20002020
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Research Output 2000 2020

2020

Red blood cell transfusion results in adhesion of neutrophils in human endotoxemia and in critically ill patients with sepsis

van Hezel, M. E., Boshuizen, M., Peters, A. L., Straat, M., Vlaar, A. P., Spoelstra - de Man, A. M. E., Tanck, M. W. T., Tool, A. T. J., Beuger, B. M., Kuijpers, T. W., Juffermans, N. P. & van Bruggen, R., 1 Feb 2020, In : Transfusion. 60, 2, p. 294-302 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019
Open Access

Adjuvant vitamin C for sepsis: mono or triple?

Spoelstra-de Man, A. M. E., Oudemans-van Straaten, H. M. & Berger, M. M., 2019, In : Critical care (London, England). 23, 1, p. 425

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy

Bauer, P. R., Chevret, S., Yadav, H., Mehta, S., Pickkers, P., Bukan, R. B., Rello, J., van de Louw, A., Klouche, K., Meert, A-P., Martin-Loeches, I., Marsh, B., Socias Crespi, L., Moreno-Gonzalez, G., Buchtele, N., Amrein, K., Balik, M., Antonelli, M., Nyunga, M., Barratt-Due, A. & 16 othersBergmans, D. C. J. J., Spoelstra-de Man, A. M. E., Kuitunen, A., Wallet, F., Seguin, A., Metaxa, V., Lemiale, V., Burghi, G., Demoule, A., Karvunidis, T., Cotoia, A., Klepstad, P. L., Møller, A. M., Mokart, D., Azoulay, E. & Efraim investigators and the Nine-I study group, 1 Jul 2019, In : European Respiratory Journal. 54, 1

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The SCARLET Randomized Clinical Trial

Vincent, J-L., Francois, B., Zabolotskikh, I., Daga, M. K., Lascarrou, J-B., Kirov, M. Y., Pettila, V., Wittebole, X., Meziani, F., Mercier, E., Lobo, S. M., Barie, P. S., Crowther, M., Esmon, C. T., Fareed, J., Gando, S., Gorelick, K. J., Levi, M., Mira, J-P., Opal, S. M. & 168 othersParrillo, J., Russell, J. A., Saito, H., Tsuruta, K., Sakai, T., Fineberg, D., Bertuzzi, R., Bellomo, R., Chapman, M., Ernest, D., Fletcher, J., French, C., Gowardman, J., Shehabi, Y., Venkatesh, B., Walsham, J., Vij, S., Chochrad, D., Creteur, J., Devriendt, J., Dive, A-M., Dugernier, T., Foret, F., Hoste, E., Jorens, P., Simon, M., Spapen, H., Vincent, J-L., Wittebole, X., Dias, F., Freire, A., Lobo, S. M., Simeonov, G., Stefanov, C., Aslanian, P., Berthiaume, L., Martin, C., Chittock, D., Dhar, A., Doig, C., Jones, G., Hall, R., Boyd, J., Shin, P., Wood, G., Zarychanski, R., Quinteros, G. A., Gasparovic, V., Husedzinovic, I., Balik, M., Burget, I., Dlouhy, P., Pachl, J., Karlsson, S., Laru-Sompa, R., Parviainen, I., Pettila, V., Ruokone, E., Skrifvars, M., Bohe, J., Dellamonica, J., Duguet, A., Durand-Gasselin, J., Fiancette, M., Francois, B., Joannes-Boyau, O., Lascarrou, J-B., Lefrant, J-Y., Mercat, A., Mercier, E., Meziani, F., Nseir, S., Quenot, J-P., Reignier, J., Schwebel, C., Marx, G., Zacharowski, K., Armaganidis, A., Komnos, A., Fejer, C., Appajigol, J., Behera, S. K., ChandraShekhar, S., Chowdhury, S., Daga, M. K., D'costa, P. M., Gupta, H. S. S., Iyer, S., Khan, Z. A., Mehta, M., Murthy, S., Sahu, S., Tewari, R., Bar-Lavie, Y., Bregman, G., Cohen, J., Eden, A., Einav-Bromiker, S., Jakobson, D., Nimrod, A., Beishuizen, A., Gerritsen, R., Pickkers, P., Rozendaal, W., Schoonderbeek, F. J., Spoelstra-de Man, A., van Zanten, A. R. H., Zijlstra, J. G., Freebairn, R., Henderson, S., McArthur, C., Young, P., Mayorga, M. J., Agafina, A. S., Bubnova, N., Gritsan, A., Kameneva, E., Katasonov, S. P., Khasanova, N. M., Kirov, M. Y., Kruberg, L., Kulabukhov, V. V., Lebedinskii, K., Spesivtsev, Y. A., Zabolotskikh, I., Rankovic, Z., Hong, S. B., Kim, M-J., Suh, G. Y., Yoo, C-G., Raventos, A. A., Ferrer, R., Vazquez, R. G., Hernandez, M., Piacentini, E., Rodriguez Oviedo, A. H., Garcia, M. S., Chan, M-C., Cheng, K-C., Yu, C-J., Eddleston, J., Smith, F. G., MacNaughton, P., Welters, I., Allen, K., Bochicchio, G., Carlson, R., Eaton, S., Fink, R., Gianatiempo, C., Kapoor, R., Kinasewitz, G., Koura, F., Krell, K., Martin, N., Nepal, S., Pastores, S. M., Peltan, I., Pullman, J., Seibert, A., Smith, J., Tennenberg, S., Wilhelm, A., Zeno, B., Allton, P., Carruthers, D., Matsuki, O. & Kayanoki, T., 28 May 2019, In : JAMA. 321, 20, p. 1993-2002

