Research Output

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Meeting Abstract
2020

Updated overall survival (OS) and genomic analysis from a single-arm phase II study of dabrafenib (D) plus trametinib (T) in patients (pts) with BRAF V600E mutant (Mut) metastatic non-small cell lung cancer (NSCLC).

Planchard, D., Besse, B., Groen, H., Hashemi, S., Mazieres, J., Kim, T. M., Quoix, E. A., Souquet, P. J., Barlesi, F., Baik, C. S., Villaruz, L. C., Kelly, R. J., Zhang, S., Tan, M., Gasal, E., Santarpia, L. & Johnson, B. E., 20 May 2020, In : Journal of Clinical Oncology. 38, 15

Research output: Contribution to journalMeeting AbstractAcademic

2019

ADRIATIC: A phase III trial of durvalumab 6 tremelimumab after concurrent chemoradiation for patients with limited stage small cell lung cancer

Senan, S., Shire, N., Mak, G., Yao, W. & Jiang, H., Apr 2019, In : Annals of Oncology. 30, p. 25-25

Research output: Contribution to journalMeeting AbstractAcademic

Assay stability and preanalytics of neurofilament determinations

Willemse, E. & Teunissen, C. E., Sep 2019, In : Multiple Sclerosis Journal. 25, p. 22-22

Research output: Contribution to journalMeeting AbstractAcademic

A TAILOR-MADE EXERCISE PROGRAM DESIGNED FOR IMPROVING CARDIORESPIRATORY FITNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS AND INCREASED CARDIOVASCULAR RISK

van den Hoek, J., van der Esch, M., van der Leeden, M., Lems, W., Metsios, G., Kitas, G. D., Dekker, J., Reimer, W. S. O., Jorstad, H., L'ami, M. J., Heslinga, M. & Nurmohamed, M., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1061-1061

Research output: Contribution to journalMeeting AbstractAcademic

Axonal degeneration as substrate of fractional anisotropy abnormalities in Multiple sclerosis cortex

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., Van de Berg, W. D., Schenk, G., Rocca, M. A., Filippi, M., Geurts, J. & Jonkman, L. E., Jul 2019, In : European Journal of Neurology. 26, p. 107-107

Research output: Contribution to journalMeeting AbstractAcademic

Characterization of brainstem TDP-43 distribution in FTD cases with ALS features

Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436

Research output: Contribution to journalMeeting AbstractAcademic

COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART-BRAIN AXIS: THE ROLE OF CEREBRAL BLOOD FLOW

Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H-P. H. P., Kappelle, J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A., Prins, N. D., Biessels, G. J., Barkhof, F. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P755-P756

Research output: Contribution to journalMeeting AbstractAcademic

Cognitive rehabilitation in patients with advanced progressive multiple sclerosis: possible within limits?

Prouskas, S. E., Chiaravalloti, N. D., Kant, N., Ball, K. K., de Groot, V., Uitdehaag, B. M. J., Geurts, J. J. G., Kooij, E. A. & Hulst, H. E., 10 Sep 2019, (Submitted) In : Multiple Sclerosis Journal. 228.

Research output: Contribution to journalMeeting AbstractAcademic

COGNITIVE SEQUELAE OF RADIOTHERAPY IN LOW-GRADE GLIOMA PATIENTS 26 YEARS AFTER INITIAL DIAGNOSIS: FINAL REPORT

den Otter, P. W. M., Lorenz, L. M. C., Reijneveld, J. C., Hamer, P. C. D. W., Taphoorn, M., Kouwenhoven, M. C. M., Snijders, T., Lie, S. T., Douw, L. & Klein, M., Nov 2019, In : Neuro-Oncology. 21, p. 160-160

Research output: Contribution to journalMeeting AbstractAcademic

COMORBID AMYLOID-β PATHOLOGY AFFECTS NEUROPSYCHIATRIC, NEUROPSYCHOLOGICAL, AND IMAGING FEATURES IN VASCULAR COGNITIVE DISORDERS

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P888-P889

Research output: Contribution to journalMeeting AbstractAcademic

COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA

Macintyre, G., Goranova, T. E., De Silva, D., Ennis, D., Piskorz, A. M., Eldridge, M., Sie, D., Lewsley, L-A., Hanif, A., Wilson, C., Dowson, S., Glasspool, R. M., Lockley, M., Brockbank, E., Montes, A., Walther, A., Sundar, S., Edmondson, R., Hall, G. D., Clamp, A. & 19 others, Gourley, C., Hall, M., Fotopoulou, C., Gabra, H., Paul, J., Supernat, A., Millan, D., Hoyle, A., Bryson, G., Nourse, C., Mincarelli, L., Sanchez, L. N., Ylstra, B., Jimenez-Linan, M., Moore, L., Hofmann, O., Markowetz, F., McNeish, I. A. & Brenton, J. D., Nov 2019, In : Clinical Cancer Research. 25, 22, p. 64-64

