Medical oncology laboratory

Research Output 1989 2019

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2019

2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors

Cascioferro, S., Parrino, B., Petri, G. L., Cusimano, M. G., Schillaci, D., di Sarno, V., Musella, S., Giovannetti, E., Cirrincione, G. & Diana, P., 2019, In : European Journal of Medicinal Chemistry. 167, p. 200-210

Research output: Contribution to journalArticleAcademicpeer-review

Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expression

Berndsen, R. H., Castrogiovanni, C. D., Weiss, A., Rausch, M., Dallinga, M. G., Miljkovic-Licina, M., Klaassen, I., Meraldi, P., van Beijnum, J. R. & Nowak-Sliwinska, P., 2019, In : British Journal of Cancer.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

CD31-positive microvessel density within adenomas of Lynch Syndrome patients is similar compared to adenomas of non-Lynch patients

Vleugels, J. L. A., van Neerven, S. M., van Leerdam, M. E., Wanders, L. K., de Wit, M., Carvalho, B., Delis-van Diemen, P. M., Kallenberg, F. G. J., Vermeulen, L., Beliën, J. A., East, J. E., Meijer, G. A. & Dekker, E., May 2019, In : Endoscopy International Open. 7, 5, p. E701-E707

Research output: Contribution to journalArticleAcademicpeer-review

Changes in the urinary extracellular vesicle proteome are associated with nephronophthisis-related ciliopathies

Stokman, M. F., Bijnsdorp, I. V., Schelfhorst, T., Pham, T. V., Piersma, S. R., Knol, J. C., Giles, R. H., Bongers, E. M. H. F., Knoers, N. V. A. M., Lilien, M. R., Jiménez, C. R. & Renkema, K. Y., 10 Feb 2019, In : Journal of Proteomics. 192, p. 27-36 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies

Moors, T. E., Paciotti, S., Ingrassia, A., Quadri, M., Breedveld, G., Tasegian, A., Chiasserini, D., Eusebi, P., Duran-Pacheco, G., Kremer, T., Calabresi, P., Bonifati, V., Parnetti, L., Beccari, T. & van de Berg, W. D. J., 1 Feb 2019, In : Molecular Neurobiology. 56, 2, p. 1344-1355 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Coexisting Molecular Determinants of Acquired Oxaliplatin Resistance in Human Colorectal and Ovarian Cancer Cell Lines

Noordhuis, P., Laan, A. C., van de Born, K., Honeywell, R. J. & Peters, G. J., 2019, In : International Journal of Molecular Sciences. 20, 15

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line

van der Steen, N., Leonetti, A., Keller, K., Dekker, H., Funel, N., Lardon, F., Ruijtenbeek, R., Tiseo, M., Rolfo, C., Pauwels, P., Peters, G. J. & Giovannetti, E., 2019, In : Biochemical Pharmacology. 166, p. 128-138

Research output: Contribution to journalArticleAcademicpeer-review

DNA methyltransferases expression in normal tissues and various human cancer cell lines, xenografts and tumors.

Honeywell, R. J., Sarkisjan, D., Kristensen, M. H., de Klerk, D. J. & Peters, G. J., 19 Jan 2019, In : Nucleosides, Nucleotides and Nucleic Acids. p. 1-13

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Folate receptors and transporters: Biological role and diagnostic/therapeutic targets in cancer and other diseases

Frigerio, B., Bizzoni, C., Jansen, G., Leamon, C. P., Peters, G. J., Low, P. S., Matherly, L. H. & Figini, M., 2019, In : JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 38, 1, 125.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

From ‘targeted therapy’ to targeted therapy*

Peters, G. J., 2019, In : Anticancer Research. 39, 7, p. 3341-3345

Research output: Contribution to journalArticleAcademicpeer-review

High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome

Blijlevens, M., van der Meulen-Muileman, I. H., de Menezes, R. X., Smit, E. F. & van Beusechem, V. W., 31 Jan 2019, In : Oncogene.

