Research Output 1983 2020

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2020

Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time

Struijs, S. Y., Lamers, F., Verdam, M. G. E., van Ballegooijen, W., Spinhoven, P., van der Does, W. & Penninx, B. W. J. H., 1 Jan 2020, In : Journal of Affective Disorders. 260, p. 77-83 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

7T MRI allows detection of disturbed cortical lamination of the medial temporal lobe in patients with Alzheimer's disease

Kenkhuis, B., Jonkman, L. E., Bulk, M., Buijs, M., Boon, B. D. C., Bouwman, F. H., Geurts, J. J. G., van de Berg, W. D. J. & van der Weerd, L., 1 Jan 2019, In : NeuroImage: Clinical. 21, 1 p., 101665.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

89 Zr-immuno-PET: towards a non-invasive clinical tool to measure target engagement of therapeutic antibodies in-vivo

Jauw, Y., o'Donoghue, J., Zijlstra, J., Hoekstra, O., Menke-van der Houven van Oordt, C. W., Morschhauser, F., Carrasquillo, J., Zweegman, S., Pandit-Taskar, N., Lammertsma, A., van Dongen, G., Boellaard, R., Weber, W. & Huisman, M., 30 May 2019, In : Journal of Nuclear Medicine. p. jnumed.118.224568

Research output: Contribution to journalArticleAcademicpeer-review

Aberrant resting-state oscillatory brain activity in Parkinson's disease patients with visual hallucinations: An MEG source-space study

Dauwan, M., Hoff, J. I., Vriens, E. M., Hillebrand, A., Stam, C. J. & Sommer, I. E., 1 Jan 2019, In : NeuroImage: Clinical. 22, 101752.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Lifelines Cohort Study & V. A. Million Veteran Program, 2019, In : Nature Genetics. 51, 6, p. 957-972

Research output: Contribution to journalArticleAcademicpeer-review

Accuracy of the Delirium Observational Screening Scale (DOS) as a screening tool for delirium in patients with advanced cancer

Neefjes, E. C. W., Van Der Vorst, M. J. D. L., Boddaert, M. S. A., Verdegaal, B. A. T. T., Beeker, A., Teunissen, S. C. C., Beekman, A. T. F., Zuurmond, W. W. A., Berkhof, J. & Verheul, H. M. W., 19 Feb 2019, In : BMC Cancer. 19, 1, 160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acid sphingomyelinase: No potential as a biomarker for multiple sclerosis

Leurs, C. E., Lopes Pinheiro, M. A., Wierts, L., den Hoedt, S., Mulder, M. T., Eijlers, A. J. C., Schoonheim, M. M., Balk, L. J., Uitdehaag, B. M. J., Killestein, J. & de Vries, H. E., 1 Feb 2019, In : Multiple Sclerosis and Related Disorders. 28, p. 44-49 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

A clinical interpretation of shame regulation in maladaptive perfectionism

Schalkwijk, F., Van Someren, E. J. W. & Wassing, R., 1 Feb 2019, In : Personality and Individual Differences. 138, p. 19-23 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

A comprehensive screening of copy number variability in dementia with Lewy bodies

Kun-Rodrigues, C., Orme, T., Carmona, S., Hernandez, D. G., Ross, O. A., Eicher, J. D., Shepherd, C., Parkkinen, L., Darwent, L., Heckman, M. G., Scholz, S. W., Troncoso, J. C., Pletnikova, O., Dawson, T., Rosenthal, L., Ansorge, O., Clarimon, J., Lleo, A., Morenas-Rodriguez, E., Clark, L. & 48 othersHonig, L. S., Marder, K., Lemstra, A., Rogaeva, E., St. George-Hyslop, P., Londos, E., Zetterberg, H., Barber, I., Braae, A., Brown, K., Morgan, K., Troakes, C., Al-Sarraj, S., Lashley, T., Holton, J., Compta, Y., van Deerlin, V., Serrano, G. E., Beach, T. G., Lesage, S., Galasko, D., Masliah, E., Santana, I., Pastor, P., Diez-Fairen, M., Aguilar, M., Tienari, P. J., Myllykangas, L., Oinas, M., Revesz, T., Lees, A., Boeve, B. F., Petersen, R. C., Ferman, T. J., Escott-Price, V., Graff-Radford, N., Cairns, N. J., Morris, J. C., Pickering-Brown, S., Mann, D., Halliday, G. M., Hardy, J., Trojanowski, J. Q., Dickson, D. W., Singleton, A., Stone, D. J., Guerreiro, R. & Bras, J., 1 Mar 2019, In : Neurobiology of Aging. 75, p. 223.e1-223.e10

