Research Output 1981 2020

2020

A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn’s disease

González-Serna, D., Ochoa, E., López-Isac, E., Julià, A., Degenhardt, F., Ortego-Centeno, N., Radstake, T. R. D. J., Franke, A., Marsal, S., Mayes, M. D., Martín, J., Márquez, A., Assassi, S., Zhou, X., Tan, F. K., Arnett, F. C., Reveille, J. D., Gorlova, O., Chen, W. V., Ying, J. & 69 othersGregersen, P. K., Lee, A. T., Voskuyl, A. E., de Vries-Bouwstra, J., Magro-Checa, C., Broen, J., Koeleman, B. P. C., Simeón, C. P., Fonollosa, V., Guillén, A., Carreira, P., Castellví, I., González-Gay, M. A., Ríos, R., Callejas-Rubio, J. L., Vargas-Hitos, J. A., García-Portales, R., Camps, M. T., Fernández-Nebro, A., González-Escribano, M. F., García-Hernández, F. J., Castillo, M. J., Aguirre, M. Á., Gómez-Gracia, I., Rodríguez-Rodríguez, L., Fernández-Gutiérrez, B., de la Peña, P. G., Vicente, E., Andreu, J. L., Fernández de Castro, M., López-Longo, F. J., Martínez, L., Espinosa, G., Tolosa, C., Pros, A., Rodríguez-Carballeira, M., Narváez, F. J., Rubio-Rivas, M., Ortiz-Santamaría, V., Madroñero, A. B., Díaz, B., Trapiella, L., Sousa, A., Egurbide, M. V., Fanlo-Mateo, P., Sáez-Comet, L., Díaz-González, F., Hernández, V., Beltrán, E., Román-Ivorra, J. A., Grau, E., Alegre-Sancho, J. J., Blanco-García, F. J., Oreiro, N., Freire, M., Balsa, A., Ortiz, A. M., Hunzelmann, N., Riemekasten, G., Distler, J. H. W., Witte, T., Airó, P., Beretta, L., Santaniello, A., Bellocchi, C., Lunardi, C., Moroncini, G., Gabrielli, A. & Scleroderma Genetic Consortium, 1 Dec 2020, In : Scientific Reports. 10, 1, 1862.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Efficacy and safety of denosumab vs. bisphosphonates in postmenopausal women previously treated with oral bisphosphonates

Miller, P. D., Pannacciulli, N., Malouf-Sierra, J., Singer, A., Czerwiński, E., Bone, H. G., Wang, C., Huang, S., Chines, A., Lems, W. & Brown, J. P., 1 Jan 2020, In : Osteoporosis International. 31, 1, p. 181-191

Research output: Contribution to journalArticleAcademicpeer-review

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

Smolen, J. S., Landewé, R. B. M., Bijlsma, J. W. J., Burmester, G. R., Dougados, M., Kerschbaumer, A., McInnes, I. B., Sepriano, A., Van Vollenhoven, R. F., De Wit, M., Aletaha, D., Aringer, M., Askling, J., Balsa, A., Boers, M., Den Broeder, A. A., Buch, M. H., Buttgereit, F., Caporali, R., Cardiel, M. H. & 27 othersDe Cock, D., Codreanu, C., Cutolo, M., Edwards, C. J., Van Eijk-Hustings, Y., Emery, P., Finckh, A., Gossec, L., Gottenberg, J. E., Hetland, M. L., Huizinga, T. W. J., Koloumas, M., Li, Z., Mariette, X., Müller-Ladner, U., Mysler, E. F., Da Silva, J. A. P., Poór, G., Pope, J. E., Rubbert-Roth, A., Ruyssen-Witrand, A., Saag, K. G., Strangfeld, A., Takeuchi, T., Voshaar, M., Westhovens, R. & Van Der Heijde, D., 1 Jan 2020, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

First in man study of [18F]fluoro-PEG-folate PET: a novel macrophage imaging technique to visualize rheumatoid arthritis

Verweij, N. J. F., Yaqub, M., Bruijnen, S. T. G., Pieplenbosch, S., ter Wee, M. M., Jansen, G., Chen, Q., Low, P. S., Windhorst, A. D., Lammertsma, A. A., Hoekstra, O. S., Voskuyl, A. E. & van der Laken, C. J., 23 Jan 2020, In : Scientific Reports. 10, 1, 1047.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Predictors of fatal and non-fatal cardiovascular events in ANCA-associated vasculitis: Data from the Toronto CanVasc cohort

Houben, E., Mendel, A., Carette, S., Voskuyl, A. E., Penne, E. L. & Pagnoux, C., 1 Jan 2020, In : Joint Bone Spine.