Research output: Contribution to journalArticleAcademicpeer-review

Human testis phosphoproteome reveals kinases as potential targets in spermatogenesis and testicular cancer

Castillo, J., Knol, J. C., Korver, C. M., Piersma, S. R., Pham, T. V., de Goeij-de Haas, R. R., van Pelt, A. M. M., Jimenez, C. R. & Jansen, B. J. H., 2019, In : Molecular and Cellular Proteomics. 18, p. S132-S144

Research output: Contribution to journalArticleAcademicpeer-review

Hybrid ligands with calixarene and thiodigalactoside groups: Galectin binding and cytotoxicity

Zhang, H., Ippel, H., Miller, M. C., Wong, T. J., Griffioen, A. W., Mayo, K. H. & Pieters, R. J., 2019, In : Organic Chemistry Frontiers. 6, 16, p. 2981-2990

Research output: Contribution to journalArticleAcademicpeer-review

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

Beekhof, R., van Alphen, C., Henneman, A. A., Knol, J. C., Pham, T. V., Rolfs, F., Labots, M., Henneberry, E., le Large, T. Y., de Haas, R. R., Piersma, S. R., Vurchio, V., Bertotti, A., Trusolino, L., Verheul, H. M. & Jimenez, C. R., 2019, In : Molecular Systems Biology. 15, 4, p. e8250

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Novel targeted strategies to overcome resistance in small-cell lung cancer: focus on PARP inhibitors and rovalpituzumab tesirine

van den Borg, R., Leonetti, A., Tiseo, M., Giovannetti, E. & Peters, G. J., 2019, In : Expert Review of Anticancer Therapy. 19, 6, p. 461-471

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Oncofoetal insulin receptor isoform A marks the tumour endothelium; an underestimated pathway during tumour angiogenesis and angiostatic treatment

Nowak-Sliwinska, P., van Beijnum, J. R., Huijbers, E. J. M., Gasull, P. C., Mans, L., Bex, A. & Griffioen, A. W., 22 Jan 2019, In : British Journal of Cancer. 120, 2, p. 218-228 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacogenetics of treatments for pancreatic cancer

el Hassouni, B., Li Petri, G., Liu, D. S. K., Cascioferro, S., Parrino, B., Hassan, W., Diana, P., Ali, A., Frampton, A. E. & Giovannetti, E., 2019, In : Expert Opinion on Drug Metabolism and Toxicology. 15, 6, p. 437-447

Research output: Contribution to journalArticleAcademicpeer-review

Platelets: the holy grail in cancer blood biomarker research?

Sabrkhany, S., Kuijpers, M. J. E., Griffioen, A. W. & Oude Egbrink, M. G. A., 15 Feb 2019, In : Angiogenesis. 22, 1

Research output: Contribution to journalArticleAcademicpeer-review

Predictive Performance of Cardiovascular Disease Risk Prediction Algorithms in People Living With HIV

