Research Output

Article

An effective modestly intensive re-induction regimen with bortezomib in relapsed or refractory paediatric acute lymphoblastic leukaemia

Kaspers, G. J. L., Niewerth, D., Wilhelm, B. A. J., Scholte-van Houtem, P., Lopez-Yurda, M., Berkhof, J., Cloos, J., de Haas, V., Mathôt, R. A., Attarbaschi, A., Baruchel, A., de Bont, E. S., Fagioli, F., Rössig, C., Klingebiel, T., De Moerloose, B., Nelken, B., Palumbo, G., Reinhardt, D., Rohrlich, P. S. & 3 others, Simon, P., von Stackelberg, A. & Zwaan, C. M., 1 May 2018, In : British Journal of Haematology. 181, 4, p. 523-527 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

An efficient method for the transduction of primary pediatric glioma neurospheres

Meel, M. H., Metselaar, D. S., Waranecki, P., Kaspers, G. J. L. & Hulleman, E., 2018, In : MethodsX. 5, p. 173-183

Research output: Contribution to journalArticleAcademicpeer-review

A new era for children with diffuse intrinsic pontine glioma: hope for cure?

Jansen, M. H. A. & Kaspers, G. J. L., 2012, In : Expert Review of Anticancer Therapy. 12, 9, p. 1109-1112

Research output: Contribution to journalArticleAcademicpeer-review

A new leukodystrophy with brainstem and spinal cord involvement and high lactate

Van der Knaap, M. S., Van Der Voorn, P., Barkhof, F., Van Coster, R., Krägeloh-Mann, I., Feigenbaum, A., Blaser, S., Vles, J. S. H., Rieckmann, P. & Pouwels, P. J. W., 1 Feb 2003, In : Annals of Neurology. 53, 2, p. 252-258 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A new link between steroid resistance, glucocorticoid receptor and nuclear factor kappa B p65 in idiopathic nephrotic syndrome

Szilagyi, K., Podracka, L., Franke, N. E., Mojzis, J. & Mirossay, L., 2009, In : Neuroendocrinology Letters. 30, 5, p. 629-636

Research output: Contribution to journalArticleAcademicpeer-review

A new murine model to study the pathogenesis of tuberculous meningitis

Van Well, G. T. J., Wieland, C. W., Florquin, S., Roord, J. J., Van Der Poll, T. & Van Furth, A. M., 1 Mar 2007, In : Journal of Infectious Diseases. 195, 5, p. 694-697 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

An examination of the biodevelopment of gender expression in children ages 6- to 12-years

Coome, L. A., Skorska, M. N., van der Miesen, A. I. R., Peragine, D. E. & van der Laan, D. P., 2018, In : Canadian Journal of Human Sexuality. 27, 2, p. 133-143

Research output: Contribution to journalArticleAcademicpeer-review

An expert panel-based study on recognition of gastro-esophageal reflux in difficult esophageal pH-impedance tracings

Smits, M. J., Loots, C. M., van Wijk, M. P., Bredenoord, A. J., Benninga, M. A. & Smout, A. J. P. M., May 2015, In : Neurogastroenterology and Motility. 27, 5, p. 637-45 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Angstsymptomen als uiting van onthouding van midazolam op de kinderintensivecare; soms moeilijk te voorkomen en te herkennen, maar eenvoudig te behandelen

Translated title of the contribution: Anxiety symptoms as an expression of withdrawal of midazolam at the pediatric intensive care unit: Sometimes difficult to prevent and to recognize, but easy to treatGoudswaard, J., De Vries, A. L. C. & Plötz, F. B., 1 Feb 2006, In : Tijdschrift voor Kindergeneeskunde. 74, 1, p. 18-21 4 p.

Research output: Contribution to journalArticleProfessional

An IGF-I promoter polymorphism modifies the relationships between birth weight and risk factors for cardiovascular disease and diabetes at age 36

te Velde, S. J., van Rossum, E. F. C., Voorhoeve, P. G., Twisk, J. W. R., Delemarre van de Waal, H. A., Stehouwer, C. D. A., van Mechelen, W., Lamberts, S. W. J. & Kemper, H. C. G., 1 Jun 2005, In : BMC Endocrine Disorders. 5, p. 5

Research output: Contribution to journalArticleAcademicpeer-review

Animal models of tuberculosis: Zebrafish

van Leeuwen, L. M., van der Sar, A. M. & Bitter, W., 2015, In : Cold Spring Harbor perspectives in medicine. 5, 3, a018580.

