19972018
If you made any changes in Pure these will be visible here soon.

Research Output 1997 2018

  • 30 Article
  • 3 Review article
  • 2 Chapter
  • 2 Research VU University Amsterdam, graduation VU University Amsterdam
2018

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2

Decout, A., Silva-Gomes, S., Drocourt, D., Blattes, E., Rivière, M., Prandi, J., Larrouy-Maumus, G. R., Caminade, A-M., Hamasur, B., Källenius, G., Kaur, D., Dobos, K. M., Lucas, M., Sutcliffe, I. C., Besra, G. S., Appelmelk, B. J., Gilleron, M., Jackson, M., Vercellone, A., Tiraby, G. R. & 1 othersNigou, J. R., 2018, In : Scientific Reports. 8, 1, 16840.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria

van de Weerd, R., Boot, M., Maaskant, J., Sparrius, M., Verboom, T., van Leeuwen, L. M., Burggraaf, M. J., Paauw, N. J., Dainese, E., Manganelli, R., Bitter, W., Appelmelk, B. J. & Geurtsen, J., 27 May 2016, In : Journal of Biological Chemistry. 291, 22, p. 11787-11799

Research output: Contribution to journalArticleAcademicpeer-review

Metabolic Network for the Biosynthesis of Intra- and Extracellular alpha-Glucans Required for Virulence of Mycobacterium tuberculosis

Koliwer-Brandl, H., Syson, K., van de Weerd, R., Chandra, G., Appelmelk, B., Alber, M., Ioerger, T. R., Jacobs, W. R. . J., Geurtsen, J., Bornemann, S. & Kalscheuer, R., Aug 2016, In : PLoS Pathogens. 12, 8

Research output: Contribution to journalArticleAcademicpeer-review

28 Downloads (Pure)

Mysteries beyond the mycomembrane: insights into capsular a-glucan biogenesis

van de Weerd, R., 2016

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File
2015

A Murine Monoclonal Antibody to Glycogen: Characterization of Epitope-Fine Specificity by Saturation Transfer Difference (STD) NMR Spectroscopy and Its Use in Mycobacterial Capsular alpha-Glucan Research

van de Weerd, R., Berbis, M. A., Sparrius, M., Maaskant, J. J., Boot, M., Paauw, N. J., de Vries, N., Boon, L., Baba, O., Canada, F. J., Geurtsen, J. J. G., Jimenez-Barbero, J. & Appelmelk, B. J., 2015, In : ChemBioChem. 16, 6, p. 977-989

Research output: Contribution to journalArticleAcademicpeer-review

Human milk blocks DC-SIGN-pathogen interaction via MUC1

Koning, N., Kessen, S. F. M., van der Voorn, J. P., Appelmelk, B. J., Jeurink, P. V., Knippels, L. M. J., Garssen, J. & van Kooyk, Y., 2015, In : Frontiers in Immunology: Molecular Innate Immunity. 6, 112.

Research output: Contribution to journalArticleAcademicpeer-review

2014

Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo

Romano, M., van de Weerd, R., Brouwer, F. C. C., Roviello, G. N., Lacroix, R., Sparrius, M., van Stempvoort, G., Appelmelk, B. J., Geurtsen, J. J. G. & Berisio, R., 2014, In : Structure. 22, 5, p. 719-730

Research output: Contribution to journalArticleAcademicpeer-review

2013

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

Afonso-Barroso, A., Clark, S. O., Williams, A., Rosa, G. T., Nobrega, C., Silva-Gomes, S., Vale-Costa, S., Ummels, R., Stoker, N., Movahedzadeh, F., van der Ley, P., Sloots, A., Cot, M., Appelmelk, B. J., Puzo, G., Nigou, J., Geurtsen, J. J. G. & Appelberg, R., 2013, In : Cellular Microbiology. 15, 4, p. 660-674

Research output: Contribution to journalArticleAcademicpeer-review

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

Stoop, E. J. M., Mishra, A. K., Driessen, N. N., van Stempvoort, G., Bouchier, P., Verboom, T., van Leeuwen, L. M., Sparrius, M., Raadsen, S. A., van Zon, M., van der Wel, N. N., Besra, G. S., Geurtsen, J. J. G., Bitter, W., Appelmelk, B. J. & van der Sar, A. M., 2013, In : Cellular Microbiology. 15, 12, p. 2093-2108

Research output: Contribution to journalArticleAcademicpeer-review

2012

Cyanovirin-N Inhibits Mannose-Dependent Mycobacterium-C-Type Lectin Interactions but Does Not Protect against Murine Tuberculosis

Driessen, N. N., Boshoff, H. I. M., Maaskant, J. J., Gilissen, S. A. C., Vink, S., van der Sar, A. M., Vandenbroucke-Grauls, C. M. J. E., Bewley, C. A., Appelmelk, B. J. & Geurtsen, J. J. G., 2012, In : Journal of Immunology. 189, 7, p. 3585-3592

Research output: Contribution to journalArticleAcademicpeer-review

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish.

