Research Output 1997 2020

2020

Long noncoding RNAs in key cellular processes involved in aortic aneurysms

Wu, Z., Trenner, M., Boon, R. A., Spin, J. M. & Maegdefessel, L., 2020, In : Atherosclerosis. 292, p. 112-118

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Pharmacological interventions to reduce edema following cardiopulmonary bypass: A systematic review and meta-analysis

Dekker, N. A. M., van Leeuwen, A. L. I., van de Ven, P. M., de Vries, R., Hordijk, P. L., Boer, C. & van den Brom, C. E., 2020, In : Journal of Critical Care. 56, p. 63-72 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2019

6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling

Kurakula, K., Sun, X-Q., Happé, C., da Silva Goncalves Bos, D., Szulcek, R., Schalij, I., Wiesmeijer, K., Lodder, K., Tu, L., Guignabert, C., de Vries, C. J., de Man, F., Noordegraaf, A. V., Ten Dijke, P., Goumans, M-J. & Bogaard, H. J., 2019, In : The European respiratory journal.

Research output: Contribution to journalArticleAcademicpeer-review

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury

Barefield, D. Y., McNamara, J. W., Lynch, T. L., Kuster, D. W. D., Govindan, S., Haar, L., Wang, Y., Taylor, E. N., Lorenz, J. N., Nieman, M. L., Zhu, G., Luther, P. K., Varró, A., Dobrev, D., Ai, X., Janssen, P. M. L., Kass, D. A., Jones, W. K., Gilbert, R. J. & Sadayappan, S., 1 Apr 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 236-246 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Global Loss of Dio2 Leads to Unexpected Changes in Function and Fiber Types of Slow Skeletal Muscle in Male Mice

Carmody, C., Ogawa-Wong, A. N., Martin, C., Luongo, C., Zuidwijk, M., Sager, B., Petersen, T., Roginski Guetter, A., Janssen, R., Wu, E. Y., Bogaards, S., Neumann, N. M., Hau, K., Marsili, A., Boelen, A., Silva, J. E., Dentice, M., Salvatore, D., Wagers, A. J., Larsen, P. R. & 2 othersSimonides, W. S. & Zavacki, A. M., 1 Jan 2019, In : Endocrinology. 160, 5, p. 1205-1222

Research output: Contribution to journalArticleAcademicpeer-review

A randomised comparison of the effect of haemodynamic monitoring with CardioMEMS in addition to standard care on quality of life and hospitalisations in patients with chronic heart failure: Design and rationale of the MONITOR HF multicentre randomised clinical trial

Brugts, J. J., Veenis, J. F., Radhoe, S. P., Linssen, G. C. M., van Gent, M., Borleffs, C. J. W., van Ramshorst, J., van Pol, P., Tukkie, R., Spee, R. F., Emans, M. E., Kok, W., van Halm, V., Handoko, L., Beeres, S. L. M. A., Post, M. C., Boersma, E., Lenzen, M. J., Manintveld, O. C., Koffijberg, H. & 10 othersvan Baal, P., Versteegh, M., Smilde, T. D., van Heerebeek, L., Rienstra, M., Mosterd, A., Delnoy, P. P. H., Asselbergs, F. W., Brunner-la Rocca, H. P. & de Boer, R. A., 2019, In : Netherlands Heart Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Bosutinib Protects against Vascular Leakage by Improving Endothelial Cell-Matrix Adhesion

Botros, L., Pronk, M., Juschten, J., Liddle, J., Tuinman, P. R., van Bezu, J., Huveneers, S., Bogaard, H. J., van Hinsbergh, V., Hordijk, P. & Aman, J., 2019, In : Journal of Vascular Research. 56, p. 15-15

Research output: Contribution to journalMeeting AbstractAcademic

Cardiac Disorders and Pathophysiology of Sarcomeric Proteins

van der Velden, J. & Stienen, G. J. M., 1 Jan 2019, In : Physiological Reviews. 99, 1, p. 381-426 46 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin

Juni, R. P., Kuster, D. W. D., Goebel, M., Helmes, M., Musters, R. J. P., van der Velden, J., Koolwijk, P., Paulus, W. J. & van Hinsbergh, V. W. M., 1 Sep 2019, In : JACC: Basic to Translational Science. 4, 5, p. 575-591