van Zoest, R. A., Law, M., Sabin, C. A., Vaartjes, I., Van der Valk, M., Arends, J. E., Reiss, P., Wit, F. W. M. N., Geerlings, S. E., Godfried, M. H., Goorhuis, A., Hovius, J. W., Kuijpers, T. W., Nellen, F. J. B., van der Poll, D. T., Prins, J. M., van Vugt, H. J. M., Wiersinga, W. J., Wit, F. W. M. N., van Duinen, M. & 267 othersvan Eden, J., van Hes, A. M. H., Pijnappel, F. J. J., Weijsenfeld, A. M., Jurriaans, S., Back, N. K. T., Zaaijer, H. L., Berkhout, B., Cornelissen, M. T. E., Schinkel, C. J., Wolthers, K. C., Peters, E. J. G., van Agtmael, M. A., Bomers, M., Heitmuller, M., Laan, L. M., Ang, C. W., van Houdt, R., Pettersson, A. M., Vandenbroucke-Grauls, C. M. J. E., van den Berge, M., Stegeman, A., Baas, S., de Looff, L. H., Wintermans, B., Veenemans, J., Pronk, M. J. H., Ammerlaan, H. S. M., de Munnik, E. S., Jansz, A. R., Tjhie, J., Wegdam, M. C. A., Deiman, B., Scharnhorst, V., van Eeden, A., Brokking, W., Groot, M., Elsenburg, L. J. M., Damen, M., Kwa, I. S., van Kasteren, M. E. E., Brouwer, A. E., van Erve, R., de Kruijf-van de Wiel, B. A. F. M., van de Ven, B., Buiting, A. G. M., Kabel, P. J., Versteeg, D., van der Ende, M. E., Bax, H. I., van Gorp, E. C. M., Nouwen, J. L., Rijnders, B. J. A., Schurink, C. A. M., Verbon, A., de Vries-Sluijs, T. E. M. S., de Jong-Peltenburg, N. C., Bassant, N., van Beek, J. E. A., Vriesde, M., van Zonneveld, L. M., van den Berg-Cameron, H. J., de Groot, J., de Zeeuw-de Man, M., Boucher, C. A. B., Koopmans, M. P. G., van Kampen, J. J. A., Pas, S. D., Branger, J., Douma, R. A., Duijf-van de Ven, C. J. H. M., Schippers, E. F., van Nieuwkoop, C., van IJperen, J. M., Geilings, J., van der Hut, G., van Burgel, N. D., Leyten, E. M. S., Gelinck, L. B. S., Davids-Veldhuis, S., van Hartingsveld, A. Y., Meerkerk, C., Wildenbeest, G. S., Heikens, E., Groeneveld, P. H. P., Bouwhuis, J. W., Lammers, A. J. J., Kraan, S., van Hulzen, A. G. W., Kruiper, M. S. M., van der Bliek, G. L., Bor, P. C. J., Bloembergen, P., Wolfhagen, M. J. H. M., Ruijs, G. J. H. M., Kroon, F. P., de Boer, M. G. J., Scheper, H., Jolink, H., Dorama, W., van Holten, N., Claas, E. C. J., Wessels, E., den Hollander, J. G., Pogany, K., Roukens, A., Kastelijns, M., Smit, J. V., Smit, E., Struik-Kalkman, D., Tearno, C., van Niekerk, T., Pontesilli, O., Lowe, S. H., Lashof, A. M. L. O., Posthouwer, D., Ackens, R. P., Burgers, K., Schippers, J., Weijenberg-Maes, B., van Loo, I. H. M., Havenith, T. R. A., Mulder, J. W., Vrouenraets, S. M. E., Lauw, F. N., van Broekhuizen, M. C., Vlasblom, D. J., Smits, P. H. M., Weijer, S., El Moussaoui, R., Bosma, A. S., van Vonderen, M. G. A., Kampschreur, L. M., Dijkstra, K., Faber, S., Weel, J., Kootstra, G. J., Delsing, C. E., van der Burg-van de Plas, M., Heins, H., Kortmann, W., van Twillert, G., Renckens, R., Ruiter-Pronk, D., van Truijen-Oud, F. A., Stuart, J. W. T. C., IJzerman, E. P., Jansen, R., Rozemeijer, van der Reijden, W. A., Brinkman, K., van den Berk, G. E. L., Blok, W. L., Frissen, P. H. J., Lettinga, K. D., Schouten, W. E. M., Veenstra, J., Brouwer, A. E., Geerders, G. F., Hoeksema, K., Kleene, M. J., van der Meche, I. B., Spelbrink, M., Toonen, A. J. M., Wijnands, S., Kwa, D., Regez, R., van Crevel, R., Keuter, M., van der Ven, A. J. A. M., ter Hofstede, H. J. M., Dofferhoff, A. S. M., Hoogerwerf, J., Grintjes-Huisman, K. J. T., de Haan, M., Marneef, M., Rahamat-Langendoen, J., Stelma, F. F., Burger, D., Gisolf, E. H., Hassing, R. J., Claassen, M., ter Beest, G., van Bentum, P. H. M., Langebeek, N., Tiemessen, R., Swanink, C. M. A., van Lelyveld, S. F. L., Soetekouw, R., van der Prijt, L. M. M., van der Swaluw, J., Bermon, N., van der Reijden, W. A., Jansen, R., Herpers, B. L., Veenendaal, D., Verhagen, D. W. M., van Wijk, M., Bierman, W. F. W., Bakker, M., Kleinnijenhuis, J., Kloeze, E., Stienstra, Y., Wilting, K. R., Wouthuyzen-Bakker, M., Boonstra, A., van der Meulen, P. A., de Weerd, D. A., Niesters, H. G. M., van Leer-Buter, C. C., Knoester, M., Hoepelman, A. I. M., Barth, R. E., Bruns, A. H. W., Ellerbroek, P. M., Mudrikova, T., Oosterheert, J. J., Schadd, E. M., Wassenberg, M. W. M., van Zoelen, M. A. D., Aarsman, K., van Elst-Laurijssen, D. H. M., de Kroon, I., van Rooijen, C. S. A. M., van Berkel, M., van Rooijen, C. S. A. M., Schuurman, R., VerduynLunel, F., Wensing, A. M. J., Zaheri, S., Bezemer, D. O., van Sighem, A. I., Smit, C., Hillebregt, M., de Jong, A., Woudstra, T., Bergsma, D., Grivell, S., Meijering, R., Raethke, M., Rutkens, T., de Groot, L., van den Akker, M., Bakker, Y., Bezemer, M., El Berkaoui, A., Geerlinks, J., Koops, J., Kruijne, E., Lodewijk, C., Lucas, E., van der Meer, R., Munjishvili, L., Paling, F., Peeck, B., Ree, C., Regtop, R., Ruijs, Y., van de Sande, L., Schoorl, M., Schnorr, P., Tuijn, E., Veenenberg, L., van der Vliet, S., Wisse, A., Witte, E. C. & Tuk, B., 15 Aug 2019, In : Journal of Acquired Immune Deficiency Syndromes. 81, 5, p. 562-571