Research output: Contribution to journalArticleAcademicpeer-review

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P-C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S-J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M-F., Rotter, J. I., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D. I., Bell, J. T., Demirkan, A. & van Duijn, C. M., 1 Dec 2019, In : Nature Communications. 10, 1, p. 2581 2581.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

An international registry for primary ciliary dyskinesia

Werner, C., Lablans, M., Ataian, M., Raidt, J., Wallmeier, J., Grosse-Onnebrink, J., Kuehni, C. E., Haarman, E. G., Leigh, M. W., Quittner, A. L., Lucas, J. S., Hogg, C., Witt, M., Priftis, K. N., Yiallouros, P., Nielsen, K. G., Santamaria, F., Uckert, F. & Omran, H., Mar 2016, In : European Respiratory Journal. 47, 3, p. 849-859

Research output: Contribution to journalArticleAcademicpeer-review

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3

Hoff, S., Halbritter, J., Epting, D., Frank, V., Nguyen, T. M. T., van Reeuwijk, J., Boehlke, C., Schell, C., Yasunaga, T., Helmstadter, M., Mergen, M., Filhol, E., Boldt, K., Horn, N., Ueffing, M., Otto, E. A., Eisenberger, T., Elting, M. W., van Wijk, J. A. E., Bockenhauer, D. & 21 others, Sebire, N. J., Rittig, S., Vyberg, M., Ring, T., Pohl, M., Pape, L., Neuhaus, T. J., Elshakhs, N. A. S., Koon, S. J., Harris, P. C., Grahammer, F., Huber, T. B., Kuehn, E. W., Kramer-Zucker, A., Bolz, H. J., Roepman, R., Saunier, S., Walz, G., Hildebrandt, F., Bergmann, C. & Lienkamp, S. S., 2013, In : Nature Genetics. 45, 8, p. 951-956

Research output: Contribution to journalArticleAcademicpeer-review

A non-enzymatic function of 17 beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

Rauschenberger, K., Scholer, K., Sass, J. O., Sauer, S., Djuric, Z., Rumig, C., Wolf, N. I., Okun, J. G., Kolker, S., Schwarz, H., Fischer, C., Grziwa, B., Runz, H., Numann, A., Shafqat, N., Kavanagh, K. L., Hammerling, G., Wanders, R. J. A., Shield, J. P. H., Wendel, U. & 9 others, Stern, D., Nawroth, P., Hoffmann, G. F., Bartram, C. R., Arnold, B., Bierhaus, A., Oppermann, U., Steinbeisser, H. & Zschocke, J., 2010, In : Embo Molecular Medicine. 2, 2, p. 51-62

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A novel approach to improve stress regulation among traumatized youth in residential care: Feasibility study testing three game-based meditation interventions

Schuurmans, A. A. T., Nijhof, K. S., Scholte, R., Popma, A. & Otten, R., 10 Sep 2019, In : Early Intervention in Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

A novel classification system for research reporting in rare and progressive genetic conditions

van Karnebeek, C. D. M., Beumer, D., Pawliuk, C., Goez, H., Mostafavi, S., Andrews, G., Steele, R. & Siden, H., 1 Oct 2019, In : Developmental Medicine and Child Neurology. 61, 10, p. 1208-1213

Research output: Contribution to journalArticleAcademicpeer-review

A novel complex neurological phenotype due to a homozygous mutation in FDX2

Gurgel-Giannetti, J., Lynch, D. S., Brandão de Paiva, A. R., Lucato, L. T., Yamamoto, G., Thomsen, C., Basu, S., Freua, F., Giannetti, A. V., Ripa de Assis, B. D., Ospedale Ribeiro, M. D., Barcelos, I., Souza, K. S., Monti, F., Melo, U. S., Amorim, S., Silva, L. G. L., Macedo-Souza, L. C. I., Vianna-Morgante, A. M., Hirano, M. & 6 others, van der Knaap, M. S., Lill, R., Vainzof, M., Oldfors, A., Houlden, H. & Kok, F., 2018, In : Brain. 141, 8, p. 2289-2298

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Open Access

A novel cryptic CBFB-MYH11 gene fusion present at birth leading to acute myeloid leukemia and allowing molecular monitoring for minimal residual disease

