Amsterdam Neuroscience - Neurodegeneration

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Meeting Abstract

The coarse-grained A beta plaque; a 'new' kid on the block in early-onset Alzheimer's disease, showing a strong association with both inflammatory and vascular changes

Boon, B. D. C., Bulk, M., Jonker, A. J., Morrema, T. H. J., van den Berg, E., Popovic, M., Walter, J., Kumar, S., Natte, R., van der Weerd, L., Bouwman, F. H., van de Berg, W. D. J., Hoozemans, J. J. M. & Rozemuller, A. J. M., Mar 2020, In : Neuropathology and Applied Neurobiology. 46, p. 39-40

Research output: Contribution to journalMeeting AbstractAcademic

2019

78. Machine Learning Classification of Obsessive-Compulsive Disorder Using Structural Neuroimaging Data: ENIGMA Working Group

Bruin, W., Shock, J., Thomas, R., Groenewold, N., Boedhoe, P., Thompson, P. M., van den Heuvel, O., Stein, D. J. & van Wingen, G., May 2019, In : Biological Psychiatry. 85, 10, p. S32

Research output: Contribution to journalMeeting AbstractAcademic

79. Association Between Illness Duration and Psychotropic Medication in Obsessive-Compulsive Disorder and Altered Brain Structural Covariance Networks: A Multi-Center Analysis

Yun, J-Y., Boedhoe, P. S. W., Jahanshad, N., Thompson, P. M., Stein, D. J., van den Heuvel, O. & Kwon, J. S., May 2019, In : Biological Psychiatry. 85, 10, p. S33

Research output: Contribution to journalMeeting AbstractAcademic

80. Subcortical Brain Volume, Regional Cortical Thickness and Surface Area Alterations Across ADHD, ASD, and OCD

Boedhoe, P., van Rooij, D., Hoogman, M., Schmaal, L., Thompson, P. M., Stein, D. J., Buitelaar, J., Franke, B. & van den Heuvel, O., May 2019, In : Biological Psychiatry. 85, 10, p. S33

Research output: Contribution to journalMeeting AbstractAcademic

Association between ventral subthalamic deep brain stimulation and apathy in Parkinson’s disease

Figee, M., Zoon, T., Boon, L., Potters, W., van Rootselaar, F. & de Bie, R., 22 Jan 2019, In : Brain stimulation. 12, 2, p. 522

Research output: Contribution to journalMeeting AbstractAcademic

Axonal degeneration as substrate of fractional anisotropy abnormalities in Multiple sclerosis cortex

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., Van de Berg, W. D., Schenk, G., Rocca, M. A., Filippi, M., Geurts, J. & Jonkman, L. E., Jul 2019, In : European Journal of Neurology. 26, p. 107-107

Research output: Contribution to journalMeeting AbstractAcademic

Characterization of brainstem TDP-43 distribution in FTD cases with ALS features

Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436

Research output: Contribution to journalMeeting AbstractAcademic

COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART-BRAIN AXIS: THE ROLE OF CEREBRAL BLOOD FLOW

Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H-P. H. P., Kappelle, J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A., Prins, N. D., Biessels, G. J., Barkhof, F. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P755-P756

Research output: Contribution to journalMeeting AbstractAcademic

Cognitive rehabilitation in patients with advanced progressive multiple sclerosis: possible within limits?

Prouskas, S. E., Chiaravalloti, N. D., Kant, N., Ball, K. K., de Groot, V., Uitdehaag, B. M. J., Geurts, J. J. G., Kooij, E. A. & Hulst, H. E., 10 Sep 2019, (Submitted) In : Multiple Sclerosis Journal. 228.

