Projects per year
Personal profile
Research interests
My overall research objective is to investigate the neurobiological background of stress resilience and vulnerability including (epi)genetic, neuroendocrine, and brain circuitry factors. I have obtained degrees in Pharmacy, Medicine and Law. My preclinical research during my PhD training concerned the genetic and molecular basis of stress reactivity using pharmacological, genetic and molecular techniques. With over 15 peer-reviewed publications and several international collaborations, this led to a cum laude PhD thesis in 2009. During my study of Pharmacy, subsequent PhD training, and my study of Medicine, I saw a great unmet need for effective treatment options in psychiatric patients which convinced me to start my psychiatry residencies. In daily practice, I diagnose and treat patients with psychiatric disorders (including depression, psychosis, and bipolar disorder) which directly links my fundamental research activities to a clinical setting.
It is my drive is to look for solutions in both fundamental preclinical and applied clinical research and promote the exchange of ideas between those two research approaches. My research has contributed how (traumatic) stress increases the risk for psychiatric disorders and helped to identify who is (not) at risk. I am currently leading epidemiological and experimental studies examining both genetic and neuroimaging parameters, to furtherdisentangle and integrate the biological and psychological determinants of stress resilience.
External positions
Scientific Advisory Board, Hersenstichting (Dutch Brain Foundation)
1 Jun 2022 → …
Editorial Board, European College for Neuropsychopharmacology (ECNP)
1 Sep 2021 → …
Wetenschappelijke Adviesraad Commissie Geneesmiddelen, Zorginstituut Nederland
1 Sep 2021 → …
Chair Thematic Working Group Resilience, European College for Neuropsychopharmacology (ECNP)
1 Mar 2020 → …
Network
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REACT: Brain dynamics in childhood trauma-related depression
Pasteuning, J., Sep, M., Schoonheim, M. & Vinkers, C.
01/01/2022 → …
Project: Research
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inflaMED: Precision psychiatry: Anti-inflammatory medication in Immuno-metabolic depression
Lamers, F., Milaneschi, Y., Penninx, B., Vinkers, C. & Zwiep, J.
01/09/2021 → 31/08/2025
Project: Research
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RESET: REStoring mood in Early life Trauma
Linsen, F., Gathier, A., Broeder, C., Sep, M., Verhoeven, J., Schoonheim, M., van Oppen, P., Penninx, B. & Vinkers, C.
01/01/2020 → …
Project: Research
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OPERA: Netherlands study of Optimal, Personal Antidepressant use
Penninx, B., Bot, M., Maarsingh, O., Vinkers, C. & Bet, P.
01/01/2019 → 31/12/2023
Project: Research
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The impact of the prolonged COVID-19 pandemic on stress resilience and mental health: A critical review across waves
Manchia, M., Gathier, A. W., Yapici-Eser, H., Schmidt, M. V., de Quervain, D., van Amelsvoort, T., Bisson, J. I., Cryan, J. F., Howes, O. D., Pinto, L., van der Wee, N. J., Domschke, K., Branchi, I. & Vinkers, C. H., 1 Feb 2022, In: European Neuropsychopharmacology. 55, p. 22-83 62 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Dorsal attention network centrality increases during recovery from acute stress exposure
Broeders, T. A. A., Schoonheim, M. M., Vink, M., Douw, L., Geurts, J. J. G., van Leeuwen, J. M. C. & Vinkers, C. H., 1 Jan 2021, In: NeuroImage: Clinical. 31, 102721.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Antidepressant Discontinuation: In Need of Scientific Evidence
Vinkers, C. H., Ruhé, H. G. & Penninx, B. W., 1 Sep 2021, In: Journal of Clinical Psychopharmacology. 41, 5, p. 512-515 4 p.Research output: Contribution to journal › Article › Academic › peer-review
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Burnout urgently needs robust research
Vinkers, C. H. & Schaafsma, F. G., 8 Apr 2021, In: Nature. 592, 7853, p. 188-188Research output: Contribution to journal › Letter › Academic › peer-review
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Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans
Houtepen, L. C., Vinkers, C. H., Carrillo-Roa, T., Hiemstra, M., van Lier, P. A., Meeus, W., Branje, S., Heim, C. M., Nemeroff, C. B., Mill, J., Schalkwyk, L. C., Creyghton, M. P., Kahn, R. S., Joëls, M., Binder, E. B. & Boks, M. P. M., 21 Mar 2016, In: Nature Communications. 7, p. 10967Research output: Contribution to journal › Article › Academic › peer-review
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Integration of psychological and biological determinants of stress and trauma: a novel road for new interventions?
Christiaan Vinkers (Speaker)
10 Jun 2022Activity: Talk or presentation › Invited talk
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ZonMw - The Netherlands Organisation for Health Research and Development (External organisation)
Christiaan Vinkers (Chair)
2021 → …Activity: Membership › Membership of committee
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Zorginstituut Nederland (External organisation)
Christiaan Vinkers (Chair)
2021Activity: Membership › Membership of committee
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Royal Dutch Academy of Arts and Sciences (KNAW) (External organisation)
Christiaan Vinkers (Member)
2020Activity: Membership › Membership of committee
Press/Media
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Het laatste nieuws over antidepressiva | Margriet
10/11/2022
1 Media contribution
Press/Media: Interview
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Brandstof laat zien hoezeer we doordrongen zijn van ’t idee dat stress erbij hoort
05/10/2022
1 Media contribution
Press/Media: Interview
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“Een burn-out bestaat niet”, “Het leven is een zure bom”
26/09/2022
1 Media contribution
Press/Media: Interview
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Stress onder de loep: wat gebeurt er in ons brein als we stress hebben?
19/09/2022
1 Media contribution
Press/Media: Interview
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Psychiater Christiaan Vinkers wil “liefdevol bommetje” leggen onder burn-out
17/09/2022
1 Media contribution
Press/Media: Interview
Prizes
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American College for Neuropsychopharmacology (ACNP) Travel Award
Vinkers, Christiaan (Recipient), 2020
Prize
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Society for Biological Psychiatry (SOBP) Travel Fellowship
Vinkers, Christiaan (Recipient), 2020
Prize