Research Output per year
Research Output 1997 2019
- 1 - 50 out of 941 results
- Publication Year, Title (descending)
2019
6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling
Kurakula, K., Sun, X-Q., Happé, C., da Silva Goncalves Bos, D., Szulcek, R., Schalij, I., Wiesmeijer, K. C., Lodder, K., Tu, L., Guignabert, C., de Vries, C. J. M., de Man, F. S., Noordegraaf, A. V., Ten Dijke, P., Goumans, M-J. & Bogaard, H. J., 4 Jul 2019, In : The European respiratory journal.Research output: Contribution to journal › Article › Academic › peer-review
Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury
Barefield, D. Y., McNamara, J. W., Lynch, T. L., Kuster, D. W. D., Govindan, S., Haar, L., Wang, Y., Taylor, E. N., Lorenz, J. N., Nieman, M. L., Zhu, G., Luther, P. K., Varró, A., Dobrev, D., Ai, X., Janssen, P. M. L., Kass, D. A., Jones, W. K., Gilbert, R. J. & Sadayappan, S., 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 236-246Research output: Contribution to journal › Article › Academic › peer-review
Open Access
DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes
Noll, B., Benz, D., Frey, Y., Meyer, F., Lauinger, M., Eisler, S. A., Schmid, S., Hordijk, P. L. & Olayioye, M. A., 2019, In : Journal of Cell Science. 132, 11Research output: Contribution to journal › Article › Academic › peer-review
Open Access
DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation
Zhang, D., Hu, X., Li, J., Liu, J., Baks-Te Bulte, L., Wiersma, M., Malik, N-U-A., van Marion, D. M. S., Tolouee, M., Hoogstra-Berends, F., Lanters, E. A. H., van Roon, A. M., de Vries, A. A. F., Pijnappels, D. A., de Groot, N. M. S., Henning, R. H. & Brundel, B. J. J. M., 21 Mar 2019, In : Nature Communications. 10, 1, 1307.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Evolution of heterotopic bone in fibrodysplasia ossificans progressiva: An [18F]NaF PET/CT study
Botman, E., Raijmakers, P. G. H. M., Yaqub, M., Teunissen, B., Netelenbos, C., Lubbers, W., Schwarte, L. A., Micha, D., Bravenboer, N., Schoenmaker, T., de Vries, T. J., Pals, G., Smit, J. M., Koolwijk, P., Trotter, D. G., Lammertsma, A. A. & Eekhoff, E. M. W., 2019, In : Bone. 124, p. 1-6Research output: Contribution to journal › Article › Academic › peer-review
EXPRESS: Preserving right ventricular function in patients with pulmonary arterial hypertension: single centre experience with a cardiac magnetic resonance imaging-guided treatment strategy
Huis In 't Veld, A. E., Van de Veerdonk, M. C., Spruijt, O., Groeneveldt, J. A., Marcus, J. T., Westerhof, N., Bogaard, H. J. & Vonk-Noordegraaf, A., 11 Jan 2019, In : Pulmonary Circulation. p. 2045894018824553Research output: Contribution to journal › Article › Academic › peer-review
Extra energy for hearts with a genetic defect: ENERGY trial
van Driel, B. O., van Rossum, A. C., Michels, M., Huurman, R. & van der Velden, J., 2019, In : Netherlands Heart Journal. 27, 4, p. 200-205Research output: Contribution to journal › Article › Academic › peer-review
Open Access
F8-IL10: a new potential anti-rheumatic drug evaluated by a PET-guided translational approach
Bruijnen, S. T. G., Chandrupatla, D. M. S. H., Giovanonni, L., Neri, D., Vugts, D. J., Huisman, M. C., Hoekstra, O. S., Musters, R. J. P., Lammertsma, A. A., van Dongen, G. A. M. S., Jansen, G., Molthoff, C. F. M. & van der Laken, C. J., Jan 2019, In : Molecular Pharmaceutics. 16, 1, p. 273-281Research output: Contribution to journal › Article › Academic › peer-review
FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB
Pronk, M. C. A., Majolée, J., Loregger, A., van Bezu, J. S. M., Zelcer, N., Hordijk, P. L. & Kovačević, I., 1 Mar 2019, In : Molecular Biology of the Cell. 30, 5, p. 607-621 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Five-year prognostic significance of global longitudinal strain in individuals with a hypertrophic cardiomyopathy gene mutation without hypertrophic changes