Research output: Contribution to journalArticleAcademicpeer-review

Expiratory muscle dysfunction in critically ill patients: towards improved understanding

Shi, Z-H., Jonkman, A., de Vries, H., Jansen, D., Ottenheijm, C., Girbes, A., Spoelstra-de Man, A., Zhou, J-X., Brochard, L. & Heunks, L., 1 Aug 2019, In : Intensive Care Medicine. 45, 8, p. 1061-1071 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Monitoring patient-ventilator breath contribution in the critically ill during neurally adjusted ventilatory assist: Reliability and improved algorithms for bedside use

Jonkman, A. H., Jansen, D., Gadgil, S., Keijzer, C., Girbes, A. R. J., Scheffer, G-J., van der Hoeven, J. G., Tuinman, P. R., Spoelstra-de Man, A. M. E., Sinderby, C. S. & Heunks, L. M. A., 1 Jan 2019, In : Journal of Applied Physiology. 127, 1, p. 264-271 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Predictors of short-term and long-term mortality in critically ill patients admitted to the intensive care unit following allogeneic stem cell transplantation

van der Heiden, P. L. J., Arbous, M. S., van Beers, E. J., van den Bergh, W. M., le Cessie, S., Demandt, A. M. P., Eefting, M., Hess, C., Kusadasi, N., Marijt, W. A. F., van Mook, W. N. K. A., Müller, M. C. A., Tuinman, P. R., van Vliet, M., van Westerloo, D. J., Blijlevens, N. M. A., Biemond, B. J., Vlaar, A. J., Spoelstra, A. M., Hilkens, M. & 2 othersKluin, H. C. & on behalf of the HEMA-ICU Study Group, 1 Mar 2019, In : Bone Marrow Transplantation. 54, 3, p. 418-424

Research output: Contribution to journalArticleAcademicpeer-review

Renal Resistive Index: Response to Shock and its Determinants in Critically Ill Patients

Rozemeijer, S., Haitsma Mulier, J. L. G., Röttgering, J. G., Elbers, P. W. G., Spoelstra-de Man, A. M. E., Tuinman, P. R., de Waard, M. C. & Oudemans-van Straaten, H. M., 1 Jul 2019, In : Shock. 52, 1, p. 43-51

Research output: Contribution to journalArticleAcademicpeer-review

The effect of red blood cell transfusion on iron metabolism in critically ill patients

Boshuizen, M., van Hezel, M. E., van Manen, L., Straat, M., Somsen, Y. B. O., Spoelstra-de Man, A. M. E., Blumberg, N., van Bruggen, R. & Juffermans, N. P., 1 Apr 2019, In : Transfusion. 59, 4, p. 1196-1201 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vitamin C and thiamine in critical illness