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cardiac remodelling in a swine model of chronic thromboembolic pulmonary hypertension: comparison of right vs. left ventricle

Stam, K., Cai, Z., van der Velde, N., van Duin, R., Lam, E., van der Velden, J., Hirsch, A., Duncker, D. J. & Merkus, D., 1 Sep 2019, In : Journal of Physiology. 597, 17, p. 4465-4480

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cardiomyocyte calcineurin is required for the onset and progression of cardiac hypertrophy and fibrosis in adult mice

Martínez-Martínez, S., Lozano-Vidal, N., López-Maderuelo, M. D., Jiménez-Borreguero, L. J., Armesilla, Á. L. & Redondo, J. M., 1 Jan 2019, In : FEBS Journal. 286, 1, p. 46-65

Research output: Contribution to journalArticleAcademicpeer-review

Contrast-enhanced ultrasound for quantification of tissue perfusion in humans

Emanuel, A. L., Meijer, R. I., van Poelgeest, E., Spoor, P., Serné, E. H. & Eringa, E. C., 1 Jan 2019, In : Microcirculation. e12588.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Open Access

CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity

Majolée, J., Pronk, M. C. A., Jim, K. K., van Bezu, J. S. M., van der Sar, A. M., Hordijk, P. L. & Kovačević, I., 1 Dec 2019, In : Scientific Reports. 9, 1, 8131.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diaphragm contractile weakness due to reduced mechanical loading: Role of titin

van der Pijl, R. J., Granzier, H. L. & Ottenheijm, C. A. C., 1 Aug 2019, In : American Journal of Physiology: Cell Physiology. 317, 2, p. C167-C176

Research output: Contribution to journalArticleAcademicpeer-review

Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model

Waddingham, M. T., Sonobe, T., Tsuchimochi, H., Edgley, A. J., Sukumaran, V., Chen, Y. C., Hansra, S. S., Schwenke, D. O., Umetani, K., Aoyama, K., Yagi, N., Kelly, D. J., Gaderi, S., Herwig, M., Kolijn, D., Mügge, A., Paulus, W. J., Ogo, T., Shirai, M., Hamdani, N. & 1 othersPearson, J. T., 2019, In : Journal of Molecular and Cellular Cardiology. 137, p. 119-131

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

DISRUPTED CELLULAR BARRIERS IN KIDNEY FAILURE: The endothelium and the peritoneal membrane

Vila Cuenca, M., 2019, 222 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Open Access

Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction

Miranda-Silva, D., Wüst, R. C. I., Conceição, G., Gonçalves-Rodrigues, P., Gonçalves, N. D., Gonçalves, A., Kuster, D. W. D., Leite-Moreira, A. F., van der Velden, J., de Sousa Beleza, J. M., Magalhães, J., Stienen, G. J. M. & Falcão-Pires, I., 2019, In : Acta Physiologica. e13378.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes

Noll, B., Benz, D., Frey, Y., Meyer, F., Lauinger, M., Eisler, S. A., Schmid, S., Hordijk, P. L. & Olayioye, M. A., 2019, In : Journal of Cell Science. 132, 11, jcs223172.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation

Zhang, D., Hu, X., Li, J., Liu, J., Baks-Te Bulte, L., Wiersma, M., Malik, N-U-A., van Marion, D. M. S., Tolouee, M., Hoogstra-Berends, F., Lanters, E. A. H., van Roon, A. M., de Vries, A. A. F., Pijnappels, D. A., de Groot, N. M. S., Henning, R. H. & Brundel, B. J. J. M., 1 Dec 2019, In : Nature Communications. 10, 1, 1307.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effects of levosimendan on respiratory muscle function in patients weaning from mechanical ventilation

Roesthuis, L., van der Hoeven, H., Sinderby, C., Frenzel, T., Ottenheijm, C., Brochard, L., Doorduin, J. & Heunks, L., Oct 2019, In : Intensive Care Medicine. 45, 10, p. 1372-1381 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α-Stimulated Human Coronary Arterial Endothelial Cells