van Velzen, H. G., Schinkel, A. F. L., van Grootel, R. W. J., van Slegtenhorst, M. A., van der Velden, J., Strachinaru, M. & Michels, M., 2019, In : Netherlands Heart Journal. 27, 3, p. 117-126Research output: Contribution to journal › Article › Academic › peer-review
Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation
Cremer, S., Michalik, K. M., Fischer, A., Pfisterer, L., Jaé, N., Winter, C., Boon, R. A., Muhly-Reinholz, M., John, D., Uchida, S., Weber, C., Poller, W., Günther, S., Braun, T., Li, D. Y., Maegdefessel, L., Perisic Matic, L., Hedin, U., Soehnlein, O., Zeiher, A. & 1 others, 2019, In : Circulation. 139, 10, p. 1320-1334 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Homocysteine-induced inverse expression of tissue factor and DPP4 in endothelial cells is related to NADPH oxidase activity
Korkmaz, H. I., Hahn, N. E., Jansen, K. M., Musters, R. J. P., van Bezu, J., van Wieringen, W. N., van Zuijlen, P. P. M., Ulrich, M. M. W., Niessen, H. W. M. & Krijnen, P. A. J., 2019, In : Physiology International. 106, 1, p. 29-38 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Hypertrofische cardiomyopathie
van Driel, B., Asselbergs, F. W., de Boer, R. A., van Rossum, A. C., van Tintelen, J. P., van der Velden, J. & Michels, M., 2019, In : Nederlands Tijdschrift voor Geneeskunde. 163, 8, D2790.Research output: Contribution to journal › Article › Professional
IL-6 counteracts the inhibitory effect of IL-4 on osteogenic differentiation of human adipose stem cells
Bastidas-Coral, A. P., Hogervorst, J. M. A., Forouzanfar, T., Kleverlaan, C. J., Koolwijk, P., Klein-Nulend, J. & Bakker, A. D., 2019, In : Journal of Cellular Physiology. 234, 11, p. 20520-20532Research output: Contribution to journal › Article › Academic › peer-review
Impaired smooth muscle cell contractility as a novel concept of abdominal aortic aneurysm pathophysiology
Bogunovic, N., Meekel, J. P., Micha, D., Blankensteijn, J. D., Hordijk, P. L. & Yeung, K. K., 2019, In : Scientific Reports. 9, 1, 6837.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Integrative Functional Annotation of 52 Genetic Loci Influencing Myocardial Mass Identifies Candidate Regulatory Variants and Target Genes
Hemerich, D., Pei, J., Harakalova, M., van Setten, J., Boymans, S., Boukens, B. J., Efimov, I. R., Michels, M., van der Velden, J., Vink, A., Cheng, C., van der Harst, P., Moore, J. H., Mokry, M., Tragante, V. & Asselbergs, F. W., 25 Jan 2019, In : Circulation. Genomic and precision medicine.Research output: Contribution to journal › Article › Academic › peer-review
Long non-coding RNA H19 regulates endothelial cell aging via inhibition of STAT3 signalling
Hofmann, P., Sommer, J., Theodorou, K., Kirchhof, L., Fischer, A., Li, Y., Perisic, L., Hedin, U., Maegdefessel, L., Dimmeler, S. & Boon, R. A., 2019, In : Cardiovascular Research. 115, 1, p. 230-242Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Mechanistic Links Between Obesity, Diabetes, and Blood Pressure: Role of Perivascular Adipose Tissue
Saxton, S. N., Clark, B. J., Withers, S. B., Eringa, E. C. & Heagerty, A. M., 2019, In : Physiological Reviews. 99, 4, p. 1701-1763Research output: Contribution to journal › Article › Academic › peer-review
Meijer and Vloedman's histochemical demonstration of mitochondrial coupling obeys Lambert-Beer's law in the myocardium
Peters, E. L., Comerford, D., Vaz, F. M. & van der Laarse, W. J., 29 Jan 2019, In : Histochemistry and Cell Biology. 151, 1, p. 85-90 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels
Dekker, N. A. M., van Leeuwen, A. L. I., van Strien, W. W. J., Majolée, J., Szulcek, R., Vonk, A. B. A., Hordijk, P. L., Boer, C. & van den Brom, C. E., 2019, In : Critical Care. 23, 1, 117.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Muscle fiber dysfunction contributes to weakness in inclusion body myositis
