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Personal profile

Research interests

Brenda Penninx, PhD, is professor of psychiatric epidemiology at the department of Psychiatry of Amsterdam UMC (location VUmc) in Amsterdam (https://psychiatryamsterdam.nl). Since 2004 she leads the Netherlands Study of Depression and Anxiety (NESDA: www.nesda.nl), a longitudinal study of the course and consequences of depressive and anxiety disorders. Prof. Penninx is currently also involved in several other (national and EU-funded) mental health cohort and intervention studies. Central themes in her research are understanding psychosocial, somatic and neurobiological risk factors and consequences of depression and anxiety disorders and how to impact on these to improve mental health. 

External positions

Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Wake Forest University School OfMedicine, Winston-Salem, NC, United States

20002003

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1994 2020

A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., A. C. ’t Hoen, P., van Meurs, J., Brooks, A. I., Boomsma, D. I., Penninx, B. W. J. H. & BIOS Consortium, Feb 2020, In : European Journal of Human Genetics. 28, 2, p. 253-263

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 206 othersAgerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Howard, D. M., Ising, M., Jansen, R., Jones, I., Jones, L. A., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M., O’Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C., Breen, G. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 2020, In : Nature Communications. 11, 1, 39.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Performance of methods to conduct mediation analysis with time-to-event outcomes

Burgos Ochoa, L., Rijnhart, J. J. M., Penninx, B. W., Wardenaar, K. J., Twisk, J. W. R. & Heymans, M. W., 1 Feb 2020, In : Statistica Neerlandica. 74, 1, p. 72-91 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Activities 2000 2019

Precision Medicine in Depression: Hype or hope?

Brenda Penninx (Invited speaker)
15 Jan 2019

Activity: Talk or presentationInvited talk

Towards personalizing depression treatment.

Brenda Penninx (Speaker)
1 Jul 2019

Activity: Talk or presentationInvited talk

Towards reducing the public health impact of anxiety disorders.

Brenda Penninx (Speaker)
5 Oct 2019

Activity: Talk or presentationInvited talk

Social stress induced psychopathologies.

Brenda Penninx (Speaker)
8 May 2019

Activity: Talk or presentationInvited talk

Press / Media

Waarom afvallen zo moeilijk is.

Brenda Penninx

11/05/2019

1 media contribution

Press/Media: Expert Comment

KennisCafé: Depressie Dossier.

Brenda Penninx & Christiaan Vinkers

27/11/2018

1 item of media coverage

Press/Media: Research

Introduction video Brenda Penninx

Brenda Penninx

01/06/2018

1 media contribution

Press/Media: Research

Brenda Penninx: puzzling over depression

Brenda Penninx

10/07/2017

1 item of media coverage

Press/Media: Interview

Amersfoortse hoogleraar bestrijdt volksziekte nr. 1: depressie

Brenda Penninx

31/07/2016

1 media contribution

Press/Media: Interview