Uthman, L., Homayr, A., Juni, R. P., Spin, E. L., Kerindongo, R., Boomsma, M., Hollmann, M. W., Preckel, B., Koolwijk, P., van Hinsbergh, V. W. M., Zuurbier, C. J., Albrecht, M. & Weber, N. C., 2019, In : Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 53, 5, p. 865-886

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

End-diastolic force pre-activates cardiomyocytes and determines contractile force: role of titin and calcium

Najafi, A., van de Locht, M., Schuldt, M., Schönleitner, P., van Willigenburg, M., Bollen, I., Goebel, M., Ottenheijm, C. A. C., van der Velden, J., Helmes, M. & Kuster, D. W. D., 1 Sep 2019, In : Journal of Physiology. 597, 17, p. 4521-4531

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Expiratory muscle dysfunction in critically ill patients: towards improved understanding

Shi, Z-H., Jonkman, A., de Vries, H., Jansen, D., Ottenheijm, C., Girbes, A., Spoelstra-de Man, A., Zhou, J-X., Brochard, L. & Heunks, L., 2019, In : Intensive Care Medicine.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Extracellular SPARC increases cardiomyocyte contraction during health and disease

Deckx, S., Johnson, D. M., Rienks, M., Carai, P., van Deel, E., van der Velden, J., Sipido, K. R., Heymans, S. & Papageorgiou, A-P., 1 Apr 2019, In : PLoS ONE. 14, 4, e0209534.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Extra energy for hearts with a genetic defect: ENERGY trial

van Driel, B. O., van Rossum, A. C., Michels, M., Huurman, R. & van der Velden, J., 2019, In : Netherlands Heart Journal. 27, 4, p. 200-205 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Extravasation of Microspheres in a Rat Model of Silent Brain Infarcts

van der Wijk, A-E., Lachkar, N., de Vos, J., Grootemaat, A. E., van der Wel, N. N., Hordijk, P. L., Bakker, E. N. T. P. & vanBavel, E., 1 Jan 2019, In : Stroke. 50, 6, p. 1590-1594

Research output: Contribution to journalArticleAcademicpeer-review

F8-IL10: a new potential anti-rheumatic drug evaluated by a PET-guided translational approach

Bruijnen, S. T. G., Chandrupatla, D. M. S. H., Giovanonni, L., Neri, D., Vugts, D. J., Huisman, M. C., Hoekstra, O. S., Musters, R. J. P., Lammertsma, A. A., van Dongen, G. A. M. S., Jansen, G., Molthoff, C. F. M. & van der Laken, C. J., 7 Jan 2019, In : Molecular Pharmaceutics. 16, 1, p. 273-281

Research output: Contribution to journalArticleAcademicpeer-review

FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB

Pronk, M. C. A., Majolée, J., Loregger, A., van Bezu, J. S. M., Zelcer, N., Hordijk, P. L. & Kovačević, I., 1 Mar 2019, In : Molecular Biology of the Cell. 30, 5, p. 607-621 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Five-year prognostic significance of global longitudinal strain in individuals with a hypertrophic cardiomyopathy gene mutation without hypertrophic changes

van Velzen, H. G., Schinkel, A. F. L., van Grootel, R. W. J., van Slegtenhorst, M. A., van der Velden, J., Strachinaru, M. & Michels, M., 2019, In : Netherlands Heart Journal. 27, 3, p. 117-126 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology

Wiersma, V. I., van Ziel, A. M., Vazquez-Sanchez, S., Nölle, A., Berenjeno-Correa, E., Bonaterra-Pastra, A., Clavaguera, F., Tolnay, M., Musters, R. J. P., van Weering, J. R. T., Verhage, M., Hoozemans, J. J. M. & Scheper, W., 2019, In : Acta Neuropathologica.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation

Cremer, S., Michalik, K. M., Fischer, A., Pfisterer, L., Jaé, N., Winter, C., Boon, R. A., Muhly-Reinholz, M., John, D., Uchida, S., Weber, C., Poller, W., Günther, S., Braun, T., Li, D. Y., Maegdefessel, L., Perisic Matic, L., Hedin, U., Soehnlein, O., Zeiher, A. & 1 othersDimmeler, S., 5 Mar 2019, In : Circulation. 139, 10, p. 1320-1334 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Hypertrofische cardiomyopathie

van Driel, B., Asselbergs, F. W., de Boer, R. A., van Rossum, A. C., van Tintelen, J. P., van der Velden, J. & Michels, M., 2019, In : Nederlands Tijdschrift voor Geneeskunde. 163, 8, D2790.