Research output: Contribution to journalMeeting AbstractAcademic

Demyelination, Inflammation and Axonal Loss Explain Different Patterns of Fractional Anisotropy Abnormalities in MS Cortical Normal Appearing Gray Matter and Lesions

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., van de Berg, W., Schenk, G., Rocca, M., Filippi, M., Geurts, J. J. G. & Jonkman, L., 9 Apr 2019, In : Neurology. 92, 15

Research output: Contribution to journalMeeting AbstractAcademic

Development of prescribing knowledge and skills of junior doctors in the first year after graduation

Donker, E., Brinkman, D., van den Brink, A. M., Janssen, B., Knol, W., Dumont, G., Jorens, P., Dupont, A., Christiaens, T., Smeden, J., De Waard-Siebinga, I., Peeters, L., Goorden, R., Hessel, M., Richir, M., Van Agtmael, M., Kramers, K. & Tichelaar, J., Jun 2019, In : European Journal of Clinical Pharmacology. 75, p. S58-S58

Research output: Contribution to journalMeeting AbstractAcademic

Diagnostic yield of NGS analysis of a panel of Osteogenesis imperfecta-related genes in 550 patients with Osteogenesis imperfecta, (early-onset) nonsyndromic osteoporosis and related disorders

Maugeri, A., Voorhoeve, E., Appelman-Dijkstra, N. M., van Dijk, A. T. H., van Dijk, F. S., Eekhoff, E. M. W., Elting, M. W., van Haeringen, A., Harsevoort, A., Isrie, M., Janus, G. J. M., de Jongh, R. T., van de Kamp, J. M., van Maarle, M. C., Marcelis, C. L. M., Simon, M. E. H., Simsek, S., Stumpel, C. T. R. M., Terhal, P. A., Veenstra-Knol, H. E. & 6 others, Zillikens, M. C., Meijers-Heijboer, E. J., Sistermans, E. A., Weiss, M. M., Pals, G. & Micha, D., Oct 2019, In : European Journal of Human Genetics. 27, p. 1293-1293

Research output: Contribution to journalMeeting AbstractAcademic

Dose-escalation study of G1T48, an oral selective estrogen receptor degrader (SERD), in postmenopausal women with ER+/HER2- locally advanced or metastatic breast cancer (ABC)

Dees, E. C., Aftimos, P. G., Menke, C. W., De Vries, E. G. E., Neven, P., Pegram, M. D., Iqbal, R., Boers, J., Xiao, J., Sipes, C., Li, C., Sorrentino, J. A., Malik, R. & Beelen, A. P., 1 Oct 2019, In : Annals of Oncology. 30, Supplement 5

Research output: Contribution to journalMeeting AbstractAcademic

Open Access

Factors influencing Autonomy Supportive consultation: a realist review

Kors, JM., Paternotte, E., Martin, L., Verhoeven, C., Schoonmade, L. J., Peerdeman, SM. & Kusurkar, RA., 15 Jan 2019, (Accepted/In press) In : conference abstracts.

Research output: Contribution to journalMeeting AbstractAcademic

FEASIBILITY OF A FIRST PEDIATRIC METABOLITE IN SAFETY TESTING PILOT STUDY USING AN ORAL C-14-MIDAZOLAM MICROTRACER.

van Groen, B. D., van Duijn, E., de Vries, A., Mooij, M. G., Windhorst, A. D., Hendrikse, N. H., Tibboel, D., Vaes, W. H. J. & de Wildt, S. N., Mar 2019, In : Clinical Pharmacology & Therapeutics. 105, p. S38-S38

Research output: Contribution to journalMeeting AbstractAcademic

Geometric efficacy of breath-hold gated MR-guided SABR for adrenal metastases

de Koste, J. V. S., Palacios, M., Bruynzeel, A., Spoelstra, F., Slotman, B., Lagerwaard, F. & Senan, S., Apr 2019, In : Radiotherapy and Oncology. 133, p. S212-S213

Research output: Contribution to journalMeeting AbstractAcademic

Implementing pharmacogenetics by repurposing next generation sequencing data on a personalized card

Santcroos, M. A., Vis, J. K., van der Lee, M., Anvar, S. Y., Kriek, M., Grandia, L., Sie, D. L. S., Cornel, M. C., Bet, P. M. & Swen, J. J., Oct 2019, In : European Journal of Human Genetics. 27, p. 1681-1681

Research output: Contribution to journalMeeting AbstractAcademic

Is SABR Cost-Effective in Oligometastatic Cancer? An Economic Analysis of SABR-Comet

