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2020

The hippo pathway transducers yap1/tead induce acquired resistance to trastuzumab in her2-positive breast cancer

González-Alonso, P., Zazo, S., Martín-Aparicio, E., Luque, M., Chamizo, C., Sanz-Álvarez, M., Minguez, P., Gómez-López, G., Cristóbal, I., Caramés, C., García-Foncillas, J., Eroles, P., Lluch, A., Arpí, O., Rovira, A., Albanell, J., Piersma, S. R., Jimenez, C. R., Madoz-Gúrpide, J. & Rojo, F., May 2020, In : Cancers. 12, 5, 1108.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The image biomarker standardization initiative: Standardized quantitative radiomics for high-throughput image-based phenotyping

Zwanenburg, A., Vallières, M., Abdalah, M. A., Aerts, H. J. W. L., Andrearczyk, V., Apte, A., Ashrafinia, S., Bakas, S., Beukinga, R. J., Boellaard, R., Bogowicz, M., Boldrini, L., Buvat, I., Cook, G. J. R., Davatzikos, C., Depeursinge, A., Desseroit, M. C., Dinapoli, N., Dinh, C. V. & Echegaray, S., 1 May 2020, In : Radiology. 295, 2, p. 328-338 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The pre- and postoperative course of functional status in patients undergoing esophageal cancer surgery

van Egmond, M. A., van der Schaaf, M., Klinkenbijl, J. H. G., Twisk, J. W. R., Engelbert, R. H. H. & van Berge Henegouwen, M. I., Jan 2020, In : European Journal of Surgical Oncology. 46, 1, p. 173-179

Research output: Contribution to journalArticleAcademicpeer-review

The rapidly expanding role of thermal ablation in the treatment of colorectal liver metastases

Meijerink, M. R., van den Tol, M. P. & Puijk, R. S., Aug 2020, In : Hepatobiliary surgery and nutrition. 9, 4, p. 522-525 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series

Agnass, P., van Veldhuisen, E., Vogel, J. A., Kok, H. P., de Keijzer, M. J., Schooneveldt, G., de Haan, L. R., Klaessens, J. H., Scheffer, H. J., Meijerink, M. R., van Lienden, K. P., van Gulik, T. M., Heger, M., Crezee, J. & Besselink, M. G., 13 Apr 2020, In : Translational research : the journal of laboratory and clinical medicine. 5, 3, p. 109-132 24 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts

Putora, P. M., de Ruysscher, D., Glatzer, M., Widder, J., van Houtte, P., Troost, E. G. C., Slotman, B. J., Ramella, S., Pöttgen, C., Peeters, S., Nestle, U., McDonald, F., le Pechoux, C., Dziadziuszko, R., Belderbos, J. & Faivre-Finn, C., 2020, In : Radiotherapy and Oncology. 145, p. 45-48 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of surgery for stage I non-small cell lung cancer in octogenarians in the era of stereotactic body radiotherapy in the Netherlands

de Ruiter, J. C., Heineman, D. J., Daniels, J. M., van Diessen, J. N., Damhuis, R. A. & Hartemink, K. J., Jun 2020, In : Lung Cancer. 144, p. 64-70 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of tumour morphology in assigning HPV status in oropharyngeal squamous cell carcinoma

Molony, P., Werner, R., Martin, C., Callanan, D., Nauta, I., Heideman, DAM., Sheahan, P., Heffron, C. & Feeley, L., 9 Apr 2020, In : Oral Oncology. 105, p. 104670 104670.

Research output: Contribution to journalArticleAcademicpeer-review

The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice

Chomet, M., Schreurs, M., Nguyen, M., Howng, B., Villanueva, R., Krimm, M., Vasiljeva, O., van Dongen, G. A. M. S. & Vugts, D. J., 2020, In : Theranostics. 10, 13, p. 5815-5828 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Third-line Life-prolonging Drug Treatment in a Real-world Metastatic Castration-resistant Prostate Cancer Population: Results from the Dutch Castration-resistant Prostate Cancer Registry

Notohardjo, J. C. L., Kuppen, M. C. P., Westgeest, H. M., van Moorselaar, R. J. A., Mehra, N., Coenen, J. L. L. M., van Oort, I. M., de Vos, A. I., Vervenne, W. L., van den Bergh, A. C. M., Aben, K. K. H., Somford, D. M., Bergman, A. M., Uyl-de Groot, C. A., Gerritsen, W. R. & van den Eertwegh, A. J. M., 1 Jan 2020, (Accepted/In press) In : European Urology Focus.