Research output: Contribution to journalArticleProfessional

Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits

Wijnker, P. J. M., Sequeira, V., Kuster, D. W. D. & van der Velden, J., 1 Aug 2019, In : Antioxidants and Redox Signaling. 31, 4, p. 318-358

Research output: Contribution to journalReview articleAcademicpeer-review

Hypertrophic Cardiomyopathy - Need for Gene-Specific Treatment?

van Driel, B. & van der Velden, J., 1 Aug 2019, In : JAMA cardiology. 4, 8, p. 831-832

Research output: Contribution to journalComment/Letter to the editorAcademic

Identification of guanine nucleotide exchange factors that increase Cdc42 activity in primary human endothelial cells

Reinhard, N. R., van der Niet, S., Chertkova, A., Postma, M., Hordijk, P. L., Gadella Jr, T. W. J. & Goedhart, J., 2019, In : Small GTPases.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

IL-6 counteracts the inhibitory effect of IL-4 on osteogenic differentiation of human adipose stem cells

Bastidas-Coral, A. P., Hogervorst, J. M. A., Forouzanfar, T., Kleverlaan, C. J., Koolwijk, P., Klein-Nulend, J. & Bakker, A. D., 1 Nov 2019, In : Journal of Cellular Physiology. 234, 11, p. 20520-20532 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Increasing sensitivity—a common-sense approach?

Michels, M., Asselbergs, F. W. & van der Velden, J., 1 Jun 2019, In : Netherlands Heart Journal. 27, 6, p. 287-288

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1

Pei, J., Juni, R., Harakalova, M., Duncker, D. J., Asselbergs, F. W., Koolwijk, P., van Hinsbergh, V. W. M., Verhaar, M. C., Mokry, M. & Cheng, C., 2019, In : Toxins. 11, 8, 454.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Integrative Functional Annotation of 52 Genetic Loci Influencing Myocardial Mass Identifies Candidate Regulatory Variants and Target Genes

Hemerich, D., Pei, J., Harakalova, M., van Setten, J., Boymans, S., Boukens, B. J., Efimov, I. R., Michels, M., van der Velden, J., Vink, A., Cheng, C., van der Harst, P., Moore, J. H., Mokry, M., Tragante, V. & Asselbergs, F. W., 1 Feb 2019, In : Circulation. Genomic and precision medicine. 12, 2, p. 76-83 8 p., e002328.

Research output: Contribution to journalArticleAcademicpeer-review

JNK2 in myeloid cells impairs insulin's vasodilator effects in muscle during early obesity development through perivascular adipose tissue dysfunction

Meijer, R. I., Hoevenaars, F. P. M., Serné, E. H., Yudkin, J. S., Kokhuis, T. J. A., Weijers, E. M., van Hinsbergh, V. W. M., Smulders, Y. M. & Eringa, E. C., 1 Aug 2019, In : American Journal of Physiology. Heart and Circulatory Physiology. 317, 2, p. H364-H374

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Long non-coding RNA H19 regulates endothelial cell aging via inhibition of STAT3 signalling

Hofmann, P., Sommer, J., Theodorou, K., Kirchhof, L., Fischer, A., Li, Y., Perisic, L., Hedin, U., Maegdefessel, L., Dimmeler, S. & Boon, R. A., 1 Jan 2019, In : Cardiovascular Research. 115, 1, p. 230-242 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Long non-coding RNA in vascular disease and aging

Bink, D. I., Lozano-Vidal, N. & Boon, R. A., 1 Jan 2019, In : Non-coding RNA. 5, 1, 26.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Mechanisms leading to muscle weakness in Nemaline myopathy

Joureau, B., 2019, 204 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Open Access