Weerdenburg, E. M., Abdallah, A. M., Mitra, S., de Punder, K., van der Wel, N. N., Bird, S., Appelmelk, B. J., Bitter, W. & van der Sar, A. M., 2012, In : Cellular Microbiology. 14, 5, p. 728-739

Research output: Contribution to journalArticleAcademicpeer-review

2011
34 Downloads (Pure)

Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity

Chang, Y. J., Kim, H. Y., Albacker, L. A., Lee, H. H., Baumgarth, N., Akira, S., Savage, P. B., Endo, S., Yamamura, T., Maaskant, J., Kitano, N., Singh, A., Bhatt, A., Besra, G. S., van den Elzen, P., Appelmelk, B. J., Franck, R. W., Chen, G. W., DeKruyff, R. H., Shimamura, M. & 2 othersIllarionov, P. & Umetsu, D. T., 2011, In : Journal of Clinical Investigation. 121, 1, p. 57-69

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Interaction of surface glycans of Mycobacterium tuberculosis with DC-SIGN

Appelmelk, B. J., Driessen, N. N., Geurtsen, J. J. G. & Vandenbroucke-Grauls, C. M. J. E., 2011, Glycosylation in diverse cell systems. London: Society of Experimental Biology, p. 1

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interaction

Mishra, A. K., Driessen, N. N., Appelmelk, B. J. & Besra, G. S., 2011, In : Fems Microbiology Reviews. 35, 6, p. 1126-1157

Research output: Contribution to journalArticleAcademicpeer-review

Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two alpha(1 -> 2)-mannopyranosyltransferases MptC and MptD in mannan branching

Mishra, A. K., Krumbach, K., Rittmann, D., Appelmelk, B. J., Pathak, V., Pathak, A. K., Nigou, J., Geurtsen, J. J. G., Eggeling, L. & Besra, G. S., 2011, In : Molecular Microbiology. 80, 5, p. 1241-1259

Research output: Contribution to journalArticleAcademicpeer-review

24 Downloads (Pure)

Sugar caps of mycobacteria: virulence factors or decorative elements?

Driessen, N. N., 2011

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File
2010

A truncated lipoglycan from mycobacteria with altered immunological properties

Birch, H. L., Alderwick, L. J., Appelmelk, B. J., Maaskant, J. J., Bhatt, A., Singh, A., Nigou, J., Eggeling, L., Geurtsen, J. J. G. & Besra, G. S., 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 6, p. 2634-2639

Research output: Contribution to journalArticleAcademicpeer-review

29 Downloads (Pure)

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins.

Sani, M., Houben, E. N. G., Geurtsen, J. J. G., Pierson, J., de Punder, K., van Zon, M., Wever, B., Piersma, S. R., Jimenez, C. R., Daffe, M., Appelmelk, B. J., Bitter, W., Wel, N. & Peters, P. J., 2010, In : PLoS Pathogens. 6, 3, p. e1000794 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Mycobacterium marinum MMAR_2380, a predicted transmembrane acyltransferase, is essential for the presence of the mannose cap on lipoarabinomannan

Driessen, N. N., Stoop, E. J. M., Ummels, R., Gurcha, S. S., Mishra, A. K., Larrouy-Maumus, G., Nigou, J., Gilleron, M., Puzo, G., Maaskant, J. J., Sparrius, M., Besra, G. S., Bitter, W., Vandenbroucke-Grauls, C. M. J. E. & Appelmelk, B. J., 2010, In : Microbiology. 156, p. 3492-3502

Research output: Contribution to journalArticleAcademicpeer-review

2009

Identification of Mycobacterial alpha-Glucan As a Novel Ligand for DC-SIGN: Involvement of Mycobacterial Capsular Polysaccharides in Host Immune Modulation

Geurtsen, J. J. G., Chedammi, S., Mesters, J., Cot, M., Driessen, N. N., Sambou, T., Kakutani, R., Ummels, R., Maaskant, J. J., Takata, H., Baba, O., Terashima, T., Bovin, N., Vandenbroucke-Grauls, C. M. J. E., Nigou, J., Puzo, G., Lemassu, A., Daffe, M. & Appelmelk, B. J., 2009, In : Journal of Immunology. 183, 8, p. 5221-5231

Research output: Contribution to journalArticleAcademicpeer-review

Mannose-fucose recognition by DC-SIGN

Geurtsen, J. J. G., Driessen, N. N. & Appelmelk, B. J., 2009, Microbial Glycobiology. Ac Press

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5

Abdallah, A. M., Verboom, T., Weerdenburg, E. M., van Pittius, N. C. G., Mahasha, P. W., Jimenez, C. R., Parra, M., Cadieux, N., Brennan, M. J., Appelmelk, B. J. & Bitter, W., 2009, In : Molecular Microbiology. 73, 3, p. 329-340

Research output: Contribution to journalArticleAcademicpeer-review

29 Downloads (Pure)

Role of Phosphatidylinositol Mannosides in the Interaction between Mycobacteria and DC-SIGN

Driessen, N. N., Ummels, R., Maaskant, J. J., Gurcha, S. S., Besra, G. S., Ainge, G. D., Larsen, D. S., Painter, G. F., Vandenbroucke-Grauls, C. M. J. E., Geurtsen, J. J. G. & Appelmelk, B. J., 2009, In : Infection and Immunity. 77, 10, p. 4538-4547

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Type VII secretion in mycobacteria: classification in line with cell envelope structure.

