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APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms

Charidimou, A., Zonneveld, H. I., Shams, S., Kantarci, K., Shoamanesh, A., Hilal, S., Yates, P. A., Boulouis, G., Na, H. K., Pasi, M., Biffi, A., Chai, Y. L., Chong, J. R., Wahlund, L-O., Clifford, J. R., Chen, C., Gurol, M. E., Goldstein, J. N., Na, D. L., Barkhof, F. & 4 others, Seo, S. W., Rosand, J., Greenberg, S. M. & Viswanathan, A., 23 Jul 2019, In : Neurology. 93, 4, p. e358-e371

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Open Access

A postoperative evaluation guideline for computer-assisted reconstruction of the mandible

van Baar, G. J. C., Liberton, N. P. T. J., Winters, H. A. H., Leeuwrik, L., Forouzanfar, T. & Leusink, F. K. J., Jan 2019, In : Journal of Visualized Experiments. 2020, 155, e60363.

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Open Access

Application of advanced brain positron emission tomography–based molecular imaging for a biological framework in neurodegenerative proteinopathies

Perani, D., Iaccarino, L., Jacobs, A. H., Lammertsma, A. A., Nordberg, A., Windhorst, A. D., Gerhard, A., Winkeler, A., Gee, A., Kuhnast, B., Halldin, C., Brooks, D., Rodriguez-Vieitez, E., Turkheimer, F. E., López-Picón, F., Knudsen, G. M., Vercouillie, J., Rinne, J. O., Herholz, K., van Laere, K. & 11 others, Santiago-Ribeiro, M. J., Herth, M. M., Carroll, M. A., Bottlaender, M., Hansson, O., Edison, P., Hinz, R., Boellaard, R., Moresco, R. M., Pappata, S. & IMBI Brain Imaging Working Group, 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 327-332

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Open Access

Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis

Eshaghi, A., Kievit, R. A., Prados, F., Sudre, C. H., Nicholas, J., Cardoso, M. J., Chan, D., Nicholas, R., Ourselin, S., Greenwood, J., Thompson, A. J., Alexander, D. C., Barkhof, F., Chataway, J. & Ciccarelli, O., 28 May 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 22, p. 11020-11027 8 p.

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Applying the ATN scheme in a memory clinic population: The ABIDE project

Altomare, D., de Wilde, A., Ossenkoppele, R., Pelkmans, W., Bouwman, F., Groot, C., van Maurik, I., Zwan, M., Yaqub, M., Barkhof, F., van Berckel, B. N., Teunissen, C. E., Frisoni, G. B., Scheltens, P. & van der Flier, W. M., 22 Oct 2019, In : Neurology. 93, 17, p. e1635-e1646

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Approach to the Older Adult With Multiple Myeloma

Mina, R., Bringhen, S., Wildes, T. M., Zweegman, S. & Rosko, A. E., Jan 2019, In : American Society of Clinical Oncology educational book. 39, p. 500-518 19 p.

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Appropriate antibiotic prescribing among final-year medical students in Europe

van der Voort, T., Brinkman, D. J., Benemei, S., Böttiger, Y., Chamontin, B., Christiaens, T., Likic, R., Mačiulaitis, R., Marandi, T., Monteiro, E. C., Papaioannidou, P., Pers, Y. M., Pontes, C., Raskovic, A., Regenthal, R., Sanz, E. J., Wilson, K., Tichelaar, J., van Agtmael, M. A. & Working Group Research on CPT Education of the European Association for Clinical Pharmacology and Therapeutics (EACPT), 1 Sep 2019, In : International Journal of Antimicrobial Agents. 54, 3, p. 375-379

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A pragmatist approach to clinical ethics support: overcoming the perils of ethical pluralism

Inguaggiato, G., Metselaar, S., Porz, R. & Widdershoven, G., 15 Sep 2019, In : Medicine, Health Care and Philosophy. 22, 3, p. 427-438 12 p.

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A preschool-based intervention for Early Childhood Education and Care (ECEC) teachers in promoting healthy eating and physical activity in toddlers: Study protocol of the cluster randomized controlled trial PreSchool@HealthyWeight

Toussaint, N., Streppel, M. T., Mul, S., Schreurs, A., Balledux, M., van Drongelen, K., Janssen, M., Fukkink, R. G. & Weijs, P. J. M., 7 Mar 2019, In : BMC Public Health. 19, 1, 278.

