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Research Output 1991 2019

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Tutu-van Furth, AM. & Tutu, M. A., 2019, In : The Lancet. 393, 10171, p. 529-530

Research output: Contribution to journalArticleAcademicpeer-review

Bacterial genotyping of CNS tuberculosis in South Africa: heterogenic M.tuberculosis infection and predominance of lineage 4

van Leeuwen, LM., Versteegen, P., Zaharie, S. D., Van Elsland, S. L., Streicher, E. M., Warren, R. M., van der Kuip, M. & Tutu-van Furth, AM., 2019, In : Journal of Clinical Microbiology.

Research output: Contribution to journalArticleAcademicpeer-review

Disclosure of HIV status to childen in South-Africa: a comprehensive analysis.

van Elsland, SL., Peters, RPH., Grobbelaar, N., Ketelo, P., Kok, M. O., Cotton, M. F. & Tutu-van Furth, AM., 2019, In : South African Journal of HIV Medicine. p. In press

Research output: Contribution to journalArticleAcademicpeer-review

Human parechovirus meningitis and gross-motor neurodevelopment in young children

van Hinsbergh, MT., de Crom, SCM., Lindeboom, R., Tutu-van Furth, AM. & Obihara, CC., 2019, In : European Journal of Pediatrics. In press

Research output: Contribution to journalArticleAcademicpeer-review

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

Borghini, L., Png, E., Binder, A., Wright, V. J., Pinnock, E., de Groot, R., Hazelzet, J., Emonts, M., Van der Flier, M., Schlapbach, L. J., Anderson, S., Fink, C., Carrol, E. D., Pollard, A. J., Coin, L. J., Kuijpers, T. W., Zenz, W., Levin, M., Hibberd, M. L., Davila, S. & 289 othersGormley, S., Hamilton, S., Herberg, J., Hourmat, B., Hoggart, C., Kaforou, M., Sancho-Shimizu, V., Abdulla, A., Agapow, P., Bartlett, M., Bellos, E., Eleftherohorinou, H., Galassini, R., Inwald, D., Mashbat, M., Menikou, S., Mustafa, S., Nadel, S., Rahman, R., Thakker, C., Bokhandi, S., Power, S., Barham, H., Pathan, N., Ridout, J., White, D., Thurston, S., Faust, S., Patel, S., McCorkell, J., Davies, P., Cratev, L., Navarra, H., Carter, S., Ramaiah, R., Patel, R., Tuffrey, C., Gribbin, A., McCready, S., Peters, M., Hardy, K., Standing, F., O'Neill, L., Abelake, E., Deep, A., Nsirim, E., Willis, L., Young, Z., Royad, C., White, S., Fortune, P. M., Hudnott, P., Alvez Gonzalez, F., Barral-Arca, R., Cebey-Lopez, M., Jose Curras-Tuala, M., Garcia, N., Garcia Vicente, L., Gomez-Carballa, A., Gomez Rial, J., Grela Beiroa, A., Justicia Grande, A., Leborans Iglesias, P., Martinez Santos, A. E., Martinon-Torres, N., Martinon Sanchez, J. M., Mosquera Perez, B., Obando Pacheco, P., Pardo-Seco, J., Pischedda, S., Rivero Calle, I., Rodriguez-Tenreiro, C., Redondo-Collazo, L., Seren Fernandez, S., Porto Silva, M. D. S., Vega, A., Beatriz Reyes, S., Leon Leon, M. C., Navarro Mingorance, A., Gabaldo Barrios, X., Onate Vergara, E., Concha Torre, A., Vivanco, A., Fernandez, R., Gimenez Sanchez, F., Sanchez Forte, M., Rojo, P., Ruiz