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Research Output 1994 2019

2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Lifelines Cohort Study & V. A. Million Veteran Program, 2019, In : Nature Genetics. 51, 6, p. 957-972

Research output: Contribution to journalArticleAcademicpeer-review

Accelerating research on biological aging and mental health: Current challenges and future directions

Han, L. K. M., Verhoeven, J. E., Tyrka, A. R., Penninx, B. W. J. H., Wolkowitz, O. M., Månsson, K. N. T., Lindqvist, D., Boks, M. P., Révész, D., Mellon, S. H. & Picard, M., 1 Aug 2019, In : Psychoneuroendocrinology. 106, p. 293-311 19 p.

Research output: Contribution to journalReview articleAcademicpeer-review

A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

BIOS Consortium, 2019, In : European Journal of Human Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

Aligning the many definitions of treatment resistance in anxiety disorders: A systematic review

Bokma, W. A., Wetzer, G. A. A. M., Gehrels, J. B., Penninx, B. W. J. H., Batelaan, N. M. & van Balkom, A. L. J. M., 2019, In : Depression and Anxiety.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

A methylation study of long-term depression risk

Clark, S. L., Hattab, M. W., Chan, R. F., Shabalin, A. A., Han, L. K. M., Zhao, M., Smit, J. H., Jansen, R., Milaneschi, Y., Xie, L. Y., van Grootheest, G., Penninx, B. W. J. H., Aberg, K. A. & van den Oord, E. J. C. G., 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Anxiety sensitivity, its stability and longitudinal association with severity of anxiety symptoms

Hovenkamp-Hermelink, J. H. M., van der Veen, D. C., Oude Voshaar, R. C., Batelaan, N. M., Penninx, B. W. J. H., Jeronimus, B. F., Schoevers, R. A. & Riese, H., 2019, In : Scientific Reports. 9, 1, 4314.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

The EAGLE-ADHD Consortium, 2019, In : Behavior Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

Milaneschi, Y., Peyrot, W. J., Nivard, M. G., Mbarek, H., Boomsma, D. I. & W.J.H. Penninx, B., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 219.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of a priori dietary patterns with depressive symptoms: A harmonised meta-analysis of observational studies

on behalf of the MooDFOOD consortium, 1 Jan 2019, In : Psychological Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Association of food groups with depression and anxiety disorders

Gibson-Smith, D., Bot, M., Brouwer, I. A., Visser, M., Giltay, E. J. & Penninx, B. W. J. H., 2019, In : European Journal of Nutrition.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research team, 1 Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Associations of depressive symptoms and history with three a priori diet quality indices in middle-aged and older adults

Elstgeest, L. E. M., Winkens, L. H. H., Penninx, B. W. J. H., Brouwer, I. A. & Visser, M., 15 Apr 2019, In : Journal of Affective Disorders. 249, p. 394-403 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bidirectional associations between food groups and depressive symptoms: longitudinal findings from the Invecchiare in Chianti (InCHIANTI) study

Elstgeest, L. E. M., Visser, M., Penninx, B. W. J. H., Colpo, M., Bandinelli, S. & Brouwer, I. A., Feb 2019, In : British Journal of Nutrition. 121, 4, p. 439-450 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Body mass index in obsessive-compulsive disorder

Abramovitch, A., Anholt, G. E., Cooperman, A., van Balkom, A. J. L. M., Giltay, E. J., Penninx, B. W. & van Oppen, P., 2019, In : Journal of Affective Disorders. 245, p. 145-151