Research output: Contribution to journalArticleAcademicpeer-review

Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families

Lakeman, I. M. M., Hilbers, F. S., Rodríguez-Girondo, M., Lee, A., Vreeswijk, M. P. G., Hollestelle, A., Seynaeve, C., Meijers-Heijboer, H., Oosterwijk, J. C., Hoogerbrugge, N., Olah, E., Vasen, H. F. A., van Asperen, C. J. & Devilee, P., 2019, In : Journal of Medical Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

A decrease in vitamin D levels is associated with methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia

Oosterom, N., Dirks, N. F., Heil, S. G., de Jonge, R., Tissing, W. J. E., Pieters, R., van den Heuvel-Eibrink, M. M., Heijboer, A. C. & Pluijm, S. M. F., 1 Jan 2019, In : Supportive Care in Cancer. 27, 1, p. 183-190 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A global overview of pleiotropy and genetic architecture in complex traits

Watanabe, K., Stringer, S., Frei, O., Umićević Mirkov, M., de Leeuw, C., Polderman, T. J. C., van der Sluis, S., Andreassen, O. A., Neale, B. M. & Posthuma, D., 2019, In : Nature Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

Aiding the diagnosis of dissociative identity disorder: pattern recognition study of brain biomarkers

Reinders, A. A. T. S., Marquand, A. F., Schlumpf, Y. R., Chalavi, S., Vissia, E. M., Nijenhuis, E. R. S., Dazzan, P., Jäncke, L. & Veltman, D. J., Sep 2019, In : The British journal of psychiatry : the journal of mental science. 215, 3, p. 536-544 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

A linear mixed-model approach to study multivariate gene–environment interactions

BIOS Consortium, 2019, In : Nature Genetics. 51, 1, p. 180-186 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Alzheimer disease biomarkers may aid in the prognosis of MCI cases initially reverted to normal

Alzheimer's Disease Neuroimaging Initiative, 2019, In : Neurology. 92, 23, p. e2699-e2705

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A meta-analysis of genome-wide association studies identifies multiple longevity genes

Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N. & 64 othersBecker, E. J., Beekman, M., Blanché, H. L., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J-F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L-P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J-M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., 2019, In : Nature Communications. 10, 1, 3669.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A multimodal MRI-based classification signature emerges just prior to symptom onset in frontotemporal dementia mutation carriers

Feis, R. A., Bouts, M. J. R. J., de Vos, F., Schouten, T. M., Panman, J. L., Jiskoot, L. C., Dopper, E. G. P., van der Grond, J., van Swieten, J. C. & Rombouts, S. A. R. B., 2019, In : Journal of Neurology, Neurosurgery and Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

A multi-shell multi-tissue diffusion study of brain connectivity in early multiple sclerosis

Tur, C., Grussu, F., Prados, F., Charalambous, T., Collorone, S., Kanber, B., Cawley, N., Altmann, D. R., Ourselin, S. B., Barkhof, F., Clayden, J. D., Toosy, A. T., Wheeler-Kingshott, C. A. M. G. & Ciccarelli, O., 2019, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Amygdala functioning during threat acquisition and extinction differentiates antisocial subtypes

Fanti, K. A., Konikou, K., Cohn, M., Popma, A. & Brazil, I. A., 2019, In : Journal of Neuropsychology.

Research output: Contribution to journalArticleAcademicpeer-review

Amyloid imaging of dutch-type hereditary cerebral amyloid angiopathy carriers

Dominantly Inherited Alzheimer Network, 2019, In : Annals of Neurology.

Research output: Contribution to journalArticleAcademicpeer-review

AMYPAD Diagnostic and Patient Management Study: Rationale and design

Frisoni, G. B., Barkhof, F., Altomare, D., Berkhof, J., Boccardi, M., Canzoneri, E., Collij, L., Drzezga, A., Farrar, G., Garibotto, V., Gismondi, R., Gispert, J-D., Jessen, F., Kivipelto, M., Lopes Alves, I., Molinuevo, J-L., Nordberg, A., Payoux, P., Ritchie, C., Savicheva, I. & 8 othersScheltens, P., Schmidt, M. E., Schott, J., Stephens, A., van Berckel, B., Vellas, B., Walker, Z. & Raffa, N., Mar 2019, In : Alzheimers & Dementia. 15, 3, p. 388-399

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

An automated home-cage-based 5-choice serial reaction time task for rapid assessment of attention and impulsivity in rats

Bruinsma, B., Terra, H., de Kloet, S. F., Luchicchi, A., Timmerman, A. J., Remmelink, E., Loos, M., Pattij, T. & Mansvelder, H. D., 2019, In : Psychopharmacology.