Research output: Contribution to journalArticleAcademicpeer-review

Time to Diagnosis and Treatment with Palliative Radiotherapy among Inuit Patients with Cancer from the Arctic Territory of Nunavut, Canada

Chan, J., Linden, K., McGrath, C., Renaud, J., Doering, P., MacDonald, S., Gaudet, M., Pantarotto, J. R., Asmis, T., Slotman, B. & Dennis, K., 1 Jan 2020, In : Clinical Oncology. 32, 1, 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Total body irradiation + fludarabine compared to busulfan + fludarabine as “reduced-toxicity conditioning” for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acute Leukemia Working Party of the EBMT

Giebel, S., Labopin, M., Sobczyk-Kruszelnicka, M., Stelljes, M., Byrne, J. L., Fegueux, N., Beelen, D. W., Rovira, M., Spyridonidis, A., Blaise, D., Bornhäuser, M., Karadogan, I., Savani, B. N., Nagler, A., Mohty, M. & Principal investigators of the contributing institutions, 2020, In : Bone Marrow Transplantation.

Research output: Contribution to journalArticleAcademicpeer-review

Total-Body PET and Highly Stable Chelators Together Enable Meaningful 89Zr-Antibody PET Studies up to 30 Days After Injection

Berg, E., Gill, H., Marik, J., Ogasawara, A., Williams, S., van Dongen, G., Vugts, D., Cherry, S. R. & Tarantal, A. F., 1 Mar 2020, In : Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 61, 3, p. 453-460 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of brain metastases in small cell lung cancer: Decision-making amongst a multidisciplinary panel of European experts

Putora, P. M., Fischer, G. F., Früh, M., Califano, R., Faivre-Finn, C., Van Houtte, P., McDonald, F., Nestle, U., Dziadziuszko, R., Le Pechoux, C., Ramella, S., Belderbos, J., Slotman, B. J., Troost, E. G. C., Peeters, S., Widder, J., Pöttgen, C., Reck, M., Blackhall, F., Cappuzzo, F. & 9 others, Besse, B., Novello, S., Garrido, P., Felip, E., O'Brien, M., Paz Ares, L., de Marinis, F., Westeel, V. & De Ruysscher, D., Aug 2020, In : Radiotherapy and Oncology. 149, p. 84-88 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

Qiao, X., van der Zanden, S. Y., Wander, D. P. A., Borràs, D. M., Song, J. Y., Li, X., van Duikeren, S., van Gils, N., Rutten, A., van Herwaarden, T., van Tellingen, O., Giacomelli, E., Bellin, M., Orlova, V., Tertoolen, L. G. J., Gerhardt, S., Akkermans, J. J., Bakker, J. M., Zuur, C. L., Pang, B. & 7 others, Smits, A. M., Mummery, C. L., Smit, L., Arens, R., Li, J., Overkleeft, H. S. & Neefjes, J., 30 Jun 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 15182-15192 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the European PanCareLIFE cohort study

PanCareLIFE Consortium, 1 Oct 2020, In : European Journal of Cancer. 138, p. 212-224

Research output: Contribution to journalArticleAcademicpeer-review

Variation in the implementation of PaTz: a method to improve palliative care in general practice - a prospective observational study

Koper, I., Pasman, H. R. W., Schweitzer, B. P. M., van der Zweep, G., Uyttewaal, G. & Onwuteaka-Philipsen, B. D., 16 Jan 2020, In : BMC Palliative Care. 19, 1, 1 p., 10.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Visual and quantitative evaluation of [18F]FES and [18F]FDHT PET in patients with metastatic breast cancer: an interobserver variability study

Mammatas, L. H., Venema, C. M., Schröder, C. P., de Vet, H. C. W., van Kruchten, M., Glaudemans, A. W. J. M., Yaqub, M. M., Verheul, H. M. W., Boven, E., van der Vegt, B., de Vries, E. F. J., de Vries, E. G. E., Hoekstra, O. S., Hospers, G. A. P. & der Houven van Oordt, C. W. M. V., 1 Jan 2020, In : EJNMMI Research. 10, 1, 40.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion

Benedict, B., van Schie, J. J. M., Oostra, A. B., Balk, J. A., Wolthuis, R. M. F., Riele, H. T. & de Lange, J., 23 Mar 2020, In : Developmental Cell. 52, 6, p. 683-698.e7

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion

van Schie, J. J. M., Faramarz, A., Balk, J. A., Stewart, G. S., Cantelli, E., Oostra, A. B., Rooimans, M. A., Parish, J. L., de Almeida Estéves, C., Dumic, K., Barisic, I., Diderich, K. E. M., van Slegtenhorst, M. A., Mahtab, M., Pisani, F. M., Te Riele, H., Ameziane, N., Wolthuis, R. M. F. & de Lange, J., 27 Aug 2020, In : Nature Communications. 11, 1, p. 4287

Research output: Contribution to journalArticleAcademicpeer-review

What goals do patients and oncologists have when starting a medical treatment for metastatic lung cancer?

