Anne-Marie van Dam

DR., (Principal Investigator)

20002019
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Research Output 2000 2019

2019

Blood cell-derived human tissue Transglutaminase (TG2) in multiple sclerosis: -Implications for the pathogenesis and clinical outcome-

Sestito, C., 2019, 133 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Open Access

Differential insular cortex subregional vulnerability to α-synuclein pathology in Parkinson's disease and dementia with Lewy bodies

Fathy, Y. Y., Jonker, A. J., Oudejans, E., de Jong, F. J. J., van Dam, A. M. W., Rozemuller, A. J. M. & van de Berg, W. D. J., 1 Apr 2019, In : Neuropathology and Applied Neurobiology. 45, 3, p. 262-277 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Enhanced GABAergic immunoreactivity in hippocampal neurons and astroglia of multiple sclerosis patients

Kiljan, S., Prins, M., Baselmans, B. M., Bol, J. G. J. M., Schenk, G. J. & van Dam, A-M., 1 Jan 2019, In : Journal of Neuropathology and Experimental Neurology. 78, 6, p. 480-491

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Tissue transglutaminase promotes early differentiation of oligodendrocyte progenitor cells

Espitia Pinzon, N., van Mierlo, H., de Jonge, J. C., Brevé, J. J. P., Bol, J. G. J. M., Drukarch, B., van Dam, A-M. & Baron, W., 14 May 2019, In : Frontiers in Cellular Neuroscience. 13, 281.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018
Open Access

Correction: Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

Chrobok, N. L., Bol, J. G. J. M., Jongenelen, C. A., Brevé, J. J. P., El Alaoui, S., Fidalgo-Lopez, J., Fournet, G., Joseph, B., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A-M., 2018, In : PLoS ONE. 13, 12, p. e0209522

Research output: Contribution to journalArticleAcademicpeer-review

Galectin-4, a Negative Regulator of Oligodendrocyte Differentiation, Is Persistently Present in Axons and Microglia/Macrophages in Multiple Sclerosis Lesions

de Jong, C. G. H. M., Stancic, M., Pinxterhuis, T. H., van Horssen, J., van Dam, A-M., Gabius, H-J. & Baron, W., 2018, In : Journal of Neuropathology and Experimental Neurology. 77, 11, p. 1024-1038 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Much, if not all, of the cortical damage in MS can be attributed to the microglial cell – Yes

van Wageningen, T. A. & van Dam, A-M., 2018, In : Multiple Sclerosis Journal. 24, 7, p. 895-896

Research output: Contribution to journalComment/Letter to the editorAcademic

The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis

Hoeijmakers, L., Meerhoff, G. F., de Vries, J. W., Ruigrok, S. R., van Dam, A-M., van Leuven, F., Korosi, A. & Lucassen, P. J., Jan 2018, In : Neurobiology of Aging. 61, p. 112-123 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Transglutaminase 6 antibodies are not yet mainstream in neuro-coeliac disease

Mulder, C. J. J., Rouvroye, M. D. & van Dam, A-M., Jan 2018, In : Digestive and Liver Disease. 50, 1, p. 96-97 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination

Espitia Pinzon, N., Sanz-Morello, B., Brevé, J. J. P., Bol, J. G. J. M., Drukarch, B., Bauer, J., Baron, W. & Van Dam, A. M., 27 Jan 2017, In : Scientific Reports. 7, 40995.

Research output: Contribution to journalArticleAcademicpeer-review

Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy

Grace, P. M., Loram, L. C., Christianson, J. P., Strand, K. A., Flyer-Adams, J. G., Penzkover, K. R., Forsayeth, J. R., van Dam, A. M., Mahoney, M. J., Maier, S. F., Chavez, R. A. & Watkins, L. R., 1 Jan 2017, In : Brain, Behavior, and Immunity. 59, p. 49-54 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer's disease mouse model

Hoeijmakers, L., Ruigrok, S. R., Amelianchik, A., Ivan, D., van Dam, A. M., Lucassen, P. J. & Korosi, A., 1 Jul 2017, In : Brain, Behavior, and Immunity. 63, p. 160-175 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Is monocyte- and macrophage-derived tissue transglutaminase involved in inflammatory processes?

Chrobok, N. L., Sestito, C., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A. M., 1 Mar 2017, In : Amino Acids. 49, 3, p. 441-452 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Monocyte behaviour and tissue transglutaminase expression during experimental autoimmune encephalomyelitis in transgenic CX3CR1gfp/gfp mice

Chrobok, N. L., Jaouen, A., Fenrich, K. K., Bol, J. G. J. M., Wilhelmus, M. M. M., Drukarch, B., Debarbieux, F. & van Dam, A. M., 1 Mar 2017, In : Amino Acids. 49, 3, p. 643-658 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?

