Alexandre Voskuyl

PROF.DR., (Principal Investigator)

20012020

Research output per year

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Research Output

2020

A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn’s disease

González-Serna, D., Ochoa, E., López-Isac, E., Julià, A., Degenhardt, F., Ortego-Centeno, N., Radstake, T. R. D. J., Franke, A., Marsal, S., Mayes, M. D., Martín, J., Márquez, A., Assassi, S., Zhou, X., Tan, F. K., Arnett, F. C., Reveille, J. D., Gorlova, O., Chen, W. V., Ying, J. & 69 others, Gregersen, P. K., Lee, A. T., Voskuyl, A. E., de Vries-Bouwstra, J., Magro-Checa, C., Broen, J., Koeleman, B. P. C., Simeón, C. P., Fonollosa, V., Guillén, A., Carreira, P., Castellví, I., González-Gay, M. A., Ríos, R., Callejas-Rubio, J. L., Vargas-Hitos, J. A., García-Portales, R., Camps, M. T., Fernández-Nebro, A., González-Escribano, M. F., García-Hernández, F. J., Castillo, M. J., Aguirre, M. Á., Gómez-Gracia, I., Rodríguez-Rodríguez, L., Fernández-Gutiérrez, B., de la Peña, P. G., Vicente, E., Andreu, J. L., Fernández de Castro, M., López-Longo, F. J., Martínez, L., Espinosa, G., Tolosa, C., Pros, A., Rodríguez-Carballeira, M., Narváez, F. J., Rubio-Rivas, M., Ortiz-Santamaría, V., Madroñero, A. B., Díaz, B., Trapiella, L., Sousa, A., Egurbide, M. V., Fanlo-Mateo, P., Sáez-Comet, L., Díaz-González, F., Hernández, V., Beltrán, E., Román-Ivorra, J. A., Grau, E., Alegre-Sancho, J. J., Blanco-García, F. J., Oreiro, N., Freire, M., Balsa, A., Ortiz, A. M., Hunzelmann, N., Riemekasten, G., Distler, J. H. W., Witte, T., Airó, P., Beretta, L., Santaniello, A., Bellocchi, C., Lunardi, C., Moroncini, G., Gabrielli, A. & Scleroderma Genetic Consortium, 1 Dec 2020, In : Scientific Reports. 10, 1, 1862.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cardiovascular Event Risk in Rheumatoid Arthritis Compared with Type 2 Diabetes: A 15-year Longitudinal Study

Agca, R., Hopman, L. H. G. A., Laan, K. J. C., van Halm, V. P., Peters, M. J. L., Smulders, Y. M., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., Voskuyl, A. E., Boers, M., Lems, W. F. & Nurmohamed, M. T., 1 Mar 2020, In : Journal of Rheumatology. 47, 3, p. 316-324 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

First in man study of [18F]fluoro-PEG-folate PET: a novel macrophage imaging technique to visualize rheumatoid arthritis

Verweij, N. J. F., Yaqub, M., Bruijnen, S. T. G., Pieplenbosch, S., ter Wee, M. M., Jansen, G., Chen, Q., Low, P. S., Windhorst, A. D., Lammertsma, A. A., Hoekstra, O. S., Voskuyl, A. E. & van der Laken, C. J., 23 Jan 2020, In : Scientific Reports. 10, 1, 1047.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

How do patients with systemic sclerosis experience currently provided healthcare and how should we measure its quality?

