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Research Output 1994 2020

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2020

A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., A. C. ’t Hoen, P., van Meurs, J., Brooks, A. I., Boomsma, D. I., Penninx, B. W. J. H. & BIOS Consortium, Feb 2020, In : European Journal of Human Genetics. 28, 2, p. 253-263

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 206 othersAgerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Howard, D. M., Ising, M., Jansen, R., Jones, I., Jones, L. A., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M., O’Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C., Breen, G. & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23 Jan 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

BBMRI Metabolomics Consortium, 2020, In : Nature Communications. 11, 1, 39.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Performance of methods to conduct mediation analysis with time-to-event outcomes

Burgos Ochoa, L., Rijnhart, J. J. M., Penninx, B. W., Wardenaar, K. J., Twisk, J. W. R. & Heymans, M. W., 1 Feb 2020, In : Statistica Neerlandica. 74, 1, p. 72-91 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Social dysfunction in mood disorders and schizophrenia: Clinical modulators in four independent samples

Porcelli, S., Kasper, S., Zohar, J., Souery, D., Montgomery, S., Ferentinos, P., Rujescu, D., Mendlewicz, J., Merlo Pich, E., Pollentier, S., Penninx, B. W. J. H. & Serretti, A., 20 Apr 2020, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 99, 109835.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time

Struijs, S. Y., Lamers, F., Verdam, M. G. E., van Ballegooijen, W., Spinhoven, P., van der Does, W. & Penninx, B. W. J. H., 1 Jan 2020, In : Journal of Affective Disorders. 260, p. 77-83 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2019

A 6-year longitudinal study of predictors for suicide attempts in major depressive disorder

Eikelenboom, M., Beekman, A. T. F., Penninx, B. W. J. H. & Smit, J. H., 1 Apr 2019, In : Psychological Medicine. 49, 6, p. 911-921 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M., Ghasemi, S. & 34 othersXu, Y., Horn, K., Noce, D., van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boehnke, M., Boerwinkle, E., Boissel, M., Bottinger, E. P., Boutin, T. S., Brenner, H., Brumat, M., Burkhardt, R., Butterworth, A. S., Campana, E., Milaneschi, Y., Penninx, B. W. J. H., Köttgen, A., Pattaro, C., Lifelines Cohort Study & V. A. Million Veteran Program, 1 Jun 2019, In : Nature Genetics. 51, 6, p. 957-972

Research output: Contribution to journalArticleAcademicpeer-review

A methylation study of long-term depression risk

Clark, S. L., Hattab, M. W., Chan, R. F., Shabalin, A. A., Han, L. K. M., Zhao, M., Smit, J. H., Jansen, R., Milaneschi, Y., Xie, L. Y., van Grootheest, G., Penninx, B. W. J. H., Aberg, K. A. & van den Oord, E. J. C. G., 9 Sep 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Anxiety sensitivity, its stability and longitudinal association with severity of anxiety symptoms

Hovenkamp-Hermelink, J. H. M., van der Veen, D. C., Oude Voshaar, R. C., Batelaan, N. M., Penninx, B. W. J. H., Jeronimus, B. F., Schoevers, R. A. & Riese, H., 1 Dec 2019, In : Scientific Reports. 9, 1, 4314.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms

Arias-Vásquez, A., Groffen, A. J., Spijker, S., Ouwens, K. G., Klein, M., Vojinovic, D., Galesloot, T. E., Bralten, J., Hottenga, J. J., van der Most, P. J., Kattenberg, V. M., Pool, R., Nolte, I. M., Penninx, B. W. J. H., Fedko, I. O., Dolan, C. V., Nivard, M. G., den Braber, A., van Duijn, C. M., Hoekstra, P. J. & 16 othersBuitelaar, J. K., Kiemeney, L. A., Hoogman, M., Middeldorp, C. M., Draisma, H. H. M., Vermeulen, S. H., Sánchez-Mora, C., Ramos-Quiroga, J. A., Ribasés, M., Hartman, C. A., Kooij, J. J. S., Amin, N., Smit, A. B., Franke, B., Boomsma, D. I. & The EAGLE-ADHD Consortium, 15 May 2019, In : Behavior Genetics. 49, 3, p. 270-285 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

Milaneschi, Y., Peyrot, W. J., Nivard, M. G., Mbarek, H., Boomsma, D. I. & W.J.H. Penninx, B., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 219.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of a priori dietary patterns with depressive symptoms: A harmonised meta-analysis of observational studies