Research output: Contribution to journalArticleAcademicpeer-review

Treat-to-target in systemic lupus erythematosus: Where are we?

Ríos-Garcés, R., Espinosa, G., van Vollenhoven, R. & Cervera, R., 1 Jan 2020, In : European Journal of Internal Medicine.

Research output: Contribution to journalReview articleAcademicpeer-review

2019

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus

Fanouriakis, A., Kostopoulou, M., Alunno, A., Aringer, M., Bajema, I., Boletis, J. N., Cervera, R., Doria, A., Gordon, C., Govoni, M., Houssiau, F., Jayne, D., Kouloumas, M., Kuhn, A., Larsen, J. L., Lerstrøm, K., Moroni, G., Mosca, M., Schneider, M., Smolen, J. S. & 8 othersSvenungsson, E., Tesar, V., Tincani, A., Troldborg, A., van Vollenhoven, R., Wenzel, J. R., Bertsias, G. & Boumpas, D. T., 1 Jun 2019, In : Annals of the Rheumatic Diseases. 78, 6, p. 736-745 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

9 Incidence and determinants of vertebral and peripheral fractures in patients with systemic lupus erythematosus: a prospective longitudinal cohort study

Hadiyen, F. E., Tsang-A-Sjoe, M. WP., Wee, M. M. T., Voskuyl, A. E., Lem, W. F. & Bultink, I. EM., Apr 2019.

Research output: Contribution to conferencePaperAcademic

Achieving remission in psoriatic arthritis by early initiation of TNF inhibition: A double-blind, randomised, placebo-controlled trial of golimumab plus methotrexate versus placebo plus methotrexate

van Mens, L. J. J., de Jong, H. M., Fluri, I., Nurmohamed, M. T., van de Sande, M. G. H., Kok, M., van Kuijk, A. W. R. & Baeten, D., 1 May 2019, In : Annals of the Rheumatic Diseases. 78, 5, p. 610-616

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Adaptive trial designs in rheumatology: Report from the OMERACT special interest group

Pickles, T., Alten, R., Boers, M., Bykerk, V., Christensen, J., Christensen, R., van Hoogstraten, H., Simon, L. S., Tam, L-S. & Choy, E. H., Oct 2019, In : Journal of Rheumatology. 46, 10, p. 1406-1408 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

An add-on training program involving breathing exercises, cold exposure, and meditation attenuates inflammation and disease activity in axial spondyloarthritis – A proof of concept trial

Buijze, G. A., de Jong, H. M. Y., Kox, M., van de Sande, M. G., van Schaardenburg, D., van Vugt, R. M., Popa, C. D., Pickkers, P. & Baeten, D. L. P., 1 Jan 2019, In : PLoS ONE. 14, 12, e0225749.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
18 Downloads (Pure)

A Novel Method to Combine Assessment of Benefit and Harm: Outcome Measures in Rheumatology 3×3 Methodology Applied to Two Active Comparator Trials

Boers, M., Singh, J. A., Cofield, S. S., Bridges, S. L., Moreland, L. W., O'Dell, J. R., Wu, H., Leatherman, S. & Curtis, J. R., 1 Feb 2019, In : Arthritis Care and Research. 71, 2, p. 319-322 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39

Spiliopoulou, A., Colombo, M., Plant, D., Nair, N., Cui, J., Coenen, M. J. H., Ikari, K., Yamanaka, H., Saevarsdottir, S., Padyukov, L., Bridges, S. L., Kimberly, R. P., Okada, Y., van Riel, P. L. C. M., Wolbink, G., van der Horst-Bruinsma, I. E., de Vries, N., Tak, P. P., Ohmura, K., Canhão, H. & 12 othersGuchelaar, H-J., Huizinga, T. W. J., Criswell, L. A., Raychaudhuri, S., Weinblatt, M. E., Wilson, A. G., Mariette, X., Isaacs, J. D., Morgan, A. W., Pitzalis, C., Barton, A. & McKeigue, P., 1 Aug 2019, In : Annals of the Rheumatic Diseases. 78, 8, p. 1055-1061 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A TAILOR-MADE EXERCISE PROGRAM DESIGNED FOR IMPROVING CARDIORESPIRATORY FITNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS AND INCREASED CARDIOVASCULAR RISK

van den Hoek, J., van der Esch, M., van der Leeden, M., Lems, W., Metsios, G., Kitas, G. D., Dekker, J., Reimer, W. S. O., Jorstad, H., L'ami, M. J., Heslinga, M. & Nurmohamed, M., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1061-1061

