Research Output 1986 2019

2003

Beïnvloeding van de farmacokinetiek en de farmacodynamiek: Op de IC liggen geen gewone patiënten

Swart, E. L. & Girbes, A. R. J., 27 Jun 2003, In : Pharmaceutisch Weekblad. 138, 26, p. 916-922 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

CKD-602 Chong Kun Dang

Crul, M., 1 Dec 2003, In : Current Opinion in Investigational Drugs. 4, 12, p. 1455-1459 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin

Crul, M., Van Waardenburg, R. C. A. M., Bocxe, S., Van Eijndhoven, M. A. J., Pluim, D., Beijnen, J. H. & Schellens, J. H. M., 15 Jan 2003, In : Biochemical Pharmacology. 65, 2, p. 275-282 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Gebruik door nederlandse kinderen en ervaringen van ouders: Methylfenidaat rukt onstuitbaar op

Faher, A., Hugtenburg, J., Schirm, E., De Boer, I., Tobi, H. & Heerdink, R., 14 Mar 2003, In : Pharmaceutisch Weekblad. 138, 11, p. 374-378 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inhalatiecorticosteroïden bij COPD: Niet of slechts beperkt werkzaam

Hugtenburg, J. G., Paltantewari, Y. & Menckeberg, T. T., 1 Aug 2003, In : Pharmaceutisch Weekblad. 138, 31, p. 1094-1099 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Measurement of 18F-FDG concentrations in blood samples: Comparison of direct calibration and standard solution methods

Greuter, H. N. J. M., Boellaard, R., Van Lingen, A., Franssen, E. J. F. & Lammertsma, A. A., 1 Dec 2003, In : Journal of Nuclear Medicine Technology. 31, 4, p. 206-209 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Onttrekkingsverschinjnselen bij SSRI's: Kennis inzetten tegen ongerusthied

Stolk, P., Hugtenburg, J. & Egberts, T., 14 Nov 2003, In : Pharmaceutisch Weekblad. 138, 46, p. 1607-1612 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quantitative assessment of P-glycoprotein function in the rat blood-brain barrier by distribution volume of [11C]verapamil measured with PET

Bart, J., Willemsen, A. T. M., Groen, H. J. M., Van Der Graaf, W. T. A., Wegman, T. D., Vaalburg, W., De Vries, E. G. E. & Hendrikse, N. H., 1 Jan 2003, In : NeuroImage. 20, 3, p. 1775-1782 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Randomized phase I clinical and pharmacologic study of weekly versus twice-weekly dose-intensive cisplatin and gemcitabine in patients with advanced non-small cell lung cancer

Crul, M., Schoemaker, N. E., Pluim, D., Maliepaard, M., Underberg, R. W. M., Schot, M., Sparidans, R. W., Baas, P., Beijnen, J. H., Van Zandwijk, N. & Schellens, J. H. M., 1 Oct 2003, In : Clinical Cancer Research. 9, 10 I, p. 3526-3533 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE

Ledeboer, A., Wierinckx, A., Bol, J. G. J. M., Floris, S., Renardel de Lavalette, C., De Vries, H. E., van den Berg, T. K., Dijkstra, C. D., Tilders, F. J. H. & van dam, A-M., Mar 2003, In : Journal of Neuroimmunology. 136, 1-2, p. 94-103 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Safety, biodistribution, pharmacokinetics, and immunogenicity of 99mTc-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with squamous cell carcinoma of the head and neck

Colnot, D. R., Roos, J. C., De Bree, R., Wilhelm, A. J., Kummer, J. A., Hanft, G., Heider, K. H., Stehle, G., Snow, G. B. & Van Dongen, G. A. M. S., 1 Sep 2003, In : Cancer Immunology, Immunotherapy. 52, 9, p. 576-582 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Spin in het web

Dik, E. & Hugtenburg, J. G., 6 Jun 2003, In : Pharmaceutisch Weekblad. 138, 23, 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

