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Research Output 2001 2019

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2019

89 Zr-immuno-PET: towards a non-invasive clinical tool to measure target engagement of therapeutic antibodies in-vivo

Jauw, Y., o'Donoghue, J., Zijlstra, J., Hoekstra, O., Menke-van der Houven van Oordt, C. W., Morschhauser, F., Carrasquillo, J., Zweegman, S., Pandit-Taskar, N., Lammertsma, A., van Dongen, G., Boellaard, R., Weber, W. & Huisman, M., 30 May 2019, In : Journal of Nuclear Medicine. p. jnumed.118.224568

Research output: Contribution to journalArticleAcademicpeer-review

A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Hansson, O., Nordberg, A., Jacobs, A. H., IMBI Project, Bottlaender, M., Brooks, D., Carroll, M. A., Chalon, S., Gee, A., Gerhard, A., Halldin, C., Herholz, K., Herth, M. M., Hinz, R. & 13 othersKnudsen, G. M., Kuhnast, B., López-Picón, F., Moresco, R. M., Pappata, S., Rinne, J. O., Rodriguez-Vieitez, E., Santiago-Ribeiro, M. J., Turkheimer, F. E., van Laere, K., Varrone, A., Vercouillie, J. & Winkeler, A., 1 Aug 2019, In : Alzheimer's and Dementia. 15, 8, p. 1081-1103

Research output: Contribution to journalArticleAcademicpeer-review

Application of advanced brain positron emission tomography–based molecular imaging for a biological framework in neurodegenerative proteinopathies

Perani, D., Iaccarino, L., Jacobs, A. H., Lammertsma, A. A., Nordberg, A., Windhorst, A. D., Gerhard, A., Winkeler, A., Gee, A., Kuhnast, B., Halldin, C., Brooks, D., Rodriguez-Vieitez, E., Turkheimer, F. E., López-Picón, F., Knudsen, G. M., Vercouillie, J., Rinne, J. O., Herholz, K., van Laere, K. & 11 othersSantiago-Ribeiro, M. J., Herth, M. M., Carroll, M. A., Bottlaender, M., Hansson, O., Edison, P., Hinz, R., Boellaard, R., Moresco, R. M., Pappata, S. & IMBI Brain Imaging Working Group, 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 327-332

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Assessment of simplified methods for quantification of 18F-FDHT uptake in patients with metastatic castration-resistant prostate cancer

Kramer, G. M., Yaqub, M., Vargas, H. A., Schuit, R. C., Windhorst, A. D., van den Eertwegh, A. J. M., van der Veldt, A. A. M., Bergman, A. M., Burnazi, E. M., Lewis, J. S., Chua, S., Staton, K. D., Beattie, B. J., Humm, J. L., Davis, I. D., Weickhardt, A. J., Scott, A. M., Morris, M. J., Hoekstra, O. S. & Lammertsma, A. A., 1 Sep 2019, In : Journal of Nuclear Medicine. 60, 9, p. 1221-1227

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of the Novel PET Tracer [C-11]HACH242 for Imaging the GluN2B NMDA Receptor in Non-Human Primates

van der Aart, J., Yaqub, M., Kooijman, E. J. M., Bakker, J., Langermans, J. A. M., Schuit, R. C., Hofman, M. B. M., Christiaans, J. A. M., Lammertsma, A. A., Windhorst, A. D. & van Berckel, B. N. M., 15 Aug 2019, In : Molecular Imaging and Biology. 21, 4, p. 676-685

Research output: Contribution to journalArticleAcademicpeer-review

F8-IL10: a new potential anti-rheumatic drug evaluated by a PET-guided translational approach

Bruijnen, S. T. G., Chandrupatla, D. M. S. H., Giovanonni, L., Neri, D., Vugts, D. J., Huisman, M. C., Hoekstra, O. S., Musters, R. J. P., Lammertsma, A. A., van Dongen, G. A. M. S., Jansen, G., Molthoff, C. F. M. & van der Laken, C. J., 7 Jan 2019, In : Molecular Pharmaceutics. 16, 1, p. 273-281

Research output: Contribution to journalArticleAcademicpeer-review

Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies

Heeman, F., Yaqub, M., Lopes Alves, I., Heurling, K., Berkhof, J., Gispert, J. D., Bullich, S., Foley, C., Lammertsma, A. A. & AMYPAD Consortium, 27 Mar 2019, In : EJNMMI Research. 9, 1, p. 32

Research output: Contribution to journalArticleAcademicpeer-review

Quantification of PET Studies

Lammertsma, A. A., 14 Jan 2019, In : Journal of Nuclear Cardiology.

Research output: Contribution to journalArticleAcademicpeer-review

Semi-quantitative cerebral blood flow parameters derived from non-invasive [15O]H2O PET studies

Koopman, T., Yaqub, M., Heijtel, D. F., Nederveen, A. J., van Berckel, B. N., Lammertsma, A. A. & Boellaard, R., 1 Jan 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 1, p. 163-172

Research output: Contribution to journalArticleAcademicpeer-review

2018

[18F]NaF PET/CT scan as an early marker of heterotopic ossification in fibrodysplasia ossificans progressiva

Eekhoff, E. M. W., Botman, E., Coen Netelenbos, J., de Graaf, P., Bravenboer, N., Micha, D., Pals, G., de Vries, T. J., Schoenmaker, T., Hoebink, M., Lammertsma, A. A. & Raijmakers, P. G. H. M., Apr 2018, In : Bone.

