Research Institutes

Research Output 1979 2020

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2007

Chemistry and Biology of Pteridines and Folates

Jansen, G. & Peters, GJ., 2007, Proceedings 13th International Symposium on Chemistry and Biology of Pteridines and Folates. Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 1-607 607 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Effects of polymorphisms in folate-related genes on methotrexate sensitivity and risk of acute lymphoblastic leukemia

de Jonge, R., Tissing, W. J., van Zelst, B. D., Jansen, G., Kaspers, GJL., Peters, GJ., Pieters, R. & Lindemans, J., 2007, In: "Chemistry and Biology of Pteridines and Folates" . Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 515-534 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Hermeneutic Ethics between Practice and Theory

Widdershoven, G. A. M. & Abma, T. A., 18 Jun 2007, Principles of Health Care Ethics: Second Edition. John Wiley and Sons Inc., p. 215-221 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Infectieziekten

Tutu-van Furth, AM. & Haarman, EG., 2007, Infectieziekten. Terra Lannoo

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Meningitis en sepsis

Sie, SD. & Tutu-van Furth, AM., 2007, Meningitis en sepsis. Bohn Stafleu van Loghum

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Prediction of an unfavourable course of low back pain in general practice: Comparison of four instruments

Jellema, P., van der Windt, D. A. W. M., van der Horst, H. E., Stalman, W. A. B. & Bouter, L. M., Jan 2007, British Journal of General Practice. p. 15-22 8 p. (British Journal of General Practice; vol. 57).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Sulfasalazine exposure confers MTX resistance in human monocytic/macrophage cells by differential effects on folate influx and efflux systems

Oerlemans, R., van der Heijden, JW., Dijkmans, BAC., Lems, WF., Scheper, RJ., Assaraf, Y. G. & Jansen, G., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 177-187 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

The interaction between folate homeostasis and MRPs/ABCCs and BCRP/ABCG2 expression: role in cellular drug resistance

Hooijberg, J. H., Lemos, C., Jansen, G., Assaraf, Y. G., Pieters, R., Kaspers, GJL., Priest, D. G., Wielinga, P. & Peters, GJ., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 189-204 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

The involvement of aβ in the neuroinflammatory response

Eikelenboom, P., Van Gool, W. A., Rozemuller, A. J. M., Scheper, W., Veerhuis, R. & Hoozemans, J. J. M., 1 Dec 2007, Abeta Peptide and Alzheimer's Disease: Celebrating a Century of Research. Springer London, p. 52-82 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

TRAIL modulators

Mom, C. H., Sloots, I. A., de Jong, S., Gietema, J. A., de Vries, E. G. E. & Sleijfer, S., 1 Jan 2007, Targeted Therapies in Oncology. CRC Press, p. 207-222 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Vlekjesziekten

Haarman, EG., van Essen, G. A. & Tutu-van Furth, AM., 2007, Vlekjesziekten.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2006

C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates.

van Vliet, SJ., Grün, C. H. & van Kooyk, Y., 2006, Protein-carbohydrate interactions in infectious diseases. p. 106-124

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Depression and physical disability

Penninx, B. W. J. H., 1 Jan 2006, Depression and Physical Illness. Cambridge University Press, p. 125-144 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Neuroblastoma

Van Der Kleij, A. & Sminia, P., 1 Jan 2006, Handbook on Hyperbaric Medicine. Springer Netherlands, p. 469-475 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Pathogen-recognition receptors as targets for pathogens to modulate immune function of antigen presenting cells.

Engering, A., van Vliet, SJ., Koppel, E. A., Geijtenbeek, TBH. & van Kooyk, Y., 2006, Dendritic cell interactions with bacteria. p. 173-192

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Women’s aging and depression

Penninx, B. W. J. H., 1 Jan 2006, Women and Depression: A Handbook for the Social, Behavioral, and Biomedical Sciences. Cambridge University Press, p. 129-144 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2005

Experimental autoimmune encephalomyelitis in Primates

Smith, P. A., Amor, S. & 'Thart, B. A., 1 Jan 2005, Experimental Models of Multiple Sclerosis. Springer US, p. 561-576 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Interpretation and dialogue in hermeneutic ethics

Widdershoven, G., 1 Jan 2005, Case Analysis in Clinical Ethics. Cambridge University Press, p. 57-76 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Philosophical introduction: Case analysis in clinical ethics

Ashcroft, R., Parker, M., Verkerk, M. & Widdershoven, G., 1 Jan 2005, Case Analysis in Clinical Ethics. Cambridge University Press, p. 1-6 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Philosophical reflections