2002

An oncological view on the blood-testis barrier

Bart, J., Groen, H. J. M., Van Der Graaf, W. T. A., Hollema, H., Hendrikse, N. H., Vaalburg, W., Sleijfer, D. T. & De Vries, E. G. E., 1 Jan 2002, In : Lancet Oncology. 3, 6, p. 357-363 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Blijvende aandacht

Hugtenburg, J. G. & Beckeringh, J. J., 4 Jan 2002, In : Pharmaceutisch Weekblad. 137, 1, 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Clinical pharmacokinetics, pharmacodynamics and metabolism of the novel matrix metalloproteinase inhibitor ABT-518

Crul, M., Beerepoot, L. V., Stokvis, E., Vermaat, J. S. P., Rosing, H., Beijnen, J. H., Voest, E. E. & Schellens, J. H. M., 19 Dec 2002, In : Cancer Chemotherapy and Pharmacology. 50, 6, p. 473-478 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

DNA-based drug interactions of cisplatin

Crul, M., van Waardenburg, R. C. A. M., Beijnen, J. H. & Schellens, J. H. M., 1 Jan 2002, In : Cancer Treatment Reviews. 28, 6, p. 291-303 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Dynamics of multidrug resistance: P-glycoprotein analyses with positron emission tomography

Hendrikse, N. H. & Vaalburg, W., 14 Oct 2002, In : Methods. 27, 3, p. 228-233 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epidemiologie van ziekten en gebruik van receptgeneesmiddelen bij kinderen: Wat hebben en gebruiken onze kleine klantjes?

Van de Vijver, D. A. M. C., Hugtenburg, J. G. & De Boer, A., 3 May 2002, In : Pharmaceutisch Weekblad. 137, 18, p. 639-643 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epilepsie bij kinderen: De behandeling van verschillende syndromen

Leyten, C. C. M., Hugtenburg, J. G., Bok, L. A. & Schobben, A. F. A. M., 7 Jun 2002, In : Pharmaceutisch Weekblad. 137, 23, p. 844-848 5 p.

Research output: Contribution to journalShort surveyAcademicpeer-review

Evaluation of the bioequivalence of tablets and capsules containing the novel anticancer agent R115777 (Zarnestra) in patients with advanced solid tumors

Crul, M., De Klerk, G. J., Swart, M., Weiner, L., Palmer, P. A., Bol, C. J., Beijnen, J. H. & Schellens, J. H. M., 1 Jan 2002, In : European Journal of Drug Metabolism and Pharmacokinetics. 27, 1, p. 61-65 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evenredig veel aandacht

Hugtenburg, J., 7 Jun 2002, In : Pharmaceutisch Weekblad. 137, 23, 1 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells

Ledeboer, A., Brevé, J. J. P., Wierinckx, A., van der Jagt, S., Bristow, A. F., Leysen, J. E., Tilders, F. J. H. & Van Dam, A-M., Oct 2002, In : European Journal of Neuroscience. 16, 7, p. 1175-85 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fully automated high yield synthesis of (R)- and (S)-[11C]verapamil for measuring P-glycoprotein function with positron emission tomography

Luurtsema, G., Windhorst, A. D., Mooijer, M. P. J., Herscheid, J. D. M., Lammertsma, A. A. & Franssen, E. J. F., 1 Dec 2002, In : Journal of Labelled Compounds and Radiopharmaceuticals. 45, 14, p. 1199-1207 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Geneesmiddelprofiel: Tobramycine (TOBI®)

Beckeringh, J. J. & Hugtenburg, J. G., 8 Nov 2002, In : Pharmaceutisch Weekblad. 137, 45, p. 1590-1594 5 p.