Research output: Contribution to journalArticleAcademicpeer-review

Progression of liver fibrosis following acute hepatitis C virus infection in HIV-positive MSM

Newsum, A. M., Kooij, K. W., Boyd, A., Smit, C., Wit, F. W. N. M., van der Meer, J. T. M., Prins, M., Reiss, P., van der Valk, M., van Eden, H., Molenkamp, R., Pijnappel, F. J. J., Reesink, H. W., Schinkel, J., Steba, G. S., van den Berk, G. E. L., Brinkman, K., Hooijenga, I., Kwa, D., van der Meche, N. & 301 othersToonen, A. J. M., Vos, D., van Broekhuizen, M. C., Lauw, E. N., Mulder, J. W., Arend, J. E., van Kessel, A., Silvius, B., Versloot, M., Boonstra, A., Rijnders, B. J. A., Brokking, W., van Eeden, A., Elsenburg, L., Nobel, H. E., van de Laar, T. J. W., van der Veldt, W., Geerlings, S. E., Goorhuis, A., Hovius, J. W., Lempkes, B., Nellen, F. J. B., van der Poll, T., Prins, J. M., van Vugt, M., Wiersinga, W. J., van Duinen, M., van Eden, J., Hazenberg, A., van Hes, A. M. H., Pijnappel, F. J. J., Smalhout, S. Y., Weijsenfeld, A. M., Jurriaans, S., Back, N. K. T., Zaaijer, H. L., Berkhout, B., Cornelissen, M. T. E., Schinkel, C. J., Wolthers, K. C., Peters, E. J. G., van Agtmael, M. A., Bomers, M., Sigaloff, K. C. E., Heitmuller, M., Laan, L. M., Ang, C. W., van Houdt, R., Jonges, M., Pettersson, A. M., van Prehn, J., van den Berge, M., Stegeman, A., Baas, S., de Looff, L. H., Wintermans, B., Veenemans, J., Pronk, M. J. H., Ammerloan, H. S. M., de Munnik, E. S., Jansz, A. R., Tjhie, J., Wegdam, M. C. A., Deiman, B., Scharnhorst, V., Elsenburg, L. J. M., Nobel, H., Damen, M., van Kasteren, M. E. E., Berrevoets, M. A. H., Brouwer, A. E., Adams, A., de Kruijf-van de Wiel, B. A. E., Keelan-Pfaf, S., van der Ven, B., van der Ven, B., Buiting, A. G. M., Murck, J. L., Versteeg, D., van der Ende, M. E., Box, H. . I., van Gorp, E. C. M., Nouwen, J. L., Schurink, C. A. M., Verbon, A., de Vries-Sluijs, T. E. M. S., de Jong-Peltenburg, N. C., Bassant, N., van Beek, J. E. A., Vriesde, M., van Zonneveld, L. M., van den Berg-Cameron, H. J., de Groot, J., Boucher, C. A. B., Koopmans, M. P. G., van Kampen, J. J. A., Branger, J., Douma, R. A., Duijf-van de Ven, C. J. H. M., Schippers, E. F., van Nieuwkoop, C., van IJperen, J. M., Geilings, J., van der Hut, G., van Burgel, N. D., Leyten, E. M. S., Gelinck, L. B. S., Mollema, F., Davids-Veldhuis, S., van Hartingsveld, A. Y., Wildenbeest, G. S., Heikens, E., Groeneveld, P. H. P., Bouwhuis, J. W., Lammers, A. J. J., Kraan, S., van Hulzen, A. G. W., Kruiper, M. S. M., van der Bliek, G. L., Bor, P. C. J., Bloembergen, P., Wolthagen, M. H. M., Ruijs, G. J. H. M., Kroon, E., de Boer, M. G. J., Scheper, H., Jolink, H., Dorama, W., van Holten, N., Claas, E. C. J., Wessels, E., den