Sestito, C., Brevé, J. J. P., van Eggermond, M. C. J. A., Killestein, J., Teunissen, C. E., van Rossum, J., Wilhelmus, M. M. M., Drukarch, B., van den Elsen, P. J. & van Dam, A-M., 21 Dec 2017, In : Journal of Neuroinflammation. 14, 1, p. 257

Research output: Contribution to journalArticleAcademicpeer-review

2016

Chronic retinoic acid treatment suppresses adult hippocampal neurogenesis, in close correlation with depressive-like behavior

Hu, P., Wang, Y., Liu, J., Meng, F-T., Qi, X-R., Chen, L., van Dam, A-M., Joëls, M., Lucassen, P. J. & Zhou, J-N., Jul 2016, In : Hippocampus. 26, 7, p. 911-23 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?

Hoeijmakers, L., Heinen, Y., van Dam, A-M., Lucassen, P. J. & Korosi, A., 9 Aug 2016, In : Frontiers in Human Neuroscience. 10, p. 398

Research output: Contribution to journalReview articleAcademicpeer-review

83 Downloads (Pure)

Neuronal and glial changes in white and grey matter of Multiple Sclerosis patients

Prins, M., 2016

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File
2015

Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats

Loram, L. C., Strand, K. A., Taylor, F. R., Sloane, E., Van Dam, A-M., Rieger, J., Maier, S. F. & Watkins, L. R., May 2015, In : Brain Behavior and Immunity. 46, p. 50-54 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Brain region-specific gene expression profiles in freshly isolated rat microglia

Doorn, K. J., Brevé, J. J. P., Drukarch, B., Boddeke, H. W., Huitinga, I., Lucassen, P. J. & van Dam, A-M., 2015, In : Frontiers in Cellular Neuroscience. 9, p. 84

Research output: Contribution to journalArticleAcademicpeer-review

Brain Region-Specific Microglial Phenotypes and Responses in Parkinson’s Disease

Doorn, K. J., 2015

Research output: ThesisResearch VU University Amsterdam, graduation externalAcademic

Pathological differences between white and grey matter multiple sclerosis lesions

Prins, M., Schul, E., Geurts, J., van der Valk, P., Drukarch, B. & van Dam, A-M., Sep 2015, In : Annals of the New York Academy of Sciences. 1351, p. 99-113 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation

Lucassen, P. J., Oomen, C. A., Naninck, E. F. G., Fitzsimons, C. P., van Dam, A-M., Czeh, B. & Korosi, A., 1 Sep 2015, In : Cold Spring Harbor Perspectives in Biology. 7, 9, p. a021303

Research output: Contribution to journalReview articleAcademicpeer-review

Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration

van Strien, M. E., de Vries, H. E., Chrobok, N. L., Bol, J. G. J. M., Breve, J. J. P., van der Pol, S. M. P., Kooij, G., van Buul, J. D., Karpuj, M., Steinman, L., Wilhelmus, M. M., Sestito, C., Drukarch, B. & Van Dam, A-M., Nov 2015, In : Brain Behavior and Immunity. 50, p. 141-154 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014

Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients

Prins, M., Dutta, R., Baselmans, B., Brevé, J. J. P., Bol, J. G. J. M., Deckard, S. A., van der Valk, P., Amor, S., Trapp, B. D., de Vries, H. E., Drukarch, B. & van Dam, A-M., 23 Aug 2014, In : Acta Neuropathologica Communinications. 2, p. 98

Research output: Contribution to journalArticleAcademicpeer-review

Hippocampal proliferation is increased in presymptomatic Parkinson's disease and due to microglia

Doorn, K. J., Drukarch, B., van Dam, A-M. & Lucassen, P. J., 2014, In : Neural Plasticity. 2014, p. 959154

Research output: Contribution to journalArticleAcademicpeer-review

Increased amoeboid microglial density in the olfactory bulb of Parkinson's and Alzheimer's patients

Doorn, K. J., Goudriaan, A., Blits-Huizinga, C., Bol, J. G. J. M., Rozemuller, A. J., Hoogland, P. V. J. M., Lucassen, P. J., Drukarch, B., van de Berg, W. D. J. & van Dam, A-M., Mar 2014, In : Brain Pathology. 24, 2, p. 152-65 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuropathology of stress

Lucassen, P. J., Pruessner, J., Sousa, N., Almeida, O. F. X., Van Dam, A. M., Rajkowska, G., Swaab, D. F. & Czéh, B., Jan 2014, In : Acta Neuropathologica. 127, 1, p. 109-135 27 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models