Spoelstra-de Man, A. M. E., Oudemans-van Straaten, H. M. & Elbers, P. W. G., 1 Sep 2019, In : BJA Education. 19, 9, p. 290-296 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2018

Assessing breathing effort in mechanical ventilation: physiology and clinical implications

de Vries, H., Jonkman, A., Shi, Z-H., Spoelstra-de Man, A. & Heunks, L., Oct 2018, In : Annals of Translational Medicine. 6, 19, p. 387 1 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Effects of hyperoxia on vascular tone in animal models: systematic review and meta-analysis

Smit, B., Smulders, Y. M., Eringa, E. C., Oudemans-van Straaten, H. M., Girbes, A. R. J., Wever, K. E., Hooijmans, C. R. & Spoelstra-de Man, A. M. E., 4 Aug 2018, In : Critical Care. 22, 1, p. 189

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hemodynamic effects of acute hyperoxia: Systematic review and meta-analysis

Smit, B., Smulders, Y. M., van der Wouden, J. C., Oudemans-van Straaten, H. M. & Spoelstra-de Man, A. M. E., 25 Feb 2018, In : Critical Care. 22, 1, 45.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Making sense of early high-dose intravenous vitamin C in ischemia/reperfusion injury

Spoelstra-de Man, A. M. E., Elbers, P. W. G. & Oudemans-van Straaten, H. M., 20 Mar 2018, In : Critical Care. 22, 1, p. 70

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Positive End-expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers

Lindqvist, J., van den Berg, M., van der Pijl, R., Hooijman, P. E., Beishuizen, A., Elshof, J., de Waard, M., Girbes, A., Spoelstra-de Man, A., Shi, Z-H., van den Brom, C., Bogaards, S., Shen, S., Strom, J., Granzier, H., Kole, J., Musters, R. J. P., Paul, M. A., Heunks, L. M. A. & Ottenheijm, C. A. C., 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 4, p. 472-485 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pro/con debate Conservative oxygenation in the intensive care unit: Con

Spoelstra-de Man, A. M. E., Mar 2018, In : Netherlands Journal of Critical Care. 26, 2, p. 86-87

Research output: Contribution to journalLetterAcademicpeer-review

Renal resistive index as an early predictor and discriminator of acute kidney injury in critically ill patients; A prospective observational cohort study

Haitsma Mulier, J. L. G., Rozemeijer, S., Röttgering, J. G., Spoelstra-de Man, A. M. E., Elbers, P. W. G., Tuinman, P. R., de Waard, M. C. & Oudemans-van Straaten, H. M., 2018, In : PLoS ONE. 13, 6, p. e0197967

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Respiratory Viruses in Invasively Ventilated Critically Ill Patients-A Prospective Multicenter Observational Study

Van Someren Gréve, F., Juffermans, N. P., Bos, L. D. J., Binnekade, J. M., Braber, A., Cremer, O. L., De Jonge, E., Molenkamp, R., Ong, D. S. Y., Rebers, S. P. H., Spoelstra-De Man, A. M. E., Van Der Sluijs, K. F., Spronk, P. E., Verheul, K. D., De Waard, M. C., De Wilde, R. B. P., Winters, T., De Jong, M. D. & Schultz, M. J., 1 Jan 2018, In : Critical Care Medicine. 46, 1, p. 29-36 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The cardiovascular effects of hyperoxia

Smit, B., 2018, 215 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Time trend analysis of long term outcome of patients with haematological malignancies admitted at dutch intensive care units

the HEMA-ICU Study Group, 1 Apr 2018, In : British Journal of Haematology. 181, 1, p. 68-76 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ultrasound imaging of the diaphragm: facts and future. A guide for the bedside clinician

Haaksma, M. E., Atmowihardjo, L., Heunks, L., Spoelstra-de Man, A. & Tuinman, P. R., Mar 2018, In : Netherlands Journal of Critical Care. 26, 2, p. 58-63

Research output: Contribution to journalReview articleAcademicpeer-review

Vitamin C: should we supplement?