Research output: Contribution to journalMeeting AbstractAcademic

COMORBID AMYLOID-β PATHOLOGY AFFECTS NEUROPSYCHIATRIC, NEUROPSYCHOLOGICAL, AND IMAGING FEATURES IN VASCULAR COGNITIVE DISORDERS

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P888-P889

Research output: Contribution to journalMeeting AbstractAcademic

Delayed arrival of arterial blood in cortex is associated with decreased CSF levels of amyloid beta in predementia Alzheimer's disease

Palhaugen, L., Selnes, P., Tecelao, S., Lysvik, E. K., Ingala, S., Petr, J., Bjornerud, A., Mutsaerts, H. J. & Fladby, T., Jul 2019, In : European Journal of Neurology. 26, p. 358-358

Research output: Contribution to journalMeeting AbstractAcademic

Demyelination, Inflammation and Axonal Loss Explain Different Patterns of Fractional Anisotropy Abnormalities in MS Cortical Normal Appearing Gray Matter and Lesions

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., van de Berg, W., Schenk, G., Rocca, M., Filippi, M., Geurts, J. J. G. & Jonkman, L., 9 Apr 2019, In : Neurology. 92, 15

Research output: Contribution to journalMeeting AbstractAcademic

DEVELOPMENT AND USABILITY OF ADAPPT: AN ONLINE TOOL TO SUPPORT CLINICIANS, PATIENTS AND CAREGIVERS IN THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT AND ALZHEIMER’S DISEASE

Van Maurik, I. S., Visser, L. N. C., Pel-Littel, R., van Buchem, M., Zwan, M. D., Kunneman, M., Pelkmans, W., Bouwman, F. H., Minkman, M., Schoonenboom, N. S. M., Scheltens, P., Smets, E. M. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P163-P164

Research output: Contribution to journalMeeting AbstractAcademic

Harmonisation of PET/CT Performance for Brain Studies

Verwer, E. E., Golla, S. V. S., Kaalep, A., Lubberink, M., van Velden, F. H. P., Bettinardi, V., Yaqub, M. M., Sera, T., Rijnsdorp, S., Lammertsma, A. A. & Boellaard, R., Oct 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, SUPPL 1, p. S206-S207

Research output: Contribution to journalMeeting AbstractAcademic

Kinetics and 28 day test-retest repeatability and reproducibility of [C-11]UCB-J brain PET imaging

Tuncel, H., Boellaard, R., De Vries, E. F. J., Feltes, P. K., Verfaillie, S. C. J., Coomans, E. M., Wolters, E. E., Sweeney, S. P., Ryan, J. M., Ivarsson, M., Lynch, B. A., Schober, P., Scheltens, P., Schuit, R. C., Windhorst, A. D., De Deyn, P. P., van Berckel, B. N. M. & Golla, S. S. V., Oct 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, SUPPL 1, p. S32-S32

Research output: Contribution to journalMeeting AbstractAcademic

Local GM Demyelination and Remote Microstructural Damage in Connected WM Tracts both Contribute to Cortical Neurodegeneration in MS

Preziosa, P., Kiljan, S., Jonkman, L., van de Berg, W., Schenk, G., Rocca, M., Filippi, M., Geurts, J. J. G. & Steenwijk, M. D., 9 Apr 2019, In : Neurology. 92, 15

Research output: Contribution to journalMeeting AbstractAcademic

Simulating the effect of cerebral blood flow changes on quantification of [F-18]flutemetamol and [F-18]florbetaben studies

Heeman, F., Yaqub, M., Alves, I. L., Heurling, K., Gispert, J., Bullich, S., Foley, C., Boellaard, R. & Lammertsma, A. A., Jul 2019, In : Journal of Cerebral Blood Flow and Metabolism. p. 107-108

Research output: Contribution to journalMeeting AbstractAcademic

Temporal ordering of multimodal biomarker abnormality in multiple sclerosis

Dekker, I., Schoonheim, M. M., Venkatraghavan, V., Eijlers, A. J. C., Brouwer, I., Wattjes, M. P., Wink, A. M., Geurts, J. J. G., Uitdehaag, B. M. J., Oxtoby, N. P., Vrenken, H., Killestein, J., Barkhof, F. & Wottschel, V., Sep 2019, In : Multiple Sclerosis Journal. 25, p. 461-462

Research output: Contribution to journalMeeting AbstractAcademic

Thalamus atrophy progresses faster in subjects with early MS who have more damage in the connected white matter and who show increasing disability over time

Weeda, M. M., Pruis, I. J., Brouwer, I., Bellenberg, B., Schneider, R., Lukas, C., Barkhof, F., Vrenken, H. & Pouwels, P. J. W., Sep 2019, In : Multiple Sclerosis Journal. 25, p. 689-690