Research output: Contribution to journalShort surveyAcademicpeer-review

Imaging of P glycoprotein function in vivo with PET

Hendrikse, N. H. & Vaalburg, W., 1 Dec 2002, In : Novartis Foundation Symposium. 243, p. 137-148 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Isocratic ion-exchange chromatographic assay for the nucleotide gemcitabine triphosphate in human white blood cells

Sparidans, R. W., Crul, M., Schellens, J. H. M. & Beijnen, J. H., 25 Nov 2002, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 780, 2, p. 423-430 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Phase I and pharmacological study of daily oral administration of perifosine (D-21266) in patients with advanced solid tumours

Crul, M., Rosing, H., De Klerk, G. J., Dubbelman, R., Traiser, M., Reichert, S., Knebel, N. G., Schellens, J. H. M., Beijnen, J. H. & Ten Bokkel Huinink, W. W., 23 Aug 2002, In : European Journal of Cancer. 38, 12, p. 1615-1621 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Phase I clinical and pharmacologic study of chronic oral administration of the farnesyl protein transferase inhibitor R115777 in advanced cancer

Crul, M., de Klerk, G. J., Swart, M., van't Veer, L. J., de Jong, D., Boerrigter, L., Palmer, P. A., Bol, C. J., Tan, H., de Gast, G. C., Beijnen, J. H. & Schellens, J. H. M., 1 Jun 2002, In : Journal of Clinical Oncology. 20, 11, p. 2726-2735 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Population pharmacokinetics of the novel anticancer agent KRN7000

Crul, M., Mathôt, R. A., Giaccone, G., Punt, C. J., Rosing, H., Hillebrand, M. J., Ando, Y., Nishi, N., Tanaka, H., Schellens, J. H. & Beijnen, J. H., 6 Apr 2002, In : Cancer Chemotherapy and Pharmacology. 49, 4, p. 287-293 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Psychofarmaca bij kinderen: Eén aanpak, naast andere

Hugtenburg, J. G., 7 Jun 2002, In : Pharmaceutisch Weekblad. 137, 23, p. 839-842 4 p.

Research output: Contribution to journalShort surveyAcademicpeer-review

Site-specific modulation of LPS-induced fever and interleukin-1 beta expression in rats by interleukin-10

Ledeboer, A., Binnekade, R., Brevé, J. J. P., Bol, J. G. J. M., Tilders, F. J. H. & Van Dam, A-M., Jun 2002, In : American Journal of Physiology. Regulatory Integrative and Comparative Physiology. 282, 6, p. R1762-72

Research output: Contribution to journalArticleAcademicpeer-review

Studies met positronemissietomografie. Multidrugresistentie gevisualiseerd

Hendrikse, N. H., Vaalburg, W., De Vries, E. G. E. & Rutten, W. J. M. J., 19 Jul 2002, In : Pharmaceutisch Weekblad. 137, 29, p. 1041-1043 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001

A single administration of interleukin-1 or amphetamine induces long-lasting increases in evoked noradrenaline release in the hypothalamus and sensitization of ACTH and corticosterone responses in rats

Schmidt, E. D., Schoffelmeer, A. N. M., De Vries, T. J., Wardeh, G., Dogterom, G., Bol, J. G. J. M., Binnekade, R. & Tilders, F. J. H., 26 Jun 2001, In : European Journal of Neuroscience. 13, 10, p. 1923-1930 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bewegingsstoornissen door geneesmiddelen: Staken of vervangen is de beste opplossing

Hugtenburg, J. G., 9 Feb 2001, In : Pharmaceutisch Weekblad. 136, 6, p. 202-207 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Een nieuwe klasse oncolytica

Crul, M., Underberg, R. W. M., Beijnen, J. H. & Schellens, J. H. M., 23 Feb 2001, In : Pharmaceutisch Weekblad. 136, 8, p. 260-265 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Eerste en tweede uitgifte van geneesmiddelen: Zinvolle actie ann de balie

Hugtenburg, J. G., Blom, A. T. G. & Gopie, C. T. W., 26 Oct 2001, In : Pharmaceutisch Weekblad. 136, 43, p. 1612-1613 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Expression of interleukin-1 beta in rat dorsal root ganglia

Copray, J. C., Mantingh, I., Brouwer, N., Biber, K., Küst, B. M., Liem, R. S., Huitinga, I., Tilders, F. J., Van Dam, A. M. & Boddeke, H. W., 30 Aug 2001, In : Journal of Neuroimmunology. 118, 2, p. 203-11 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

