My main research interest is infections of the musculoskeletal system, especially diabetic foot infections. In 2002, I wrote a PhD thesis on diabetic foot complications, based on research I performed in San Antonio, Texas. Since then I have continued to study the diabetic foot and diabetic foot infections in particular. I have combined it with research to other musculoskeletal infections, e.g., prosthetic joint prosthesis associated infection. I am also involved in writing guidelines for treatment of diabetic foot complications for the Infectious Diseases Society of America, the International Working Group on the Diabetic Foot and the Dutch Internist Society (NIV). I also chair the Dutch guideline committee for prosthetic joint associated infections.