Contreras, J., Palacios, A., Navarro, M., Alvarez Alvarez, C., Jose Lozano, M., Carreras, E., Brio Sanagustin, S., Neth, O., van Furth, A. M. T., van der Flier, M., Boeddha, N. P., Driessen, G. J. A., Pajkrt, D., Sanders, E. A. M., van de Beek, D., van der Ende, A., Philipsen, H. L. A., Adeel, A. O. A., Breukels, M. A., Brinkman, D. M. C., de Korte, C. C. M. M., de Vries, E., de Waal, W. J., Dekkers, R., Dings-Lammertink, A., Doedens, R. A., Donker, A. E., Dousma, M., Faber, T. E., Gerrits, G. P. J. M., Gerver, J. A. M., Heidema, J., Homan-van der Veen, J., Jacobs, M. A. M., Jansen, N. J. G., Kawczynski, P., Klucovska, K., Kneyber, M. C. J., Koopman-Keemink, Y., Langenhorst, V. J., Leusink, J., Loza, B. F., Merth, I. T., Miedema, C. J., Neeleman, C., Noordzij, J. G., Obihara, C. C., van Overbeek-van Gils, A. L. T., Poortman, G. H., Potgieter, S. T., Potjewijd, J., Rosias, P. P. R., Sprong, T., ten Tussher, G. W., Thio, B. J., Tramper-Stranders, G. A., van Deuren, M., van der Meer, H., van Kuppevelt, A. J. M., van Wermeskerken, A. M., Verwijs, W. A., Wolfs, T. F. W., Agyeman, P., Aebi, C., Berger, C., Giannoni, E., Stocker, M., Posfay-Barbe, K. M., Heininger, U., Bernhard-Stirnemann, S., Niederer-Loher, A., Kahlert, C., Hasters, P., Relly, C., Baer, W., Paulus, S., Frederick, H., Jennings, R., Johnston, J., Kenwright, R., Agbeko, R., Bojang, K., Sarr, I., Kebbeh, N., Sey, G., Saidykhan, M., Cole, F., Thomas, G., Antonio, M., Walcher, W., Geishofer, G., Klobassa, D., Martin, M., Pfurtscheller, K., Reiter, K., Roedl, S., Zobel, G., Zoehrer, B., Toepke, B., Fucik, P., Gabriel, M., Penzien, J. M., Diab, G., Miething, R., Deeg, K. H., Hammer, J., Varnholt, V., Schmidt, A., Bindl, L., Sillaber, U., Huemer, C., Meier, P., Simic-Schleicher, G., Markart, M., Pfau, E., Broede, H., Ausserer, B., Kalhoff, H., Arpe, V., Schweitzer-Krantz, S., Kasper, J-M., Loranth, K., Bittrich, H. J., Simma, B., Klinge, J., Fedlmaier, M., Weigand, N., Herting, E., Grube, R., Fusch, C., Gruber, A., Schimmel, U., Knaufer-Schiefer, S., Laessig, W., Hennenberger, A., von der Wense, A., Tillmann, R., Schwarick, J., Sitzmann, F. C., Streif, W., Mueller, H., Kurnik, P., Groneck, P., Weiss, U., Groeblacher-Roth, H., Bensch, J., Moser, R., Schwarz, R., Lenz, K., Hofmann, T., Goepel, W., Schulz, D., Berger, T., Hauser, E., Foerster, K. M., Peters, J., Nicolai, T. H., Kumlien, B., Beckmann, R., Seitz, C., Hueseman, D., Schuermann, R., Ta, V. H., Weikmann, E., Evert, W., Hautz, J., Seidenberg, J., Wocko, L., Luigs, P., Reiter, H-L., Quietzach, J., Koenig, M., Herrmann, J., Mitter, H., Seidler, E., Maak, B., Sperl, W., Zwiauer, K., Meissl, M., Koch, R., Cremer, M., Breuer, H. A., Goerke, W., Nossal, R., Pernice, W., Brangenberg, R., Salzer, H. R., Koch, H., Schaller, G., Paky, F., Strasser, F., Eitelberger, F., Sontheimer, D., Lischka, A., Kronberger, M., Dilch, A., Scheibenpflug, C., Bruckner, R., Mahler, K., Runge, K., Kunze, W. & Schermann, P., 6 May 2019, In : Scientific Reports. 9