HIV bij kinderen. De eerste klap is een daalder waard

Gast, M. C. W. & Hugtenburg, J. G., 28 Sep 2001, In : Pharmaceutisch Weekblad. 136, 39, p. 1456-1461 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vivo measurement of [11C]verapamil kinetics in human tissues

Hendrikse, N. H., De Vries, E. G. E., Franssen, E. J. F., Vaalburg, W. & Van Der Graaf, W. T. A., 1 Dec 2001, In : European Journal of Clinical Pharmacology. 56, 11, p. 827-829 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

P-glycoprotein at the blood-brain barrier and analysis of drug transport with positron-emission tomography

Hendrikse, N. H., Bart, J., De Vries, E. G. E., Groen, H. J. M., Van Der Graaf, W. T. A. & Vaalburg, W., 1 Jan 2001, In : Journal of Clinical Pharmacology. 41, 7 SUPPL.

Research output: Contribution to journalArticleAcademicpeer-review

Radioimmunotherapy in patients with head and neck squamous cell carcinoma: Initial experience

Colnot, D. R., Quak, J. J., Roos, J. C., de Bree, R., Wilhelm, A. J., Snow, G. B. & van Dongen, G. A. M. S., 1 Jan 2001, In : Head and Neck. 23, 7, p. 559-565 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ras biochemistry and farnesyl transferase inhibitors: A literature survey

Crul, M., De Klerk, G. J., Beijnen, J. H. & Schellens, J. H. M. S., 17 Apr 2001, In : Anti-Cancer Drugs. 12, 3, p. 163-184 22 p.

Research output: Contribution to journalLiterature reviewAcademicpeer-review

Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometry

Crul, M., Van Den Bongard, H. J. G. D., Tibben, M. M., Van Tellingen, O., Sava, G., Schellens, J. H. M. & Beijnen, J. H., 1 Mar 2001, In : Analytical and Bioanalytical Chemistry. 369, 5, p. 442-445 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

2000

Amphotericin B colloidal dispersion (Amphocil) vs fluconazole for the prevention of fungal infections in neutropenic patients: Data of a prematurely stopped clinical trial

Timmers, G. J., Zweegman, S., Simoons-Smit, A. M., Van Loenen, A. C., Touw, D. & Huijgens, P. C., 2000, In : Bone Marrow Transplantation. 25, 8, p. 879-884 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Enhanced cerebral uptake of receptor ligands by modulation of P- glycoprotein function in the blood-brain barrier

Doze, P., Van Waarde, A., Elsinga, P. H., Hendrikse, N. H. & Vaalburg, W., 16 Mar 2000, In : SYNAPSE. 36, 1, p. 66-74 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vivo delineation of 5-HT(1A) receptors in human brain with [18F]MPPF

Passchier, J., Van Waarde, A., Pieterman, R. M., Elsinga, P. H., Pruim, J., Hendrikse, H. N., Willemsen, A. T. M. & Vaalburg, W., 22 Nov 2000, In : Journal of Nuclear Medicine. 41, 11, p. 1830-1835 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipopolysaccharide transport from the peritoneal cavity to the blood: is it controlled by the vagus nerve?

Romanovsky, A. A., Ivanov, A. I., Lenczowski, M. J., Kulchitsky, V. A., Van Dam, A. M., Poole, S., Homer, L. D. & Tilders, F. J., 20 Dec 2000, In : Autonomic neuroscience : basic & clinical. 85, 1-3, p. 133-40 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Monitoring interactions at ATP-dependent drug efflux pumps

Hendrikse, N. H., 1 Jan 2000, In : Current Pharmaceutical Design. 6, 16, p. 1653-1668 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Phase I therapy study of 186re-labeled chimeric monoclonal antibody U36 in patients with squamous cell carcinoma of the head and neck

Colnot, D. R., Quak, J. J., Roos, J. C., Van Lingen, A., Wilhelm, A. J., Van Kamp, G. J., Huijgens, P. C., Snow, G. B. & Van Dongen, G. A. M. S., 1 Dec 2000, In : Journal of Nuclear Medicine. 41, 12, p. 1999-2010 12 p.

Research output: Contribution to journalArticleAcademicpeer-review