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The coarse-grained A beta plaque; a 'new' kid on the block in early-onset Alzheimer's disease, showing a strong association with both inflammatory and vascular changes

Boon, B. D. C., Bulk, M., Jonker, A. J., Morrema, T. H. J., van den Berg, E., Popovic, M., Walter, J., Kumar, S., Natte, R., van der Weerd, L., Bouwman, F. H., van de Berg, W. D. J., Hoozemans, J. J. M. & Rozemuller, A. J. M., Mar 2020, In : Neuropathology and Applied Neurobiology. 46, p. 39-40

Research output: Contribution to journalMeeting AbstractAcademic

2019

78. Machine Learning Classification of Obsessive-Compulsive Disorder Using Structural Neuroimaging Data: ENIGMA Working Group

Bruin, W., Shock, J., Thomas, R., Groenewold, N., Boedhoe, P., Thompson, P. M., van den Heuvel, O., Stein, D. J. & van Wingen, G., May 2019, In : Biological Psychiatry. 85, 10, p. S32

Research output: Contribution to journalMeeting AbstractAcademic

79. Association Between Illness Duration and Psychotropic Medication in Obsessive-Compulsive Disorder and Altered Brain Structural Covariance Networks: A Multi-Center Analysis

Yun, J-Y., Boedhoe, P. S. W., Jahanshad, N., Thompson, P. M., Stein, D. J., van den Heuvel, O. & Kwon, J. S., May 2019, In : Biological Psychiatry. 85, 10, p. S33

Research output: Contribution to journalMeeting AbstractAcademic

80. Subcortical Brain Volume, Regional Cortical Thickness and Surface Area Alterations Across ADHD, ASD, and OCD

Boedhoe, P., van Rooij, D., Hoogman, M., Schmaal, L., Thompson, P. M., Stein, D. J., Buitelaar, J., Franke, B. & van den Heuvel, O., May 2019, In : Biological Psychiatry. 85, 10, p. S33

Research output: Contribution to journalMeeting AbstractAcademic

Anti-IL-6 Treatment Ameliorates the Pulmonary Hypertension Phenotype in Tnfaip3(DNGR1-KO)Mice

Koudstaal, T., van Hulst, J. A., Heukels, P., Merkus, D., de Raaf, M. A., Bergen, I. M., Bogaard, H. J., Boon, L., van Loo, G., Aerts, J. G., Hendriks, R. W., Boomars, K. A. & Kool, M., 2019, In : American Journal of Respiratory and Critical Care Medicine. 199

Research output: Contribution to journalMeeting AbstractAcademic

Association between ventral subthalamic deep brain stimulation and apathy in Parkinson’s disease

Figee, M., Zoon, T., Boon, L., Potters, W., van Rootselaar, F. & de Bie, R., 22 Jan 2019, In : Brain stimulation. 12, 2, p. 522

Research output: Contribution to journalMeeting AbstractAcademic

A TAILOR-MADE EXERCISE PROGRAM DESIGNED FOR IMPROVING CARDIORESPIRATORY FITNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS AND INCREASED CARDIOVASCULAR RISK

van den Hoek, J., van der Esch, M., van der Leeden, M., Lems, W., Metsios, G., Kitas, G. D., Dekker, J., Reimer, W. S. O., Jorstad, H., L'ami, M. J., Heslinga, M. & Nurmohamed, M., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1061-1061

Research output: Contribution to journalMeeting AbstractAcademic

Axonal degeneration as substrate of fractional anisotropy abnormalities in Multiple sclerosis cortex

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., Van de Berg, W. D., Schenk, G., Rocca, M. A., Filippi, M., Geurts, J. & Jonkman, L. E., Jul 2019, In : European Journal of Neurology. 26, p. 107-107

Research output: Contribution to journalMeeting AbstractAcademic

Bosutinib Protects against Vascular Leakage by Improving Endothelial Cell-Matrix Adhesion

Botros, L., Pronk, M., Juschten, J., Liddle, J., Tuinman, P. R., van Bezu, J., Huveneers, S., Bogaard, H. J., van Hinsbergh, V., Hordijk, P. & Aman, J., 2019, In : Journal of Vascular Research. 56, p. 15-15

Research output: Contribution to journalMeeting AbstractAcademic

Characterization of brainstem TDP-43 distribution in FTD cases with ALS features

Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436

Research output: Contribution to journalMeeting AbstractAcademic

COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART-BRAIN AXIS: THE ROLE OF CEREBRAL BLOOD FLOW

Leeuwis, A. E., Hooghiemstra, A. M., Bron, E. E., Kuipers, S., Oudeman, E. A., Kalay, T., Brunner-La Rocca, H-P. H. P., Kappelle, J., van Oostenbrugge, R. J., Greving, J. P., Niessen, W. J., van Buchem, M. A., van Osch, M. J. P., van Rossum, A., Prins, N. D., Biessels, G. J., Barkhof, F. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P755-P756

Research output: Contribution to journalMeeting AbstractAcademic

Cognitive rehabilitation in patients with advanced progressive multiple sclerosis: possible within limits?