Research output: Contribution to journalArticleAcademicpeer-review

3'-Deoxy-3'-[18F]Fluorothymidine Positron Emission Tomography Depicts Heterogeneous Proliferation Pathology in Idiopathic Pulmonary Arterial Hypertension Patient Lung

Ashek, A., Spruijt, O. A., Harms, H. J., Lammertsma, A. A., Cupitt, J., Dubois, O., Wharton, J., Dabral, S., Pullamsetti, S. S., Huisman, M. C., Frings, V., Boellaard, R., de Man, F. S., Botros, L., Jansen, S., Vonk Noordegraaf, A., Wilkins, M. R., Bogaard, H. J. & Zhao, L., 2018, In : Circulation. Cardiovascular imaging. 11, 8, p. e007402

Research output: Contribution to journalArticleAcademicpeer-review

An exploratory clinical study of p38α kinase inhibition in Alzheimer's disease

Scheltens, P., Prins, N., Lammertsma, A., Yaqub, M., Gouw, A., Wink, A. M., Chu, H. M., van Berckel, B. N. M. & Alam, J., 1 Apr 2018, In : Annals of Clinical and Translational Neurology. 5, 4, p. 464-473 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Assessment of target-mediated uptake with immuno-PET: analysis of a phase I clinical trial with an anti-CD44 antibody

Jauw, Y. W. S., Huisman, M. C., Nayak, T. K., Vugts, D. J., Christen, R., Naegelen, V. M., Ruettinger, D., Heil, F., Lammertsma, A. A., Verheul, H. M. W., Hoekstra, O. S., van Dongen, G. A. M. S. & van Oordt, C. W. M. D. H., 22 Jan 2018, In : EJNMMI Research. 8, 6.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project

de Wilde, A., van der Flier, W. M., Pelkmans, W., Bouwman, F., Verwer, J., Groot, C., van Buchem, M. M., Zwan, M., Ossenkoppele, R., Yaqub, M., Kunneman, M., Smets, E. M. A., Barkhof, F., Lammertsma, A. A., Stephens, A., van Lier, E., Biessels, G. J., van Berckel, B. N. & Scheltens, P., 1 Sep 2018, In : JAMA Neurology. p. 1062-1070 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Effect of Plaque Burden and Morphology on Myocardial Blood Flow and Fractional Flow Reserve

Driessen, R. S., Stuijfzand, W. J., Raijmakers, P. G., Danad, I., Min, J. K., Leipsic, J. A., Ahmadi, A., Narula, J., van de Ven, P. M., Huisman, M. C., Lammertsma, A. A., van Rossum, A. C., van Royen, N. & Knaapen, P., 6 Feb 2018, In : Journal of the American College of Cardiology. 71, 5, p. 499-509 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

van der Aart, J., Golla, S. S. V., van der Pluijm, M., Schwarte, L. A., Schuit, R. C., Klein, P. J., Metaxas, A., Windhorst, A. D., Boellaard, R., Lammertsma, A. A. & van Berckel, B. N. M., 1 Jan 2018, In : EJNMMI Research. 8, 69.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Flare-Up After Maxillofacial Surgery in a Patient With Fibrodysplasia Ossificans Progressiva: An [18F]-NaF PET/CT Study and a Systematic Review

Eekhoff, E. M. W., Netelenbos, J. C., de Graaf, P., Hoebink, M., Bravenboer, N., Micha, D., Pals, G., de Vries, T. J., Lammertsma, A. A., Raijmakers, P. G. & van Es, R. J., Jan 2018, In : JBMR Plus. 2, 1, p. 55-58 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease

Scheltens, N. M. E., van der Weijden, K., Adriaanse, S. M., van Assema, D., Oomen, P. P., Krudop, W. A., Lammertsma, A. A., Barkhof, F., Koene, T., Teunissen, C. E., Scheltens, P., van der Flier, W. M., Pijnenburg, Y. A. L., Yaqub, M., Ossenkoppele, R. & van Berckel, B. N. M., 1 Jan 2018, In : NeuroImage: Clinical. 19, p. 625-632 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Identification of the allosteric P2X receptor antagonist [C]SMW139 as a PET tracer of microglial activation

Janssen, B., Vugts, D. J., Wilkinson, S. M., Ory, D., Chalon, S., Hoozemans, J. J. M., Schuit, R. C., Beaino, W., Kooijman, E. J. M., van den Hoek, J., Chishty, M., Doméné, A., Van der Perren, A., Villa, A., Maggi, A., Molenaar, G. T., Funke, U., Shevchenko, R. V., Baekelandt, V., Bormans, G. & 3 othersLammertsma, A. A., Kassiou, M. & Windhorst, A. D., 26 Apr 2018, In : Scientific Reports. 8, 1, p. 6580

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate

Chandrupatla, D. M. S. H., Jansen, G., Mantel, E., Low, P. S., Matsuyama, T., Musters, R. P., Windhorst, A. D., Lammertsma, A. A., Molthoff, C. F. M. & van der Laken, C. J., 2018, In : Contrast media & molecular imaging. 2018, 8092781.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Improving metabolic stability of fluorine-18 labeled verapamil analogs

Raaphorst, R. M., Luurtsema, G., Schokker, C. J., Attia, K. A., Schuit, R. C., Elsinga, P. H., Lammertsma, A. A. & Windhorst, A. D., 30 Jul 2018, In : Nuclear Medicine and Biology. 64-65, p. 47-56 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access