Research Output

1989

Preclinical chemotherapy on human head and neck cancer xenografts grown in athymic nude mice

Braakhuis, B. J. M., Van Dongen, G. A. M. S., Bagnay, M., Van Walsum, M. & Snow, G. B., 1 Jan 1989, In : Head & Neck. 11, 6, p. 511-515 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Protective activity of nifedipine and R 58735 upon damage caused by global ischemia in the guinea pig heart-lung preparation

Boddeke, H. W. G. M., Jap, T. J. W., Hugtenburg, J. G., Heynis, J. B., Veldsema-Currie, R. D., Wilffert, B. & van Zwieten, P. A., 1 Sep 1989, In : Basic Research in Cardiology. 84, 5, p. 489-498 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Restricted usefulness of tetraethylammonium and 4-aminopyridine for the characterization of receptor-operated K+-channels

Drukarch, B., Kits, K. S., Leysen, J. E., Schepens, E. & Stoof, J. C., Sep 1989, In : British Journal of Pharmacology. 98, 1, p. 113-8 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Somatic cell gene therapy: the model of adenosine deaminase deficiency

Van Beusechem, V. W., Kukler, A., Bakx, T. A. & Valerio, D., Dec 1989, In : Bone Marrow Transplantation. 4 Suppl 4, p. 133-6 4 p.

Research output: Contribution to journalReview articleAcademic

Stimulation of D-2 dopamine receptors decreases the evoked in vitro release of [3H]acetylcholine from rat neostriatum: role of K+ and Ca2+

Drukarch, B., Schepens, E., Schoffelmeer, A. N. & Stoof, J. C., Jun 1989, In : Journal of Neurochemistry. 52, 6, p. 1680-5 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The differential effect of calcium antagonists on the positive inotropic effects induced by calcium and monensin in cardiac preparations of rats and guinea-pigs

Hugtenburg, J. G., Mathy, M. J., Beckeringh, J. J. & van Zwieten, P. A., 1 Jan 1989, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 340, 5, p. 558-566 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The drinker or the drink? The concept of alcoholism in the 19th and 20th century

Widdershoven, G. A. M. & Ter Meulen, R. H. J., 1 Jan 1989, In : Tijdschrift voor Alcohol, Drugs en Andere Psychotrope Stoffen. 15, 3, p. 105-112 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The puzzling role of vitamin A in cancer prevention (review)

De Vet, H. C. W., 1 Jan 1989, In : Anticancer Research. 9, 1, p. 145-152 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Transplantability of Human Head and Neck Squamous Cell Carcinomas in Athymic Nude Mice

Braakhuis, B. J. M., Laarman, D. A. W., Nauta, J. J. P., Van Walsum, M., Van Dongen, G. A. M. S. & Snow, G. B., 1 Jan 1989, In : Archives of Otolaryngology--Head and Neck Surgery. 115, 9, p. 1076-1078 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vertebral bone density in children: effect of puberty.

van Kuijk, C., Mar 1989, In : Radiology. 170, 3 Pt 1, p. 895-896 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

What is a safe heat dose which can be applied to normal brain tissue?

Sminia, P., Haveman, J. & Ongerboer de Visser, B. W., 1 Jan 1989, In : International journal of hyperthermia. 5, 1, p. 115-7 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1988

Activity of differentiation-inducing agents and conventional drugs in head and neck cancer xenografts

Dongen, G. V., Braakhuis, B. J. M., Bagnay, M., Leyva, A. & Snow, G. B., 1 Jan 1988, In : Acta Oto-Laryngologica. 105, 5-6, p. 488-493 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Anti-ischaemic activity of various calmodulin antagonists

Boddeke, H. W. G. M., Wilffert, B., Hugtenburg, J. G., Jap, T. J. W., Veldsema-Currie, R. D. & Van Zwieten, P. A., 1 Jan 1988, In : Pharmacology. 37, 4, p. 240-247 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of an antibody-capture IgM-enzyme-linked immunosorbent assay for diagnosis of acute Epstein-Barr virus infections

Wielaard, F., Scherders, J., Dagelinckx, C., Middeldorp, J. M., Sabbe, L. J. & Van Belzen, C., Sep 1988, In : Journal of Virological Methods. 21, 1-4, p. 105-15 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Doxorubicin treatment increases metastasis of prostate tumor (R3327-MatLyLu)

Geldof, A. A. & Rao, B. R., 1 Dec 1988, In : Anticancer Research. 8, 6, p. 1335-1339 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of local hyperthermia on the motor function of the rat sciatic nerve

Wondergem, J., Haveman, J., Rusman, V., Sminia, P. & Van Dijk, J. D., Mar 1988, In : International journal of radiation biology and related studies in physics, chemistry, and medicine. 53, 3, p. 429-38 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy and advantages in the use of low doses of anandron and estrogen combination in the treatment of prostate cancer