Prouskas, S. E., Chiaravalloti, N. D., Kant, N., Ball, K. K., de Groot, V., Uitdehaag, B. M. J., Geurts, J. J. G., Kooij, E. A. & Hulst, H. E., 10 Sep 2019, (Submitted) In : Multiple Sclerosis Journal. 228.

Research output: Contribution to journalMeeting AbstractAcademic

COGNITIVE SEQUELAE OF RADIOTHERAPY IN LOW-GRADE GLIOMA PATIENTS 26 YEARS AFTER INITIAL DIAGNOSIS: FINAL REPORT

den Otter, P. W. M., Lorenz, L. M. C., Reijneveld, J. C., Hamer, P. C. D. W., Taphoorn, M., Kouwenhoven, M. C. M., Snijders, T., Lie, S. T., Douw, L. & Klein, M., Nov 2019, In : Neuro-Oncology. 21, p. 160-160

Research output: Contribution to journalMeeting AbstractAcademic

COMORBID AMYLOID-β PATHOLOGY AFFECTS NEUROPSYCHIATRIC, NEUROPSYCHOLOGICAL, AND IMAGING FEATURES IN VASCULAR COGNITIVE DISORDERS

Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P888-P889

Research output: Contribution to journalMeeting AbstractAcademic

Consensus building at the Second International Stroke Recovery and Rehabilitation Roundtable

Bernhardt, J., Borschmann, K., Kwakkel, G., Burridge, J., Eng, J., Walker, M., Bird, M-L., Cramer, S., Hayward, K., O'Sullivan, M., Clarkson, A. & Corbett, D., Sep 2019, In : International Journal of Stroke. 14, p. 12-12

Research output: Contribution to journalMeeting AbstractAcademic

COPY-NUMBER SIGNATURES AND MUTATIONAL PROCESSES IN HIGH GRADE SEROUS OVARIAN CARCINOMA

Macintyre, G., Goranova, T. E., De Silva, D., Ennis, D., Piskorz, A. M., Eldridge, M., Sie, D., Lewsley, L-A., Hanif, A., Wilson, C., Dowson, S., Glasspool, R. M., Lockley, M., Brockbank, E., Montes, A., Walther, A., Sundar, S., Edmondson, R., Hall, G. D., Clamp, A. & 19 others, Gourley, C., Hall, M., Fotopoulou, C., Gabra, H., Paul, J., Supernat, A., Millan, D., Hoyle, A., Bryson, G., Nourse, C., Mincarelli, L., Sanchez, L. N., Ylstra, B., Jimenez-Linan, M., Moore, L., Hofmann, O., Markowetz, F., McNeish, I. A. & Brenton, J. D., Nov 2019, In : Clinical Cancer Research. 25, 22, p. 64-64

Research output: Contribution to journalMeeting AbstractAcademic

Default-mode network dysfunction can predict cognitive decline in multiple sclerosis

Huiskamp, M., Pasteuning, J., Eijlers, A. J. C., Prouskas, S. E., Broeders, T. A. A., Uitdehaag, B. M. J., Hulst, H. E., Wink, A. M., Geurts, J. J. G. & Schoonheim, M. M., 4 Oct 2019, (In preparation) In : Multiple Sclerosis Journal.

Research output: Contribution to journalMeeting AbstractAcademic

Delayed arrival of arterial blood in cortex is associated with decreased CSF levels of amyloid beta in predementia Alzheimer's disease

Palhaugen, L., Selnes, P., Tecelao, S., Lysvik, E. K., Ingala, S., Petr, J., Bjornerud, A., Mutsaerts, H. J. & Fladby, T., Jul 2019, In : European Journal of Neurology. 26, p. 358-358

Research output: Contribution to journalMeeting AbstractAcademic

Demyelination, Inflammation and Axonal Loss Explain Different Patterns of Fractional Anisotropy Abnormalities in MS Cortical Normal Appearing Gray Matter and Lesions

Preziosa, P., Kiljan, S., Steenwijk, M. D., Meani, A., van de Berg, W., Schenk, G., Rocca, M., Filippi, M., Geurts, J. J. G. & Jonkman, L., 9 Apr 2019, In : Neurology. 92, 15

Research output: Contribution to journalMeeting AbstractAcademic

DEVELOPMENT AND TESTING OF A SMARTPHONE APPLICATION TO SELF-MONITOR DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS

Seppen, B., L'ami, M. J., Rico, S., Ter Wee, M., Turkstra, F., Roorda, L. D., Catarinella, F., van Schaardenburg, D., Nurmohamed, M., Boers, M. & Bos, W. H., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1384-1384

Research output: Contribution to journalMeeting AbstractAcademic

DEVELOPMENT AND USABILITY OF ADAPPT: AN ONLINE TOOL TO SUPPORT CLINICIANS, PATIENTS AND CAREGIVERS IN THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT AND ALZHEIMER’S DISEASE