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A qualitative study investigating the meaning of participation to improve the measurement of this construct

de Wind, A., van der Beek, A. J., Boezeman, E. J., Swenneker, R., Anema, J. R., de Boer, A. G. E. M., Beckerman, H., Hoving, J. L., Nieuwenhuijsen, K., Scharn, M., Stam, M., Terwee, C. B., Frings-Dresen, M. H. W. & Tamminga, S. J., 15 Aug 2019, In : Quality of Life Research. 28, 8, p. 2233-2246 14 p.

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A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

Nutma, E., Stephenson, J. A., Gorter, R. P., de Bruin, J., Boucherie, D. M., Donat, C. K., Breur, M., van der Valk, P., Matthews, P. M., Owen, D. R. & Amor, S., 1 Nov 2019, In : Brain : a journal of neurology. 142, 11, p. 3440-3455 16 p.

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Are Dutch dental students and dental-care providers competent prescribers of drugs?

Brinkman, D. J., Nijland, N., van Diermen, D. E., Bruers, J. J. M., Ligthart, W. S. M., Rietveld, P. J., Tams, J., Vissink, A., Wilhelm, A. J., Rozema, F. R., Tichelaar, J. & van Agtmael, M. A., 10 Dec 2019, In : European Journal of Oral Sciences. 127, 6, p. 531-538

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A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project

Kerr, K. M., Thunnissen, E., Dafni, U., Finn, S. P., Bubendorf, L., Soltermann, A., Verbeken, E., Biernat, W., Warth, A., Marchetti, A., Speel, E-J. M., Pokharel, S., Quinn, A. M., Monkhorst, K., Navarro, A., Madsen, L. B., Radonic, T., Wilson, J., de Luca, G., Gray, S. G. & 17 others, Cheney, R., Savic, S., Martorell, M., Muley, T., Baas, P., Meldgaard, P., Blackhall, F., Dingemans, A-M., Dziadziuszko, R., Vansteenkiste, J., Weder, W., Polydoropoulou, V., Geiger, T., Kammler, R., Peters, S., Stahel, R. & Lungscape Consortium, 1 May 2019, In : Lung Cancer. 131, p. 95-103

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Artificial intelligence: Power for civilisation - And for better healthcare

Horgan, D., Romao, M., Morré, S. A. & Kalra, D., 13 Dec 2019, In : Public Health Genomics.

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Open Access

Asciminib in chronic myeloid leukemia after Abl kinase inhibitor failure

Hughes, T. P., Mauro, M. J., Cortes, J. E., Minami, H., Rea, D., DeAngelo, D. J., Breccia, M., Goh, Y-T., Talpaz, M., Hochhaus, A., Coutre, P. L., Ottmann, O., Heinrich, M. C., Steegmann, J. L., Deininger, M. W. N., Janssen, J. J. W. M., Mahon, F-X., Minami, Y., Yeung, D., Ross, D. M. & 10 others, Tallman, M. S., Park, J. H., Druker, B. J., Hynds, D., Duan, Y., Meille, C., Hourcade-Potelleret, F., Vanasse, K. G., Lang, F. & Kim, D-W., 2019, In : New England Journal of Medicine. 381, 24, p. 2315-2326

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A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Dorlo, T. P. C., Janssen, J., Niewerth, D., Wilhelm, A. J., Zwaan, C. M., Beijnen, J. H., Attarbaschi, A., Baruchel, A., Fagioli, F., Klingebiel, T., de Moerloose, B., Palumbo, G., von Stackelberg, A., Kaspers, G. J. L. & Huitema, A. D. R., 16 Jul 2019, In : Clinical Pharmacokinetics.

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Open Access

ASO Author Reflections: Advanced Imaging Allows Better Detection of Peritoneal Metastases

Sluiter, N. R. & Tuynman, J. B., 15 Jan 2019, In : Annals of Surgical Oncology. 26, 1, p. 165-166 2 p.

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Assessing the Pre-Analytical Stability of Small-Molecule Metabolites in Cerebrospinal Fluid Using Direct-Infusion Metabolomics

Haijes, H. A., Willemse, E. A. J., Gerrits, J., van der Flier, W. M., Teunissen, C. E., Verhoeven-Duif, N. M. & Jans, J. J. M., 1 Oct 2019, In : Metabolites. 9, 10, 236.