Poddighe, P. J., Veening, M. A., Mansur, M. B., Loonen, A. H., Westers, T. M., Merle, P. A., Wessels, J. W., de Haas, V., Kors, W. A., Bhola, S. L., Wondergem, M. J., Ford, A. M. & Kaspers, G. J. L., 1 Mar 2018, In : Human Pathology: Case Reports. 11, p. 34-38 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

A novel familial case of diffuse leukodystrophy related to NDUFV1 compound heterozygous mutations

Ortega-Recalde, O., Fonseca, D. J., Patino, L. C., Atuesta, J. J., Rivera-Nieto, C., Restrepo, C. M., Mateus, H. E., van der Knaap, M. S. & Laissue, P., 2013, In : Mitochondrion. 13, 6, p. 749-754

Research output: Contribution to journalArticleAcademicpeer-review

A novel flow cytometry-based platelet aggregation assay

De Cuyper, I. M., Meinders, M., van de Vijver, E., de Korte, D., Porcelijn, L., de Haas, M., Eble, J. A., Seeger, K., Rutella, S., Pagliara, D., Kuijpers, T. W., Verhoeven, A. J., van den Berg, T. K. & Gutiérrez, L., 7 Mar 2013, In : Blood. 121, 10, p. e70-80

Research output: Contribution to journalArticleAcademicpeer-review

A Novel GJC2 Mutation Associated with Hypomyelination and Mullerian Agenesis Syndrome: Coincidence or a New Entity?

Yalcinkaya, C., Erturk, O., Tuysuz, B., Yesil, G., Verbeke, J. I. M. L., Keyser, B., Stuhrmann, M., Steinemann, D., Sistermans, E. A. & van der Knaap, M. S., 2012, In : Neuropediatrics. 43, 3, p. 159-161

Research output: Contribution to journalArticleAcademicpeer-review

A novel splice variant of FcγRIIa: a risk factor for anaphylaxis in patients with hypogammaglobulinemia

van der Heijden, J., Geissler, J., van Mirre, E., van Deuren, M., van der Meer, J. W. M., Salama, A., van den Berg, T. K., Roos, D. & Kuijpers, T. W., May 2013, In : Journal of Allergy and Clinical Immunology. 131, 5, p. 1408-16.e5

Research output: Contribution to journalArticleAcademicpeer-review

An Overview of L-2-Hydroxyglutarate Dehydrogenase Gene (L2HGDH) Variants: A Genotype-Phenotype Study

Steenweg, M. E., Jakobs, C., Errami, A., van Dooren, S. J. M., Bartolome, M. T. A., Aerssens, P., Baric, I., Baumann, M., Bonafe, L., Chabrol, B., Clarke, J. T. R., Clayton, P., Coker, M., Cooper, S., Falik-Zaccai, T., Gorman, M., Hahn, A., Hasanoglu, A., King, M. D., de Klerk, H. B. C. & 30 others, Korman, S. H., Lee, C., Lund, A. M., Mejaski-Bosnjak, V., Pascual-Castroviejo, I., Raadhyaksha, A., Rootwelt, T., Roubertie, A., Ruiz-Falco, M. L., Scalais, E., Schimmel, U., Seijo-Martinez, M., Suri, M., Sykut-Cegielska, J., Trefz, F. K., Uziel, G., Valayannopoulos, V., Vianey-Saban, C., Vlaho, S., Vodopiutz, J., Wajner, M., Walter, J., Walter-Derbort, C., Yapici, Z., Zafeiriou, D. I., Spreeuwenberg, M. D., Celli, J., den Dunnen, J. T., van der Knaap, M. S. & Salomons, G. S., 2010, In : Human Mutation. 31, 4, p. 380-390

Research output: Contribution to journalArticleAcademicpeer-review

Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); a randomized double blind placebo controlled multicenter study

Kaandorp, J. J., Benders, M. J. N. L., Rademaker, C. M. A., Torrance, H. L., Oudijk, M. A., Haan, T. R., Bloemenkamp, K. M., Rijken, M., van Pampus, M. G., Bos, A. F., Porath, M. M., Oetomo, S. B., Willekes, C., Gavilanes, A. W. D., Wouters, M. G. A. J., van Elburg, R. M., Huisjes, A. J. M., Bakker, S. C. M. J., van Meir, C. A., von Lindern, J. & 9 others, Boon, J., de Boer, I. P., Rijnders, R. J. P., Jacobs, C. W. F., Uiterwaal, C. S. P. M., Mol, B. W. J., Visser, G. H. A., van Bel, F. & Derks, J. B., 2010, In : BMC Pregnancy and Childbirth. 10, p. 8 6 p.