Van Maurik, I. S., Visser, L. N. C., Pel-Littel, R., van Buchem, M., Zwan, M. D., Kunneman, M., Pelkmans, W., Bouwman, F. H., Minkman, M., Schoonenboom, N. S. M., Scheltens, P., Smets, E. M. & van der Flier, W. M., Jul 2019, In : Alzheimers & Dementia. 15, 7, p. P163-P164

Research output: Contribution to journalMeeting AbstractAcademic

Development of prescribing knowledge and skills of junior doctors in the first year after graduation

Donker, E., Brinkman, D., van den Brink, A. M., Janssen, B., Knol, W., Dumont, G., Jorens, P., Dupont, A., Christiaens, T., Smeden, J., De Waard-Siebinga, I., Peeters, L., Goorden, R., Hessel, M., Richir, M., Van Agtmael, M., Kramers, K. & Tichelaar, J., Jun 2019, In : European Journal of Clinical Pharmacology. 75, p. S58-S58

Research output: Contribution to journalMeeting AbstractAcademic

Diagnostic yield of NGS analysis of a panel of Osteogenesis imperfecta-related genes in 550 patients with Osteogenesis imperfecta, (early-onset) nonsyndromic osteoporosis and related disorders

Maugeri, A., Voorhoeve, E., Appelman-Dijkstra, N. M., van Dijk, A. T. H., van Dijk, F. S., Eekhoff, E. M. W., Elting, M. W., van Haeringen, A., Harsevoort, A., Isrie, M., Janus, G. J. M., de Jongh, R. T., van de Kamp, J. M., van Maarle, M. C., Marcelis, C. L. M., Simon, M. E. H., Simsek, S., Stumpel, C. T. R. M., Terhal, P. A., Veenstra-Knol, H. E. & 6 others, Zillikens, M. C., Meijers-Heijboer, E. J., Sistermans, E. A., Weiss, M. M., Pals, G. & Micha, D., Oct 2019, In : European Journal of Human Genetics. 27, p. 1293-1293

Research output: Contribution to journalMeeting AbstractAcademic

Dose-escalation study of G1T48, an oral selective estrogen receptor degrader (SERD), in postmenopausal women with ER+/HER2- locally advanced or metastatic breast cancer (ABC)

Dees, E. C., Aftimos, P. G., Menke, C. W., De Vries, E. G. E., Neven, P., Pegram, M. D., Iqbal, R., Boers, J., Xiao, J., Sipes, C., Li, C., Sorrentino, J. A., Malik, R. & Beelen, A. P., 1 Oct 2019, In : Annals of Oncology. 30, Supplement 5

Research output: Contribution to journalMeeting AbstractAcademic

Open Access

Downregulation of Tie2 Induces Microvascular Leakage in Mice

van Leeuwen, A. L. I., Dekker, N. A. M., van Meurs, M., Molema, I. & van den Brom, C. E., 2019, In : Journal of Vascular Research. 56, p. 118-118

Research output: Contribution to journalMeeting AbstractAcademic

Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder

Thorsen, A. L., Vriend, C., de Wit, S., Ousdal, O., Hagen, K., Hansen, B., Kvale, G. & van den Heuvel, O., 15 May 2019, In : Biological Psychiatry. 85, 10, p. S300-S300

Research output: Contribution to journalMeeting AbstractAcademic

Establishing clinical thresholds of multi-item tests: an item response theory approach to cut-off scores

Terluin, B., Griffiths, P., van der Wouden, J., Ingelsrud, L. H. & Terwee, C., Oct 2019, In : Quality of Life Research. 28, p. S88-S88

Research output: Contribution to journalMeeting AbstractAcademic

Extending the Proportional Recovery Rule of the Upper Paretic Limb Early After Stroke

van der Vliet, R., Selles, R., Andrinopoulou, E-R., Nijland, R., Frens, M., Meskers, C., Ribbers, G. & Kwakkel, G., 2 May 2019, In : Brain Injury. 33, p. 310-310

Research output: Contribution to journalMeeting AbstractAcademic

Factors influencing Autonomy Supportive consultation: a realist review

Kors, JM., Paternotte, E., Martin, L., Verhoeven, C., Schoonmade, L. J., Peerdeman, SM. & Kusurkar, RA., 15 Jan 2019, (Accepted/In press) In : conference abstracts.

Research output: Contribution to journalMeeting AbstractAcademic

FEASIBILITY OF A FIRST PEDIATRIC METABOLITE IN SAFETY TESTING PILOT STUDY USING AN ORAL C-14-MIDAZOLAM MICROTRACER.

van Groen, B. D., van Duijn, E., de Vries, A., Mooij, M. G., Windhorst, A. D., Hendrikse, N. H., Tibboel, D., Vaes, W. H. J. & de Wildt, S. N., Mar 2019, In : Clinical Pharmacology & Therapeutics. 105, p. S38-S38

Research output: Contribution to journalMeeting AbstractAcademic