Bitter, W., Houben, E. N. G., Luirink, S. & Appelmelk, B. J., 2009, In : Trends In Microbiology. 8, p. 337-338

Research output: Contribution to journalArticleAcademicpeer-review

2008

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens

Dunlop, D. C., Ulrich, A., Appelmelk, B. J., Burton, D. R., Dwek, R. A., Zitzmann, N. & Scanlan, C. N., 2008, In : AIDS. 22, 16, p. 2214-2217

Research output: Contribution to journalArticleAcademicpeer-review

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction

Appelmelk, B. J., den Dunnen, J. T., Driessen, N. N., Ummels, R., Pak, M., Nigou, J., Larrouy-Maumus, G., Gurcha, S. S., Movahedzadeh, F., Geurtsen, J., Brown, E. J., Eysink Smeets, M. M., Besra, G. S., Willemsen, P. T., Lowary, T. L., van Kooyk, Y., Maaskant, J. J., Stoker, N. G., van der Ley, P., Puzo, G. & 6 othersVandenbroucke-Grauls, C. M. J. E., Wieland, C. W., van der Poll, T., Geijtenbeek, T. B. H., van der Sar, A. M. & Bitter, W., 2008, In : Cellular Microbiology. 10, 4, p. 930-944

Research output: Contribution to journalArticleAcademicpeer-review

2006

Helicobacter pylori phase variation, immune modulation and gastric autoimmunity

Bergman, M., Del Prete, G., van Kooyk, Y. & Appelmelk, B., Feb 2006, In : Critical Reviews in Microbiology. 4, 2, p. 151-9 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2005
13 Downloads (Pure)

Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells

van Vliet, S. J., van Liempt, E., Saeland, E., Aarnoudse, C. A., Appelmelk, B., Irimura, T., Geijtenbeek, T. B. H., Blixt, O., Alvarez, R., van Die, I. & van Kooyk, Y., May 2005, In : International Immunology. 17, 5, p. 661-669 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Carbohydrate specificities of the murine DC-SIGN homologue mSIGNR1

Koppel, E. A., Ludwig, I. S., Appelmelk, B. J., van Kooyk, Y. & Geijtenbeek, T. B. H., 2005, In : Immunobiology. 210, 2-4, p. 195-201 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2004

Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN

Bergman, M. P., Engering, A., Smits, H. H., van Vliet, S. J., van Bodegraven, A. A., Wirth, H-P., Kapsenberg, M. L., Vandenbroucke-Grauls, C. M. J. E., van Kooyk, Y. & Appelmelk, B. J., 18 Oct 2004, In : Journal of Experimental Medicine. 200, 8, p. 979-90 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1

Koppel, E. A., Ludwig, I. S., Hernandez, M. S., Lowary, T. L., Gadikota, R. R., Tuzikov, A. B., Vandenbroucke-Grauls, C. M. J. E., van Kooyk, Y., Appelmelk, B. J. & Geijtenbeek, T. B. H., 2004, In : Immunobiology. 209, 1-2, p. 117-27 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2003

A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance

van Kooyk, Y., Appelmelk, B. & Geijtenbeek, T. B. H., Apr 2003, In : Trends in Molecular Medicine. 9, 4, p. 153-9 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Mycobacteria target DC-SIGN to suppress dendritic cell function

Geijtenbeek, T. B. H., Van Vliet, S. J., Koppel, E. A., Sanchez-Hernandez, M., Vandenbroucke-Grauls, C. M. J. E., Appelmelk, B. & Van Kooyk, Y., 6 Jan 2003, In : Journal of Experimental Medicine. 197, 1, p. 7-17 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Downloads (Pure)

The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x

van Die, I., van Vliet, S. J., Nyame, A. K., Cummings, R. D., Bank, C. M. C., Appelmelk, B., Geijtenbeek, T. B. H. & van Kooyk, Y., Jun 2003, In : Glycobiology. 13, 6, p. 471-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2001

Adjuvante behandelingen voor sepsis en shock: Welke zijn effectief?

Groeneveld, A. B. J., Beishuizen, A., Appelmelk, B. J. & Girbes, A. R. J., 8 Sep 2001, In : Nederlands Tijdschrift voor Geneeskunde. 145, 36, p. 1718-1722 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

1997

A monoclonal antibody directed against high M(r) salivary mucins recognizes the SO3-3Gal beta 1-3GlcNAc moiety of sulfo-Lewis(a): a histochemical survey of human and rat tissue

Veerman, E. C., Bolscher, J. G., Appelmelk, B. J., Bloemena, E., van den Berg, T. K. & Nieuw Amerongen, A. V., Feb 1997, In : Glycobiology. 7, 1, p. 37-43 7 p.

Research output: Contribution to journalArticleAcademicpeer-review