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Open Access

Assessment of herd effects among women and heterosexual men after girls-only HPV16/18 vaccination in the Netherlands: A repeated cross-sectional study

Woestenberg, P. J., Bogaards, J. A., King, A. J., Leussink, S., van der Sande, M. A. B., Hoebe, C. J. PA., van Benthem, B. H. B. & on behalf of the Medical Microbiological Laboratories and the Public Health Services, 1 Jun 2019, In : International Journal of Cancer. 144, 11, p. 2718-2727

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Assessment of Neurocognitive Impairment and Speech Functioning before Head and Neck Cancer Treatment

Piai, V., Prins, J. B., Verdonck-de Leeuw, I. M., Leemans, C. R., Terhaard, C. H. J., Langendijk, J. A., Baatenburg de Jong, R. J., Smit, J. H., Takes, R. P. & Kessels, R. P. C., 1 Mar 2019, In : JAMA Otolaryngology - Head and Neck Surgery. 145, 3, p. 251-257

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Assessment of simplified methods for quantification of 18F-FDHT uptake in patients with metastatic castration-resistant prostate cancer

Kramer, G. M., Yaqub, M., Vargas, H. A., Schuit, R. C., Windhorst, A. D., van den Eertwegh, A. J. M., van der Veldt, A. A. M., Bergman, A. M., Burnazi, E. M., Lewis, J. S., Chua, S., Staton, K. D., Beattie, B. J., Humm, J. L., Davis, I. D., Weickhardt, A. J., Scott, A. M., Morris, M. J., Hoekstra, O. S. & Lammertsma, A. A., 1 Sep 2019, In : Journal of Nuclear Medicine. 60, 9, p. 1221-1227

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Association Between Black Race and Presentation and Liver-Related Outcomes of Patients With Autoimmune Hepatitis

de Boer, Y. S., Gerussi, A., van den Brand, F. F., Wong, G-W., Halliday, N., Liberal, R., Drenth, J. P. H., Thorburn, D., Bouma, G., Dutch Autoimmune Hepatitis Study group, van Gerven, N. M., Beuers, U., van Erpecum, K. J., van Buuren, H. R., den Ouden, J. W., Brouwer, J. T., Vrolijk, J. M., Verdonk, R. C., van Hoek, B., Koek, G. H. & 13 others, Guichelaar, M. M. J., Bloemena, E., van Nieuwkerk, C. M. J., Schreuder, T. C. M. A., van der Wouden, E. J., van Meyel, J. J. M., Baak, L. C., Stadhouders, P. H. G. M., Klemt-Kropp, M., Verhagen, M. A. M. T., Bhalla, A., Kuijvenhoven, J. P. & Heneghan, M. A., 1 Jul 2019, In : Clinical Gastroenterology and Hepatology. 17, 8, p. 1616-1624.e2

Research output: Contribution to journalArticleAcademicpeer-review

Association between Pembrolizumab-related Adverse Events and Treatment Outcome in Advanced Melanoma: Results from the Dutch Expanded Access Program

Bisschop, C., Wind, T. T., Blank, C. U., Koornstra, R. H. T., Kapiteijn, E., van den Eertwegh, A. J. M., de Groot, J. W. B., Jalving, M. & Hospers, G. A. P., 2019, In : Journal of Immunotherapy. 42, 6, p. 208-214

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Association between tumor location and neurocognitive functioning using tumor localization maps

Habets, E. J. J., Hendriks, E. J., Taphoorn, M. J. B., Douw, L., Zwinderman, A. H., Vandertop, W. P., Barkhof, F., de Witt Hamer, P. C. & Klein, M., 1 Sep 2019, In : Journal of Neuro-Oncology. 144, 3, p. 573-582

Research output: Contribution to journalArticleAcademicpeer-review

Association of a Multifaceted Intervention With Ordering of Unnecessary Laboratory Tests Among Caregivers in Internal Medicine Departments

Bindraban, R. S., van Beneden, M., Kramer, M. H. H., van Solinge, W. W., van de Ven, P. M., Naaktgeboren, C. A., Al-Dulaimy, M., van der Wekken, L. C., Bandt, Y. C., Stam, F., Neppelenbroek, S. I. M., Griffioen-Keijzer, A., Castelijn, D. A. R., Wevers, B. A., Boerman, A. W., van Wijnen, M., Ten Berg, M. J. & Nanayakkara, P. W. B., 26 Jul 2019, In : JAMA network open. 2, 7, e197577.

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Open Access

Association of Rituximab Treatment with Disability Progression among Patients with Secondary Progressive Multiple Sclerosis

Naegelin, Y., Naegelin, P., von Felten, S., Lorscheider, J., Sonder, J., Uitdehaag, B. M. J., Scotti, B., Zecca, C., Gobbi, C., Kappos, L. & Derfuss, T., Mar 2019, In : JAMA Neurology. 76, 3, p. 274-281

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Associations between overweight and mental health problems among adolescents, and the mediating role of victimization

van Vuuren, C. L., Wachter, G. G., Veenstra, R., Rijnhart, J. J. M., van der Wal, M. F., Chinapaw, M. J. M. & Busch, V., 2019, In : BMC Public Health. 19, 1, 612.