Lassche, S., Rietveld, A., Heerschap, A., van Hees, H. W., Hopman, M. T. E., Voermans, N. C., Saris, C. G. J., van Engelen, B. G. M. & Ottenheijm, C. A. C., 2019, In : Neuromuscular Disorders.Research output: Contribution to journal › Article › Academic › peer-review
Muscle weakness in a S. pneumoniae sepsis mouse model
Witteveen, E., Wieske, L., Manders, E., Verhamme, C., Ottenheijm, C. A. C., Schultz, M. J., van Schaik, I. N. & Horn, J., Jan 2019, In : Annals of Translational Medicine. 7, 1, 9.Research output: Contribution to journal › Article › Academic › peer-review
Myocardial adaptation after surgical therapy differs for aortic valve stenosis and hypertrophic obstructive cardiomyopathy
Parbhudayal, R. Y., Güçlü, A., Zweerink, A., Biesbroek, P. S., Croisille, P., Clarysse, P., Michels, M., Stooker, W., Vonk, A. B. A., van der Ven, P. M., van Rossum, A. C., van der Velden, J. & Nijveldt, R., 2019, In : International Journal of Cardiovascular Imaging.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension
Rol, N., de Raaf, M. A., Sun, X. Q., Kuiper, V. P., da Silva Gonçalves Bos, D., Happé, C., Kurakula, K., Dickhoff, C., Thuillet, R., Tu, L., Guignabert, C., Schalij, I., Lodder, K., Pan, X., Herrmann, F. E., van Nieuw Amerongen, G. P., Koolwijk, P., Vonk-Noordegraaf, A., de Man, F. S., Wollin, L. & 3 others, 2019, In : Cardiovascular Research. 115, 2, p. 432-439Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone
Andersen, S., Birkmose Axelsen, J., Ringgaard, S., Randel Nyengaard, J., Holm Nielsen, S., Genovese, F., Asser Karsdal, M., Adler Hyldebrandt, J., Brandt Sørensen, C., de Man, F. S., Jan Bogaard, H., Erik Nielsen-Kudsk, J. & Andersen, A., Apr 2019, In : Pulmonary Circulation. 9, 2, p. 204589401984865Research output: Contribution to journal › Article › Academic › peer-review
Recessive MYH7-related myopathy in two families
Beecroft, S. J., van de Locht, M., de Winter, J. M., Ottenheijm, C. A., Sewry, C. A., Mohammed, S., Ryan, M. M., Woodcock, I. R., Sanders, L., Gooding, R., Davis, M. R., Oates, E. C., Laing, N. G., Ravenscroft, G., McLean, C. A. & Jungbluth, H., 2019, In : Neuromuscular Disorders.Research output: Contribution to journal › Article › Academic › peer-review
Role of Noncoding RNAs in the Pathogenesis of Abdominal Aortic Aneurysm
Kumar, S., Boon, R. A., Maegdefessel, L., Dimmeler, S. & Jo, H., 2019, In : Circulation Research. 124, 4, p. 619-630Research output: Contribution to journal › Article › Academic › peer-review
Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation
van Marion, D. M. S., Hu, X., Zhang, D., Hoogstra-Berends, F., Seerden, J-P. G., Loen, L., Heeres, A., Steen, H., Henning, R. H. & Brundel, B. J. J. M., 2019, In : DRUG DESIGN DEVELOPMENT AND THERAPY. 13, p. 345-364Research output: Contribution to journal › Article › Academic › peer-review
Sex differences in hypertrophic cardiomyopathy: new insights
van Driel, B., Nijenkamp, L., Huurman, R., Michels, M. & van der Velden, J., 2019, In : Current opinion in cardiology. 34, 3, p. 254-259Research output: Contribution to journal › Article › Academic › peer-review
Stabilization of cell-cell junctions by active Vitamin D ameliorates uraemia-induced loss of human endothelial barrier function
Cuenca, M. V., van Bezu, J., Beelen, R. H. J., Vervloet, M. G. & Hordijk, P. L., 2019, In : Nephrology, Dialysis, Transplantation. 34, 2, p. 252-264 13 p.Research output: Contribution to journal › Article › Academic › peer-review
The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM
Piroddi, N., Witjas-Paalberends, E. R., Ferrara, C., Ferrantini, C., Vitale, G., Scellini, B., Wijnker, P. J. M., Sequiera, V., Dooijes, D., Dos Remedios, C., Schlossarek, S., Leung, M. C., Messer, A., Ward, D. G., Biggeri, A., Tesi, C., Carrier, L., Redwood, C. S., Marston, S. B., van der Velden, J. & 1 others, 7 Jan 2019, In : The Journal of general physiology. 151, 1, p. 18-29 12 p.Research output: Contribution to journal › Article › Academic › peer-review