Schuh, C., Wimmer, I., Hametner, S., Haider, L., Van Dam, A-M., Liblau, R. S., Smith, K. J., Probert, L., Binder, C. J., Bauer, J., Bradl, M., Mahad, D. & Lassmann, H., Aug 2014, In : Acta Neuropathologica. 128, 2, p. 247-266 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

The novel target

van Dam, A. M. W., 2014, In : International Innovation. 162, p. 13-15

Research output: Contribution to journalArticlePopular

Tissue transglutaminase in marmoset experimental multiple sclerosis: discrepancy between white and grey matter

Espitia Pinzon, N., Stroo, E., 't Hart, B. A., Bol, J. G. J. M., Drukarch, B., Bauer, J. & van Dam, A-M., 2014, In : PLoS ONE. 9, 6, p. e100574

Research output: Contribution to journalArticleAcademicpeer-review

2013

Interleukin-1β and interleukin-1 receptor antagonist appear in grey matter additionally to white matter lesions during experimental multiple sclerosis

Prins, M., Eriksson, C., Wierinckx, A., Bol, J. G. J. M., Binnekade, R., Tilders, F. J. H. & Van Dam, A-M., 2013, In : PLoS ONE. 8, 12, p. e83835 e83835.

Research output: Contribution to journalArticleAcademicpeer-review

2012
19 Downloads (Pure)

A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation

Hu, P., Oomen, C., van Dam, A-M., Wester, J., Zhou, J-N., Joëls, M. & Lucassen, P. J., 2012, In : PLoS ONE. 7, 9

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Emerging roles of microglial activation and non-motor symptoms in Parkinson's disease

Doorn, K. J., Lucassen, P. J., Boddeke, H. W., Prins, M., Berendse, H. W., Drukarch, B. & van Dam, A-M., 2012, In : Progress in Neurobiology. 98, 2, p. 222-238 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

2011

Appearance of tissue transglutaminase in astrocytes in multiple sclerosis lesions: a role in cell adhesion and migration?

van Strien, M. E., Drukarch, B., Bol, J. G., van der Valk, P., van Horssen, J., Gerritsen, W. H., Breve, J. J. & van Dam, A-M., 2011, In : Brain Pathology. 21, 1, p. 44-54 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Downloads (Pure)

Astrocyte-derived tissue transglutaminase interacts with fibronectin: a role in astrocyte adhesion and migration?

van Strien, M. E., Brevé, J. J. P., Fratantoni, S., Schreurs, M. W. J., Bol, J. G. J. M., Jongenelen, C. A. M., Drukarch, B. & van Dam, A-M., 2011, In : PLoS ONE. 6, 9

Research output: Contribution to journalArticleAcademicpeer-review

File

Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease

Verhaar, R., Jongenelen, C. A. M., Gerard, M., Baekelandt, V., Van Dam, A-M., Wilhelmus, M. M. M. & Drukarch, B., Jun 2011, In : Neurochemistry International. 58, 7, p. 785-793 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

49 Downloads (Pure)

Cholinergic imbalance in the multiple sclerosis hippocampus

Kooi, E-J., Prins, M., Bajic, N., Beliën, J. A. M., Gerritsen, W. H., van Horssen, J., Aronica, E., van Dam, A-M., Hoozemans, J. J. M., Francis, P. T., van der Valk, P. & Geurts, J. J. G., Sep 2011, In : Acta Neuropathologica. 122, 3, p. 313-322 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

Linker, R. A., Lee, D-H., Ryan, S., van Dam, A. M., Conrad, R., Bista, P., Zeng, W., Hronowsky, X., Buko, A., Chollate, S., Ellrichmann, G., Brück, W., Dawson, K., Goelz, S., Wiese, S., Scannevin, R. H., Lukashev, M. & Gold, R., Mar 2011, In : Brain. 134, Pt 3, p. 678-692 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Novel role of transglutaminase 1 in corpora amylacea formation?

Wilhelmus, M. M. M., Verhaar, R., Bol, J. G. J. M., van Dam, A-M., Hoozemans, J. J. M., Rozemuller, A. J. M. & Drukarch, B., 2011, In : Neurobiology of Aging. 32, 5, p. 845-856 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

40 Downloads (Pure)

Tissue Transglutaminase: a multifoaceted therapeutic target for Multiple Sclerosis

van Strien, M. E., 2011

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin-forming oligodendrocytes during CNS remyelination

Van Strien, M. E., Baron, W., Bakker, E. N. T. P., Bauer, J., Bol, J. G. J. M., Brevé, J. J. P., Binnekade, R., Van Der Laarse, W. J., Drukarch, B. & Van Dam, A-M., Nov 2011, In : GLIA. 59, 11, p. 1622-1634 13 p.

Research output: Contribution to journalArticleAcademicpeer-review