Research output: Contribution to journalMeeting AbstractAcademic

Balancing benefits and risks in the era of biologics

Adami, G., Saag, K. G., Chapurlat, R. D., Guañabens, N., Haugeberg, G., Lems, W. F., Matijevic, R., Peel, N., Poddubnyy, D. & Geusens, P., 1 Jan 2019, In : Therapeutic Advances in Musculoskeletal Disease. 11, 11.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Bone health, an often forgotten comorbidity in systemic lupus erythematosus: A comment on the new recommendations

Orsolini, G., Bultink, I. E. M., Adami, G., Fassio, A., Viapiana, O., Giollo, A., Gatti, D. & Rossini, M., 3 Jul 2019, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Can personalized use of NSAIDs be a reality in the clinic?

Nurmohamed, M. T., 1 Jul 2019, In : Nature Reviews Rheumatology. 15, 7, p. 387-388

Research output: Contribution to journalArticleAcademicpeer-review

Cardiovascular disease is associated with activity limitations in osteoarthritis patients

van den Oever, I. A. M., Visman, I. M., de Rooij, M., Roorda, L. D., Lems, WF., Nurmohamed, MT., Dekker, J., van der Leeden, M. & van der Esch, M., 2019, In : International Journal of Clinical Rheumatology. 14, 3, p. 99 104 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cardiovascular Event Risk in Rheumatoid Arthritis is higher than in Type 2 Diabetes

Agca, R., Hopman, LHGA., Laan, KCJ., van Halm, VP., Peters, MJL., Smulders, YM., Dekker, J. M., Nijpels, MGAAM., Stehouwer, C. D. A., Voskuyl, AE., Boers, M., Lems, WF. & Nurmohamed, MT., 15 May 2019, In : Journal of Rheumatology.

Research output: Contribution to journalArticleAcademicpeer-review

Cardiovascular risk in ankylosing spondylitis and the effect of anti-TNF drugs: a narrative review

Atzeni, F., Nucera, V., Galloway, J., Zoltán, S. & Nurmohamed, M., 2019, In : Expert Opinion on Biological Therapy.

Research output: Contribution to journalReview articleAcademicpeer-review

Common mechanisms and holistic care in atherosclerosis and osteoporosis 11 Medical and Health Sciences 1103 Clinical Sciences

Szekanecz, Z., Raterman, H. G., Petho, Z. & Lems, W. F., 2019, In : Arthritis Research and Therapy. 21, 1, 15.

Research output: Contribution to journalReview articleAcademicpeer-review

Core domain Set selection according to OMERACT filter 2.1: The OMERACT methodology

Maxwell, L. J., Beaton, D. E., Shea, B. J., Wells, G. A., Boers, M., Grosskleg, S., Bingham, C. O., Conaghan, P. G., D’Agostino, M. A., de Wit, M., Gossec, L., March, L., Simon, L. S., Singh, J. A., Strand, V. & Tugwell, P., 2019, In : Journal of Rheumatology. 46, 8, p. 1014-1020

Research output: Contribution to journalArticleAcademicpeer-review

Creatine kinase and blood pressure in women with a history of early-onset preeclampsia

Horjus, D. L., Bokslag, A., Hooijberg, F., Hutten, B. A., Middeldorp, S. & de Groot, C. J. M., 1 Jan 2019, In : Pregnancy Hypertension. 15, p. 118-122

Research output: Contribution to journalArticleAcademicpeer-review

Current Treatments and New Developments in the Management of Glucocorticoid-induced Osteoporosis

Raterman, H. G., Bultink, I. E. M. & Lems, W. F., 2019, In : Drugs. 79, 10, p. 1065-1087

Research output: Contribution to journalReview articleAcademicpeer-review

Decreased Pain and Improved Dynamic Knee Instability Mediate the Beneficial Effect of Wearing a Soft Knee Brace on Activity Limitations in Patients With Knee Osteoarthritis