Rao, B. R., Geldof, A. A., van Der Wilt, C. L. & de Voogt, H. J., 1 Jan 1988, In : The Prostate. 13, 1, p. 69-78 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epitope-mapping on the Epstein-Barr virus major capsid protein using systematic synthesis of overlapping oligopeptides

Middeldorp, J. M. & Meloen, R. H., Sep 1988, In : Journal of Virological Methods. 21, 1-4, p. 147-59 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epstein-Barr virus specific marker molecules for early diagnosis of infectious mononucleosis

Middeldorp, J. M. & Herbrink, P., Sep 1988, In : Journal of Virological Methods. 21, 1-4, p. 133-46 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evidence for a role of heat-shock proteins in proliferation after heat treatment of synchronized mouse neuroblastoma cells

Van Dongen, G. & Van Wijk, R., 1 Jan 1988, In : Radiation Research. 113, 2, p. 252-267 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Further analysis of the neuropharmacological profile of 9-amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease

Drukarch, B., Leysen, J. E. & Stoof, J. C., 1988, In : Life Sciences. 42, 9, p. 1011-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interdigitating cells and dendritic cells of the mouse identified by monoclonal antibodies: interaction with lymphocyte subsets

Breel, M., Mebius, R. & Kraal, G., 1988, In : Advances in Experimental Medicine and Biology. 237, p. 757-63 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Merits and considerations in the use of anti-androgen

Rao, B. R., de Voogt, H. J., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1988, In : Journal of Steroid Biochemistry. 31, 4, p. 731-737 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Preclinical antitumor activity of 5-aza-2′-deoxycytidine agains human head and neck cancer xenografts

Braakhuis, B. J. M., van Dongen, G. A. M. S., van Walsum, M., Leyva, A. & Snow, G. B., 1 Dec 1988, In : Investigational New Drugs. 6, 4, p. 299-304 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prescription sequence analysis: A new and fast method for assessing certain adverse reactions of prescription drugs in large populations

Petri, H., De Vet, H. C. W., Naus, J. & Urquhart, J., 1 Jan 1988, In : Statistics in Medicine. 7, 11, p. 1171-1175 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Rapid diagnosis of genital herpes simplex infection by an indirect ELISA method

Skar, A. G., Middeldorp, J., Gundersen, T., Rollag, H. & Degrè, M., Dec 1988, In : NIPH annals. 11, 2, p. 59-65 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tetrahydro-aminoacridine: een veelbelovende 'therapie' voor de ziekte van Alzheimer?

Translated title of the contribution: Tetrahydroaminoacridine: a promising 'therapy' for Alzheimer's disease?Drukarch, B. & Stoof, J. C., 1 Oct 1988, In : Nederlands Tijdschrift voor Geneeskunde. 132, 40, p. 1833-5 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

The anti-ischaemic activity of the novel compound, CERM 11956, compared with that of bepridil and nifedipine in isolated guinea-pig hearts

Boddeke, E. W. G. M., Wilffert, B., Heynis, J. B., Hugtenburg, J. G., Jap, W. T. J., Veldsema-Currie, R. D. & Van Zwieten, P. A., 10 May 1988, In : European Journal of Pharmacology. 149, 3, p. 195-203 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The interaction of interdigitating cells and lymphocytes in vitro and in vivo

Breel, M., Mebius, R. & Kraal, G., Feb 1988, In : Immunology. 63, 2, p. 331-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1987

9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current

Drukarch, B., Kits, K. S., Van der Meer, E. G., Lodder, J. C. & Stoof, J. C., 2 Sep 1987, In : European Journal of Pharmacology. 141, 1, p. 153-7 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Androgen action blockade does not result in reduction in size but changes histology of the normal human prostate

De Voogt, H. J., Rao, B. R., Geldof, A. A., Gooren, L. J. G. & Bouman, F. G., 1 Jan 1987, In : The Prostate. 11, 4, p. 305-311 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A sensitive enzyme-linked immunosorbent assay for the detection of herpes simplex virus antigens

Middeldorp, J. M., Hooymans, A. M., Kocken, A. J., van Loon, A. M., Emsbroek, J. A. & Coutinho, R. A., Aug 1987, In : Journal of Virological Methods. 17, 1-2, p. 159-74 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dendritic cells of the mouse recognized by two monoclonal antibodies

Breel, M., Mebius, R. E. & Kraal, G., Nov 1987, In : European Journal of Immunology. 17, 11, p. 1555-9 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of an in vivo clonogenic cell assay for rat prostate metastatic tumor-R3327-MatLyLu

Geldof, A. A., Rao, B. R. & de Voogt, H. J., 1 Jun 1987, In : Urological Research. 15, 3, p. 139-144 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of 434 MHz microwave hyperthermia applied to the rat in the region of the cervical spinal cord