Spierings, J., van den Ende, C. H. M., Schriemer, R. M., Bernelot Moens, H. J., van der Bijl, E. A., Bonte-Mineur, F., de Buck, M. P. D., de Kanter, M. A. E., Knaapen-Hans, H. K. A., van Laar, J. M., Mulder, U. D. J., Potjewijd, J., de Pundert, L. A. J., Schoonbrood, T. H. M., Schouffoer, A. A., Stel, A. J., Vercoutere, W., Voskuyl, A. E., de Vries-Bouwstra, J. K., Vonk, M. C. & 1 others, ARCH Study Group, 1 Jun 2020, In : Rheumatology (Oxford, England). 59, 6, p. 1226-1232 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Predictors of fatal and non-fatal cardiovascular events in ANCA-associated vasculitis: Data from the Toronto CanVasc cohort

Houben, E., Mendel, A., Carette, S., Voskuyl, A. E., Penne, E. L. & Pagnoux, C., 1 Jan 2020, In : Joint Bone Spine. 87, 3, 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Should vascular wall 18F-FDG uptake be adjusted for the extent of atherosclerotic burden?

Lensen, K-J. D. F., Voskuyl, A. E., Comans, E. F. I., van der Laken, C. J., Boellaard, R. & Smulders, Y. M., Mar 2020, In : International Journal of Cardiovascular Imaging. 36, 3, p. 545-551 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

9 Incidence and determinants of vertebral and peripheral fractures in patients with systemic lupus erythematosus: a prospective longitudinal cohort study

Hadiyen, F. E., Tsang-A-Sjoe, M. WP., Wee, M. M. T., Voskuyl, A. E., Lem, W. F. & Bultink, I. EM., Apr 2019.

Research output: Contribution to conferencePaperAcademic

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

López-Isac, E., Acosta-Herrera, M., Kerick, M., Assassi, S., Satpathy, A. T., Granja, J., Mumbach, M. R., Beretta, L., Simeón, C. P., Carreira, P., Ortego-Centeno, N., Castellvi, I., Bossini-Castillo, L., Carmona, F. D., Orozco, G., Hunzelmann, N., Distler, J. R. H. W., Franke, A., Lunardi, C., Moroncini, G. & 32 others, Gabrielli, A., de Vries-Bouwstra, J., Wijmenga, C., Koeleman, B. P. C., Nordin, A., Padyukov, L., Hoffmann-Vold, A-M., Lie, B., Ríos, R., Callejas, J. L., Vargas-Hitos, J. A., García-Portales, R., Camps, M. T., Fernández-Nebro, A., González-Escribano, M. F., García-Hernández, F. J., Castillo, M. J., Aguirre, M. A., Gómez-Gracia, I., Fernández-Gutiérrez, B., Rodríguez-Rodríguez, L., García de la Peña, P., Vicente, E., Andreu, J. L., Fernández de Castro, M., López-Longo, F. J., Martínez, L., Fonollosa, Voskuyl, A. E., European Scleroderma Group†, Australian Scleroderma Interest Group (ASIG) & Voskuyl, A. E., 1 Dec 2019, In : Nature Communications. 10, 1, 4955.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Suboptimal cardiovascular risk management in rheumatoid arthritis patients despite an explicit cardiovascular risk screening programme

Heslinga, M., van den Oever, I. A. M., Jonker, D. L., Griep, E. N., Griep-Wentink, H. R. M., Smulders, Y. M., Lems, W. F., Boers, M., Voskuyl, A. E., Peters, M. J. L., van Schaardenburg, D. & Nurmohamed, M. T., 3 Sep 2019, In : Scandinavian Journal of Rheumatology. 48, 5, p. 345-352 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

A multi-parameter response prediction model for rituximab in rheumatoid arthritis

de Jong, T. D., Sellam, J., Agca, R., Vosslamber, S., Witte, B. I., Tsang-A-Sjoe, M., Mantel, E., Bijlsma, J. W., Voskuyl, A. E., Nurmohamed, M. T., Verweij, C. L. & Mariette, X., 1 Mar 2018, In : Joint Bone Spine. 85, 2, p. 219-226 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cardiovascular events in anti-neutrophil cytoplasmic antibody-associated vasculitis: a meta-analysis of observational studies

Houben, E., Penne, E. L., Voskuyl, A. E., van der Heijden, J. W., Otten, R. H. J., Boers, M. & Hoekstra, T., Mar 2018, In : Rheumatology (Oxford, England). 57, 3, p. 555-562