Mieras, A., Pasman, HRW., Klop, HT., Onwuteaka-Philipsen, BD., Tarasevych, S. & Tiemessen, M., 11 Aug 2020, In : Clinical Lung Cancer.

Research output: Contribution to journalArticleAcademicpeer-review

White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants

Brugulat-Serrat, A., Salvadó, G., Operto, G., Cacciaglia, R., Sudre, C. H., Grau-Rivera, O., Suárez-Calvet, M., Falcon, C., Sánchez-Benavides, G., Gramunt, N., Minguillon, C., Fauria, K., Barkhof, F., Molinuevo, J. L., Gispert, J. D. & ALFA Study, 1 Apr 2020, In : Human Brain Mapping. 41, 5, p. 1309-1322 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

WHO guide to good prescribing is 25 years old: quo vadis?

Tichelaar, J., Richir, M. C., Garner, S., Hogerzeil, H. & de Vries, T. P. G. M., Jan 2020, In : European Journal of Clinical Pharmacology. 76, 4, 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Whole-genome sequencing of patients with rare diseases in a national health system

NIHR BioResource for the 100,000 Genomes Project, 2 Jul 2020, In : Nature. 583, 7814, p. 96-102 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Working memory moderates the relation between the brain-derived neurotropic factor (BDNF) and psychotherapy outcome for depression

Bruijniks, S. J. E., van Grootheest, G., Cuijpers, P., de Kluiver, H., Vinkers, C. H., Peeters, F., Penninx, B., Teunissen, C. E. & Huibers, M. J. H., 1 Nov 2020, In : Journal of Psychiatric Research. 130, p. 424-432

Research output: Contribution to journalArticleAcademicpeer-review

[89Zr]Zr-rituximab PET/CT activity in patients with therapy refractory interstitial pneumonitis: a feasibility study

Adams, H., van de Garde, E. M., van Moorsel, C. H., Vugts, D. J., van Dongen, G. A. M. S., Grutters, J. C. & Keijsers, R. G., 2019, In : American journal of nuclear medicine and molecular imaging. 9, 6, p. 296-308 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

1-Year Outcomes of Delayed Versus Immediate Intervention in Patients With Transient ST-Segment Elevation Myocardial Infarction

Janssens, GN., van der Hoeven, NW., Lemkes, JS., Everaars, H., van de Ven, PM., Marques, KMJ., Nap, A., van Leeuwen, M. A. H., Appelman, JEA., Knaapen, P., Verouden, CJW., Allaart, CP., Brinckman, S., Saraber, CE., Plomp, K., Timmer, J. R., Kedhi, E., Hermanides, R. S., Meuwissen, M., Schaap, J. & 4 others, Van Der Weerdt, A. P., van Rossum, AC., Nijveldt, R. & van Royen, N., 25 Nov 2019, In : JACC Cardiovascular Interventions. 12, 22, p. 2272-2282 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors

Cascioferro, S., Parrino, B., Petri, G. L., Cusimano, M. G., Schillaci, D., di Sarno, V., Musella, S., Giovannetti, E., Cirrincione, G. & Diana, P., 1 Apr 2019, In : European Journal of Medicinal Chemistry. 167, p. 200-210 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

7T MRI allows detection of disturbed cortical lamination of the medial temporal lobe in patients with Alzheimer's disease

Kenkhuis, B., Jonkman, L. E., Bulk, M., Buijs, M., Boon, B. D. C., Bouwman, F. H., Geurts, J. J. G., van de Berg, W. D. J. & van der Weerd, L., 1 Jan 2019, In : NeuroImage: Clinical. 21, 1 p., 101665.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

89 Zr-immuno-PET: towards a non-invasive clinical tool to measure target engagement of therapeutic antibodies in-vivo

Jauw, Y., o'Donoghue, J., Zijlstra, J., Hoekstra, O., Menke-van der Houven van Oordt, C. W., Morschhauser, F., Carrasquillo, J., Zweegman, S., Pandit-Taskar, N., Lammertsma, A., van Dongen, G., Boellaard, R., Weber, W. & Huisman, M., Dec 2019, In : Journal of Nuclear Medicine. 60, 12, p. 1825-1832

