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Research Output 2008 2019

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2019

2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors

Cascioferro, S., Parrino, B., Petri, G. L., Cusimano, M. G., Schillaci, D., di Sarno, V., Musella, S., Giovannetti, E., Cirrincione, G. & Diana, P., 2019, In : European Journal of Medicinal Chemistry. 167, p. 200-210

Research output: Contribution to journalArticleAcademicpeer-review

Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line

van der Steen, N., Leonetti, A., Keller, K., Dekker, H., Funel, N., Lardon, F., Ruijtenbeek, R., Tiseo, M., Rolfo, C., Pauwels, P., Peters, G. J. & Giovannetti, E., 2019, In : Biochemical Pharmacology. 166, p. 128-138

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacogenetics of treatments for pancreatic cancer

el Hassouni, B., Li Petri, G., Liu, D. S. K., Cascioferro, S., Parrino, B., Hassan, W., Diana, P., Ali, A., Frampton, A. E. & Giovannetti, E., 2019, In : Expert Opinion on Drug Metabolism and Toxicology. 15, 6, p. 437-447

Research output: Contribution to journalArticleAcademicpeer-review

RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment

Balboni, B., el Hassouni, B., Honeywell, R. J., Sarkisjan, D., Giovannetti, E., Poore, J., Heaton, C., Peterson, C., Benaim, E., Lee, Y. B., Kim, D. J. & Peters, G. J., 2019, In : Expert Opinion on Investigational Drugs. 28, 4, p. 311-322

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

Sciarrillo, R., Wojtuszkiewicz, A., El Hassouni, B., Funel, N., Gandellini, P., Lagerweij, T., Buonamici, S., Blijlevens, M., Zeeuw van der Laan, E. A., Zaffaroni, N., Deraco, M., Kusamura, S., Würdinger, T., Peters, G. J., Molthoff, C. F. M., Jansen, G., Kaspers, G. J. L., Cloos, J. & Giovannetti, E., Jan 2019, In : EBioMedicine. 39, p. 215-225

Research output: Contribution to journalArticleAcademicpeer-review

2018

5'-nucleotidase cN-II emerges as a new predictive biomarker of response to gemcitabine/platinum combination chemotherapy in non-small cell lung cancer

Toffalorio, F., Santarpia, M., Radice, D., Jaramillo, C. A., Spitaleri, G., Manzotti, M., Catania, C., Jordheim, L. P., Pelosi, G., Peters, G. J., Tibaldi, C., Funel, N., Spaggiari, L., de Braud, F., de Pas, T. & Giovannetti, E., 2018, In : Oncotarget. 9, 23, p. 16437-16450 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer: a prospective validation study

Italian Oncological Group of Clinical Research (GOIRC), Tibaldi, C., Camerini, A., Tiseo, M., Mazzoni, F., Barbieri, F., Vittimberga, I., Brighenti, M., Boni, L., Baldini, E., Gilli, A., Honeywell, R., Chartoire, M., Peters, G. J. & Giovannetti, E., 27 Nov 2018, In : British Journal of Cancer. 119, 11, p. 1326-1331 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Double Trouble: A Case Series on Concomitant Genetic Aberrations in NSCLC

Van Der Steen, N., Mentens, Y., Ramael, M., Leon, L. G., Germonpré, P., Ferri, J., Gandara, D. R., Giovannetti, E., Peters, G. J., Pauwels, P. & Rolfo, C., Jan 2018, In : Clinical Lung Cancer. 19, 1, p. 35-41

Research output: Contribution to journalArticleAcademicpeer-review

Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden

Frampton, A. E., Prado, M. M., López-Jiménez, E., Fajardo-Puerta, A. B., Jawad, Z. A. R., Lawton, P., Giovannetti, E., Habib, N. A., Castellano, L., Stebbing, J., Krell, J. & Jiao, L. R., 2018, In : Oncotarget. 9, 27, p. 19006-19013 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Plasma miR-181a-5p Downregulation Predicts Response and Improved Survival After FOLFIRINOX in Pancreatic Ductal Adenocarcinoma

Meijer, L. L., Garajová, I., Caparello, C., Le Large, T. Y. S., Frampton, A. E., Vasile, E., Funel, N., Kazemier, G. & Giovannetti, E., 1 Nov 2018, In : Annals of Surgery.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Targeting the ribosome biogenesis key molecule fibrillarin to avoid chemoresistance

El Hassouni, B., Sarkisjan, D., Vos, J. C., Giovannetti, E. & Peters, G. J., 3 Dec 2018, In : Current Medicinal Chemistry.