Nicolaou, M., Colpo, M., Vermeulen, E., Elstgeest, L. E. M., Cabout, M., Gibson-Smith, D., Knuppel, A., Sini, G., Schoenaker, D. A. J. M., Mishra, G. D., Lok, A., Penninx, B. W. J. H., Bandinelli, S., Brunner, E. J., Zwinderman, A. H., Brouwer, I. A., Visser, M. & on behalf of the MooDFOOD consortium, 14 Aug 2019, In : Psychological Medicine.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of food groups with depression and anxiety disorders

Gibson-Smith, D., Bot, M., Brouwer, I. A., Visser, M., Giltay, E. J. & Penninx, B. W. J. H., 3 Apr 2019, In : European Journal of Nutrition.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for Major Depressive Disorder and white matter microstructure in the UK Biobank

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T. K., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M. & 51 othersAndlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Bigdeli, T. B., Beekman, A. T. F., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23andMe Research team, Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., 1 Jan 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Associations of depressive symptoms and history with three a priori diet quality indices in middle-aged and older adults

Elstgeest, L. E. M., Winkens, L. H. H., Penninx, B. W. J. H., Brouwer, I. A. & Visser, M., 15 Apr 2019, In : Journal of Affective Disorders. 249, p. 394-403 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bidirectional associations between food groups and depressive symptoms: longitudinal findings from the Invecchiare in Chianti (InCHIANTI) study

Elstgeest, L. E. M., Visser, M., Penninx, B. W. J. H., Colpo, M., Bandinelli, S. & Brouwer, I. A., 28 Feb 2019, In : British Journal of Nutrition. 121, 4, p. 439-450 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Biomarker-based subtyping of depression and anxiety disorders using Latent Class Analysis. A NESDA study

Beijers, L., Wardenaar, K. J., Bosker, F. J., Lamers, F., van Grootheest, G., de Boer, M. K., Penninx, B. W. J. H. & Schoevers, R. A., 1 Mar 2019, In : Psychological Medicine. 49, 4, p. 617-627 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Body mass index in obsessive-compulsive disorder

Abramovitch, A., Anholt, G. E., Cooperman, A., van Balkom, A. J. L. M., Giltay, E. J., Penninx, B. W. & van Oppen, P., 15 Feb 2019, In : Journal of Affective Disorders. 245, p. 145-151 7 p., 245.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

Han, L. KM., Dinga, R., Hahn, T., Ching, C., Eyler, L., Aftanas, L., Aghajani, M., Aleman, A., Baune, B., Berger, K., Brak, I., Filho, G. B., Carballedo, A., Connolly, C., Couvy-Duchesne, B., Cullen, K., Dannlowski, U., Davey, C., Dima, D., Duran, F. & 126 othersEnneking, V., Filimonova, E., Frenzel, S., Frodl, T., Fu, C., Godlewska, B., Gotlib, I., Grabe, H., Groenewold, N., Grotegerd, D., Gruber, O., Hall, G., Harrison, B., Hatton, S., Hermesdorf, M., Hickie, I., Ho, T., Hosten, N., Jansen, A., Kahler, C., Kircher, T., Klimes-Dougan, B., Kramer, B., Krug, A., Lagopoulos, J., Leenings, R., MacMaster, F., MacQueen, G., McIntosh, A., McLellan, Q., McMahon, K., Medland, S., Mueller, B., Mwangi, B., Osipov, E., Portella, M., Pozzi, E., Reneman, L., Repple, J., Rosa, P., Sacchet, M., Saemann, P., Schnell, K., Schrantee, A., Simulionyte, E., Soares, J., Sommer, J., Stein, D., Steinstrater, O., Strike, L., Thomopoulos, S., Tol, M-J. V., Veer, I., Vermeiren, R., Walter, H., Wee, N. V. D., Werff, S. V. D., Whalley, H., Winter, N., Wittfeld, K., Wright, M., Wu, M-J., Volzke, H., Yang, T., Zannias, V., Zubicaray, G. D., Zunta-Soares, G., Abe, C., Alda, M., Andreassen, O., Boen, E., Bonnin, C., Canales-Rodriguez, E., Cannon, D., Caseras, X., Chaim-Avancini, T., Elvsashagen, T., Favre, P., Foley, S., Fullerton, J., Goikolea, J., Haarman, B., Hajek, T., Henry, C., Houenou, J., Howells, F., Ingvar, M., Kuplicki, R., Lafer, B., Landen, M., Machado-Vieira, R., Malt, U., McDonald, C., Mitchell, P., Nabulsi, L., Otaduy, M., Overs, B., Polosan, M., Pomarol-Clotet, E., Radua, J., Rive, M., Roberts, G., Ruhe, H., Salvador, R., Sarro, S., Satterthwaite, T., Savitz, J., Schene, A., Schofield, P., Serpa, M., Sim, K., Soeiro-de-Souza, M., Sutherland, A., Temmingh, H., Timmons, G., Uhlmann, A., Vieta, E., Wolf, D., Zanetti, M., Jahanshad, N., Thompson, P., Veltman, D., Penninx, B., Marquand, A., Cole, J. & Schmaal, L., 2019, In : Biorxiv. p. 560623

