Hematology laboratory

Research Output 1989 2019

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Letter
2018

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Franssen, L. E., Nijhof, I. S., Couto, S., Levin, M. D., Bos, G. M. J., Broijl, A., Klein, S. K., Ren, Y., Wang, M., Koene, H. R., Bloem, A. C., Beeker, A., Faber, L. M., van der Spek, E., Raymakers, R., Leguit, R. J., Sonneveld, P., Zweegman, S., Lokhorst, H., Mutis, T. & 3 othersThakurta, A., Qian, X. & van de Donk, N. W. C. J., 31 Jul 2018, In : Haematologica. 103, 8, p. e368-e371

Research output: Contribution to journalLetterAcademicpeer-review

Open Access
2012

Application of cultured human regulatory T cells requires preclinical in vivo evaluation

Vercoulen, Y., Guichelaar, T., Meerding, J., Emmelot, M., Pingen, M., Storm, G., Coffer, P., Sawitzki, B., Martens, A., Mutis, T. & Prakken, B., 1 Mar 2012, In : Journal of Allergy and Clinical Immunology. 129, 3

Research output: Contribution to journalLetterAcademicpeer-review

2011

The therapeutic human CD38 antibody daratumumab improves the anti-myeloma effect of newly emerging multi-drug therapies

Van Der Veer, M. S., De Weers, M., Van Kessel, B., Bakker, J. M., Wittebol, S., Parren, P. W. H. I., Lokhorst, H. M. & Mutis, T., 1 Oct 2011, In : Blood cancer journal. 1, 10, e41.

Research output: Contribution to journalLetterAcademicpeer-review

2010

Graft-versus-host driven graft-versus-leukemia effect of minor histocompatibility antigen HA-1 in chronic myeloid leukemia patients

Mutis, T., Brand, R., Gallardo, D., Van Biezen, A., Niederwieser, D. & Goulmy, E., 1 Jan 2010, In : Leukemia. 24, 7, p. 1388-1392 5 p.

Research output: Contribution to journalLetterAcademicpeer-review

2007

Depletion of CD4+/CD25high regulatory T cells may enhance or uncover factor VIII-specific T-cell responses in healthy individuals [1]

Kamaté, C., Lenting, P. J., Van Den Berg, H. M. & Mutis, T., 1 Mar 2007, In : Journal of Thrombosis and Haemostasis. 5, 3, p. 611-613 3 p.

Research output: Contribution to journalLetterAcademicpeer-review

2006

Flt-3 internal tandem duplication hampers differentiation of AML blasts towards leukemic dendritic cells

Houtenbos, I., Westers, T. M., Ossenkoppele, G. J., van de Loosdrecht, A. A., Hess, C. J. & Waisfisz, Q., Oct 2006, In : Leukemia. 20, 10, p. 1892-1895

Research output: Contribution to journalLetterAcademicpeer-review

2004

Secondary imatinib resistance associated with an aberrant bcr-abl fusion gene

Janssen, JJWM., Hochhaus, A., van Oostveen, JW., Waisfisz, Q., Schuurhuis, GJ. & Ossenkoppele, GJ., May 2004, In : Leukemia. 18, 5, p. 1020-1021

Research output: Contribution to journalLetterAcademicpeer-review

Susceptibility of malignant plasma cells to HA-1H specific lysis suggests a role for the minor histocompatibility antigen HA-1 in the graft-versus-myeloma effect [3]

Holloway, P. A., Kaldenhoven, N., van Dijk, M., Bloem, A. C., de Lau, W., van der Zee, R., Kircher-Eibl, B., Mutis, T. & Lokhorst, H. M., 1 Jan 2004, In : Leukemia. 18, 9, p. 1543-1545 3 p.

Research output: Contribution to journalLetterAcademicpeer-review

1999

Induction of minor histocompatibility antigen HA-1-specific cytotoxic T cells for the treatment of leukemia after allogeneic stem cell transplantation (multiple letters)

Brossart, P., Spahlinger, B., Grunebach, F., Stuhler, G., Reichardt, V. L., Kanz, L., Brugger, W., Mutis, T. & Goulmy, E., 1 Jan 1999, In : Blood. 94, 12, p. 4374-4376 3 p.

Research output: Contribution to journalLetterAcademicpeer-review