Research output: Contribution to journalArticleAcademicpeer-review

FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC

Slart, R. H. J. A., Glaudemans, A. W. J. M., Chareonthaitawee, P., Treglia, G., Besson, F. L., Bley, T. A., Blockmans, D., Boellaard, R., Bucerius, J., Carril, J. M., Chen, W., Cid, M. C., Dagupta, B., Dorbala, S., Gheysens, O., Hyafil, F., Jain, S., Klink, T., van der Laken, C. J., Lomeña, F. & 31 others, Massollo, M., Prieto-González, S., Luqmani, R., Roivainen, A., Salvarani, C., Saraste, A., Schirmer, M., Verberne, H. J., Versari, A., Voskuyl, A. E., Walter, M. A., Camellino, D., Brouwer, E., Cimmino, M. A., Abidov, A., Agostini, D., Beanlands, R. S., Delgado-Bolton, R. C., Einstein, A. J., Gimelli, A., Miller, E. J., Sciagrà, R., Signore, A., Writing group, Reviewer group, Members of EANM Cardiovascular, Members of EANM Infection & Inflammation, Members of Committees, SNMMI Cardiovascular, Members of Council, PET Interest Group, Members of ASNC & EANM Committee Coordinator, 1 Jul 2018, In : European Journal of Nuclear Medicine and Molecular Imaging. 45, 7, p. 1250-1269 20 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2017

[18F]FLUORO-PEG-FOLATE PET: A NOVEL IMAGING TECHNIQUE TO VISUALIZE RHEUMATOID ARTHRITIS

Verweij, N., Bruijnen, S., Gent, Y., Huisman, M., Jansen, G., Molthoff, C., Chen, Q., Low, P., Windhorst, A., Lammertsma, A., Hoekstra, O., Voskuyl, A. & van der Laken, C., Jun 2017, p. 1020-1021.

Research output: Contribution to conferencePosterAcademic

A framework for remission in SLE: Consensus findings from a large international task force on definitions of remission in SLE (DORIS)

Van Vollenhoven, R., Voskuyl, A., Bertsias, G., Aranow, C., Aringer, M., Arnaud, L., Askanase, A., Balážová, P., Bonfa, E., Bootsma, H., Boumpas, D., Bruce, I., Cervera, R., Clarke, A., Coney, C., Costedoat-Chalumeau, N., Czirják, L., Derksen, R., Doria, A., Dörner, T. & 38 others, Fischer-Betz, R., Fritsch-Stork, R., Gordon, C., Graninger, W., Györi, N., Houssiau, F., Isenberg, D., Jacobsen, S., Jayne, D., Kuhn, A., Le Guern, V., Lerstrøm, K., Levy, R., MacHado-Ribeiro, F., Mariette, X., Missaykeh, J., Morand, E., Mosca, M., Inanc, M., Navarra, S., Neumann, I., Olesinska, M., Petri, M., Rahman, A., Rekvig, O. P., Rovensky, J., Shoenfeld, Y., Smolen, J., Tincani, A., Urowitz, M., Van Leeuw, B., Vasconcelos, C., Voss, A., Werth, V. P., Zakharova, H., Zoma, A., Schneider, M. & Ward, M., 1 Mar 2017, In : Annals of the Rheumatic Diseases. 76, 3, p. 554-561 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis

Carmona, F. D., Vaglio, A., Mackie, S. L., Hernández-Rodríguez, J., Monach, P. A., Castañeda, S., Solans, R., Morado, I. C., Narváez, J., Ramentol-Sintas, M., Pease, C. T., Dasgupta, B., Watts, R., Khalidi, N., Langford, C. A., Ytterberg, S., Boiardi, L., Beretta, L., Govoni, M., Emmi, G. & 32 others, Bonatti, F., Cimmino, M. A., Witte, T., Neumann, T., Holle, J., Schönau, V., Sailler, L., Papo, T., Haroche, J., Mahr, A., Mouthon, L., Molberg, Ø., Diamantopoulos, A. P., Voskuyl, A., Brouwer, E., Daikeler, T., Berger, C. T., Molloy, E. S., O'Neill, L., Blockmans, D., Lie, B. A., Mclaren, P., Vyse, T. J., Wijmenga, C., Allanore, Y., Koeleman, B. P. C., Spanish CGA Group, UKGCA Consortium, Vasculitis Clinical Research Consortium, UKGCA Consortium, Vasculitis Clinical Research Consortium & Vasculitis Clinical Research Consortium, 5 Jan 2017, In : American journal of human genetics. 100, 1, p. 64-74 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort

López-Isac, E., Bossini-Castillo, L., Palma, A. B., Assassi, S., Mayes, M. D., Simeón, C. P., Ortego-Centeno, N., Vicente, E., Tolosa, C., Rubio-Rivas, M., Román-Ivorra, J. A., Beretta, L., Moroncini, G., Hunzelmann, N., Distler, J. H. W., Riemekasten, G., de Vries-Bouwstra, J., Voskuyl, A. E., Radstake, T. R. D. J., Herrick, A. & 3 others, Denton, C. P., Fonseca, C. & Martín, J., 1 Jun 2017, In : Arthritis and Rheumatology. 69, 6, p. 1337-1338 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

An MIF promoter polymorphism is associated with susceptibility to pulmonary arterial hypertension in diffuse cutaneous systemic sclerosis

Bossini-Castillo, L., Campillo-Davo, D., Lopez-Isac, E., Carmona, F. D., Simeon, C. P., Carreira, P., Callejas-Rubio, J. L., Castellvi, I., Fernandez-Nebro, A., Rodriguez-Rodriguez, L., Rubio-Rivas, M., Garcia-Hernandez, F. J., Madronero, A. B., Beretta, L., Santaniello, A., Lunardi, C., Airo, P., Hoffmann-Vold, A. M., Kreuter, A., Riemekasten, G. & 11 others, Witte, T., Hunzelmann, N., Vonk, M. C., Voskuyl, A. E., De Vries-Bouwstra, J., Shiels, P., Herrick, A., Worthington, J., Radstake, T. R. D. J., Martin, J. & Spanish Scleroderma Group, 1 Oct 2017, In : Journal of Rheumatology. 44, 10, p. 1453-1457 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Anti-hinge antibodies recognize IgG subclass- and protease-restricted neoepitopes

Falkenburg, W. J. J., Van Schaardenburg, D., Ooijevaar-De Heer, P., Tsang-A-Sjoe, M. W. P., Bultink, I. E. M., Voskuyl, A. E., Bentlage, A. E. H., Vidarsson, G., Wolbink, G. & Rispens, T., 1 Jan 2017, In : Journal of Immunology. 198, 1, p. 82-93 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

CARDIOVASCULAR EVENTS IN ANCA-ASSOCIATED VASCULITIS: A META-ANALYSIS OF OBSERVATIONAL STUDIES

Houben, E., Penne, E. L., Voskuyl, A. E., van der Heijden, J. W., Boers, M. & Hoekstra, T., Jun 2017, p. 604-604.

Research output: Contribution to conferencePosterAcademic

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity

Tsang-A-Sjoe, M. W. P., Bultink, I. E. M., Korswagen, L. A., van der Horst, A., Rensink, I., de Boer, M., Hamann, D., Voskuyl, A. E. & Wouters, D., 1 Dec 2017, In : Molecular Immunology. 92, p. 125-131 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cost-utility of COBRA-light versus COBRA therapy in patients with early rheumatoid arthritis: The COBRA-light trial

Ter Wee, M. M., Coupé, V. M. H., Den Uyl, D., Blomjous, B. S., Kooijmans, E., Kerstens, P. J. S. M., Nurmohamed, M. T., Van Schaardenburg, DI., Voskuyl, A. E., Boers, M. & Lems, W. F., 1 Oct 2017, In : RMD Open. 3, 2, e000502.