The presence of cerebral white matter lesions and lower skin microvascular perfusion predict lower cognitive performance in type 1 diabetes patients with retinopathy but not in healthy controls - a longitudinal study
Emanuel, A. L., van Duinkerken, E., Wattjes, M. P., Klein, M., Barkhof, F., Snoek, F. J., Diamant, M., Eringa, E. C., IJzerman, R. G. & Serné, E. H., 19 Jan 2019, In : Microcirculation. p. e12530Research output: Contribution to journal › Article › Academic › peer-review
Untying the knot: protein quality control in inherited cardiomyopathies
Dorsch, L. M., Schuldt, M., Knežević, D., Wiersma, M., Kuster, D. W. D., van der Velden, J. & Brundel, B. J. J. M., 1 May 2019, In : Pflugers Archiv European Journal of Physiology. 471, 5, p. 795-806Research output: Contribution to journal › Article › Academic › peer-review
Open Access
2018
Adaptations in muscle oxidative capacity, fiber size, and oxygen supply capacity after repeated-sprint training in hypoxia combined with chronic hypoxic exposure
van der Zwaard, S., Brocherie, F., Kom, B. L. G., Millet, G. P., Deldicque, L., van der Laarse, W. J., Girard, O. & Jaspers, R. T., 2018, In : Journal of Applied Physiology. 124, 6, p. 1403-1412Research output: Contribution to journal › Article › Academic › peer-review
A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
Baardman, J., Verberk, S. G. S., Prange, K. H. M., van Weeghel, M., van der Velden, S., Ryan, D. G., Wüst, R. C. I., Neele, A. E., Speijer, D., Denis, S. W., Witte, M. E., Houtkooper, R. H., O'neill, L. A., Knatko, E. V., Dinkova-Kostova, A. T., Lutgens, E., de Winther, M. P. J. & Van den Bossche, J., 20 Nov 2018, In : Cell Reports. 25, 8, p. 2044-2052.e5Research output: Contribution to journal › Article › Academic › peer-review
Open Access
A functional siRNA screen identifies RhoGTPase-associated genes involved in thrombin-induced endothelial permeability
Amado-Azevedo, J., de Menezes, R. X., van Nieuw Amerongen, G. P., van Hinsbergh, V. W. M. & Hordijk, P. L., 2018, In : PLoS ONE. 13, 7, e0201231.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
A local uPAR-plasmin-TGFβ1 positive feedback loop in a qualitative computational model of angiogenic sprouting explains the in vitro effect of fibrinogen variants
Boas, S. E. M., Carvalho, J., van den Broek, M., Weijers, E. M., Goumans, M-J., Koolwijk, P. & Merks, R. M. H., 2018, In : PLoS Computational Biology. 14, 7, e1006239.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
An in vitro method to keep human aortic tissue sections functionally and structurally intact
Meekel, J. P., Groeneveld, M. E., Bogunovic, N., Keekstra, N., Musters, R. J. P., Zandieh-Doulabi, B., Pals, G., Micha, D., Niessen, H. W. M., Wiersema, A. M., Kievit, J. K., Hoksbergen, A. W. J., Wisselink, W., Blankensteijn, J. D. & Yeung, K. K., 1 Dec 2018, In : Scientific Reports. 8, 1, 8094.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Application of kinomic array analysis to screen for altered kinases in atrial fibrillation remodeling
Meijering, R. A. M., Wiersma, M., Zhang, D., Lanters, E. A. H., Hoogstra-Berends, F., Scholma, J., Diks, S., Qi, X. Y., de Groot, N. M. S., Nattel, S., Henning, R. H. & Brundel, B. J. J. M., 1 Nov 2018, In : Heart Rhythm. 15, 11, p. 1708-1716 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Betaglycan (TGFBR3) up-regulation correlates with increased TGF-β signaling in Marfan patient fibroblasts in vitro
