Egbert Smit

PROF.DR., (Principal Investigator)

20042018
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Research Output 2004 2018

Afatinib and Cetuximab in Four Patients With EGFR Exon 20 Insertion-Positive Advanced NSCLC

van Veggel, B., de Langen, A. J., Hashemi, S. M. S., Monkhorst, K., Heideman, D. A. M., Thunnissen, E. & Smit, E. F., 1 Aug 2018, In : Journal of Thoracic Oncology. 13, 8, p. 1222-1226 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Crizotinib treatment for patients with EGFR mutation positive NSCLC that acquire cMET amplification after EGFR TKI therapy results in short-lived and heterogeneous responses

van Veggel, B., de Langen, A. J., Hashemi, S., Monkhorst, K., Rosenberg, E. H., Heideman, D. A. M., Radonic, T. & Smit, E. F., 2018, In : Lung Cancer. 124, p. 130-134 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors

Fassunke, J., Müller, F., Keul, M., Michels, S., Dammert, M. A., Schmitt, A., Plenker, D., Lategahn, J., Heydt, C., Brägelmann, J., Tumbrink, H. L., Alber, Y., Klein, S., Heimsoeth, A., Dahmen, I., Fischer, R. N., Scheffler, M., Ihle, M. A., Priesner, V., Scheel, A. H. & 19 othersWagener, S., Kron, A., Frank, K., Garbert, K., Persigehl, T., Püsken, M., Haneder, S., Schaaf, B., Rodermann, E., Engel-Riedel, W., Felip, E., Smit, E. F., Merkelbach-Bruse, S., Reinhardt, H. C., Kast, S. M., Wolf, J., Rauh, D., Büttner, R. & Sos, M. L., 7 Nov 2018, In : Nature Communications. 9, 1, p. 4655

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

P2.13-42 Osimertinib Treatment for Patients with EGFR exon 20 Insertion Positive Non-Small-Cell Lung Cancer

Van Veggel, B., Van Der Wekken, A., Hashemi, S., Cornelissen, R., Monkhorst, K., Heideman, D., Radonic, T., Schuuring, E., Smit, E. & De Langen, J., 22 Oct 2018, In : Journal of Thoracic Oncology. 13, 10, p. S815

Research output: Contribution to journalArticleAcademic

Predictive biomarkers for response to EGFR-directed monoclonal antibodies for advanced squamous cell lung cancer

Bonomi, P. D., Gandara, D., Hirsch, F. R., Kerr, K. M., Obasaju, C., Paz-Ares, L., Bellomo, C., Bradley, J. D., Bunn, P. A., Culligan, M., Jett, J. R., Kim, E. S., Langer, C. J., Natale, R. B., Novello, S., Pérol, M., Ramalingam, S. S., Reck, M., Reynolds, C. H., Smit, E. F. & 5 othersSocinski, M. A., Spigel, D. R., Vansteenkiste, J. F., Wakelee, H. & Thatcher, N., 2018, In : Annals of Oncology. 29, 8, p. 1701-1709 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review