical function

Lever-van Milligen, B. A., Lamers, F., Smit, J. H. & Penninx, B. W. J. H., 14 Mar 2020, In : Journal of Psychosomatic Research. 133, p. 109996 109996.

Research output: Contribution to journalArticleAcademicpeer-review

Preclinical Detection of Non-catheter Related Late-onset Sepsis in Preterm Infants by Fecal Volatile Compounds Analysis: A Prospective, Multi-center Cohort Study

Berkhout, D. J. C., Niemarkt, H. J., Andriessen, P., Vijlbrief, D. C., Bomers, M. K., Cossey, V., Hulzebos, C. V., Van Kaam, A. H., Kramer, B. W., Van Lingen, R. A., Wicaksono, A. N., Covington, J. A., Van Weissenbruch, M. M., Benninga, M. A., De Boer, N. K. H. & De Meij, T. G. J., 1 Jan 2020, (Accepted/In press) In : Pediatric Infectious Disease Journal. p. 330-335 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Predicting individual clinical trajectories of depression with generative embedding

Frässle, S., Marquand, A. F., Schmaal, L., Dinga, R., Veltman, D. J., van der Wee, N. J. A., van Tol, M. J., Schöbi, D., Penninx, B. W. J. H. & Stephan, K. E., 2020, In : NeuroImage: Clinical. 26, 102213.

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Open Access

Propofol for endotracheal intubation in neonates: A dose-finding trial

de Kort, E. H. M., Prins, S. A., Reiss, I. K. M., Willemsen, S. P., Andriessen, P., van Weissenbruch, M. M. & Simons, S. H. P., 13 Jan 2020, In : Archives of Disease in Childhood-Fetal and Neonatal Edition.

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