Research output: Contribution to journalArticleAcademicpeer-review

TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression

Ottaviani, S., Stebbing, J., Frampton, A. E., Zagorac, S., Krell, J., de Giorgio, A., Trabulo, S. M., Nguyen, V. T. M., Magnani, L., Feng, H., Giovannetti, E., Funel, N., Gress, T. M., Jiao, L. R., Lombardo, Y., Lemoine, N. R., Heeschen, C. & Castellano, L., 2018, In : Nature Communications. 9, 1, 1845.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The microbiome of pancreatic cancer: from molecular diagnostics to new therapeutic approaches to overcome chemoresistance caused by metabolic inactivation of gemcitabine

Choy, A. T. F., Carnevale, I., Coppola, S., Meijer, L. L., Kazemier, G., Zaura, E., Deng, D. & Giovannetti, E., 2018, In : Expert review of molecular diagnostics. 18, 12, p. 1005-1009

Research output: Contribution to journalArticleAcademicpeer-review

2017

A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer

Coppola, S., Carnevale, I., Danen, E. H. J., Peters, G. J., Schmidt, T., Assaraf, Y. G. & Giovannetti, E., 1 Mar 2017, In : Drug Resistance Updates. 31, p. 43-51 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: A platform for drug testing

Rovithi, M., Avan, A., Funel, N., Leon, L. G., Gomez, V. E., Wurdinger, T., Griffioen, A. W., Verheul, H. M. W. & Giovannetti, E., 17 Mar 2017, In : Scientific Reports. 7, 44686.

Research output: Contribution to journalArticleAcademicpeer-review

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN

Cavazzoni, A., La Monica, S., Alfieri, R., Ravelli, A., Van Der Steen, N., Sciarrillo, R., Madeddu, D., Lagrasta, C. A. M., Quaini, F., Bonelli, M., Fumarola, C., Cretella, D., Digiacomo, G., Tiseo, M., Peters, G. J., Ardizzoni, A., Petronini, P. G. & Giovannetti, E., 8 Aug 2017, In : Oncotarget. 8, 32, p. 53068-53083 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells

Van Der Steen, N., Potze, L., Giovannetti, E., Cavazzoni, A., Ruijtenbeek, R., Rolfo, C., Pauwels, P. & Peters, G. J., 2017, In : American Journal of Cancer Research. 7, 4, p. 816-830 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer

Massihnia, D., Avan, A., Funel, N., Maftouh, M., Van Krieken, A., Granchi, C., Raktoe, R., Boggi, U., Aicher, B., Minutolo, F., Russo, A., Leon, L. G., Peters, G. J. & Giovannetti, E., 6 Jan 2017, In : Journal of Hematology and Oncology. 10, 1, 9.

Research output: Contribution to journalArticleAcademicpeer-review

Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation

Holst, S., Belo, A. I., Giovannetti, E., Van Die, I. & Wuhrer, M., 1 Dec 2017, In : Scientific Reports. 7, 1, 16623.

Research output: Contribution to journalArticleAcademicpeer-review

Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: Clinical evidence and new pharmacological tools

Giovannetti, E., Zucali, P. A., Assaraf, Y. G., Funel, N., Gemelli, M., Stark, M., Thunnissen, E., Hou, Z., Muller, I. B., Struys, E. A., Perrino, M., Jansen, G., Matherly, L. H. & Peters, G. J., 2017, In : Annals of Oncology. 28, 11, p. 2725-2732 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets

Best, M. G., Sol, N., In ‘t Veld, S. G. J. G., Vancura, A., Muller, M., Niemeijer, A. L. N., Fejes, A. V., Tjon Kon Fat, L. A., Huis In ‘t Veld, A. E., Leurs, C., Le Large, T. Y., Meijer, L. L., Kooi, I. E., Rustenburg, F., Schellen, P., Verschueren, H., Post, E., Wedekind, L. E., Bracht, J., Esenkbrink, M. & 33 othersWils, L., Favaro, F., Schoonhoven, J. D., Tannous, J., Meijers-Heijboer, H., Kazemier, G., Giovannetti, E., Reijneveld, J. C., Idema, S., Killestein, J., Heger, M., de Jager, S. C., Urbanus, R. T., Hoefer, I. E., Pasterkamp, G., Mannhalter, C., Gomez-Arroyo, J., Bogaard, H. J., Noske, D. P., Vandertop, W. P., van den Broek, D., Ylstra, B., Nilsson, R. J. A., Wesseling, P., Karachaliou, N., Rosell, R., Lee-Lewandrowski, E., Lewandrowski, K. B., Tannous, B. A., de Langen, A. J., Smit, E. F., van den Heuvel, M. M. & Wurdinger, T., 14 Aug 2017, In : Cancer Cell. 32, 2, p. 238-252.e9