Research output: Contribution to journalArticleAcademicpeer-review

A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

IMBI Project, 2019, In : Alzheimer's and Dementia.

Research output: Contribution to journalArticleAcademicpeer-review

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, 2019, In : Acta Neuropathologica. 138, 2, p. 237-250

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A novel approach to improve stress regulation among traumatized youth in residential care: Feasibility study testing three game-based meditation interventions

Schuurmans, A. A. T., Nijhof, K. S., Scholte, R., Popma, A. & Otten, R., 2019, In : Early Intervention in Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Anterior Insular Cortex is Critical for the Propensity to Relapse Following Punishment-Imposed Abstinence of Alcohol Seeking

Campbell, E. J., Flanagan, J. P. M., Walker, L. C., Hill, M. K. R. I., Marchant, N. J. & Lawrence, A. J., 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 6, p. 1077-1087

Research output: Contribution to journalArticleAcademicpeer-review

A pilot study of the effects of running training on visuospatial memory in MS: A stronger functional embedding of the hippocampus in the default-mode network?

Huiskamp, M., Moumdjian, L., van Asch, P., Popescu, V., Schoonheim, M. M., Steenwijk, M. D., Vanzeir, E., van Wijmeersch, B., Geurts, J. J. G., Feys, P. & Hulst, H. E., 1 Jan 2019, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms

Charidimou, A., Zonneveld, H. I., Shams, S., Kantarci, K., Shoamanesh, A., Hilal, S., Yates, P. A., Boulouis, G., Na, H. K., Pasi, M., Biffi, A., Chai, Y. L., Chong, J. R., Wahlund, L-O., Clifford, J. R., Chen, C., Gurol, M. E., Goldstein, J. N., Na, D. L., Barkhof, F. & 4 othersSeo, S. W., Rosand, J., Greenberg, S. M. & Viswanathan, A., 2019, In : Neurology. 93, 4, p. e358-e371

Research output: Contribution to journalArticleAcademicpeer-review

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 2019, In : Behavior Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis

Eshaghi, A., Kievit, R. A., Prados, F., Sudre, C. H., Nicholas, J., Cardoso, M. J., Chan, D., Nicholas, R., Ourselin, S., Greenwood, J., Thompson, A. J., Alexander, D. C., Barkhof, F., Chataway, J. & Ciccarelli, O., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 22, p. 11020-11027

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

Nutma, E., Stephenson, J. A., Gorter, R. P., de Bruin, J., Boucherie, D. M., Donat, C. K., Breur, M., van der Valk, P., Matthews, P. M., Owen, D. R. & Amor, S., 3 Oct 2019, In : Brain : a journal of neurology.

Research output: Contribution to journalArticleAcademicpeer-review

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

Amor, S., 2019, (Accepted/In press) In : Brain.

Research output: Contribution to journalArticleAcademicpeer-review

Aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in immune-mediated optic neuritis at long-term follow-up

Petzold, A., Woodhall, M., Khaleeli, Z., Tobin, W. O., Pittock, S. J., Weinshenker, B. G., Vincent, A., Waters, P. & Plant, G. T., 2019, In : Journal of Neurology, Neurosurgery and Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

Milaneschi, Y., Peyrot, W. J., Nivard, M. G., Mbarek, H., Boomsma, D. I. & W.J.H. Penninx, B., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 219.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons

Meijer, M., Rehbach, K., Brunner, J. W., Classen, J. A., Lammertse, H. C. A., van Linge, L. A., Schut, D., Krutenko, T., Hebisch, M., Cornelisse, L. N., Sullivan, P. F., Peitz, M., Toonen, R. F., Brüstle, O. & Verhage, M., 2019, In : Cell Reports. 27, 7, p. 2199-2211.e6

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A spectral filter array camera for clinical monitoring and diagnosis: Proof of concept for skin oxygenation imaging

Bauer, J. R., Bruins, A. A., Hardeberg, J. Y. & Verdaasdonk, R. M., 2019, In : Journal of Imaging. 5, 8, 66.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access