Research output: Contribution to journalArticleAcademicpeer-review

89Zr-labeled bispecific T-cell engager AMG 211 PET shows AMG 211 accumulation in CD3-rich tissues and clear, heterogeneous tumor uptake

Moek, K. L., Waaijer, S. J. H., Kok, I. C., Suurs, F. V., Brouwers, A. H., Menke-van der Houven van Oordt, C. W., Wind, T. T., Gietema, J. A., Schröder, C. P., Mahesh, S. V. K., Jorritsma-Smit, A., Lub-de Hooge, M. N., Fehrmann, R. S. N., de Groot, D. J. A. & de Vries, E. G. E., 2019, In : Clinical Cancer Research. 25, 12, p. 3517-3527

Research output: Contribution to journalArticleAcademicpeer-review

Abstract WMP29: Detection and Segmentation of Subarachnoid Hemorrhages With Deep Learning

Sales Barros, R., van der Steen, W. E., Ponomareva, E., Boers, A. M., Zijlstra, IJ. J., van der Berg, R., Verbaan, D., Vandertop, W. P., Majoie, C. B., Olabarriaga, S. D. & Marquering, H. A., 30 Jan 2019, In : Stroke. 50, Suppl_1

Research output: Contribution to journalArticleAcademicpeer-review

Access to radiotherapy and its association with cancer outcomes in a high-income country: Addressing the inequity in Canada

Chan, J., Polo, A., Zubizarreta, E., Bourque, J-M., Hanna, T. P., Gaudet, M., Dennis, K., Brundage, M., Slotman, B. & Abdel-Wahab, M., Dec 2019, In : Radiotherapy and Oncology. 141, p. 48-55

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Accuracy of computer-assisted surgery in mandibular reconstruction: A postoperative evaluation guideline

van Baar, G. J. C., Liberton, N. P. T. J., Forouzanfar, T., Winters, H. A. H. & Leusink, F. K. J., 2019, In : Oral Oncology. 88, p. 1-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Accuracy of the Delirium Observational Screening Scale (DOS) as a screening tool for delirium in patients with advanced cancer

Neefjes, E. C. W., Van Der Vorst, M. J. D. L., Boddaert, M. S. A., Verdegaal, B. A. T. T., Beeker, A., Teunissen, S. C. C., Beekman, A. T. F., Zuurmond, W. W. A., Berkhof, J. & Verheul, H. M. W., 19 Feb 2019, In : BMC Cancer. 19, 1, 160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

ACE: Absolute Copy number Estimation from low-coverage whole-genome sequencing data

Poell, J. B., Mendeville, M., Sie, D., Brink, A., Brakenhoff, R. H. & Ylstra, B., 15 Aug 2019, In : Bioinformatics. 35, 16, p. 2847-2849

Research output: Contribution to journalArticleAcademicpeer-review

Achieving protein targets without energy overfeeding in critically ill patients: A prospective feasibility study

Looijaard, W. G. P. M., Denneman, N., Broens, B., Girbes, A. R. J., Weijs, P. J. M. & Oudemans-van Straaten, H. M., Dec 2019, In : Clinical Nutrition. 38, 6, p. 2623-2631

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acid sphingomyelinase: No potential as a biomarker for multiple sclerosis

Leurs, C. E., Lopes Pinheiro, M. A., Wierts, L., den Hoedt, S., Mulder, M. T., Eijlers, A. J. C., Schoonheim, M. M., Balk, L. J., Uitdehaag, B. M. J., Killestein, J. & de Vries, H. E., 1 Feb 2019, In : Multiple Sclerosis and Related Disorders. 28, p. 44-49 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

ACRA perfusion study the impact of transradial intervention on digital hand perfusion

van Leeuwen, M. A. H., van der Heijden, D. J., Hollander, M. R., Mulder, M. J., van de Ven, P. M., Ritt, M. J. P. F., Kiemeneij, F., van Mieghem, N. M. & van Royen, N., 1 Apr 2019, In : Circulation. Cardiovascular interventions. 12, 4, e007641.

Research output: Contribution to journalArticleAcademicpeer-review

A cross sectional study on the different domains of frailty for independent living older adults

Verver, D., Merten, H., de Blok, C. & Wagner, C., 1 Mar 2019, In : BMC Geriatrics. 19, 1, 61.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans

van Dinther, D., Lopez Venegas, M., Veninga, H., Olesek, K., Hoogterp, L., Revet, M., Ambrosini, M., Kalay, H., Stöckl, J., van Kooyk, Y. & den Haan, J. M. M., 5 Feb 2019, In : Cancers. 11, 2, 183.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access