Research output: Contribution to journalArticleAcademicpeer-review

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

Han, L. KM., Dinga, R., Hahn, T., Ching, C., Eyler, L., Aftanas, L., Aghajani, M., Aleman, A., Baune, B., Berger, K., Brak, I., Filho, G. B., Carballedo, A., Connolly, C., Couvy-Duchesne, B., Cullen, K., Dannlowski, U., Davey, C., Dima, D., Duran, F. & 126 othersEnneking, V., Filimonova, E., Frenzel, S., Frodl, T., Fu, C., Godlewska, B., Gotlib, I., Grabe, H., Groenewold, N., Grotegerd, D., Gruber, O., Hall, G., Harrison, B., Hatton, S., Hermesdorf, M., Hickie, I., Ho, T., Hosten, N., Jansen, A., Kahler, C., Kircher, T., Klimes-Dougan, B., Kramer, B., Krug, A., Lagopoulos, J., Leenings, R., MacMaster, F., MacQueen, G., McIntosh, A., McLellan, Q., McMahon, K., Medland, S., Mueller, B., Mwangi, B., Osipov, E., Portella, M., Pozzi, E., Reneman, L., Repple, J., Rosa, P., Sacchet, M., Saemann, P., Schnell, K., Schrantee, A., Simulionyte, E., Soares, J., Sommer, J., Stein, D., Steinstrater, O., Strike, L., Thomopoulos, S., Tol, M-J. V., Veer, I., Vermeiren, R., Walter, H., Wee, N. V. D., Werff, S. V. D., Whalley, H., Winter, N., Wittfeld, K., Wright, M., Wu, M-J., Volzke, H., Yang, T., Zannias, V., Zubicaray, G. D., Zunta-Soares, G., Abe, C., Alda, M., Andreassen, O., Boen, E., Bonnin, C., Canales-Rodriguez, E., Cannon, D., Caseras, X., Chaim-Avancini, T., Elvsashagen, T., Favre, P., Foley, S., Fullerton, J., Goikolea, J., Haarman, B., Hajek, T., Henry, C., Houenou, J., Howells, F., Ingvar, M., Kuplicki, R., Lafer, B., Landen, M., Machado-Vieira, R., Malt, U., McDonald, C., Mitchell, P., Nabulsi, L., Otaduy, M., Overs, B., Polosan, M., Pomarol-Clotet, E., Radua, J., Rive, M., Roberts, G., Ruhe, H., Salvador, R., Sarro, S., Satterthwaite, T., Savitz, J., Schene, A., Schofield, P., Serpa, M., Sim, K., Soeiro-de-Souza, M., Sutherland, A., Temmingh, H., Timmons, G., Uhlmann, A., Vieta, E., Wolf, D., Zanetti, M., Jahanshad, N., Thompson, P., Veltman, D., Penninx, B., Marquand, A., Cole, J. & Schmaal, L., 2019, In : Biorxiv. p. 560623

Research output: Contribution to journalArticleAcademic

Can chronotype function as predictor of a persistent course of depressive and anxiety disorder?

Druiven, S. J. M., Knapen, S. E., Penninx, B. W. J. H., Antypa, N., Schoevers, R. A., Riese, H. & Meesters, Y., 2019, In : Journal of Affective Disorders. 242, p. 159-164

Research output: Contribution to journalArticleAcademicpeer-review

Childhood maltreatment, vulnerability characteristics and adult incident common mental disorders: 3-year longitudinal data among >10,000 adults in the general population

ten Have, M., de Graaf, R., van Dorsselaer, S., Tuithof, M., Kleinjan, M. & Penninx, B. W. J. H., 2019, In : Journal of Psychiatric Research. 113, p. 199-207

Research output: Contribution to journalArticleAcademicpeer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2019, In : Biological Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comparing factor structures of depressed patients with and without suicidal ideation, a measurement invariance analysis

van Ballegooijen, W., Eikelenboom, M., Fokkema, M., Riper, H., van Hemert, A. M., Kerkhof, A. J. F. M., Penninx, B. W. J. H. & Smit, J. H., 15 Feb 2019, Journal of Affective Disorders. Elsevier B.V., p. 180-187 8 p. (Journal of Affective Disorders; vol. 245).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular Psychiatry, (2018), 10.1038/s41380-018-0118-1)

16p11.2 European Consortium, for the ENIGMA-CNV working group, 2019, In : Molecular Psychiatry.

Research output: Contribution to journalErratumAcademicpeer-review

Delayed sleep-onset and biological age: late sleep-onset is associated with shorter telomere length

Wynchank, D., Bijlenga, D., Penninx, B. W., Lamers, F., Beekman, A. T., Kooij, J. J. S. & Verhoeven, J. E., 9 Oct 2019, In : Sleep. 42, 10

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depression and eating styles are independently associated with dietary intake

Paans, NPG., Gibson-Smith, DJ., Bot, M., van Strien, T., Brouwer, I., Visser, M. & Penninx, BWJH., 2019, In : Appetite. 134, p. 103-110

Research output: Contribution to journalArticleAcademicpeer-review

Depression and obesity: evidence of shared biological mechanisms

Milaneschi, Y., Simmons, W. K., van Rossum, E. F. C. & Penninx, B. WJH., 1 Jan 2019, In : Molecular Psychiatry. 24, 1, p. 18-33 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Differential associations of locus of control with anxiety, depression and life-events: A five-wave, nine-year study to test stability and change

Hovenkamp-Hermelink, J. H. M., Jeronimus, B. F., van der Veen, D. C., Spinhoven, P., Penninx, B. W. J. H., Schoevers, R. A. & Riese, H., 2019, In : Journal of Affective Disorders. 253, p. 26-34

Research output: Contribution to journalArticleAcademicpeer-review

Evaluating the evidence for biotypes of depression: Methodological replication and extension of Drysdale et al. (2017)

Dinga, R., Schmaal, L., Penninx, B. W. J. H., van Tol, M. J., Veltman, D. J., van Velzen, L., Mennes, M., van der Wee, N. J. A. & Marquand, A. F., 1 Jan 2019, In : NeuroImage: Clinical. 22, 101796.