Groeneveld, M. E., Bogunovic, N., Musters, R. J. P., Tangelder, G. J., Pals, G., Wisselink, W., Micha, D. & Yeung, K. K., Jan 2018, In : Cardiovascular Pathology. p. 44-49Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Blood Outgrowth and Proliferation of Endothelial Colony Forming Cells are Related to Markers of Disease Severity in Patients with Pulmonary Arterial Hypertension
Smits, J., Tasev, D., Andersen, S., Szulcek, R., Botros, L., Ringgaard, S., Andersen, A., Vonk-Noordegraaf, A., Koolwijk, P. & Bogaard, H. J., 2018, In : International Journal of Molecular Sciences. 19, 12Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Burst-like transcription of mutant and wildtype MYH7-alleles as possible origin of cell-to-cell contractile imbalance in Hypertrophic Cardiomyopathy
Montag, J., Kowalski, K., Makul, M., Ernstberger, P., Radocaj, A., Beck, J., Becker, E., Tripathi, S., Keyser, B., Mühlfeld, C., Wissel, K., Pich, A., van der Velden, J., dos Remedios, C. G., Perrot, A., Francino, A., Navarro-López, F., Brenner, B. & Kraft, T., 9 Apr 2018, In : Frontiers in Physiology. 9, APR, 359.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Cardiovascular Function of Modern Pigs Does not Comply with Allometric Scaling Laws
Van Essen, G. J., Hekkert, M. T. L., Sorop, O., Heinonen, I., Van Der Velden, J., Merkus, D. & Duncker, D. J., 1 Aug 2018, In : Scientific Reports. 8, 1, 792.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization
Manavski, Y., Lucas, T., Glaser, S. F., Dorsheimer, L., Guenther, S., Braun, T., Rieger, M. A., Zeiher, A. M., Boon, R. A. & Dimmeler, S., 2 Mar 2018, In : Circulation Research. 122, 5, p. 670-677Research output: Contribution to journal › Article › Academic › peer-review
Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension
Da Silva Gonçalves Bós, D., Van Der Bruggen, C. E. E., Kurakula, K., Sun, X. Q., Casali, K. R., Casali, A. G., Rol, N., Szulcek, R., Dos Remedios, C., Guignabert, C., Tu, L., Dorfmüller, P., Humbert, M., Wijnker, P. J. M., Kuster, D. W. D., Van Der Velden, J., Goumans, M. J., Bogaard, H. J., Vonk-Noordegraaf, A., De Man, F. S. & 1 others, 1 Jan 2018, In : Circulation. 137, 9, p. 910-924 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Converse role of class I and class IIa HDACs in the progression of atrial fibrillation
Zhang, D., Hu, X., Li, J., Hoogstra-Berends, F., Zhuang, Q., Esteban, M. A., de Groot, N., Henning, R. H. & Brundel, B. J. J. M., 1 Dec 2018, In : Journal of Molecular and Cellular Cardiology. 125, p. 39-49 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Correction: Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor
Smeets, M. W. J., Bierings, R., Meems, H., Mul, F. P. J., Geerts, D., Vlaar, A. P. J., Voorberg, J. & Hordijk, P. L., 21 Mar 2018, In : PLoS ONE. 13, 3, e0194958.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Critical determinants of combined sprint and endurance performance: an integrative analysis from muscle fiber to the human body
van der Zwaard, S., van der Laarse, W. J., Weide, G., Bloemers, F. W., Hofmijster, M. J., Levels, K., Noordhof, D. A., de Koning, J. J., de Ruiter, C. J. & Jaspers, R. T., 31 Mar 2018, In : FASEB Journal. 32, p. 2110-2123 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy
Brynnel, A., Hernandez, Y., Kiss, B., Lindqvist, J., Adler, M., Kolb, J., van der Pijl, R., Gohlke, J., Strom, J., Smith, J., Ottenheijm, C. & Granzier, H. L., 19 Dec 2018, In : eLife. 7, e40532.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Dysfunctional sarcomere contractility contributes to muscle weakness in ACTA1-related nemaline myopathy (NEM3)
Joureau, B., de Winter, J. M., Conijn, S., Bogaards, S. J. P., Kovacevic, I., Kalganov, A., Persson, M., Lindqvist, J., Stienen, G. J. M., Irving, T. C., Ma, W., Yuen, M., Clarke, N. F., Rassier, D. E., Malfatti, E., Romero, N. B., Beggs, A. H. & Ottenheijm, C. A. C., 1 Feb 2018, In : Annals of Neurology. 83, 2, p. 269-282 14 p.Research output: Contribution to journal › Article › Academic › peer-review