Research Institutes

Research Output 1979 2020

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Meeting Abstract

Anti-IL-6 Treatment Ameliorates the Pulmonary Hypertension Phenotype in Tnfaip3(DNGR1-KO)Mice

Koudstaal, T., van Hulst, J. A., Heukels, P., Merkus, D., de Raaf, M. A., Bergen, I. M., Bogaard, H. J., Boon, L., van Loo, G., Aerts, J. G., Hendriks, R. W., Boomars, K. A. & Kool, M., 2019, In : American Journal of Respiratory and Critical Care Medicine. 199

Research output: Contribution to journalMeeting AbstractAcademic

A TAILOR-MADE EXERCISE PROGRAM DESIGNED FOR IMPROVING CARDIORESPIRATORY FITNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS AND INCREASED CARDIOVASCULAR RISK

van den Hoek, J., van der Esch, M., van der Leeden, M., Lems, W., Metsios, G., Kitas, G. D., Dekker, J., Reimer, W. S. O., Jorstad, H., L'ami, M. J., Heslinga, M. & Nurmohamed, M., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1061-1061

Research output: Contribution to journalMeeting AbstractAcademic

Bosutinib Protects against Vascular Leakage by Improving Endothelial Cell-Matrix Adhesion

Botros, L., Pronk, M., Juschten, J., Liddle, J., Tuinman, P. R., van Bezu, J., Huveneers, S., Bogaard, H. J., van Hinsbergh, V., Hordijk, P. & Aman, J., 2019, In : Journal of Vascular Research. 56, p. 15-15

Research output: Contribution to journalMeeting AbstractAcademic

Characterization of brainstem TDP-43 distribution in FTD cases with ALS features

Scarioni, M., Gami-Patel, P., Timar, Y. S., Rozemuller, A. J., Hoozemans, J. J., Aronica, E., Raaphorst, J., Pijnenburg, Y. A. & Dijkstra, A. A., Jul 2019, In : European Journal of Neurology. 26, p. 436-436

Research output: Contribution to journalMeeting AbstractAcademic

Cognitive rehabilitation in patients with advanced progressive multiple sclerosis: possible within limits?

Prouskas, S. E., Chiaravalloti, N. D., Kant, N., Ball, K. K., de Groot, V., Uitdehaag, B. M. J., Geurts, J. J. G., Kooij, E. A. & Hulst, H. E., 10 Sep 2019, (Submitted) In : Multiple Sclerosis Journal. 228.

Research output: Contribution to journalMeeting AbstractAcademic

Default-mode network dysfunction can predict cognitive decline in multiple sclerosis

Huiskamp, M., Pasteuning, J., Eijlers, A. J. C., Prouskas, S. E., Broeders, T. A. A., Uitdehaag, B. M. J., Hulst, H. E., Wink, A. M., Geurts, J. J. G. & Schoonheim, M. M., 4 Oct 2019, (In preparation) In : Multiple Sclerosis Journal.

Research output: Contribution to journalMeeting AbstractAcademic

Delayed arrival of arterial blood in cortex is associated with decreased CSF levels of amyloid beta in predementia Alzheimer's disease

Palhaugen, L., Selnes, P., Tecelao, S., Lysvik, E. K., Ingala, S., Petr, J., Bjornerud, A., Mutsaerts, H. J. & Fladby, T., Jul 2019, In : European Journal of Neurology. 26, p. 358-358

Research output: Contribution to journalMeeting AbstractAcademic

DEVELOPMENT AND TESTING OF A SMARTPHONE APPLICATION TO SELF-MONITOR DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS

Seppen, B., L'ami, M. J., Rico, S., Ter Wee, M., Turkstra, F., Roorda, L. D., Catarinella, F., van Schaardenburg, D., Nurmohamed, M., Boers, M. & Bos, W. H., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1384-1384

Research output: Contribution to journalMeeting AbstractAcademic

Development of prescribing knowledge and skills of junior doctors in the first year after graduation

Donker, E., Brinkman, D., van den Brink, A. M., Janssen, B., Knol, W., Dumont, G., Jorens, P., Dupont, A., Christiaens, T., Smeden, J., De Waard-Siebinga, I., Peeters, L., Goorden, R., Hessel, M., Richir, M., Van Agtmael, M., Kramers, K. & Tichelaar, J., Jun 2019, In : European Journal of Clinical Pharmacology. 75, p. S58-S58