Parker, M., Ashcroft, R., Verkerk, M. & Widdershoven, G., 1 Jan 2005, Case Analysis in Clinical Ethics. Cambridge University Press, p. 225-230 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Summary of the practice guideline 'Miscarriage' (second revision) from the Dutch College of General Practitioners (NHG)

van Balen, J. A. M., Flikweert, S., Wieringa-de Waard, M., de jonge, A., Wiersma, T. & Goudswaard, A. N., 2005, Nederlands Tijdschrift voor Geneeskunde. Netherlands: Bohn Stafleu Van Loghum bv, p. 295-298 4 p. (Nederlands Tijdschrift voor Geneeskunde; vol. 149).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

The Behaviour Change Process

Snoek, F. J. & Rubin, R. R., 8 Jun 2005, Prevention of Type 2 Diabetes. John Wiley & Sons, Ltd, p. 169-177 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Unipolaire stemmingsstoornissen

van Schaik, DJF., Bruijn, J. & Hoogendijk, WJG., 2005, Leerboek Psychiatrie: Unipolaire stemmingsstoornissen. De Tijdstroom, p. 235-257 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

2003

Infectieziekten

Tutu-van Furth, AM. & de Jonge, RCJ., 2003, Infectieziekten.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Meningokokken en pneumokokken infecties: Meningokokken en pneumokokken infecties

Wulffele-de Kleijn, ED. & Tutu-van Furth, AM., 2003, Meningokokken en pneumokokken infecties. Bohn Stafleu van Loghum

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2002

Een kind met een zwelling in de hals

Zwijnenburg, PJG. & Tutu-van Furth, AM., 2002, Een kind met een zwelling in de hals. uitgeverij de Tijdstroom

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2001

Antimetabolites

Peters, GJ. & Jansen, G., 2001, In: "Oxford Textbook of Oncology". Souhami, RL., Tannock, I., Hohenberger, P. & Horiot, JC. (eds.). Oxford University Press, p. 663-713 51 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Coronary MRA techniques without breath-holding. In coronary magnetic resonance angiography

Li, D., Hofman, MBM., Lorenz, C. H. & Haacke, E. M., 2001, In coronary magnetic resonance angiography. Duerinckx, AJ. (ed.). Springer_Verlag

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Kinetics of reduced folate carrier and membrane-associated folate receptor mediated transport of antifolates

Mauritz, R., Peters, GJ., Kathmann, G. A. M., Rosowsky, A., Pinedo, HM. & Jansen, G., 2001, In: "Chemistry and Biology of Pteridines and Folates". Milstein, S., Kapatos, G., Levine, RA. & Shane, B. (eds.). Kluwer Academic Publishers, p. 649-654 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Randomised controlled trial of disclosure of emotionally important events in somatisation in primary

Schilte, A. F., Portegijs, P. J. M., Blankenstein, A. H., van der Horst, H. E., Latour, M. B. F., van Eijk, J. T. M. & Knottnerus, J. A., 14 Jul 2001, BMJ. p. 86-86 1 p. (BMJ; vol. 323).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Role of multidrug resistance proteins (MRP) in resistance to antifolates and folate homeostasis

Jansen, G., Assaraf, Y. G., Priest, D. G., Kool, M., Kathman, I., Hooijberg, J. H., Scheper, RJ., Dijkmans, BAC., Kaspers, GJL. & Peters, GJ., 2001, In: "Chemistry and Biology of Pteridines and Folates". Milstien, S., Kapatos, G., Levine, RA. & Shane, B. (eds.). Kluwer Academic Publishers, p. 643-648 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

2000

Infecties van het centraal zenuwstelsel

Roord, J. J. & Tutu-van Furth, AM., 2000, Therapie Information. Bohn Stafleu van Loghum, Vol. 67. p. 1-71

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Principes van Radiotherapie

Stalpers, L. J. A., Sminia, P. & Slotman, BJ., 2000, Behandeling van Kanker. Veenhof, C. & Voute, P. (eds.). BohnStafleu VanLoghum, p. 10-26 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1999

[Intravenous high-dose methylprednisolone efficacy for treatment of idiopathic thrombocytopenic purpura in adults]

Visser, R., Zweegman, S., Ossenkoppele, G. J. & Huijgens, P. C., 1999, Nederlands Tijdschrift voor Geneeskunde. 1999/11/24 ed. p. 2053-2057 5 p. (Nederlands Tijdschrift voor Geneeskunde; vol. 143).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Receptor- and carrier-mediated transport systems for folates and antifolates: exploitation for folate-based chemotherapy and immunotherapy