Research output: Contribution to journalArticleAcademicpeer-review

Examining the antidepressant scattergun approach

Penninx, B., 2019, In : The Lancet Psychiatry. 6, 11, p. 878-879

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Genetic architecture of subcortical brain structures in 38,851 individuals

CHARGE, 1 Nov 2019, In : Nature Genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

23and Me Research Team, 2019, In : Nature Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci

Thio, C. H. L., Reznichenko, A., van der Most, P. J., Kamali, Z., Vaez, A., Smit, J. H., Penninx, B. W. J. H., Haller, T., Mihailov, E., Metspalu, A., Damman, J., de Borst, M. H., van der Harst, P., Verweij, N., Navis, G. J., Gansevoort, R. T., Nolte, I. M. & Snieder, H., 2019, In : American Journal of Nephrology. p. 193-202

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In : Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2019, In : American Journal of Psychiatry. 176, 8, p. 651-660

Research output: Contribution to journalArticleAcademicpeer-review

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, 2019, In : Nature Genetics.

Research output: Contribution to journalArticleAcademicpeer-review

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2019, In : Nature Communications. 10, 1, 2548.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: Mega-analytic findings from a large multi-site cohort

ENIGMA-MDD Consortium, 2019, In : Psychological Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

BBMRI Metabolomics Consortium, 16 Apr 2019, In : Neurology. 92, 16, p. e1899-e1911

Research output: Contribution to journalArticleAcademicpeer-review

Longitudinal Association Between Depression and Inflammatory Markers: Results From the Netherlands Study of Depression and Anxiety

Lamers, F., Milaneschi, Y., Smit, J. H., Schoevers, R. A., Wittenberg, G. & Penninx, B. W. J. H., 1 May 2019, In : Biological Psychiatry. 85, 10, p. 829-837 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Longitudinal course of suicidal ideation and predictors of its persistence – A NESDA study

Kivelä, L., Krause-Utz, A., Mouthaan, J., Schoorl, M., de Kleine, R., Elzinga, B., Eikelenboom, M., Penninx, B. WJH., van der Does, W. & Antypa, N., 1 Oct 2019, In : Journal of Affective Disorders. 257, p. 365-375 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Long-term glucocorticoid levels measured in hair in patients with depressive and anxiety disorders

Gerritsen, L., Staufenbiel, S. M., Penninx, B. W. J. H., van Hemert, A. M., Noppe, G., de Rijke, Y. B. & van Rossum, E. F. C., 2019, In : Psychoneuroendocrinology. 101, p. 246-252

Research output: Contribution to journalArticleAcademicpeer-review

Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults

Diniz, B. S., Reynolds, C. F., Sibille, E., Bot, M. & Penninx, B. W. J. H., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 198.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Measuring social support in psychiatric patients and controls: Validation and reliability of the shortened Close Persons Questionnaire

Hanssen, D. J. C., Rabeling-Keus, I. M., Lucassen, P. L. B. J., Naarding, P., van den Brink, R. H. S., Comijs, H. C., Penninx, B. W. J. H. & Oude Voshaar, R. C., 2019, In : Journal of Psychiatric Research. 116, p. 118-125

Research output: Contribution to journalArticleAcademicpeer-review

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

eQTLGen Consortium & BIOS Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 3300.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls

BBMRI-NL Metabolomics Consortium, 1 Jan 2019, In : Biological Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Methylome-wide association studies for Major Depressive Disorder in blood overlap with methylation results from brain and large-scale GWAS

Aberg, K., Dean, B., Shabalin, A., Zhao, M., Chan, R., Hattab, M., van Grootheest, G., Han, L., Aghajani, M., Milaneschi, Y., Jansen, R., Xie, L., Clark, S., Penninx, B. & van den Oord, E., 2019, In : European Neuropsychopharmacology. 29, p. S807-S808

Research output: Contribution to journalMeeting AbstractAcademic

Mindful eating and change in depressive symptoms: Mediation by psychological eating styles

Winkens, L. H. H., van Strien, T., Brouwer, I. A., Penninx, B. W. J. H. & Visser, M., 2019, In : Appetite. 133, p. 204-211

Research output: Contribution to journalArticleAcademicpeer-review

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

COGENT-Kidney Consortium, EPIC-InterAct Consortium, Understanding Society Scientific group & Lifelines Cohort, 2019, In : Nature Genetics. 51, 4, p. 636-648

Research output: Contribution to journalArticleAcademicpeer-review

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

Lifelines Cohort Study, 2019, In : Nature Communications. 10, 1, 376.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Multinutrient Supplementation for Prevention of Major Depressive Disorder in Overweight Adults - Reply

Brouwer, I. A., Penninx, B. W. H. J. & Visser, M., 23 Jul 2019, In : JAMA - Journal of the American Medical Association. 322, 4, p. 366-367 2 p.

Research output: Contribution to journalLetterAcademicpeer-review