Research output: Contribution to journalMeeting AbstractAcademic

Dose-escalation study of G1T48, an oral selective estrogen receptor degrader (SERD), in postmenopausal women with ER+/HER2- locally advanced or metastatic breast cancer (ABC)

Dees, E. C., Aftimos, P. G., Menke, C. W., De Vries, E. G. E., Neven, P., Pegram, M. D., Iqbal, R., Boers, J., Xiao, J., Sipes, C., Li, C., Sorrentino, J. A., Malik, R. & Beelen, A. P., 1 Oct 2019, In : Annals of Oncology. 30, Supplement 5

Research output: Contribution to journalMeeting AbstractAcademic

Open Access

Downregulation of Tie2 Induces Microvascular Leakage in Mice

van Leeuwen, A. L. I., Dekker, N. A. M., van Meurs, M., Molema, I. & van den Brom, C. E., 2019, In : Journal of Vascular Research. 56, p. 118-118

Research output: Contribution to journalMeeting AbstractAcademic

Establishing clinical thresholds of multi-item tests: an item response theory approach to cut-off scores

Terluin, B., Griffiths, P., van der Wouden, J., Ingelsrud, L. H. & Terwee, C., Oct 2019, In : Quality of Life Research. 28, p. S88-S88

Research output: Contribution to journalMeeting AbstractAcademic

Extending the Proportional Recovery Rule of the Upper Paretic Limb Early After Stroke

van der Vliet, R., Selles, R., Andrinopoulou, E-R., Nijland, R., Frens, M., Meskers, C., Ribbers, G. & Kwakkel, G., 2 May 2019, In : Brain Injury. 33, p. 310-310

Research output: Contribution to journalMeeting AbstractAcademic

Factors influencing Autonomy Supportive consultation: a realist review

Kors, JM., Paternotte, E., Martin, L., Verhoeven, C., Schoonmade, L. J., Peerdeman, SM. & Kusurkar, RA., 15 Jan 2019, (Accepted/In press) In : conference abstracts.

Research output: Contribution to journalMeeting AbstractAcademic

FEASIBILITY OF A FIRST PEDIATRIC METABOLITE IN SAFETY TESTING PILOT STUDY USING AN ORAL C-14-MIDAZOLAM MICROTRACER.

van Groen, B. D., van Duijn, E., de Vries, A., Mooij, M. G., Windhorst, A. D., Hendrikse, N. H., Tibboel, D., Vaes, W. H. J. & de Wildt, S. N., Mar 2019, In : Clinical Pharmacology & Therapeutics. 105, p. S38-S38

Research output: Contribution to journalMeeting AbstractAcademic

Geometric efficacy of breath-hold gated MR-guided SABR for adrenal metastases

de Koste, J. V. S., Palacios, M., Bruynzeel, A., Spoelstra, F., Slotman, B., Lagerwaard, F. & Senan, S., Apr 2019, In : Radiotherapy and Oncology. 133, p. S212-S213

Research output: Contribution to journalMeeting AbstractAcademic

Implementing NIPT as part of a national prenatal screening program: The Dutch TRIDENT studies

Weiss, M. M., Galjaard, R. H., Sistermans, E. A., Bax, C. J., Bekker, M. N., de Die-Smulders, C. E. M., Feenstra, I., Hoffer, M. J. V., den Hollander, N. S., Knapen, M. F. C. M., van Langen, I. M., Lichtenbelt, K. D., Lombardi, P. M., van Maarle, M. C., van der Meij, K. R. M., Pieters, M. J., Schuring-Blom, G. H., Sikkel, E., Stevens, S. J., Suijkerbuijk, R. F. & 4 othersvan der Ven, A. J. E. M., Van Opstal, D., Henneman, L. & Macville, M. V., Jul 2019, In : European Journal of Human Genetics. 27, p. 823-824

Research output: Contribution to journalMeeting AbstractAcademic

Implementing pharmacogenetics by repurposing next generation sequencing data on a personalized card

Santcroos, M. A., Vis, J. K., van der Lee, M., Anvar, S. Y., Kriek, M., Grandia, L., Sie, D. L. S., Cornel, M. C., Bet, P. M. & Swen, J. J., Oct 2019, In : European Journal of Human Genetics. 27, p. 1681-1681

Research output: Contribution to journalMeeting AbstractAcademic

Informing relatives at risk of inherited cardiac conditions: attitudes of healthcare professionals, probands and relatives

Van den Heuvel, L. M., Huisinga, M. J., Hoedemaekers, Y. M., Baas, A. B., Plantinga, M., Henneman, L., van Tintelen, J. P., Smets, E. M. A. & Christiaans, I., Jul 2019, In : European Journal of Human Genetics. 27, p. 674-675