Research output: Contribution to journalArticleAcademic

Can chronotype function as predictor of a persistent course of depressive and anxiety disorder?

Druiven, S. J. M., Knapen, S. E., Penninx, B. W. J. H., Antypa, N., Schoevers, R. A., Riese, H. & Meesters, Y., 1 Jan 2019, In : Journal of Affective Disorders. 242, p. 159-164 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Childhood maltreatment, vulnerability characteristics and adult incident common mental disorders: 3-year longitudinal data among >10,000 adults in the general population

ten Have, M., de Graaf, R., van Dorsselaer, S., Tuithof, M., Kleinjan, M. & Penninx, B. W. J. H., 2019, In : Journal of Psychiatric Research. 113, p. 199-207

Research output: Contribution to journalArticleAcademicpeer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Glanville, K. P., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J. & 33 othersde Geus, E. J. C., Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Magnusson, P. K., McGuffin, P., McIntosh, A. M., Milaneschi, Y., Mors, O., Mostafavi, S., Müller-Myhsok, B., Pedersen, N. L., Penninx, B. W. J. H., Potash, J. B., Preisig, M., Ripke, S., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Weissman, M. M. & O'Reilly, P. F., 5 Aug 2019, In : Biological Psychiatry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Course and predictors of symptomatic remission in late-life schizophrenia: A 5-year follow-up study in a Dutch psychiatric catchment area

Lange, S. M. M., Meesters, P. D., Stek, M. L., Wunderink, L., Penninx, B. W. J. H. & Rhebergen, D., 1 Jul 2019, In : Schizophrenia Research. 209, p. 179-184 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Decreased functional connectivity of the insula within the salience network as an indicator for prospective insufficient response to antidepressants

Geugies, H., Opmeer, E. M., Marsman, J. B. C., Figueroa, C. A., van Tol, M. J., Schmaal, L., van der Wee, N. J. A., Aleman, A., Penninx, B. W. J. H., Veltman, D. J., Schoevers, R. A. & Ruhé, H. G., 2019, In : NeuroImage: Clinical. 24, 102064.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Delayed sleep-onset and biological age: late sleep-onset is associated with shorter telomere length

Wynchank, D., Bijlenga, D., Penninx, B. W., Lamers, F., Beekman, A. T., Kooij, J. J. S. & Verhoeven, J. E., 1 Jan 2019, In : Sleep. 42, 10

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depression and eating styles are independently associated with dietary intake

Paans, NPG., Gibson-Smith, DJ., Bot, M., van Strien, T., Brouwer, I., Visser, M. & Penninx, BWJH., 2019, In : Appetite. 134, p. 103-110

Research output: Contribution to journalArticleAcademicpeer-review

Depressive symptom clusters in relation to body weight status: Results from two large European multicenter studies

Baldofski, S., Mauche, N., Dogan-Sander, E., Bot, M., Brouwer, I. A., Paans, N. P. G., Cabout, M., Gili, M., van Grootheest, G., Hegerl, U., Owens, M., Roca, M., Visser, M., Watkins, E., Penninx, B. W. J. H., Kohls, E. & the MooDFOOD Prevention Trial Investigators, 21 Nov 2019, In : Frontiers in Psychiatry. 10, 858.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Differences between unipolar mania and bipolar-I disorder: Evidence from nine epidemiological studies