Research output: Contribution to journalArticleAcademicpeer-review

FRI0623 [18F]fluoride PET-CT imaging of bone formation in ankylosing spondylitis before and after 12 weeks of ANTI-TNF treatment

Bruijnen, S., Verweij, N., Duivenvoorde, L. V., Bravenboer, N., Baeten, D., Denderen, C. V., van, I. D. H-B., Voskuyl, A., Ven, P. V. D., Bot, J., Boden, B., Lammertsma, A., Hoekstra, O., Raijmakers, P. & Laken, C. V. D., Jun 2017.

Research output: Contribution to conferencePaperAcademic

Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study

Kroese, S. J., Abheiden, C. N. H., Blomjous, B. S., Van Laar, J. M., Derksen, R. W. H. M., Bultink, I. E. M., Voskuyl, A. E., Lely, A. T., De Boer, M. A., De Vries, J. I. P. & Fritsch-Stork, R. D. E., 2017, In : Journal of Immunology Research. 2017, 8245879.

Research output: Contribution to journalArticleAcademicpeer-review

PREGNANCY OUTCOME IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS, A MULTICENTER COHORT-STUDY

Blomjous, B., Abheiden, C., Kroese, S., van Laar, J., Derksen, R., Bultink, I., Voskuyl, A., Lely, A., de Boer, M., de Vries, J. & Fritsch-Stork, R., Jun 2017, In : Annals of the Rheumatic Diseases. 76, p. 184-184

Research output: Contribution to journalMeeting AbstractAcademic

Protein array autoantibody profiles to determine diagnostic markers for neuropsychiatric systemic lupus erythematosus

van der Meulen, P. M., Barendregt, A. M., Cuadrado, E., Magro-Checa, C., Steup-Beekman, G. M., Meinema, D. S., Merlijn Van den Berg, J., Li, Q. Z., Baars, P. A., Wouters, D., Voskuyl, A. E., Ineke, I. R., Tom, T. W. & Kuijpers, T. W., 1 Aug 2017, In : Rheumatology (United Kingdom). 56, 8, p. 1407-1416 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Relation between duration of the prodromal phase and renal damage in ANCA-associated vasculitis

Houben, E., Groenland, S. L., Van Der Heijden, J. W., Voskuyl, A. E., Doodeman, H. J. & Penne, E. L., 29 Dec 2017, In : BMC Nephrology. 18, 1, 378.

Research output: Contribution to journalArticleAcademicpeer-review

Rheumatoid Arthritis Imaging on PET-CT Using a Novel Folate Receptor Ligand for Macrophage Targeting

Verweij, N., Bruijnen, S., Gent, Y., Huisman, M., Jansen, G., Molthoff, C., Chen, Q., Low, P., Windhorst, A., Lammertsma, A., Hoekstra, O., Voskuyl, A. & van der Laken, C., Oct 2017, In : Arthritis & rheumatology. 69

Research output: Contribution to journalArticleAcademicpeer-review

Screening for renal involvement in ANCA-associated vasculitis: Room for improvement?

Houben, E., van der Heijden, J. W., van Dam, B., Bax, W. A., Voskuyl, A. E. & Penne, E. L., 1 Jan 2017, In : Netherlands Journal of Medicine. 75, 1, p. 21-26 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Similar efficacy and safety of initial COBRA-light and COBRA therapy in rheumatoid arthritis: 4-year results from the COBRA-light trial

Konijn, N. P. C., van Tuyl, L. H. D., Boers, M., den Uyl, D., ter Wee, M. M., van der Wijden, L. K. M., Bultink, I. E. M., Kerstens, P. J. S. M., Voskuyl, A. E., van Schaardenburg, D., Nurmohamed, M. T. & Lems, W. F., 1 Sep 2017, In : Rheumatology (United Kingdom). 56, 9, p. 1586-1596 11 p.

Research output: Contribution to journalArticleAcademicpeer-review