Hollander, J. G., Pogany, K., Roukens, A., Douma, R., Kastelijns, M., Smit, J. . V., Smit, E., Struik-Kalkman, D., Tearno, C., van Niekerk, T., Pontesilli, O., Lowe, S. H., Lashof, A. M. L. O., Posthouwer, D., Ackens, R. P., Burgers, K., Schippers, J., Enberg-Maes, B. W., van Loo, I. H. M., Havenith, T. R. A., Vrouenraets, S. M. E., van Broekhuizen, M. C., Vlasblom, D. J., Kroeze, M., Smits, P. H. M., Weijer, S., El Moussaoui, R., Bosma, A. S., van Vonderen, M. G. A., Kampschreur, L. M., Faber, S., Steeman-Bouma, R., Wed, J., Kootstra, G. J., Delsing, C. E., van der Burg-van de Plas, M., Heins, H., Kortmann, W., van Twillert, G., Renckens, R., Ruiter-Pronk, D., van Truijen-Oud, E. A., Stuart, J. W. T. C., Jansen, E. R., Hoogewerf, M., Rozemeijer, W., van der Reijden, W. A., Sinnige, J. C., Blok, W. L., Frissen, P. H. J., Lettinga, K. D., Schouten, W. E. M., Veenstra, J., Brouwer, A. E., Geerders, G. E., Hoeksema, K., Kleene, M. J., Knapen, M., van der Meche, I. B., Mulder-Seeleman, E., Toonen, A. J. M., Wijnands, S., van Crevel, R., Dofferhoff, A. S. M., ter Hofstede, H. J. M., Hoogerwerf, J., Keuter, M., Richel, O., Albers, M., Grintjes-Huisman, K. J. T., de Haan, M., Marneef, M., Strik-Albers, R., Rahamat-Langendoen, J., Stelma, E. E., Burger, D., Gisolf, E. H., Hassing, R. J., Claassen, M., ter Beest, G., van Bentum, P. H. M., Langebeek, N., Tiemessen, R., Swanink, C. M. A., van Lelyveld, S. F. L., Soetekouw, R., van der Prijt, L. M. M., van der Swaluw, J., Bermon, N., Jansen, R., Herpers, B. L., Veenendaal, D., Verhagen, D. W. M., van Wijk, M., Bierman, W. F. W., Bakker, M., Kleinnijenhuis, J., Kloeze, E., Middel, A., Stienstra, Y., Vermont, C. L., Wouthuyzen-Bakker, K. M., Jonge, H. D. G., van der Meulen, P. A., de Weerd, D. A., Niesters, H. G. M., van Leer-Buter, C. C., Knoester, M., Hoepelman, A. I. M., Arends, J., Barth, R. E., Bruns, A. H. W., Ellerbroek, P. M., Mudrikova, T., Oosterheert, J. J., de Regt, M. J. A., Schadd, E. M., Wassenberg, M. W. M., van Zoelen, M. A. D., Aarsman, K., Griffioen-van Santen, B. M. G., de Kroon, I., van Rooijen, C. S. A. M., van Berkel, M., Schuurman, R., Verduyn-Lunel, E., Wensing, A. M. J., Zaheri, S., Bezemer, D. O., van Sighem, A. . I., Hillebregt, M., de Jong, A., Woudstra, T., Bergsma, D., Grivell, S., Meijering, R., Raethke, M., Rutkens, T., de Groot, L., van den Akker, M., Bakker, Y., El Berkaoui, A., Bezemer, M., Bretin, N., Djoechro, E., Geerlinks, J., Kruijne, E., Lodewijk, C., Lucas, E., van der Meer, R., Munjishvili, L., Paling, E., Peeck, B., Ree, C., Regtop, R., Ruijs, Y., van de Sande, L., Schoorl, M., Schnorr, P., Tuijn, E., Veenenberg, L., van der Vliet, S., Witte, E. C., Tuk, B., Arends, J., Rijnders, B., Schutten, M., de Vries-Sluys, T. E. M. S., Richter, C. & Vollaard, A., 1 Apr 2019, In : AIDS. 33, 5, p. 833-844