Spoelstra-de Man, A. M. E., Elbers, P. W. G. & Oudemans-Van Straaten, H. M., Aug 2018, In : Current Opinion in Critical Care. 24, 4, p. 248-255 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin C Pharmacokinetics in Critically Ill Patients: A Randomized Trial of Four IV Regimens

de Grooth, H-J., Manubulu-Choo, W-P., Zandvliet, A. S., Spoelstra-de Man, A. M. E., Girbes, A. R., Swart, E. L. & Oudemans-van Straaten, H. M., Jun 2018, In : Chest. 153, 6, p. 1368-1377 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Acute hypoxemic respiratory failure in immunocompromised patients: the Efraim multinational prospective cohort study

Azoulay, E., Pickkers, P., Soares, M., Perner, A., Rello, J., Bauer, P. R., van de Louw, A., Hemelaar, P., Lemiale, V., Taccone, F. S., Martin Loeches, I., Meyhoff, T. S., Salluh, J., Schellongowski, P., Rusinova, K., Terzi, N., Mehta, S., Antonelli, M., Kouatchet, A., Barratt-Due, A. & 31 othersValkonen, M., Landburg, P. P., Bruneel, F., Bukan, R. B., Pène, F., Metaxa, V., Moreau, A. S., Souppart, V., Burghi, G., Girault, C., Silva, U. V. A., Montini, L., Barbier, F., Nielsen, L. B., Gaborit, B., Mokart, D., Chevret, S., Rabbat, A., Vinatier, I., Darmon, M., Klouche, K., Platon, L., Demoule, A., Mayaux, J., Wallet, F., Chermak, A., Lemaitre, C., Artaud-Macari, E., Nelsen, J., Spoelstra de Man, A. & for the Efraim investigators and the Nine-I study group, 1 Dec 2017, In : Intensive Care Medicine. 43, 12, p. 1808-1819 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Carbapenemresistente bacteriën overgebracht naar Nederland

Hoogewerf, M., Budding, A. E., Spoelstra-de Man, A. M. E., Vloemans, J. & Rozemeijer, W., 2017, In : Nederlands Tijdschrift voor Geneeskunde. 161, p. D1124

Research output: Contribution to journalReview articleAcademicpeer-review

Carbapenemresistente bacteriën overgebracht naar Nederland, Patiënten gekoloniseerd tijdens ziekenhuis opname in Roemenie

Hoogewerf, M., Budding, A. E., Spoelstra-De Man, A. M. E., Vloemans, J. & Rozemeijer, W., 2017, In : Nederlands Tijdschrift voor Geneeskunde. 161, 16, d1124.

Research output: Contribution to journalArticleProfessional

Different effects of fluid loading with saline, gelatine, hydroxyethyl starch or albumin solutions on acid-base status in the critically ill

Spoelstra-de Ma, A. M. E., Smorenberg, A. & Groeneveld, A. B. J., 1 Apr 2017, In : PLoS ONE. 12, 4, e0174507.

Research output: Contribution to journalArticleAcademicpeer-review

How to Give Vitamin C a Cautious but Fair Chance in Severe Sepsis

Oudemans-van Straaten, H. M., Elbers, P. W. G. & Spoelstra-de Man, A. M. E., 1 Jun 2017, In : Chest. 151, 6, p. 1199-1200 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Hyperoxia: At what level of SpO2 is a patient safe? A study in mechanically ventilated ICU patients

Durlinger, E. M. J., Spoelstra-de Man, A. M. E., Smit, B., de Grooth, H. J., Girbes, A. R. J., Oudemans-van Straaten, H. M. & Smulders, Y. M., 1 Jun 2017, In : Journal of Critical Care. 39, p. 199-204 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hyperoxia does not alter oxygen delivery in healthy volunteers

Smit, B., Smulders, Y. M., de Grooth, H. J., Gelissen, H. P. M. M., Girbes, A. R. J., Schotman, H. H. M., Scheffer, P. G., Oudemans-van Straaten, H. M. & Spoelstra-de Man, A. M. E., 2017, In : Intensive Care Medicine Experimental. 5(Suppl 2), 44, p. 254 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hyperoxia does not directly affect vascular tone in isolated arteries from mice

Smit, B., Smulders, Y. M., De Waard, M. C., Oudemans-Van Straaten, H. M., Girbes, A. R. J., Eringa, E. C. & Spoelstra - De Man, A. M. E., 1 Aug 2017, In : PLoS ONE. 12, 8, e0182637.

