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Personal profile

Research interests

Ylstra received a bachelors in Physics in 1988 from the University of Amsterdam (UvA, NL) and commenced with a masters in Genetics at the Vrije Universiteit (VU, NL). In 1995 he received his PhD degree from the same university for work performed at the Universities of Vienna (A) and Nijmegen (NL), Plant Research International (NL) and The John Innes Institute (UK). He was awarded a 2-year NATO fellowship for his post-doctoral work at the University of California in Berkeley (USA) on genome-wide RNA screens . From 1998 he worked at the Comprehensive Cancer Center of the University of California, San Francisco (USA) and was involved in the development of DNA arrays for copy number analysis. In 2001 he accepted his current position at the VU University Medical Center, Cancer Center Amsterdam heading the Tumor Genome Analysis Core. The core has a strong genome laboratory and bioinformatics (pre-)processing track record, with an emphasis on DNA analysis from archival material, see more under http://www.tgac.nl.

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Research Output 2001 2019

Aggressive genomic features in clinically indolent primary HHV8-negative effusion-based lymphoma

Mendeville, M., Roemer, M. G. M., van den Hout, M. F. C. M., Los-de Vries, G. T., Bladergroen, R., Stathi, P., Hijmering, N. J., Rosenwald, A., Ylstra, B. & de Jong, D., 24 Jan 2019, In : Blood. 133, 4, p. 377-380 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Colorectal metastasis to the gallbladder mimicking a primary gallbladder malignancy: histopathological and molecular characteristics

de Bitter, T. J. J., van der Linden, R. L. A., van Vliet, S., Weren, F., Sie, D., Ylstra, B., van der Linden, H. C., Knijn, N., Ligtenberg, M. J. L., van der Post, R. S., Simmer, F. & Nagtegaal, I. D., 2 May 2019, In : Histopathology.

Research output: Contribution to journalArticleAcademicpeer-review

Establishment and Genetic Landscape of Precancer Cell Model Systems from the Head and Neck Mucosal Lining

de Boer, D. V., Brink, A., Buijze, M., Stigter-van Walsum, M., Hunter, K. D., Ylstra, B., Bloemena, E., Leemans, C. R. & Brakenhoff, R. H., Jan 2019, In : Molecular Cancer Research. 17, 1, p. 120-130 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts

van der Heijden, M., Miedema, D. M., Waclaw, B., Veenstra, V. L., Lecca, M. C., Nijman, L. E., van Dijk, E., van Neerven, S. M., Lodestijn, S. C., Lenos, K. J., de Groot, N. E., Prasetyanti, P. R., Varea, A. A., Winton, D. J., Medema, J. P., Morrissey, E., Ylstra, B., Nowak, M. A., Bijlsma, M. F. & Vermeulen, L., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6140-6145

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

ACE: Absolute Copy number Estimation from low-coverage whole-genome sequencing data

Poell, J. B., Mendeville, M., Sie, D., Brink, A., Brakenhoff, R. H. & Ylstra, B., 28 Dec 2018, In : Bioinformatics.

Research output: Contribution to journalArticleAcademicpeer-review