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Antenatal glucocorticoid treatment is not associated with long-term metabolic risks in individuals born before 32 weeks of gestation

Finken, M. J. J., Keijzer-Veen, M. G., Dekker, F. W., Frolich, M., Walther, F. J., Romijn, J. A., van der Heijden, B. J. & Wit, J. M., 2008, In : Archives of Disease in Childhood-Fetal and Neonatal Edition. 93, 6, p. F442-F447

Research output: Contribution to journalArticleAcademicpeer-review

Antenatal maternal anxiety is associated with problem behaviour at age five

Loomans, E. M., van der Stelt, O., van Eijsden, M., Gemke, R. J. B. J., Vrijkotte, T. & Van den Bergh, B. R. H., 2011, In : Early Human Development. 87, 8, p. 565-570

Research output: Contribution to journalArticleAcademicpeer-review

Antenatal Workup of Early Megacystis and Selection of Candidates for Fetal Therapy

Fontanella, F., Duin, L., Adama van Scheltema, P. N., Cohen-Overbeek, T. E., Pajkrt, E., Bekker, M., Willekes, C., Bax, C. J., Oepkes, D. & Bilardo, C. M., 1 Mar 2019, In : Fetal Diagnosis and Therapy. 45, 3, p. 155-161

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Open Access

Antibiotic prophylaxis does not reduce the infection rate following percutaneous endoscopic gastrostomy in infants and children

van Els, A. L., van Driel, J. J., Kneepkens, C. M. F. & de Meij, T. G. J., May 2017, In : Acta Paediatrica. 106, 5, p. 801-805

Research output: Contribution to journalArticleAcademicpeer-review

Antibodies pay Toll to improve their therapeutic efficacy: improving antibody-mediated anticancer treatment via co-activation of Fc-receptors and Toll-like receptors

Ganzevles, S., Stigter-van Walsum, M., Schilham, M., Tuk, K., van Egmond, M., Leemans, R., Brakenhoff, R. & Bakema, J., Aug 2016, In : European Journal of Immunology. 46, p. 204-204

Research output: Contribution to journalArticleAcademicpeer-review

Anti-CD14 monoclonal antibodies inhibit the production of tumor necrosis factor alpha and interleukin-10 by human monocytes stimulated with killed and live Haemophilus influenzae or Streptococcus pneumoniae organisms

Van Furth, A. M., Verhard-Seijmonsbergen, E. M., Langermans, J. A. M., Van Dissel, J. T. & Van Furth, R., 1 Aug 1999, In : Infection and Immunity. 67, 8, p. 3714-3718 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Anticipated Reward in Obsessive-Compulsive Disorder: Are Compulsions Rewarding?

Fontenelle, L. F., Oostermeijer, S., Ferreira, G. M., Lorenzetti, V., Luigjes, J. & Yucel, M., 2015, In : Journal of Clinical Psychiatry. 76, 9, p. E1134-E1135

Research output: Contribution to journalArticleAcademicpeer-review

Antileukemic Activity and Mechanism of Drug Resistance to the Marine Salinispora tropica Proteasome Inhibitor Salinosporamide A (Marizomib)

Niewerth, D., Jansen, G., Riethoff, L. F. V., van Meerloo, J., Kale, A. J., Moore, B. S., Assaraf, Y. G., Anderl, J. L., Zweegman, S., Kaspers, G. J. L. & Cloos, J., 2014, In : Molecular Pharmacology. 86, 1, p. 12-19

Research output: Contribution to journalArticleAcademicpeer-review

Anti-leukemic activity and mechanisms underlying resistance to the novel immunoproteasome inhibitor PR-924

Niewerth, D., van Meerloo, J., Jansen, G., Assaraf, Y. G., Hendrickx, T. C., Kirk, C. J., Anderl, J. L., Zweegman, S., Kaspers, G. J. L. & Cloos, J., 2014, In : Biochemical Pharmacology. 89, 1, p. 43-51