Research output: Contribution to journalArticleAcademicpeer-review

Low Transmission of Airway Pressures to the Abdomen in Mechanically Ventilated Patients with or Without Acute Respiratory Failure and Intra-Abdominal Hypertension

Heijnen, B. G. A. D. H., Spoelstra-De Man, A. M. E. & Groeneveld, A. B. J., 2017, In : Journal of Intensive Care Medicine. 32, 3, p. 218-222 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Oxygen supplementation among patients in the intensive care unit

Spoelstra-De Man, A. M. E., Oudemans-Van Straaten, H. M. & Girbes, A. R. J., 14 Feb 2017, In : JAMA - Journal of the American Medical Association. 317, 6, p. 646-647 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

Prevention or treatment of ARDS with aspirin: A review of preclinical models and meta-analysis of clinical studies

Panka, B. A., De Grooth, H. J., Spoelstra-De Man, A. M. E., Looney, M. & Tuinman, P. R., 1 Jan 2017, In : Shock. 47, 1, p. 13-21 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Response

Oudemans-van Straaten, H. M., Elbers, P. W. G. & Spoelstra-de Man, A. M. E., 1 Sep 2017, In : Chest. 152, 3, p. 687-688 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

Response to the letter to the editor

Durlinger, E. M. J., Spoelstra-de Man, A. M. E. & Smulders, Y. M., 1 Aug 2017, In : Journal of Critical Care. 40, p. 285 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

The effects of hyperoxia on microvascular endothelial cell proliferation and production of vaso-active substances

Attaye, I., Smulders, Y. M., de Waard, M. C., Oudemans-van Straaten, H. M., Smit, B., Van Wijhe, M. H., Musters, R. J., Koolwijk, P. & Spoelstra-de Man, A. M. E., Apr 2017, In : Intensive Care Medicine Experimental. 5, 1, 22.

Research output: Contribution to journalArticleAcademicpeer-review

Towards improved outcome after cardiac arrest: New studies coming up

Horn, J., Hofmeijer, J., Kuiper, M. & Spoelstra-de Man, A., 1 Nov 2017, In : Netherlands Journal of Critical Care. 25, 6, p. 222-226 5 p.

Research output: Contribution to journalLetterAcademicpeer-review

2016

Legal issues encountered in the intensive care: presentation of three cases

van Rijswijk, S., Broekman, K. & Spoelstra-de Man, A. M. E., Nov 2016, In : Netherlands Journal of Critical Care. 24, 7, p. 19-21

Research output: Contribution to journalArticleProfessional

2015

Cardiovascular effects of hyperoxia during and after cardiac surgery

de Man, A. M. E., Smit, B., van Straaten, H. M. & Smulders, Y. M., 2015, In : Anaesthesia. 70, 11, p. 1307-1319

Research output: Contribution to journalArticleAcademicpeer-review

De cardiovasculaire effecten van hyperoxie

Buiter, C. W. & Spoelstra-de Man, A. M. E., 2015, In : A&I. 2015, 3

Research output: Contribution to journalArticleProfessional

Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients

Hooijman, P. E., Beishuizen, A., Witt, C. C., de Waard, M. C., Girbes, A. R. J., Spoelstra-de Man, A. M. E., Niessen, H. W., Manders, E., van Hees, H. W. H., van den Brom, C. E., Silderhuis, V., Lawlor, M. W., Labeit, S., Stienen, G. J. M., Hartemink, K. J., Paul, M. A., Heunks, L. M. A. & Ottenheijm, C. A. C., 15 May 2015, In : American Journal of Respiratory and Critical Care Medicine. 191, 10, p. 1126-1138 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial

Straat, M., Mueller, M. C. A., Meijers, J. C. M., Arbous, M. S., Spoelstra-de Man, A. M. E., Beurskens, C. J. P., Vroom, M. B. & Juffermans, N. P., 2015, In : Critical Care. 19, 163.

Research output: Contribution to journalArticleAcademicpeer-review