Research output: Contribution to journalArticleAcademicpeer-review

Role of c-MET inhibitors in overcoming drug resistance in spheroid models of primary human pancreatic cancer and stellate cells

Firuzi, O., Che, P. P., el Hassouni, B., Buijs, M., Coppola, S., Löhr, M., Funel, N., Heuchel, R., Carnevale, I., Schmidt, T., Mantini, G., Avan, A., Saso, L., Peters, G. J. & Giovannetti, E., 2019, In : Cancers. 11, 5, 638.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment

Balboni, B., el Hassouni, B., Honeywell, R. J., Sarkisjan, D., Giovannetti, E., Poore, J., Heaton, C., Peterson, C., Benaim, E., Lee, Y. B., Kim, D. J. & Peters, G. J., 2019, In : Expert Opinion on Investigational Drugs. 28, 4, p. 311-322

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

van Pul, K. M., Vuylsteke, R. J. C. L. M., van de Ven, R., Te Velde, E. A., Rutgers, E. J. T., van den Tol, P. M., Stockmann, H. B. A. C. & de Gruijl, T. D., 22 May 2019, In : Journal for Immunotherapy of Cancer. 7, 1, p. 133

Research output: Contribution to journalArticleAcademicpeer-review

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

Sciarrillo, R., Wojtuszkiewicz, A., El Hassouni, B., Funel, N., Gandellini, P., Lagerweij, T., Buonamici, S., Blijlevens, M., Zeeuw van der Laan, E. A., Zaffaroni, N., Deraco, M., Kusamura, S., Würdinger, T., Peters, G. J., Molthoff, C. F. M., Jansen, G., Kaspers, G. J. L., Cloos, J. & Giovannetti, E., Jan 2019, In : EBioMedicine. 39, p. 215-225

Research output: Contribution to journalArticleAcademicpeer-review

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

Dirkse, A., Golebiewska, A., Buder, T., Nazarov, P. V., Muller, A., Poovathingal, S., Brons, N. H. C., Leite, S., Sauvageot, N., Sarkisjan, D., Seyfrid, M., Fritah, S., Stieber, D., Michelucci, A., Hertel, F., Herold-Mende, C., Azuaje, F., Skupin, A., Bjerkvig, R., Deutsch, A. & 2 othersVoss-Böhme, A. & Niclou, S. P., 2019, In : Nature Communications. 10, 1, 1787.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Stereotactic ablative radiotherapy for the comprehensive treatment of 4-10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial

Palma, D. A., Olson, R., Harrow, S., Correa, R. J. M., Schneiders, F., Haasbeek, C. J. A., Rodrigues, G. B., Lock, M., Yaremko, B. P., Bauman, G. S., Ahmad, B., Schellenberg, D., Liu, M., Gaede, S., Laba, J., Mulroy, L., Senthi, S., Louie, A. V., Swaminath, A., Chalmers, A. & 5 othersWarner, A., Slotman, B. J., de Gruijl, T. D., Allan, A. & Senan, S., 2019, In : BMC Cancer. 19, 1, 816.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Uridine cytidine kinase 2 as a potential biomarker for treatment with RX-3117 in pancreatic cancer*

Hassouni, B. E. L., Infante, J., Mantini, G., Ricci, C., Funel, N., Giovannetti, E. & Peters, G. J., 2019, In : Anticancer Research. 39, 7, p. 3609-3614

Research output: Contribution to journalArticleAcademicpeer-review

Urinary exosomal proteins as (pan-)cancer biomarkers: insights from the proteome

Erozenci, L. A., Böttger, F., Bijnsdorp, I. V. & Jimenez, C. R., 2019, In : FEBS Letters. 593, 13, p. 1580-1597

Research output: Contribution to journalArticleAcademicpeer-review

2018

5'-nucleotidase cN-II emerges as a new predictive biomarker of response to gemcitabine/platinum combination chemotherapy in non-small cell lung cancer

Toffalorio, F., Santarpia, M., Radice, D., Jaramillo, C. A., Spitaleri, G., Manzotti, M., Catania, C., Jordheim, L. P., Pelosi, G., Peters, G. J., Tibaldi, C., Funel, N., Spaggiari, L., de Braud, F., de Pas, T. & Giovannetti, E., 2018, In : Oncotarget. 9, 23, p. 16437-16450 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy

Chakraborty, A., Kamermans, A., van Het Hof, B., Castricum, K., Aanhane, E., van Horssen, J., Thijssen, V. L., Scheltens, P., Teunissen, C. E., Fontijn, R. D., van der Flier, W. M. & de Vries, H. E., 2018, In : Brain : a journal of neurology. 141, 12, p. 3377-3388 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

An improved conjugate vaccine technology; induction of antibody responses to the tumor vasculature

Huijbers, E. J. M., van Beijnum, J. R., Lê, C. T., Langman, S., Nowak-Sliwinska, P., Mayo, K. H. & Griffioen, A. W., 2018, In : Vaccine. 36, 21, p. 3054-3060

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A novel allogeneic off-the-shelf dendritic cell vaccine for post-remission treatment of elderly patients with acute myeloid leukemia

van de Loosdrecht, A. A., van Wetering, S., Santegoets, S. J. A. M., Singh, S. K., Eeltink, C. M., den Hartog, Y., Koppes, M., Kaspers, J., Ossenkoppele, G. J., Kruisbeek, A. M. & de Gruijl, T. D., 1 Oct 2018, In : Cancer Immunology and Immunotherapy. 67, 10, p. 1505-1518 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A safety and immunogenicity study of immunization with hVEGF/RFASE in cynomolgus monkeys

Wentink, M. Q., Verheul, H. M. W., Griffioen, A. W., Schafer, K. A., McPherson, S., Early, R. J., van der Vliet, H. J. & de Gruijl, T. D., 5 Apr 2018, In : Vaccine. 36, 15, p. 2025-2032 8 p.