Research output: Contribution to journalMeeting AbstractAcademic

Live birth rate is higher in primary subfertile women undergoing ICSI with high normal compared to low normal range TSH levels

Delprat, C., Van Dam, E., Van de Ven, P., Aissa, K., Ter Haar, M., Feenstra, Y., De Roos, A., Beelen, G., Schats, R. & Lambalk, C., Jul 2019, In : Human Reproduction. 34, p. 402-403

Research output: Contribution to journalMeeting AbstractAcademic

Medical costs of children admitted to the Neonatal Intensive Care Unit; the role and possible value of rapid Whole Exome Sequencing

Keizer, R. A. C. M. O., Deden, A. C., van Zelst-Stams, W. A. G., de Boode, W. P., Henneman, L., van Amstel, J. K. P., Vissers, L. E. L. M. & Frederix, G. W. J., Oct 2019, In : European Journal of Human Genetics. 27, p. 1652-1652

Research output: Contribution to journalMeeting AbstractAcademic

Medication appropriateness for elderly nursing home residents with a limited remaining life expectancy: Adjusting the START/STOPP criteria by means of a Delphi consensus study

Pouw, C. A. M., Smalbrugge, M., Hertogh, P. C. P. M., van Marum, R. J. & Hugtenburg, J. G., Apr 2019, In : International Journal of Clinical Pharmacy. 41, 2, p. 603-603

Research output: Contribution to journalMeeting AbstractAcademic

Methylome-wide association studies for Major Depressive Disorder in blood overlap with methylation results from brain and large-scale GWAS

Aberg, K., Dean, B., Shabalin, A., Zhao, M., Chan, R., Hattab, M., van Grootheest, G., Han, L., Aghajani, M., Milaneschi, Y., Jansen, R., Xie, L., Clark, S., Penninx, B. & van den Oord, E., 2019, In : European Neuropsychopharmacology. 29, p. S807-S808

Research output: Contribution to journalMeeting AbstractAcademic

Molecular genetic, host-derived and clinical determinants of long-term survival in glioblastoma: First results from the ETERNITY study (EORTC 1419).

Weller, M., Reifenberger, G., Le Rhun, E., Clarke, J. L., Soffietti, R., Wick, A., Chinot, O. L., Ducray, F., Hau, P., McDonald, K. L., Marosi, C., Schnell, O., Hottinger, A. F., Reijneveld, J. C., Lombardi, G., Wen, P. Y., Klein, M., Gorlia, T., Felsberg, J. & Hertler, C., 20 May 2019, In : Journal of Clinical Oncology. 37, 15

Research output: Contribution to journalMeeting AbstractAcademic

MR-guided adaptive radiotherapy for intra-abdominal lymphoma

Spoelstra, F., Cobussen, P., Palacios, M., Bruynzeel, A., Lagerwaard, F., Slotman, B. & Senan, S., Apr 2019, In : Radiotherapy and Oncology. 133, p. S30-S31

Research output: Contribution to journalMeeting AbstractAcademic

Neuromuscular Electrical Stimulation Applied to the Abdominal Muscles to Assist Ventilator Weaning in Critically Ill Patients: An Assessor Blinded, Randomized, Sham-Controlled Pilot Study

Mclachlan, A. J., McCaughey, E., Jonkman, A., Boswell-Ruys, C., McBain, R., Bye, E., Hudson, A., Gandevia, S. C., Collins, D., Heunks, L. M. A. & Butler, J., 2019, In : American Journal of Respiratory and Critical Care Medicine. 199

Research output: Contribution to journalMeeting AbstractAcademic

Next Generation Sequencing in health care and clinical research: attuning all steps

Rigter, T., Belien, J. A. M., de Wert, G. M. W. R., Ploem, C., Bunnik, E. M., Bredenoord, A. L. & Cornel, M. C., Oct 2019, In : European Journal of Human Genetics. 27, p. 1790-1791

Research output: Contribution to journalMeeting AbstractAcademic

OS7.5 Healthcare utilization, medication use, and productivity loss in glioma patients with depressive symptoms and their family caregivers

Boele, F. W., Jansen, F., Meads, D., Verdonck-de Leeuw, I. M., Heimans, J. J., Reijneveld, J. C., Short, S. C. & Klein, M., Aug 2019, In : Neuro-Oncology. 21, Supplement_3, p. 15-15

Research output: Contribution to journalMeeting AbstractAcademic