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Open Access

Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia

Løhmann, D. J. A., Asdahl, P. H., Abrahamsson, J., Ha, S-Y., Jónsson, Ó. G., Kaspers, G. J. L., Koskenvuo, M., Lausen, B., de Moerloose, B., Palle, J., Zeller, B., Sung, L. & Hasle, H., 1 Nov 2019, In : Cancer Medicine. 8, 15, p. 6634-6643 10 p.

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Open Access

Associations of AD biomarkers and cognitive performance with nutritional status: The NUDAD project

Doorduijn, A. S., Visser, M., van de Rest, O., Kester, M. I., de Leeuw, F. A., Boesveldt, S., Fieldhouse, J. L. P., van den Heuvel, E. G. H. M., Teunissen, C. E., Scheltens, P., van der Flier, W. M. & de van der Schueren, M. A. E., 1 May 2019, In : Nutrients. 11, 5, 1161.

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Astrocyte Subtype Vulnerability in Stem Cell Models of Vanishing White Matter

Leferink, P. S., Dooves, S., Hillen, A. E. J., Watanabe, K., Jacobs, G., Gasparotto, L., Cornelissen-Steijger, P., van der Knaap, M. S. & Heine, V. M., 1 Nov 2019, In : Annals of Neurology. 86, 5, p. 780-792 13 p.

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Astrocytic ceramide as possible indicator of neuroinflammation

de Wit, N. M., den Hoedt, S., Martinez-Martinez, P., Rozemuller, A. J., Mulder, M. T. & de Vries, H. E., 25 Feb 2019, In : Journal of Neuroinflammation. 16, 1, 48.

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Open Access

A two-gene methylation signature for the diagnosis of bladder cancer in urine

Bosschieter, J., Nieuwenhuijzen, J. A., Hentschel, A., van Splunter, A. P., Segerink, L. I., Vis, A. N., Wilting, S. M., Lissenberg-Witte, B. I., A van Moorselaar, R. J. & Steenbergen, R. D., Feb 2019, In : Epigenomics. 11, 3, p. 337-347 11 p.

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Autologous activated fibrin sealant for the esophageal anastomosis: a feasibility study

Plat, V. D., Bootsma, B. T., van der Wielen, N., van der Peet, D. L. & Daams, F., 2019, In : Journal of Surgical Research. 234, p. 49-53

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Automated fiber tract reconstruction for surgery planning: Extensive validation in language-related white matter tracts

Mancini, M., Vos, S. B., Vakharia, V. N., O'Keeffe, A. G., Trimmel, K., Barkhof, F., Dorfer, C., Soman, S., Winston, G. P., Wu, C., Duncan, J. S., Sparks, R. & Ourselin, S., 1 Jan 2019, In : NeuroImage: Clinical. 23, 101883.

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Open Access

Autosomal dominant Marfan syndrome caused by a previously reported recessive FBN1 variant

Overwater, E., Efrat, R., Barge-Schaapveld, D. Q. C. M., Lakeman, P., Weiss, M. M., Maugeri, A., van Tintelen, J. P. & Houweling, A. C., Feb 2019, In : Molecular Genetics and Genomic Medicine. 7, 2, e00518.

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Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., van de Berg, W. D. J., Schenk, G. J., Rocca, M. A., Filippi, M., Geurts, J. J. G. & Jonkman, L. E., 1 Jul 2019, In : Brain. 142, 7, p. 1921-1937

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Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients

Huls, G., Chitu, D. A., Havelange, V., Jongen-Lavrencic, M., van de Loosdrecht, A. A., Biemond, B. J., Sinnige, H., Hodossy, B., Graux, C., Kooy, R. V. M., de Weerdt, O., Breems, D., Klein, S., Kuball, J. R., Deeren, D., Terpstra, W., Vekemans, M-C., Ossenkoppele, G. J., Vellenga, E., Löwenberg, B. & 1 others, Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON), 1 Jan 2019, In : Blood. 133, 13, p. 1457-1464 8 p.

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Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

Liebsch, F., Kulic, L., Teunissen, C., Shobo, A., Ulku, I., Engelschalt, V., Hancock, M. A., van der Flier, W. M., Kunach, P., Rosa-Neto, P., Scheltens, P., Poirier, J., Saftig, P., Bateman, R. J., Breitner, J., Hock, C. & Multhaup, G., 1 Dec 2019, In : Nature Communications. 10, 1, 2240.

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