Cudejko, T., van der Esch, M., van den Noort, J. C., Rijnhart, J. J. M., van der Leeden, M., Roorda, L. D., Lems, W., Waddington, G., Harlaar, J. & Dekker, J., 1 Aug 2019, In : Arthritis Care & Research. 71, 8, p. 1036-1043 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Denosumab Versus Risedronate in Glucocorticoid-Induced Osteoporosis: Final Results of a Twenty-Four–Month Randomized, Double-Blind, Double-Dummy Trial

Saag, K. G., Pannacciulli, N., Geusens, P., Adachi, J. D., Messina, O. D., Morales-Torres, J., Emkey, R., Butler, P. W., Yin, X. & Lems, W. F., 2019, In : Arthritis and Rheumatology. 71, 7, p. 1174-1184

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis

Hu, Y., Wang, B., Shen, J., Low, S. A., Putt, K. S., Niessen, H. W. M., Matteson, E. L., Murphy, L., Ruppert, C., Jansen, G., Oliver, S. J., Feng, Y., Dimitrov, D. S., Nickerson-Nutter, C. & Low, P. S., 7 Jun 2019, In : Arthritis Research and Therapy. 21, 1, 143.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

DEVELOPMENT AND TESTING OF A SMARTPHONE APPLICATION TO SELF-MONITOR DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS

Seppen, B., L'ami, M. J., Rico, S., Ter Wee, M., Turkstra, F., Roorda, L. D., Catarinella, F., van Schaardenburg, D., Nurmohamed, M., Boers, M. & Bos, W. H., Jun 2019, In : Annals of the Rheumatic Diseases. 78, p. 1384-1384

Research output: Contribution to journalMeeting AbstractAcademic

Dietary Interventions for Gout and Effect on Cardiovascular Risk Factors: A Systematic Review

Vedder, D., Walrabenstein, W., Heslinga, M., de Vries, R., Nurmohamed, M., van Schaardenburg, D. & Gerritsen, M., 2019, In : Nutrients. 11, 12

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Dietary protein intake and upper leg muscle strength in subjects with knee osteoarthritis: data from the osteoarthritis initiative

de Zwart, A. H., van der Leeden, M., Roorda, L. D., Visser, M., van der Esch, M., Lems, W. F. & Dekker, J., 7 Feb 2019, In : Rheumatology International. 39, 2, p. 277-284

Research output: Contribution to journalArticleAcademicpeer-review

Dynamics of circulating TNF during adalimumab treatment using a drug-tolerant TNF assay

Berkhout, L. C., l'Ami, M. J., Ruwaard, J., Hart, M. H., Ooijevaar-de Heer, P., Bloem, K., Nurmohamed, M. T., van Vollenhoven, R. F., Boers, M., Alvarez, D. F., Smith, C. H., Wolbink, G. J. & Rispens, T., 30 Jan 2019, In : Science Translational Medicine. 11, 477, aat3356.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Dynamics of the type I interferon response during immunosuppressive therapy in rheumatoid arthritis

de Jong, T. D., Snoek, T., Mantel, E., van der Laken, C. J., van Vollenhoven, R. F. & Lems, W. F., 1 Jan 2019, In : Frontiers in Immunology. 10, APR, 902.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis

Ramwadhdoebe, T. H., van Baarsen, L. G. M., Boumans, M. J. H., Bruijnen, S. T. G., Safy, M., Berger, F. H., Semmelink, J. F., van der Laken, C. J., Gerlag, D. M., Thurlings, R. M. & Tak, P. P., 1 Jan 2019, In : Rheumatology (United Kingdom). 58, 6, p. 1075-1085

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Evaluation of the Short-, Mid-, and Long-Term Effects of Tofacitinib on Lymphocytes in Patients With Rheumatoid Arthritis

van Vollenhoven, R., Lee, E. B., Strengholt, S., Mojcik, C., Valdez, H., Krishnaswami, S., Biswas, P., Lazariciu, I., Hazra, A., Clark, J. D., Hodge, J., Wang, L. & Choy, E., 2019, In : Arthritis and Rheumatology. 71, 5, p. 685-695

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

F8-IL10: a new potential anti-rheumatic drug evaluated by a PET-guided translational approach