Research output: Contribution to journalArticleAcademicpeer-review

Longitudinal Association Between Human Parechovirus Central Nervous System Infection and Gross-Motor Neurodevelopment in Young Children

van Hinsbergh, T. M. T., Elbers, R. G., van Furth, M. A. M. & Obihara, C. C. C., Feb 2019, In : Pediatric Infectious Disease Journal. 38, 2, p. 110-114

Research output: Contribution to journalArticleAcademicpeer-review

Microbial Evolutionary Medicine – from theory 1 to clinical practice. A consortium paper.

Andersen, SB., Shapiro, J., Vandenbroucke-Grauls, CMJE., de Vos, MGJ. & Tutu-van Furth, AM., 2019, In : Lancet Infectious Diseases. p. 1-11

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Paediatric ART Adherence in South Africa: A Comprehensive Analysis

van Elsland, S. L., Peters, R. P. H., Grobbelaar, N., Ketelo, P., Kok, M. O., Cotton, M. F. & van Furth, A. M., Feb 2019, In : AIDS and Behavior. 23, 2, p. 475-488

Research output: Contribution to journalArticleAcademicpeer-review

2018

A treatment-support intervention evaluated in South African paediatric populations with HIV infection or tuberculous meningitis

van Elsland, S. L., Peters, R. P. H., Kok, M. O., van Toorn, R., Springer, P., Cotton, M. F., Grobbelaar, C. J., Aarnoutse, R. & van Furth, A. M., 1 Oct 2018, In : Tropical Medicine and International Health. 23, 10, p. 1129-1140 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bacterial meningitis

el Tahir, O. & Tutu-van Furth, AM., 2018, In : BMJ best practise.

Research output: Contribution to journalArticleAcademicpeer-review

Cost-effectiveness of home-based vs. in-hospital treatment of paediatric tuberculous meningitis

Van Elsland, S. L., Van Dongen, S. I., Bosmans, J. E., Schaaf, H. S., Van Toorn, R. & Van Furth, A. M., 1 Oct 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 10, p. 1188-1195 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of a real-time PCR assay for detection and quantification of bacterial DNA directly in blood of preterm neonates with suspected late-onset sepsis

van den Brand, M., van den Dungen, F. A. M., Bos, M. P., van Weissenbruch, M. M., van Furth, A. M., de Lange, A., Rubenjan, A., Peters, R. P. H. & Savelkoul, P. H. M., 22 Apr 2018, In : Critical Care. 22, 1, 105.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genetic predisposition to infection in a case of atypical hemolytic uremic syndrome

Van Den Heuvel, L., Riesbeck, K., El Tahir, O., Gracchi, V., Kremlitzka, M., Morré, S. A., Van Furth, A. M., Singh, B., Okrój, M., Van De Kar, N., Blom, A. M. & Volokhina, E., 1 Jan 2018, In : Journal of human genetics. 63, 1, p. 93-96 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study

Martinón-Torres, F., Salas, A., Gómez Rial, J., Rivero-Calle, I., Palacios, A. & van Furth, A. M., 1 Jun 2018, In : The Lancet Child and Adolescent Health. 2, 6, p. 404-414 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Mycobacteria employ two different mechanisms to cross the blood-brain barrier

van Leeuwen, L. M., Boot, M., Kuijl, C., Picavet, D. I., van Stempvoort, G., van der Pol, S. M. A., de Vries, H. E., van der Wel, N. N., van der Kuip, M., van Furth, A. M., van der Sar, A. M. & Bitter, W., 1 Sep 2018, In : Cellular Microbiology. 20, 9, e1285820.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Bacterial meningitis

Tutu-van Furth, AM., 2017, In : BMJ best practise.

Research output: Contribution to journalArticleAcademic

Solar ultraviolet B exposure and global variation in tuberculosis incidence: An ecological analysis

Boere, T. M., Visser, D. H., Van Furth, A. M., Lips, P. & Cobelens, F. G. J., 1 Jun 2017, In : European Respiratory Journal. 49, 6, 1601979.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Antiretroviral treatment and time since HIV-1 diagnosis are associated with large artery stiffness in sub-Saharan African HIV-1 patients

Msoka, T. F., Van Guilder, G. P., Smulders, Y. M., van Furth, M., Bartlett, J. A. & van Agtmael, M. A., Dec 2016, In : Artery Research. 16, p. 34-41

Research output: Contribution to journalArticleAcademicpeer-review

A putative urinary biosignature for diagnosis and follow-up of tuberculous meningitis in children: outcome of a metabolomics study disclosing host-pathogen responses

Mason, S., van Furth, A. M. T., Solomons, R., Wevers, R. A., van Reenen, M. & Reinecke, C. J., Jul 2016, In : Metabolomics. 12, 7

Research output: Contribution to journalArticleAcademicpeer-review

Cerebrospinal fluid in tuberculous meningitis exhibits only the L-enantiomer of lactic acid

Mason, S., Reinecke, C. J., Kulik, W., van Cruchten, A., Solomons, R. & van Furth, A. M. T., 7 Jun 2016, In : BMC Infectious Diseases. 16

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic accuracy of a uniform research case definition for TBM in children: a prospective study

Solomons, R. S., Visser, D. H., Marais, B. J., Schoeman, J. F. & van Furth, A. M., Jul 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 7, p. 903-908

Research output: Contribution to journalArticleAcademicpeer-review

Enterovirus and parechovirus infection in children: a brief overview

de Crom, S. C. M., Rossen, J. W. A., van Furth, A. M. & Obihara, C. C., Aug 2016, In : European Journal of Pediatrics. 175, 8, p. 1023-1029

Research output: Contribution to journalArticleAcademicpeer-review

Genetic changes predisposing to complement dysregulation and infection may play role in a case of atypical hemolytic uremic syndrome

Volokhina, E., El Tahir, O., Komhoff, M., Morre, S., van Furth, M., Singh, B., Okroj, M., van de Kar, N., Riesbeck, K., Blom, A. & van den Heuvel, L., Oct 2016, In : Immunobiology. 221, 10, p. 1140-1140

Research output: Contribution to journalArticleAcademicpeer-review

Improving Global Child Health in the Light of the (Old) Millennium Development Goals and the (New) Sustainable Development Goals

Boele van Hensbroek, M. & van Furth, M., Aug 2016, In : Pediatric Infectious Disease Journal. 35, 8, p. 918-9 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prospective assessment of clinical symptoms associated with enterovirus and parechovirus genotypes in a multicenter study in Dutch children

de Crom, S. C. M., Rossen, J. W. A., de Moor, R. A., Veldkamp, E. J. M., van Furth, A. M. & Obihara, C. C., Apr 2016, In : Journal of Clinical Virology. 77, p. 15-20

Research output: Contribution to journalArticleAcademicpeer-review

Tuberculous meningitis in infants and children: Insights from nuclear magnetic resonance metabolomics

Mason, S., Reinecke, C. J., Solomons, R. & van Furth, A. M., 2016, In : SOUTH AFRICAN JOURNAL OF SCIENCE. 112, 3-4, p. 42-49

Research output: Contribution to journalArticleAcademicpeer-review

2015

A hypothetical astrocyte-microglia lactate shuttle derived from a H-1 NMR metabolomics analysis of cerebrospinal fluid from a cohort of South African children with tuberculous meningitis

Mason, S., van Furth, A. M., Mienie, L. J., Engelke, U. F. H., Wevers, R. A., Solomons, R. S. & Reinecke, C. J., 2015, In : Metabolomics. 11, 4, p. 822-837

Research output: Contribution to journalArticleAcademicpeer-review

Chest radiograph findings in children with tuberculous meningitis

Solomons, R. S., Goussard, P., Visser, D. H., Marais, B. J., Gie, R. P., Schoeman, J. F. & van Furth, A. M., 2015, In : International Journal of Tuberculosis and Lung Disease. 19, 2, p. 200-204

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostiek, behandeling en complicaties van bacteriële meningitis

Bijlsma, MW. & Tutu-van Furth, AM., 2015, In : Praktische Pediatrie. 12, p. 30-35

Research output: Contribution to journalArticleAcademicpeer-review

Host Immune Response to Tuberculous Meningitis

Visser, D. H., Solomons, R. S., Ronacher, K., van Well, G. T., Heymans, M. W., Walzl, G., Chegou, N. N., Schoeman, J. F. & van Furth, A. M., 2015, In : Clinical Infectious Diseases. 60, 2, p. 177-187

Research output: Contribution to journalArticleAcademicpeer-review

Improved diagnosis of childhood tuberculous meningitis using more than one nucleic acid amplification test

Solomons, R. S., Visser, D. H., Friedrich, S. O., Diacon, A. H., Hoek, K. G. P., Marais, B. J., Schoeman, J. F. & van Furth, A. M., 2015, In : International Journal of Tuberculosis and Lung Disease. 19, 1, p. 74-80

Research output: Contribution to journalArticleAcademicpeer-review

The church and paediatric HIV care in rural South Africa: a qualitative study

Norder, W. A. J., Peters, R. P. H., Kok, M. O., van Elsland, S. L., Struthers, H. E., Tutu, M. A. & van Furth, A. M., 2015, In : Aids Care. 27, 11, p. 1404-1409

Research output: Contribution to journalArticleAcademicpeer-review

The diagnostic value of cerebrospinal fluid chemistry results in childhood tuberculous meningitis

Solomons, R. S., Visser, D. H., Donald, P. R., Marais, B. J., Schoeman, J. F. & van Furth, A. M., 2015, In : Child's Nervous System. 31, 8, p. 1335-1340

Research output: Contribution to journalArticleAcademicpeer-review

2014

Commercial nucleic acid amplification tests in tuberculous meningitis-a meta-analysis

Solomons, R. S., van Elsland, S. L., Visser, D. H., Hoek, K. G. P., Marais, B. J., Schoeman, J. F. & van Furth, A. M., 2014, In : Diagnostic microbiology and infectious disease. 78, 4, p. 398-403

Research output: Contribution to journalArticleAcademicpeer-review

Development of a multiplex real-time PCR assay for the rapid diagnosis of neonatal late onset sepsis

van den Brand, M., Peters, R. P. H., Catsburg, A., Rubenjan, A., Broeke, F. J., van den Dungen, F. A. M., van Weissenbruch, M. M., van Furth, A. M., Koressaar, T., Remm, M., Savelkoul, P. H. M. & Bos, M. P., 2014, In : Journal of Microbiological Methods. 106, p. 8-15

Research output: Contribution to journalArticleAcademicpeer-review

KEMREP: A New Qualitative Method for the Assessment of an Analyst’s Ability to Generate a Metabolomics Data Matrix by Gas Chromatography– Mass Spectrometry

Mason, S., Moutloatse, G., van Furth, A. M., Solomons, R. S., van Reenen, M., Reinecke, C. & Koekemoer, G., 2014, In : Current Metabolomics. 2, 1, p. 15-26

Research output: Contribution to journalArticleAcademicpeer-review

Lipoarabinomannan enzyme-linked immunosorbent assay for early diagnosis of childhood tuberculous meningitis

Blok, N., Visser, D. H., Solomons, R., van Elsland, S. L., den Hertog, A. L. & van Furth, A. M., 2014, In : International Journal of Tuberculosis and Lung Disease. 18, 2, p. 205-210

Research output: Contribution to journalArticleAcademicpeer-review

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.

van Leeuwen, L. M., van der Kuip, M., Youssef, S. A., de Bruin, A., Bitter, W., van Furth, A. M. & van der Sar, A. M., 2014, In : Disease Models and Mechanisms. 7, 9, p. 1111-1122

Research output: Contribution to journalArticleAcademicpeer-review

Quality of life and its determinants in Preschool children with Down syndrome

Weijerman, M. E., van Schie, P. E. M., Volman, M. J. M., van Furth, A. M. & Gemke, R. J. B. J., 1 Jan 2014, In : Journal of Intellectual Disability - Diagnosis and Treatment. 2, 1, p. 12-20 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Uniform Research Case Definition Criteria Differentiate Tuberculous and Bacterial Meningitis in Children

Solomons, R. S., Wessels, M., Visser, D. H., Donald, P. R., Marais, B. J., Schoeman, J. F. & van Furth, A. M., 2014, In : Clinical Infectious Diseases. 59, 11, p. 1574-1578

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin D deficiency among native Dutch and first- and second-generation non-Western immigrants

Huibers, M. H. W., Visser, D. H., Deckers, M. M. L., van Schoor, N. M., van Furth, A. M. & Wolf, B. H. M., 2014, In : European Journal of Pediatrics. 173, 5, p. 583-588

Research output: Contribution to journalArticleAcademicpeer-review

2013

Addition of host genetic variants in a prediction rule for post meningitis hearing loss in childhood: a model updating study

Sanders, M. S., de Jonge, R. C. J., Terwee, C. B., Heijmans, M. W., Koomen, I., Ouburg, S., Spanjaard, L., Morré, S. A. & van Furth, A. M., 2013, In : BMC Infectious Diseases. 13, 340.

Research output: Contribution to journalArticleAcademicpeer-review

Computational modeling of tuberculous meningitis reveals an important role for tumor necrosis factor-alpha

El-Kebir, M., van der Kuip, M., van Furth, A. M. & Kirschner, D. E., 2013, In : Journal of Theoretical Biology. 328, p. 43-53

Research output: Contribution to journalArticleAcademicpeer-review

Een kind met torticollis en insulten bij neuroborreliose

Van Breemen, M. S. M., Van Der Kuip, M., Wim Ang, C., Marceline Van Furth, A. & Wolf, N. I., 1 Jan 2013, In : Nederlands Tijdschrift voor Geneeskunde. 157, 3, A5157.

Research output: Contribution to journalArticleAcademicpeer-review

29 Downloads (Pure)

Independent validation of an existing model enables prediction of hearing loss after childhood bacterial meningitis

de Jonge, R. C. J., Sanders, M. S., Terwee, C. B., Heijmans, M. W., Gemke, R. J. B. J., Koomen, I., Spanjaard, L. & van Furth, A. M., 2013, In : PLoS ONE. 8, 3, e58707.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Prospective comparison of the detection rates of human enterovirus and parechovirus RT-qPCR and viral culture in different pediatric specimens

de Crom, S. C. M., Obihara, C. C., de Moor, R. A., Veldkamp, E. J. M., van Furth, A. M. & Rossen, J. W. A., 2013, In : Journal of Clinical Virology. 58, 2, p. 449-454

Research output: Contribution to journalArticleAcademicpeer-review

Seasonal variation in the incidence rate of tuberculous meningitis is associated with sunshine hours

Visser, D. H., Schoeman, J. F. & van Furth, A. M., 2013, In : Epidemiology and Infection. 141, 3, p. 459-462

Research output: Contribution to journalArticleAcademicpeer-review

Single Nucleotide Polymorphisms in Pathogen Recognition Receptor Genes Are Associated with Susceptibility to Meningococcal Meningitis in a Pediatric Cohort

van Well, G. T., Sanders, M. S., Ouburg, S., Kumar, V., van Furth, A. M. & Morré, S. A., 2013, In : PLoS ONE. 8, 5, e64252.

Research output: Contribution to journalArticleAcademicpeer-review