Sminia, P., Haveman, J., Wondergem, J., van Dijk, J. D. & Lebesque, J. V., 1 Sep 1987, In : International journal of hyperthermia. 3, 5, p. 441-52 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Renewal timing of long‐acting depot luteinizing hormone‐releasing hormone agonist (Zoladex) is critical in the treatment of hormone‐dependent rat prostatic carcinoma (R3327‐H)

Geldof, A. A., De Voogt, H. J. & Rao, B. R., 1 Jan 1987, In : The Prostate. 11, 3, p. 281-290 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Stress-induced Thermotolerance of the Cytoskeleton of Mouse Neuroblastoma N2A Cells and Rat Reuber H35 Hepatoma Cells

Wiegant, F. A. C., Van Bergen En Henegouwen, P. M. P., Van Dongen, G. & Linnemans, W. A. M., 15 Mar 1987, In : Cancer Research. 47, 6, p. 1674-1680 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1986

A rare complication of a benign ovarian teratoma

Vandertop, W. P., Eversdijk Smulders, T. A. & Petit, J. J., Feb 1986, In : The Netherlands journal of surgery. 38, 1, p. 24-5 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in‐vivo α1‐, α2‐ and 5‐HT2‐receptor antagonism and in‐vitro affinity for α1‐, α2‐ and 5‐HT2‐receptors: comparison with ketanserin

Korstanje, C., Sprenkels, R., Doods, H. N., Hugtenburg, J. G., Boddeke, E., Batink, H. D., Thoolen, M. J. M. C. & Van Zwieten, P. A., 1 Jan 1986, In : Journal of Pharmacy and Pharmacology. 38, 5, p. 374-379 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Direct effects of chemotherapeutic agents on rat prostate tumor clonogenic cells

Geldof, A. A., Rao, B. R. & De Voogt, H. J., 1 Jan 1986, In : Anticancer Research. 6, 4, p. 837-840 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effect of serum on heat response of synchronized mouse neuroblastoma cells: Protection of cell cycle progression, protein synthesis and survival

Van Dongen, G. & Van Wijk, R., 1 Jan 1986, In : International Journal of Radiation Biology. 50, 1, p. 77-91 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Glycolytic activity in human red cell populations separated by a combination of density and counterflow centrifugation. Evidence for an improved separation of red cells according to age

Jansen, G., Hepkema, B. G., van der Vegt, S. G. & Staal, G. E., Sep 1986, In : Scandinavian journal of haematology. 37, 3, p. 189-95 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immunofluorescence for detection of antibodies against human cytomegalovirus-induced membrane antigens

Middeldorp, J. M., Jongsma, J. & The, T. H., Sep 1986, In : Journal of Clinical Microbiology. 24, 3, p. 405-13 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increase of thermoresistance after growth stimulation of resting Reuber H35 hepatoma cells. Alteration of nuclear characteristics, non-histone chromosomal protein phosphorylation and basal heat shock protein synthesis

Van Dongen, G., Geilenkirchen, W. L. M., Van Rijn, J. & Van Wijk, R., 1 Jan 1986, In : Experimental Cell Research. 166, 2, p. 427-441 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Killing of human cytomegalovirus-infected fibroblasts by antiviral antibody and complement

Middeldorp, J. M., Jongsma, J. & The, T. H., Jan 1986, In : Journal of Infectious Diseases. 153, 1, p. 48-55 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Letters to the editor

De Vet, H. C. W. & Van Leeuwen, F. E., 1 Jan 1986, In : American Journal of Epidemiology. 123, 3, 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

On the reliability of historical dietary information

De Vet, H. C. W. & Van Leeuwen, F. E., 1 Jan 1986, In : American Journal of Epidemiology. 123, 3, 1 p.

Research output: Contribution to journalLetterAcademicpeer-review

Use of CI-920 in the characterization of the methotrexate transport defects in a resistant human leukemic CCRF-CEM cell line

Jansen, G., Schornagel, J. H., Rijksen, G. & de Gier, J., 1986, In: "Chemistry and Biology of Pteridines". Cooper, B. A. & Whitehead, V. M. (eds.). Walter de Gruyter, p. 543-546 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionProfessional

1985

Age dependent behaviour of red cell glycolytic enzymes in haematological disorders

Jansen, G., Koenderman, L., Rijksen, G., Punt, K., Dekker, A. W. & Staal, G. E., Sep 1985, In : British Journal of Haematology. 61, 1, p. 51-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Agonist and antagonist effects of 3-PPP enantiomers on functional dopamine autoreceptors and postsynaptic dopamine receptors in vitro

Mulder, A. H., Draper, R., Sminia, P., Schoffelmeer, A. N. & Stoof, J. C., 8 Jan 1985, In : European Journal of Pharmacology. 107, 3, p. 291-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review