Bruijnen, S. T. G., Chandrupatla, D. M. S. H., Giovanonni, L., Neri, D., Vugts, D. J., Huisman, M. C., Hoekstra, O. S., Musters, R. J. P., Lammertsma, A. A., van Dongen, G. A. M. S., Jansen, G., Molthoff, C. F. M. & van der Laken, C. J., 7 Jan 2019, In : Molecular Pharmaceutics. 16, 1, p. 273-281

Research output: Contribution to journalArticleAcademicpeer-review

First-degree relatives of axial spondyloarthritis patients of the pre-SpA cohort would consider using medication in a preventive setting

de Winter, J. J., de Jong, H. M., Nieuwkerk, P. T., van der Horst-Bruinsma, I. E., Baeten, D. L. & van de Sande, M. G., 14 Mar 2019, In : Clinical Rheumatology. 38, 3, p. 755-759 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

First Validation of the Full PROMIS Pain Interference and Pain Behavior Item Banks in Patients with Rheumatoid Arthritis

Crins, M. H. P., Terwee, C. B., Westhovens, R., van Schaardenburg, D., Smits, N., Joly, J., Verschueren, P., Van der Elst, K., Dekker, J., Boers, M. & Roorda, L. D., 28 Sep 2019, In : Arthritis Care & Research.

Research output: Contribution to journalArticleAcademicpeer-review

Folate receptors and transporters: Biological role and diagnostic/therapeutic targets in cancer and other diseases

Frigerio, B., Bizzoni, C., Jansen, G., Leamon, C. P., Peters, G. J., Low, P. S., Matherly, L. H. & Figini, M., 12 Mar 2019, In : JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 38, 1, 125.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Folic acid conjugates of a bleomycin mimic for selective targeting of folate receptor positive cancer cells

Geersing, A., de Vries, R. H., Jansen, G., Rots, M. G. & Roelfes, G., 1 Aug 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 15, p. 1922-1927 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

FRI0409 FEMALE ANKYLOSING SPONDYLITIS PATIENTS HAVE A SUBSTANTIALLY LOWER TNFI TREATMENT RESPONSE THAN MEN

Rusman, T., Nurmohamed, M. T., Hoekstra, S. E., van Denderen, J. C., Wee, M. T. & Horst-Bruinsma, I. V. D., Jun 2019.

Research output: Contribution to conferencePaperAcademic

Glucocorticoides para artritis reumatoide en la era de las terapias dirigidas

Boers, M., 1 Nov 2019, In : Reumatologia Clinica. 15, 6, p. 311-314 4 p.

Research output: Contribution to journalArticleProfessional

Open Access

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

López-Isac, E., Acosta-Herrera, M., Kerick, M., Assassi, S., Satpathy, A. T., Granja, J., Mumbach, M. R., Beretta, L., Simeón, C. P., Carreira, P., Ortego-Centeno, N., Castellvi, I., Bossini-Castillo, L., Carmona, F. D., Orozco, G., Hunzelmann, N., Distler, J. R. H. W., Franke, A., Lunardi, C., Moroncini, G. & 32 othersGabrielli, A., de Vries-Bouwstra, J., Wijmenga, C., Koeleman, B. P. C., Nordin, A., Padyukov, L., Hoffmann-Vold, A-M., Lie, B., Ríos, R., Callejas, J. L., Vargas-Hitos, J. A., García-Portales, R., Camps, M. T., Fernández-Nebro, A., González-Escribano, M. F., García-Hernández, F. J., Castillo, M. J., Aguirre, M. A., Gómez-Gracia, I., Fernández-Gutiérrez, B., Rodríguez-Rodríguez, L., García de la Peña, P., Vicente, E., Andreu, J. L., Fernández de Castro, M., López-Longo, F. J., Martínez, L., Fonollosa, Voskuyl, A. E., European Scleroderma Group†, Australian Scleroderma Interest Group (ASIG) & Voskuyl, A. E., 1 Dec 2019, In : Nature Communications. 10, 1, 4955.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Identifying possible outcome domains from existing outcome measures to inform an OMERACT core domain set for safety in rheumatology trials

Klokker, L., Berthelsen, D. B., Woodworth, T., Andersen, K. M., Furst, D. E., Devoe, D., Williamson, P. R., Suarez-Almazor, M. E., Strand, V., Leong, A. L., Goel, N., Boers, M., Brooks, P. M., March, L., Sloan, V. S., Tugwell, P., Simon, L. S. & Christensen, R., 1 Sep 2019, In : Journal of Rheumatology. 46, 9, p. 1173-1178 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access