Research output: Contribution to journalMeeting AbstractAcademic

The in vivo and in vitro validation of two activin-receptor like kinase 5 targeting PET tracers

Rotteveel, L., Poot, A., Dijke, P., Bogaard, H. J., Lammertsma, A. & Windhorst, A., May 2019, In : Journal of Labelled Compounds and Radiopharmaceuticals. 62, p. S64-S65

Research output: Contribution to journalMeeting AbstractAcademic

2018

A distributed platform for making large scale manual reference datasets for MS lesion segmentation

Damangir, S., de Sitter, A., Brouwer, I., Guttmann, C. R. G., Pareto, D., Rovira, A., Barkhof, F. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 864-864

Research output: Contribution to journalMeeting AbstractAcademic

Comparing Amyloid PET Tracers and Interpretation Strategies: First Results from the CAPTAINs Study

Bischof, G., Bartenstein, P., Barthel, H., Van Berckel, B., Dore, V., Van Eimeren, T., Foster, N., Hammes, J., Lammertsma, A., Minoshima, S., Rowe, C., Sabri, O., Seibyl, J., Van Laere, K., Vandenberghe, R., Villemagne, V., Yakushev, I. & Drzezga, A., 1 May 2018, In : Journal of Nuclear Medicine. 59

Research output: Contribution to journalMeeting AbstractAcademic

Creating accurate reference segmentations of deep GM structures in MS patients by fast semi-automated outlining

de Sitter, A., Bartel, F., Palotai, M., Burggraaff, J., Liu, Y., Simoes, J., Ruggieri, S., Schregel, K., Pinzon, A. M., Ropele, S., Rocca, M. A., Gasperini, C., Gallo, A., Schoonheimm, M., Amann, M., Yiannakas, M., Wattjes, M. P., Sastre-Garriga, J., Kappos, L., Filippi, M. & 7 others, Enzinger, C., Ciccarelli, O., Frederiksen, J., Barkhof, F., Guttmann, C. R. G., de Munck, J. C. & Vrenken, H., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 620-622

Research output: Contribution to journalMeeting AbstractAcademic

Damage to long-range connections is especially relevant for cognitive impairment in multiple sclerosis.

Meijer, K. A., Schoonheim, M. M., Douw, L., Steenwijk, M. D. & Geurts, J. J., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 39-39

Research output: Contribution to journalMeeting AbstractAcademic

Demyelination, inflammation and axonal loss explain different patterns of fractional anisotropy abnormalities in MS cortical normal appering gray matter and lesions.

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A. G. M., van de Berg, W. D. J., Rocca, M. A., Filippi, M., Geurts, J. J. G. & Jonkman, L. E., Oct 2018, In : Multiple Sclerosis Journal. 24, p. 14-15

Research output: Contribution to journalMeeting AbstractAcademic

Diagnosing frontotemporal dementia: clinico-pathological correlations in the Dutch population

Scarioni, M., Gami-Patel, P., van Swieten, J. C., Rozemuller, A., Dols, A., Hoozemans, J. J., Pijnenburg, Y. A. & Dijkstra, A. A., Jun 2018, In : European Journal of Neurology. 25, p. 478-478

Research output: Contribution to journalMeeting AbstractAcademic

Distance to white matter tracts predicts STN deep brain stimulation outcome of tremor and dysarthria in Parkinson's disease

Boon, L., Prent, N., Potters, W., Caan, M., Berendse, H., de Bie, R., vd Munckhof, P., Schuurman, P. & van Rootselaar, A., Oct 2018, In : Movement Disorders. 33, p. S244-S245

Research output: Contribution to journalMeeting AbstractAcademic

Feasibility of brain PET/CT harmonization - a multicenter, multivendor pilot study

Boellaard, R., Golla, S., Kaleep, A., Lubberink, M., Van Velden, F., Bettinardi, V., Yaqub, M., Sera, T., Rijnsdorp, S. & Lammertsma, A., 1 May 2018, In : Journal of Nuclear Medicine. 59

Research output: Contribution to journalMeeting AbstractAcademic