Research output: Contribution to journalArticleAcademicpeer-review

2016

A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1

Giovannetti, E., Leon, L. G., Gomez, V. E., Zucali, P. A., Minutolo, F. & Peters, G. J., 2016, In : Nucleosides, Nucleotides and Nucleic Acids. 35, 10-12, p. 643-651

Research output: Contribution to journalArticleAcademicpeer-review

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer

Van Der Steen, N., Deben, C., Deschoolmeester, V., Wouters, A., Lardon, F., Rolfo, C., Germonpré, P., Giovannetti, E., Peters, G. J. & Pauwels, P., 10 Dec 2016, In : World journal of clinical oncology. 7, 6, p. 425-432 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bioinformatic analysis reveals pancreatic cancer molecular subtypes specific to the tumor and the microenvironment

Le Large, T. Y. S., Prado, M. M., Krell, J., Bijlsma, M. F., Meijer, L. L., Kazemier, G., Frampton, A. E. & Giovannetti, E., 2016, In : Expert review of molecular diagnostics. 16, 7, p. 733-736

Research output: Contribution to journalArticleAcademicpeer-review

cMET Exon 14 Skipping: From the Structure to the Clinic

Van der Steen, N., Giovannetti, E., Pauwels, P., Peters, G. J., Hong, D. S., Cappuzzo, F., Hirsch, F. R. & Rolfo, C., Sep 2016, In : Journal of Thoracic Oncology. 11, 9, p. 1423-1432

Research output: Contribution to journalArticleAcademicpeer-review

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Chemotherapy: A Glimmer of Hope?

Van Der Steen, N., Rolfo, C. D., Pauwels, P., Peters, G. J. & Giovannetti, E., 5 Dec 2016, In : Journal of Clinical Oncology. p. JCO2016701987

Research output: Contribution to journalArticleAcademicpeer-review

Feasibility of cell-free circulating tumor DNA testing for lung cancer

Santarpia, M., Karachaliou, N., González-Cao, M., Altavilla, G., Giovannetti, E. & Rosell, R., 2016, In : Biomarkers in medicine. 10, 4, p. 417-30 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

FOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer

Caparello, C., Meijer, L. L., Garajova, I., Falcone, A., Le Large, T. Y., Funel, N., Kazemier, G., Peters, G. J., Vasile, E. & Giovannetti, E., 21 Aug 2016, In : World Journal of Gastroenterology. 22, 31, p. 6987-7005