Jansen, G., 1999, In: "Antifolate Drugs in Cancer Therapy". Jackman, AL. (ed.). Humana Press, p. 293-321 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

1997

Activity of folylpolyglutamate synthetase and hydrolase in clinical specimens of head and necks tumors

Jansen, G., Kathman, I., Hordijk, G. J., Slootweg, P. J., Peters, GJ. & van der Laan, B. F. A. M., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 459-462 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Altered metabolism of (anti)folates in pyrimethamine resistant Chinese hamster ovary cells

Jansen, G., Barr, HM., Kathman, I., Peters, GJ., Bunni, M. A., Priest, D. G. & Assaraf, Y. G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 253-256 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

A novel mechanism of resistance to polyglutamatable antifolates in human CEM leukemia cells: association with the expression of an altered reduced folate carrier (RFC) with enhanced efficiency for folic acid uptake

Mauritz, R., Kathman, I., Assaraf, Y. G., Drori, S., Priest, D. G., Bunni, M. A., Pinedo, HM., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 157-162 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Mechanisms of methotrexate (MTX) resistance and its circumvention by novel antifolates in childhood leukemia

Rots, M. G., Pieters, R., Veerman, A. J. P., van Zantwijk, C. H., Noordhuis, P., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 175-180 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Mechanisms of resistance against methotrexate and novel antifolates in human CCRF-CEM leukemia cells

Kathmann, I., Mauritz, R., Noordhuis, P., Voorn, D. A., Aardewijn, P., Schornagel, J. H., Pinedo, HM., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 257-261 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Multilayered tumor cell line cultures as in vitro drug screening model for new thymidylate synthase (TS) inhibitors

Smid, K., Smitskamp-Wilms, E., Jansen, G., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 237-240 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Preclinical activity of PT523 in relation to transport

Peters, GJ., Braakhuis, BJM., Rosowsky, A., Kegel, A., Rots, M. G., van der Wilt, C. L., Pinedo, HM. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 267-270 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and resistant leukemia cells

Jansen, G., Assaraf, Y. G., Kathman, I., Mauritz, R., Sprecher, H., Priest, D. G., Bunni, M. A., Schornagel, J. H., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 111-122 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Role of cell culture medium folate levels on growth inhibition by thymidylate synthase inhibitors in squamous cell cancer and colon cancer cells

Backus, H. H. J., Wouters, D., van der Wilt, C. L., Jansen, G., Kuiper, C. M., van Groeningen, C. J., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 299-232 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Role of folylpolyglutamate hydrolase in methotrexate resistance in childhood leukemia

Noordhuis, P., Rots, M. G., van Zantwijk, C. H., Pieters, R., Veerman, A. J. P., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 463-466 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

1996

G-CSF (filgrastim)-stimulated whole blood kept unprocessed at 4 degrees C does support a BEAM-like regimen in bad-risk lymphoma

Ossenkoppele, G. J., Schuurhuis, G. J., Jonkhoff, A. R., Drager, A. M., Westra, G., Oberink, J. W., Legdeur, M. C., de Kreuk, A. M., Zweegman, S. & Huijgens, P. C., 1996, Bone Marrow Transplant. 1996/08/01 ed. p. 427-431 5 p. (Bone Marrow Transplant; vol. 18).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Resistance to antimetabolites

Peters, GJ. & Jansen, G., 1996, In: "Principles of antineoplastic drug development and pharmacology" . Schilsky, RL., Milano, G. & Ratain, MJ. (eds.). Marcel Dekker, Inc, NY, p. 543-584 42 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Sensitivity for novel antifolates in childhood leukemia cells with resistance to methotrexate

Bekkenk, M., Mauritz, R., Pieters, R., Rots, M. G., van Zantwijk, C. H., Veerman, A. J. P., Peters, GJ. & Jansen, G., 1996, In: "Drug resistance in leukemia and lymphoma". Pieters, R., Kaspers, GJL. & Veerman, AJP. (eds.). Harwood Academic Publishers, p. 173-181 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

1995

The impact of transport-associated resistance in anticancer therapy

Broxterman, HJ., Jansen, G., Linn, S. C. & Lankelma, J., 1995, In: "Drug transport in antimicrobial and anticancer chemotherapy". Georgopapadakou, NH. (ed.). Marcel Dekker, Inc, NY, p. 21-62 42 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional