Anco Boonstra

DR., (Principal Investigator)

20002020

Research output per year

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Research Output

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Article

Combination therapy with oral treprostinil for pulmonary arterial hypertension: A double-blind placebo-controlled clinical trial

White, R. J., Jerjes-Sanchez, C., Meyer, G. M. B., Pulido, T., Sepulveda, P., Wang, K. Y., Grünig, E., Hiremath, S., Yu, Z., Zhang, G., Yip, W. L. J., Zhang, S., Khan, A., Deng, C. Q., Grover, R., Tapson, V. F., Svetliza, G. N., Lescano, A. J., Bortman, G. R., Diez, F. A. & 166 others, Botta, C. E., Fitzgerald, J., Feenstra, E., Kermeen, F. D., Keogh, A. M., Williams, T. J., Yousseff, P. P., Ng, B. J. H., Smallwood, D. M. N., Dwyer, N. B., Brown, M. R., Lang, I. M., Steringer-Mascherbauer, R., Arakaki, J. O., Campos, F., De Amorim Correa, R., De Souza, R., Meyer, G. M. B., Moreira, M. C., Yoo, H., Lapa, M. S., Swiston, J., Hirani, N., Mehta, S., Michelakis, E., Sepulveda, P., Zagolin, M., Liu, J., Zhang, S., Pan, L., Chunde, B., Qun, Y., Cheng, X., Yu, Z., Li, X., Hua, Y., Zhang, G., Zhu, X., Chen, Y., Cheng, Z., Yang, Y., Zhou, D., Shen, J., Nielsen-Kudsk, J. E., Carlsen, J., Bourdin, A., Hachulla, E., Dromer, C., Chaouat, A., Reynaud-Gauber, M., Seronde, M. F., Klose, H., Halank, M., Hoffken, G., Ewert, R., Rosenkranz, S., Grunig, E., Kruger, U., Kronsbein, J., Hauptmeier, B. M., Koch, A., Held, M., Lange, T. J., Neurohr, C., Wilkens, H., Wirtz, H., Konstantinides, S., Argyropoulou-Pataka, P., Orfanos, S., Hiremath, S., Kerkar, P. G., Suresh, P. V., Baxi, H. A., Oomman, A., Abhaichand, R. K., Edla Kumar, P. K., Chopra, V., Mehrotra, R., Rajput, R. K., Sawhney, J. S., Bimalendu, S., Sharma, K. H., Srinivasa Sastry, B. K., Kramer, M. R., Segel, M. J., Ben-Dov, I., Berkman, N., Yigla, M., Adir, Y., D'Alto, M., Vizza, C. D., Scelsi, L., Vitulo, P., Pulido, T. R., Jerjes-Sanchez, C., Boonstra, A., Vonk, M. C., Sobkowicz, B., Mularek-Kubzdela, T., Torbicki, A., Podolec, P., Teik, L. S., Yip, W. L. J., Chang, H. J., Kim, H. K., Park, J. B., Chang, S. A., Kim, D. K., Chung, W. J., Song, J. M., Nissell, M., Hjalmarsson, C., Rundqvist, B., Huang, W. C., Cheng, C. C., Hsu, C. H., Hsu, H. H., Wang, K. Y., Coghlan, J. G., Kiely, D. G., Pepke-Zaba, J. W., Lordan, J. L., Corris, P. A., Cadaret, L., Hansdottir, S., Oudiz, R. J., Badesch, D. B., Mathier, M., Schilz, R., Hill, N., Waxman, A., Markin, C. J., Zwicke, D. L., Fisher, M., Franco, V., Sood, N., Park, M. H., Allen, R., Feldman, J. P., Balasubramanian, V., Seeram, V. K., Bajwa, A., Thompson, A. B., Migliore, C., Elwing, J., McConnell, J. W., Mehta, J. P., Rahaghi, F. F., Rame, J. E., Khan, A., Patel, B., Oren, R. M., Klinger, J. R., Alnuaimat, H., Allen, S., Harvey, W., Eggert, M. S., Hage, A., Miller, C. E., Awdish, R., Cajigas, H., Grinnan, D., Trichon, B. H., McDonough, C., White, R. J. & Rischard, F., 15 Mar 2020, In : American Journal of Respiratory and Critical Care Medicine. 201, 6, p. 707-717 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diffusion capacity and BMPR2 mutations in pulmonary arterial hypertension

Trip, P., Girerd, B., Bogaard, H. J., de Man, F. S., Boonstra, A., Garcia, G., Humbert, M., Montani, D. & Vonk-Noordegraaf, A., 2014, In : European Respiratory Journal. 43, 4, p. 1195-1198

Research output: Contribution to journalArticleAcademicpeer-review

EPITOME-2: An open-label study assessing the transition to a new formulation of intravenous epoprostenol in patients with pulmonary arterial hypertension

Sitbon, O., Delcroix, M., Bergot, E., Boonstra, A., Granton, J., Langleben, D., Subias, P. E., Galie, N., Pfister, T., Lemarie, J. C. & Simonneau, G., 2014, In : The American Heart Journal. 167, 2, p. 210-217

Research output: Contribution to journalArticleAcademicpeer-review

The Right Ventricle Explains Sex Differences in Survival in Idiopathic Pulmonary Arterial Hypertension

Jacobs, W., van de Veerdonk, M. C., Trip, P., de Man, F. S., Heymans, M. W., Marcus, J. T., Kawut, S. M., Bogaard, H. J., Boonstra, A. & Vonk-Noordegraaf, A., 2014, In : Chest. 145, 6, p. 1230-1236

Research output: Contribution to journalArticleAcademicpeer-review

2013

Major bleeding with vitamin K antagonist anticoagulants in pulmonary hypertension

Henkens, I. R., Hazenoot, T., Boonstra, A., Huisman, M. V. & Vonk-Noordegraaf, A., 2013, In : European Respiratory Journal. 41, 4, p. 872-878

Research output: Contribution to journalArticleAcademicpeer-review

Prognostic Relevance of Changes in Exercise Test Variables in Pulmonary Arterial Hypertension

Groepenhoff, H., Vonk-Noordegraaf, A., van de Veerdonk, M. C., Boonstra, A., Westerhof, N. & Bogaard, H. J., 2013, In : PLoS ONE. 8, 9, e72013.

Research output: Contribution to journalArticleAcademicpeer-review

Risk Factors for Hemoptysis in Idiopathic and Hereditary Pulmonary Arterial Hypertension

Tio, D., Leter, E. M., Boerrigter, B. G., Boonstra, A., Vonk-Noordegraaf, A. & Bogaard, H. J., 2013, In : PLoS ONE. 8, 10, e78132.

Research output: Contribution to journalArticleAcademicpeer-review

Severely reduced diffusion capacity in idiopathic pulmonary arterial hypertension: patient characteristics and treatment responses

Trip, P., Nossent, E. J., de Man, F. S., van den Berk, I. A. H., Boonstra, A., Groepenhoff, H., Leter, E. M., Westerhof, N., Grünberg, K., Bogaard, H. J. & Vonk Noordegraaf, A., 2013, In : European Respiratory Journal. 42, 6, p. 1575-1585

Research output: Contribution to journalArticleAcademicpeer-review

2012

Dysregulated Renin-Angiotensin-Aldosterone System Contributes to Pulmonary Arterial Hypertension

de Man, F. S., Tu, L., Handoko, M. L., Rain, S., Ruiter, G., Francois, C., Schalij, I., Dorfmuller, P., Simonneau, G., Fadel, E., Perros, F., Boonstra, A., Postmus, P. E., van der Velden, J., Vonk Noordegraaf, A., Humbert, M., Eddahibi, S. & Guignabert, C., 2012, In : American Journal of Respiratory and Critical Care Medicine. 186, 8, p. 780-789

Research output: Contribution to journalArticleAcademicpeer-review

Progressive Changes in Right Ventricular Geometric Shortening and Long-term Survival in Pulmonary Arterial Hypertension

Mauritz, G. J., Kind, T., Marcus, J. T., Bogaard, H. J., van de Veerdonk, M., Postmus, P. E., Boonstra, A., Westerhof, N. & Vonk Noordegraaf, A., 2012, In : Chest. 141, 4, p. 935-943

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonary arterial hypertension with plexogenic arteriopathy in enzyme-substituted Gaucher disease

den Bakker, M. A., Grünberg, K., Boonstra, A., van Hal, P. T. & Hollak, C. E. M., 2012, In : Histopathology. 61, 2, p. 324-326

Research output: Contribution to journalArticleAcademicpeer-review

Ventilatory and Cardiocirculatory Exercise Profiles in COPD The Role of Pulmonary Hypertension

Boerrigter, B. G., Bogaard, H. J., Trip, P., Groepenhoff, H., Rietema, H., Holverda, S., Boonstra, A., Postmus, P. E., Westerhof, N. & Vonk Noordegraaf, A., 2012, In : Chest. 142, 5, p. 1166-1174

Research output: Contribution to journalArticleAcademicpeer-review

2011

Cardiac shunt in COPD as a cause of severe hypoxaemia: probably not so uncommon after all

Boerrigter, B. G., Boonstra, A., Westerhof, N., Postmus, P. E. & Vonk Noordegraaf, A., 2011, In : European Respiratory Journal. 37, 4, p. 960-962

Research output: Contribution to journalArticleAcademicpeer-review

Clinically significant change in stroke volume in pulmonary hypertension

van Wolferen, S. A., van de Veerdonk, M. C., Mauritz, G. J., Jacobs, W., Marcus, J. T., Marques, K. M. J., Bronzwaer, J. G. F., Heijmans, M. W., Boonstra, A., Postmus, P. E., Westerhof, N. & Noordegraaf, A. V., 2011, In : Chest. 139, 5, p. 1003-1009

Research output: Contribution to journalArticleAcademicpeer-review

Genetic counselling for pulmonary arterial hypertension: a matter of variable variability

Leter, E. M., Boonstra, A., Postma, F., Gille, J. J. P., Meijers-Heijboer, E. J. & Vonk Noordegraaf, A., 2011, In : Netherlands Heart Journal. 19, 2, p. 89-92

Research output: Contribution to journalArticleAcademic

Open Access
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Iron deficiency is common in idiopathic pulmonary arterial hypertension

Ruiter, G., Lankhorst, S., Boonstra, A., Postmus, P. E., Zweegman, S., Westerhof, N., van der Laarse, W. J. & Vonk Noordegraaf, A., 2011, In : European Respiratory Journal. 37, 6, p. 1386-1391

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonale hypertensie bij volwassenen in nederland: Feiten en cijfers

Translated title of the contribution: Pulmonary hypertension in adults in the Netherlands: Facts and figuresTrip, P., Boonstra, A. & Vonk-Noordegraaf, A., 1 Aug 2011, In : Hart Bulletin. 42, 4, p. 95-99 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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76 Downloads (Pure)

Supine-exercise-induced oxygen supply to the right myocardium is attenuated in patients with severe idiopathic pulmonary arterial hypertension

Wong, Y. Y., Raijmakers, P. G. H. M., Knaapen, P., Lubberink, J. M., Ruiter, G., Marcus, J. T., Boonstra, A., Lammertsma, A. A., Westerhof, N., van der Laarse, W. J. & Vonk Noordegraaf, A., 2011, In : Heart. 97, 24, p. 2069-2074

Research output: Contribution to journalArticleAcademicpeer-review

2010

Characteristics of Interstitial Fibrosis and Inflammatory Cell Infiltration in Right Ventricles of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

Overbeek, M. J., Mouchaers, K. T. B., Niessen, H. W. M., Hadi, A. M., Kupreishvili, K., Boonstra, A., Voskuyl, A. E., Belien, J. A. M., Smit, E. F., Dijkmans, B. A. C., Vonk Noordegraaf, A. & Grünberg, K., 2010, In : International Journal of Rheumatology. 2010, 604615.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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61 Downloads (Pure)

Exercise stroke volume and heart rate response differ in right and left heart failure

Groepenhoff, H., Westerhof, N., Jacobs, W., Boonstra, A., Postmus, P. E. & Vonk Noordegraaf, A., 2010, In : European Journal of Heart Failure. 12, 7, p. 716-720

Research output: Contribution to journalArticleAcademicpeer-review

Long-term outcomes in pulmonary arterial hypertension in the first-line epoprostenol or first-line bosentan era

Jacobs, W., Boonstra, A., van den Brand, M., Rosenberg, D. M., Schaaf, B., Postmus, P. E. & Vonk Noordegraaf, A., 2010, In : Journal of Heart and Lung Transplantation. 29, 10, p. 1150-1158

Research output: Contribution to journalArticleAcademicpeer-review

76 Downloads (Pure)

Right Ventricular Oscillatory Power Is a Constant Fraction of Total Power Irrespective of Pulmonary Artery Pressure

Saouti, N., Westerhof, N., Helderman, F., Marcus, J. T., Boonstra, A., Postmus, P. E. & Vonk Noordegraaf, A., 2010, In : American Journal of Respiratory and Critical Care Medicine. 182, 10, p. 1315-1320

Research output: Contribution to journalArticleAcademicpeer-review

Spontane pneumothorax bij vrouwen: denk aan thoracale endometriose – klinische les

Keizer, A. L., Deurloo, K. L., Boonstra, A., Melgers, I., Mijatovic, V. & Hompes, P. G. A., 2010, In : Modern Medicine. 34, p. 4-7

Research output: Contribution to journalArticleProfessional

2009

Addition of prostanoids in pulmonary hypertension deteriorating on oral therapy

Jacobs, W., Boonstra, A., Marcus, J. T., Postmus, P. E. & Vonk Noordegraaf, A., 2009, In : Journal of Heart and Lung Transplantation. 28, 3, p. 280-284

Research output: Contribution to journalArticleAcademicpeer-review

Effects of exercise training in patients with idiopathic pulmonary arterial hypertension

de Man, F. S., Handoko, M. L., Groepenhoff, H., van 't Hul, A. J., Abbink, J., Koppers, R. J. H., Grotjohan, H. P., Twisk, J. W. R., Bogaard, H. J., Boonstra, A., Postmus, P. E., Westerhof, N., van der Laarse, W. J. & Vonk Noordegraaf, A., 2009, In : European Respiratory Journal. 34, 3, p. 669-675

Research output: Contribution to journalArticleAcademicpeer-review

Low complication rates with totally implantable access port use in epoprostenol treatment of pulmonary hypertension

Dickinson, M. G., Scholvinck, E. H., Boonstra, A., Vonk noordegraaf, A., Snijder, R. J. & Berger, R. M. F., 2009, In : Journal of Heart and Lung Transplantation. 28, 3, p. 273-279

Research output: Contribution to journalArticleAcademicpeer-review

Myoglobin concentration in skeletal muscle fibers of chronic heart failure patients

Bekedam, M. A., van Beek-Harmsen, B. J. B., van Mechelen, W., Boonstra, A. & van der Laarse, W. J., 2009, In : Journal of Applied Physiology. 107, 4, p. 1138-1143

Research output: Contribution to journalArticleAcademicpeer-review

Predictors of mortality in inoperable chronic thromboembolic pulmonary hypertension

Saouti, N., de Man, F. S., Westerhof, N., Boonstra, A., Twisk, J. W. R., Postmus, P. E. & Vonk noordegraaf, A., 2009, In : Respiratory Medicine. 103, 7, p. 1013-1019

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonary arterial hypertension in limited cutaneous systemic sclerosis: a distinctive vasculopathy

Overbeek, M. J., Vonk, M. C., Boonstra, A., Voskuijl, A. E., Vonk Noordegraaf, A., Smit, E. F., Dijkmans, B. A. C., Postmus, P. E., Mooi, W. J., Heijdra, Y. & Grunberg, K., 2009, In : European Respiratory Journal. 34, 2, p. 371-379

Research output: Contribution to journalArticleAcademicpeer-review

RC time constant of single lung equals that of both lungs together: a study in chronic thromboembolic pulmonary hypertension

Saouti, N., Westerhof, N., Helderman, F., Marcus, J. T., Stergiopulos, N., Westerhof, B. E., Boonstra, A., Postmus, P. E. & Vonk noordegraaf, A., 2009, In : American Journal of Physiology. Heart and Circulatory Physiology. 297, 6, p. H2154-H2160

Research output: Contribution to journalArticleAcademicpeer-review

Relation of Resting Heart Rate to Prognosis in Patients With Idiopathic Pulmonary Arterial Hypertension

Henkens, I. R., van Wolferen, S. A., Gan, C. T., Boonstra, A., Swenne, C. A., Twisk, J. W. R., Kamp, O., van der Wall, E. E., Schalij, M. J., Vonk noordegraaf, A. & Vliegen, H. W., 2009, In : American Journal of Cardiology. 103, 10, p. 1451-1456

Research output: Contribution to journalArticleAcademicpeer-review

Sarcoplasmic reticulum ATPase activity in type I and II skeletal muscle fibres of chronic heart failure patients

Bekedam, M. A., van Beek-Harmsen, B. J. B., van Mechelen, W., Boonstra, A., Visser, F. C. & van der Laarse, W. J., 2009, In : International Journal of Cardiology. 133, 2, p. 185-190

Research output: Contribution to journalArticleAcademicpeer-review

2008

Acute effects of sildenafil on exercise pulmonary hemodynamics and capacity in patients with COPD

Holverda, S., Rietema, H., Bogaard, H. J., Westerhof, N., Postmus, P. E., Boonstra, A. & Vonk Noordegraaf, A., 2008, In : Pulmonary Pharmacology and Therapeutics. 21, 3, p. 558-564

Research output: Contribution to journalArticleAcademicpeer-review

Cardiopulmonary exercise test characteristics in patients with chronic obstructive pulmonary disease and associated pulmonary hypertension

Holverda, S., Bogaard, H. J., Groepenhoff, H., Postmus, P. E., Boonstra, A. & Vonk Noordegraaf, A., 2008, In : Respiration. 76, 2, p. 160-167

Research output: Contribution to journalArticleAcademicpeer-review

ECG monitoring of treatment response in pulmonary arterial hypertension patients

Henkens, I. R., Gan, C. T., van Wolferen, S. A., Hew, M., Boonstra, A., Twisk, J. W. R., Kamp, O., van der Wall, E. E., Schalij, M. J., Vonk Noordegraaf, A. & Vliegen, H. W., 2008, In : Chest. 134, 6, p. 1250-1257

Research output: Contribution to journalArticleAcademicpeer-review

Exercise testing to estimate survival in pulmonary hypertension

Groepenhoff, H., Vonk Noordegraaf, A., Boonstra, A., Spreeuwenberg, M. D., Postmus, P. E. & Bogaard, H. J., 2008, In : Medicine and Science in Sports and Exercise. 40, 10, p. 1725-1732

Research output: Contribution to journalArticleAcademicpeer-review

Improved ECG detection of presence and severity of right ventricular pressure load validated with cardiac magnetic resonance imaging

Henkens, I. R., Mouchaers, K. T. B., Vonk Noordegraaf, A., Boonstra, A., Swenne, C. A., Maan, A. C., Man, S. C., Twisk, J. W., van der Wall, E. E., Schalij, M. J. & Vliegen, H. W., 2008, In : American Journal of Physiology. Heart and Circulatory Physiology. 294, 5, p. H2150-H2157

Research output: Contribution to journalArticleAcademicpeer-review

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients

Stoop, J. N., Claassen, M. A., Woltman, A. M., Binda, R. S., Kuipers, E. J., Janssen, H. L., van der Molen, R. G. & Boonstra, A., 2008, In : Clinical Immunology. 129, 3, p. 419-427

Research output: Contribution to journalArticleAcademicpeer-review