Qu, M. X., Chen, Y., Zaric, G., Senan, S., Olson, R. A., Harrow, S., John-Baptiste, A., Gaede, S., Mulroy, L., Schellenberg, D., Senthi, S., Swaminath, A., Kopek, N., Liu, M., Warner, A., Rodrigues, G., Palma, D. A. & Louie, A. V., 1 Sep 2019, In : International Journal of Radiation Oncology Biology Physics. 105, 1, p. S100-S101

Research output: Contribution to journalMeeting AbstractAcademic

IS SABR COST-EFFECTIVE IN OLIGOMETASTATIC CANCER? AN ECONOMIC ANALYSIS OF SABR-COMET

Qu, M., Chen, Y., Zaric, G., Senan, S., Olson, R., Harrow, S., John-Baptiste, A., Gaede, S., Mulroy, L., Schellenberg, D., Senthi, S., Swaminath, A., Kopek, N., Liu, M., Warner, A., Rodrigues, G., Palma, D. & Louie, A., Oct 2019, In : Radiotherapy and Oncology. 139, p. S41-S42

Research output: Contribution to journalMeeting AbstractAcademic

Kinetics and 28 day test-retest repeatability and reproducibility of [C-11]UCB-J brain PET imaging

Tuncel, H., Boellaard, R., De Vries, E. F. J., Feltes, P. K., Verfaillie, S. C. J., Coomans, E. M., Wolters, E. E., Sweeney, S. P., Ryan, J. M., Ivarsson, M., Lynch, B. A., Schober, P., Scheltens, P., Schuit, R. C., Windhorst, A. D., De Deyn, P. P., van Berckel, B. N. M. & Golla, S. S. V., Oct 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, SUPPL 1, p. S32-S32

Research output: Contribution to journalMeeting AbstractAcademic

Lesion detection by [Zr-89]Zr-DFO-girentuximab and [F-18] FDG-PET in patients with newly diagnosed metastatic renal cell carcinoma

Verhoeff, S., van Es, S. C., Boon, E., van Helden, E., Angus, L., Elias, S. G., Oosting, S. F., Aarntzen, E. H., Brouwers, A. H., Kwee, T. C., Heskamp, S., Hoekstra, O. S., Verheul, H., Zwezerijnen, G. J. C., van Oordt, C. M. D. H., van der Veldt, A. A. M., de Vries, E. G. E., Boerman, O. C., van der Graaf, W. T. A., Oyen, W. J. G. & 1 others, van Herpen, C. M. L., Oct 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, SUPPL 1, p. S67-S67

Research output: Contribution to journalMeeting AbstractAcademic

Live birth rate is higher in primary subfertile women undergoing ICSI with high normal compared to low normal range TSH levels

Delprat, C., Van Dam, E., Van de Ven, P., Aissa, K., Ter Haar, M., Feenstra, Y., De Roos, A., Beelen, G., Schats, R. & Lambalk, C., Jul 2019, In : Human Reproduction. 34, p. 402-403

Research output: Contribution to journalMeeting AbstractAcademic

Local GM Demyelination and Remote Microstructural Damage in Connected WM Tracts both Contribute to Cortical Neurodegeneration in MS

Preziosa, P., Kiljan, S., Jonkman, L., van de Berg, W., Schenk, G., Rocca, M., Filippi, M., Geurts, J. J. G. & Steenwijk, M. D., 9 Apr 2019, In : Neurology. 92, 15

Research output: Contribution to journalMeeting AbstractAcademic

MicroRNA expression profiling predicts clinical outcome in patients with locally advanced larynx and hypopharynx cancer treated with chemoradiotherapy

Poel, D., Rustenburg, F., Sie, D., van Essen, H. F., Eijk, P. P., Bloemena, E., Benites, T. E., Ylstra, B., Ruud, B. H., Leemans, R. C., Buffart, T. E., Verheul, H. M. & Voortman, J., Jul 2019, In : Cancer Research. 79, 13

Research output: Contribution to journalMeeting AbstractAcademic

Molecular genetic, host-derived and clinical determinants of long-term survival in glioblastoma: First results from the ETERNITY study (EORTC 1419).

Weller, M., Reifenberger, G., Le Rhun, E., Clarke, J. L., Soffietti, R., Wick, A., Chinot, O. L., Ducray, F., Hau, P., McDonald, K. L., Marosi, C., Schnell, O., Hottinger, A. F., Reijneveld, J. C., Lombardi, G., Wen, P. Y., Klein, M., Gorlia, T., Felsberg, J. & Hertler, C., 20 May 2019, In : Journal of Clinical Oncology. 37, 15

Research output: Contribution to journalMeeting AbstractAcademic

MR-guided adaptive radiotherapy for intra-abdominal lymphoma

Spoelstra, F., Cobussen, P., Palacios, M., Bruynzeel, A., Lagerwaard, F., Slotman, B. & Senan, S., Apr 2019, In : Radiotherapy and Oncology. 133, p. S30-S31

Research output: Contribution to journalMeeting AbstractAcademic