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Open Access

A tribute to Francoise Poirier (1954-2018)

Collignon, J., Dang, T., Delacour, D., Jacob, R., Leffler, H., Ludger, J., Rabinovich, G. A., Rousset, J. P., Thijssen, V. L. & Viguier, M., Jun 2018, In : Glycobiology. 28, 6, p. 348-348

Research output: Contribution to journalArticleAcademic

Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer

Jacobsen, A., Bosch, L. J. W., Martens-de Kemp, S. R., Carvalho, B., Sillars-Hardebol, A. H., Dobson, R. J., de Rinaldis, E., Meijer, G. A., Abeln, S., Heringa, J., Fijneman, R. J. A. & Feenstra, K. A., 2018, In : Scientific Reports. 8, 1, 7522.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer

van de Ven, R., Hilton, T. L., Hu, H-M., Dubay, C. J., Haley, D., Paustian, C., Puri, S., Urba, W. J., Curti, B. D., Aung, S. & Fox, B. A., 2 Dec 2018, In : OncoImmunology. 7, 12, e1466766.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

Steenbeek, S. C., Pham, T. V., de Ligt, J., Zomer, A., Knol, J. C., Piersma, S. R., Schelfhorst, T., Huisjes, R., Schiffelers, R. M., Cuppen, E., Jimenez, C. R. & van Rheenen, J., 2018, In : EMBO Journal. 37, 15, e98357.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cancer immunophenotyping by 7 colour multispectral imaging without tyramide signal amplification

Ijselstein, M., Brouwer, T., Abdulrahman, Z., Reidy, E., Ramalheiro, A., Heeren, AM., Vahrmeijer, A., Jordanova, ES. & de Miranda, N., 7 Sep 2018, In : The Journal of Pathology: Clinical Research.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

CD40L coding oncolytic adenovirus allows long-term survival of humanized mice receiving dendritic cell therapy

Zafar, S., Sorsa, S., Siurala, M., Hemminki, O., Havunen, R., Cervera-Carrascon, V., Santos, J. M., Wang, H., Lieber, A., de Gruijl, T., Kanerva, A. & Hemminki, A., 2018, In : OncoImmunology. 7, 10, e1490856.

Research output: Contribution to journalArticleAcademicpeer-review

Consensus molecular subtype classification of colorectal adenomas

In collaboration with the NGS-ProToCol Consortium:, Komor, M. A., Bosch, L. J. W., Bounova, G., Bolijn, A. S., Delis-van Diemen, P. M., Rausch, C., Hoogstrate, Y., Stubbs, A. P., de Jong, M., Jenster, G., van Grieken, N. C. T., Carvalho, B., Wessels, L. F. A., Jimenez, C. R., Fijneman, R. J. A. & Meijer, G. A., 2018, In : Journal of Pathology. 246, 3, p. 266-276

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Open Access

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

Büning, H., Griesenbach, U., Fehse, B., Ylä-Herttuala, S., Anagnou, N. P., van Beusechem, V., Raya, A. & Verhoeyen, E., 1 Dec 2018, In : Human Gene Therapy. 29, 12, p. 1337-1338 2 p., 081.

Research output: Contribution to journalArticleAcademic

Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer: a prospective validation study

Italian Oncological Group of Clinical Research (GOIRC), Tibaldi, C., Camerini, A., Tiseo, M., Mazzoni, F., Barbieri, F., Vittimberga, I., Brighenti, M., Boni, L., Baldini, E., Gilli, A., Honeywell, R., Chartoire, M., Peters, G. J. & Giovannetti, E., 27 Nov 2018, In : British Journal of Cancer. 119, 11, p. 1326-1331 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Different angioregulatory activity of monovalent galectin-9 isoforms

Aanhane, E., Schulkens, I. A., Heusschen, R., Castricum, K., Leffler, H., Griffioen, A. W. & Thijssen, V. L., 1 Aug 2018, In : Angiogenesis. 21, 3, p. 545-555 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Double Trouble: A Case Series on Concomitant Genetic Aberrations in NSCLC

Van Der Steen, N., Mentens, Y., Ramael, M., Leon, L. G., Germonpré, P., Ferri, J., Gandara, D. R., Giovannetti, E., Peters, G. J., Pauwels, P. & Rolfo, C., Jan 2018, In : Clinical Lung Cancer. 19, 1, p. 35-41

Research output: Contribution to journalArticleAcademicpeer-review