Angst, J., Rössler, W., Ajdacic-Gross, V., Angst, F., Wittchen, H. U., Lieb, R., Beesdo-Baum, K., Asselmann, E., Merikangas, K. R., Cui, L., Andrade, L. H., Viana, M. C., Lamers, F., Penninx, B. W. JH., de Azevedo Cardoso, T., Jansen, K., Dias de Mattos Souza, L., Azevedo da Silva, R., Kapczinski, F., Grobler, C. & 3 othersGholam-Rezaee, M., Preisig, M. & Vandeleur, C. L., 1 Jan 2019, In : Bipolar Disorders. 21, 5, p. 437-448 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Differential associations of locus of control with anxiety, depression and life-events: A five-wave, nine-year study to test stability and change

Hovenkamp-Hermelink, J. H. M., Jeronimus, B. F., van der Veen, D. C., Spinhoven, P., Penninx, B. W. J. H., Schoevers, R. A. & Riese, H., 15 Jun 2019, In : Journal of Affective Disorders. 253, p. 26-34 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of food-related behavioral activation therapy on food intake and the environmental impact of the diet: results from the MooDFOOD prevention trial

Grasso, A. C., Olthof, M. R., van Dooren, C., Roca, M., Gili, M., Visser, M., Cabout, M., Bot, M., Penninx, B., van Grootheest, G., Kohls, E., Hegerl, U., Owens, M., Watkins, E., Brouwer, I. A. & the MooDFOOD Prevention Trial Investigators, 1 Jan 2019, In : European Journal of Nutrition.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Evaluating the evidence for biotypes of depression: Methodological replication and extension of Drysdale et al. (2017)

Dinga, R., Schmaal, L., Penninx, B. W. J. H., van Tol, M. J., Veltman, D. J., van Velzen, L., Mennes, M., van der Wee, N. J. A. & Marquand, A. F., 1 Jan 2019, In : NeuroImage: Clinical. 22, 101796.

Research output: Contribution to journalArticleAcademicpeer-review

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 34 othersLi, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Penninx, B. W. J. H., Oosterlaan, J., de Geus, E. J. C., Veltman, D. J., Thompson, P. M., Seshadri, S., Ikram, M. A. & CHARGE, Nov 2019, In : Nature Genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L., Caplin, A. H. & 37 othersChen, C-Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Jansen, R., Penninx, B., Peyrot, W. J., Evans, D. M., Milaneschi, Y., Posthuma, D., 23and Me Research Team, Schunk, D., Stein, M. B., Svento, R., Tiemeier, H., Timmers, P. R. H. J., Turley, P., Ursano, R. J., Wagner, G. G., Wilson, J. F., Gratten, J., Lee, J. J., Cesarini, D., Benjamin, D. J., Koellinger, P. D. & Beauchamp, J. P., 1 Feb 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

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Genome-Wide Association Scan of serum urea in European populations identifies two novel loci

Thio, C. H. L., Reznichenko, A., van der Most, P. J., Kamali, Z., Vaez, A., Smit, J. H., Penninx, B. W. J. H., Haller, T., Mihailov, E., Metspalu, A., Damman, J., de Borst, M. H., van der Harst, P., Verweij, N., Navis, G. J., Gansevoort, R. T., Nolte, I. M. & Snieder, H., 2019, In : American Journal of Nephrology. 49, p. 193-202

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Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., Eriksson, E., Lavebratt, C., Allgulander, C., Friedrich, N., Becker, J., Hecker, J., Rambau, S., Conrad, R., Geiser, F., McMahon, F. J., Moebus, S., Hess, T., Buerfent, B. C., Hoffmann, P. & 33 othersHerms, S., Heilmann-Heimbach, S., Kockum, I., Olsson, T., Alfredsson, L., Weber, H., Alpers, G. W., Arolt, V., Fehm, L., Fydrich, T., Gerlach, A. L., Hamm, A., Kircher, T., Pané-Farré, C. A., Pauli, P., Rief, W., Ströhle, A., Plag, J., Lang, T., Wittchen, H. U., Mattheisen, M., Meier, S., Metspalu, A., Domschke, K., Reif, A., Hovatta, I., Lindefors, N., Andersson, E., de Geus, E. J. C., Penninx, B. W. J. H., Deckert, J., Schumacher, J. & NESDA, 1 Jan 2019, In : Molecular Psychiatry.