Research output: Contribution to journalArticleAcademicpeer-review

Antiretroviral treatment and time since HIV-1 diagnosis are associated with large artery stiffness in sub-Saharan African HIV-1 patients

Msoka, T. F., Van Guilder, G. P., Smulders, Y. M., van Furth, M., Bartlett, J. A. & van Agtmael, M. A., Dec 2016, In : Artery Research. 16, p. 34-41

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Antisocial Behavior and Victimization Over 2-Year Follow-Up in Subgroups of Childhood Arrestees

van Domburgh, L., Geluk, C., Jansen, L., Vermeiren, R. & Doreleijers, T., 2019, In : Journal of Interpersonal Violence. 34, 18, p. 3780-3806

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Anti-TNFα Treatment After Surgical Resection for Crohn's Disease Is Effective Despite Previous Pharmacodynamic Failure

Assa, A., Bronsky, J., Kolho, K-L., Zarubova, K., de Meij, T., Ledder, O., Sladek, M., van Biervliet, S., Strisciuglio, C. & Shamir, R., May 2017, In : Inflammatory Bowel Diseases. 23, 5, p. 791-797 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

An unusual hotspot in a young woman with Hodgkin's lymphoma

ten Hove, C. H., Zijlstra-Baalbergen, J. M., Comans, E. F. I. & van Elburg, R. M., 2008, In : Haematologica. 93, 1, p. e14-e15

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An unusually mild presentation of megalencephalic leukoencephalopathy with subcortical cysts

Kocaman, G., Eryigit, G., Abbink, G. E. M., Kilicarslan, R., Asil, T., Alkan, A., van der Knaap, M. S. & Kocer, A., 2013, In : Clinical Neurology and Neurosurgery. 115, 8, p. 1564-1566

Research output: Contribution to journalArticleAcademicpeer-review

An UPLC-MS detection method for the quantification of five antibiotics in human plasma

Chahbouni, A., van den Dungen, F. A. M., Vos, R. M., den Burger, J. C. G., Sinjewel, A., Wilhelm, A. J., Veldkamp, A. I., Swart, E. L. & van Weissenbruch, M. M., 2015, In : Bioanalysis. 7, 18, p. 2321-2329

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Anuria in a solitary kidney with Candida bezoars managed conservatively

Schilperoort, J. V., de Wall, L. L., van der Horst, H. J. R., van Wijk, J. A. E., Verbeke, J. I. M. L. & Bokenkamp, A., 2014, In : European Journal of Pediatrics. 173, 12, p. 1623-1625

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Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity

van der Meer, D., Hoekstra, P. J., van Rooij, D., Winkler, A. M., van Ewijk, H., Heslenfeld, D. J., Oosterlaan, J., Faraone, S. V., Franke, B., Buitelaar, J. K. & Hartman, C. A., 2018, In : World Journal of Biological Psychiatry. 19, 6, p. 450-460

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Open Access

Aortic elasticity and size are associated with aortic regurgitation and left ventricular dysfunction in tetralogy of Fallot after pulmonary valve replacement

Grotenhuis, H. B., Ottenkamp, J., de Bruijn, L., Westenberg, J. J. M., Vliegen, H. W., Kroft, L. J. M. & de Roos, A., 2009, In : Heart. 95, 23, p. 1931-1936

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A paced visual serial addition test for fMRI

Lazeron, R. H. C., Rombouts, S. A. R. B., De Sonneville, L., Barkhof, F. & Scheltens, P., 15 Sep 2003, In : Journal of the Neurological Sciences. 213, 1-2, p. 29-34 6 p.

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A Patient With a Mild Holoprosencephaly Spectrum Phenotype and Heterotaxy and a 1.3 Mb Deletion Encompassing GLI2

Kevelam, S. H. G., van Harssel, J. J., van der Zwaag, B., Smeets, H. J., Paulussen, A. D. & Lichtenbelt, K. D., 2012, In : American Journal of Medical Genetics Part A. 158A, 1, p. 166-173

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Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality. A new therapeutic approach to treat gram-negative sepsis

Van Oosten, M., Rensen, P. C., Van Amersfoort, E. S., Van Eck, M., Van Dam, A. M., Breve, J. J., Vogel, T., Panet, A., Van Berkel, T. J. & Kuiper, J., 23 Mar 2001, In : Journal of Biological Chemistry. 276, 12, p. 8820-4 5 p.

Research output: Contribution to journalArticleAcademicpeer-review