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Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohorts

Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In : Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

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Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium, 12 Dec 2019, In : Cell. 179, 7, p. 1469-1482.e11

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Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

Timmers, P. R., Mounier, N., Lall, K., Fischer, K., Ning, Z., Feng, X., Bretherick, A. D., Clark, D. W., Shen, X., Esko, T., Kutalik, Z., Wilson, J. F., Joshi, P. K. & eQTLGen Consortium, 15 Jan 2019, In : eLife. 8

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GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., Anjorin, A., Corvin, A., Sanders, A. R., Forstner, A. J., Reif, A., Koller, A. C., Tkowska, B. S., Baune, B. T., Müller-Myhsok, B., Penninx, B. W. J. H. & 35 othersPato, C., Zai, C., Rujescu, D., Hougaard, D. M., Quested, D., Levinson, D. F., Binder, E. B., Byrne, E. M., Agerbo, E., Streit, F., Mayoral, F., Bellivier, F., Degenhardt, F., Breen, G., Morken, G., Turecki, G., Rouleau, G. A., Grabe, H. J., Völzke, H., Jones, I., Giegling, I., Agartz, I., Melle, I., Lawrence, J., Walters, J. T. R., Strohmaier, J., Shi, J., Hauser, J., Biernacka, J. M., Milaneschi, Y., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 1 Jan 2019, In : American Journal of Psychiatry. 176, 8, p. 651-660

Research output: Contribution to journalArticleAcademicpeer-review

Identification of common genetic risk variants for autism spectrum disorder

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., Awashti, S., Belliveau, R., Bettella, F., Buxbaum, J. D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Cerrato, F., Chambert, K., Christensen, J. H., Churchhouse, C. & 33 othersDellenvall, K., Demontis, D., de Rubeis, S., Devlin, B., Djurovic, S., Dumont, A. L., Goldstein, J. I., Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Posthuma, D., Schoevers, R., Smit, J. H., de Geus, E. J. C., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, Stefansson, K., Geschwind, D. H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Bo Mortensen, P., Neale, B. M., Daly, M. J. & Børglum, A. D., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

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Increased serum levels of leptin and insulin in both schizophrenia and major depressive disorder: A cross-disorder proteomics analysis

Çakici, N., Bot, M., Lamers, F., Janssen, T., van der Spek, P. J., de Haan, L., Bahn, S., Penninx, B. W. J. H. & van Beveren, N. J. M., 1 Jul 2019, In : European Neuropsychopharmacology. 29, 7, p. 835-846 12 p.

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Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G. K., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O’Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C., Jones, M. J. & 25 othersLin, D. T. S., MacIsaac, J. L., Kobor, M. S., Koen, N., Zar, H. J., Koenen, K. C., Dalvie, S., Stein, D. J., Kondofersky, I., Müller, N. S., Beekman, A. T. F., Jansen, R., Middeldorp, C. M., Milaneschi, Y., Peyrot, W. J., Schoevers, R., Smit, J. H., de Geus, E. J. C., Penninx, B. W. J. H., Posthuma, D., Smit, J. H., Theis, F. J., Räikkönen, K., Binder, E. B. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 2548.

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Integrating proteomic, sociodemographic and clinical data to predict future depression diagnosis in subthreshold symptomatic individuals

Han, S. Y. S., Cooper, J. D., Ozcan, S., Rustogi, N., Penninx, B. W. J. H. & Bahn, S., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 1 p.

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Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: Mega-analytic findings from a large multi-site cohort

Tozzi, L., Garczarek, L., Janowitz, D., Stein, D. J., Wittfeld, K., Dobrowolny, H., Lagopoulos, J., Hatton, S. N., Hickie, I. B., Carballedo, A., Brooks, S. J., Vuletic, D., Uhlmann, A., Veer, I. M., Walter, H., Bülow, R., Völzke, H., Klinger-König, J., Schnell, K., Schoepf, D. I. & 32 othersGrotegerd, D., Opel, N., Dannlowski, U., Kugel, H., Schramm, E., Konrad, C., Kircher, T., Jüksel, D. I., Nenadic, I., Krug, A., Hahn, T., Steinsträter, O., Redlich, R., Zaremba, D., Zurowski, B., Fu, C. H. Y., DIma, D., Cole, J., Grabe, H. J., Connolly, C. G., Yang, T. T., Ho, T. C., Lewinn, K. Z., Li, M., Groenewold, N. A., Salminen, L. E., Walter, M., Penninx, B. W. J. H., Veltman, D. J., Schmaal, L., Frodl, T. & ENIGMA-MDD Consortium, 14 May 2019, In : Psychological Medicine.

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Involvement of inflammatory gene expression pathways in depressed patients with hyperphagia

de Kluiver, H., Jansen, R., Milaneschi, Y. & Penninx, B. W. J. H., 1 Dec 2019, In : Translational Psychiatry. 9, 1, 193.

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