Research output: Contribution to journalArticleAcademicpeer-review

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M. & 2,447 othersAit-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Alguel, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Awale, S., Azad, N., Bachetti, T., Backer, J. M., Bae, D-H., Bae, J-S., Bae, O-N., Bae, S. H., Baehrecke, E. H., Baek, S-H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X-Y., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Banhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolome, A., Bassham, D. C., Bassi, M. T., Bast, R. C. . J., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J-F., Beck, G. R. . J., Becker, C., Beckham, J. D., Bedard, P-A., Bednarski, P. J., Begley, T. J., Behl, C., Behrends, C., Behrens, G. M. N., Behrns, K. E., Bejarano, E., Belaid, A., Belleudi, F., Benard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A. S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S. K., Biagosch, C., Bianchi, M. W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S. W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G. A., Blomhoff, H. K., Boada-Romero, E., Boeckler, S., Boes, M., Boesze-Battaglia, K., Boise, L. H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L. M., Botti, J., Bou, G., Bouche, M., Bouchecareilh, M., Boucher, M-J., Boulton, M. E., Bouret, S. G., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N., Braga, V. M. M., Brancolini, C., Braus, G. H., Bravo-San Pedro, J. M., Brennan, L. A., Bresnick, E. H., Brest, P., Bridges, D., Bringer, M-A., Brini, M., Brito, G. C., Brodin, B., Brookes, P. S., Brown, E. J., Brown, K., Broxmeyer, H. E., Bruhat, A., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bryson-Richardson, R. J., Buch, S., Buchan, A. M., Budak, H., Bulavin, D. V., Bultman, S. J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R. E., Burmeister, M., Buetikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G. R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A. B., Caraglia, M., Cardinali, C., Cardoso, S. M., Carew, J. S., Carleton, L. A., Carlin, C. R., Carloni, S., Carlsson, S. R., Carmona-Gutierrez, D., Carneiro, L. A. M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A. I., Cena, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H-J., Chagin, A. S., Chai, C-Y., Chakrabarti, G., Chamilos, G., Chan, E. Y. W., Chan, M. T. V., Chandra, D., Chandra, P., Chang, C-P., Chang, R. C-C., Chang, T. Y., Chatham, J. C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M. E., Cheluvappa, R., Chen, C-J., Chen, G., Chen, G-C., Chen, G., Chen, H., Chen, J. W., Chen, J-K., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S-D., Chen, S., Chen, S. S-L., Chen, W., Chen, W-J., Chen, W. Q., Chen, W., Chen, X., Chen, Y-H., Chen, Y-G., Chen, Y., Chen, Y., Chen, Y., Chen, Y-J., Chen, Y-Q., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C. H. A., Chevet, E., Chi, H. C., Chi, S-G., Chiacchiera, F., Chiang, H-L., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L-S., Chiong, M., Chiu, G. N. C., Cho, D-H., Cho, S-G., Cho, W. C., Cho, Y-Y., Cho, Y-S., Choi, A. M. K., Choi, E-J., Choi, E-K., Choi, J., Choi, M. E., Choi, S-I., Chou, T-F., Chouaib, S., Choubey, D., Choubey, V., Chow, K-C., Chowdhury, K., Chu, C. T., Chuang, T-H., Chun, T., Chung, H., Chung, T., Chung, Y-L., Chwae, Y-J., Cianfanelli, V., Ciarcia, R., Ciechomska, I. A., Ciriolo, M. R., Cirone, M., Claerhout, S., Clague, M. J., Claria, J., Clarke, P. G. H., Clarke, R., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E. M., Cocco, T., Codogno, P., Coers, J., Cohen, E. E. W., Colecchia, D., Coletto, L., Coll, N. S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K. L., Coombs, G. H., Cooper, C. D., Cooper, J. M., Coppens, I., Corasaniti, M. T., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M. D., Corral-Ramos, C., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Costes, S., Coto-Montes, A., Cottet, S., Couve, E., Covey, L. R., Cowart, L. A., Cox, J. S., Coxon, F. P., Coyne, C. B., Cragg, M. S., Craven, R. J., Crepaldi, T., Crespo, J. L., Criollo, A., Crippa, V., Cruz, M. T., Cuervo, A. M., Cuezva, J. M., Cui, T., Cutillas, P. R., Czaja, M. J., Czyzyk-Krzeska, M. F., Dagda, R. K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K. N., Valle, L. D., Dalmasso, G., D'Amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V. M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C. R., Davey, H. M., Davids, L. M., Davila, D., Davis, R. J., Dawson, T. M., Dawson, V. L., Daza, P., de Belleroche, J., de Figueiredo, P., Bressan Queiroz de Figueiredo, R. C., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G. R. Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J-P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D. P., Delage-Mourroux, R., Delbridge, L. M. D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C. J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T. P., Devenish, R. J., Di Bartolomeo, S., Di Daniele, N., Di Domenico, F., Di Nardo, A., Di Paola, S., Di Pietro, A., Di Renzo, L., DiAntonio, A., Diaz-Araya, G., Diaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dickey, C. A., Dickson, R. C., Diederich, M., Digard, P., Dikic, I., Dinesh-Kumar, S. P., Ding, C., Ding, W-X., Ding, Z., Dini, L., Distler, J. H. W., Diwan, A., Djavaheri-Mergny, M., Dmytruk, K., Dobson, R. C. J., Doetsch, V., Dokladny, K., Dokudovskaya, S., Donadelli, M., Dong, X. C., Dong, X., Dong, Z., Donohue, T. M. . J., Doran, K. S., D'Orazi, G., Dorn, G. W. . II., Dosenko, V., Dridi, S., Drucker, L., Du, J., Du, L-L., Du, L., du Toit, A., Dua, P., Duan, L., Duann, P., Dubey, V. K., Duchen, M. R., Duchosal, M. A., Duez, H., Dugail, I., Dumit, V. I., Duncan, M. C., Dunlop, E. A., Dunn, W. A. . J., Dupont, N., Dupuis, L., Duran, R. V., Durcan, T. M., Duvezin-Caubet, S., Duvvuri, U., Eapen, V., Ebrahimi-Fakhari, D., Echard, A., Eckhart, L., Edelstein, C. L., Edinger, A. L., Eichinger, L., Eisenberg, T., Eisenberg-Lerner, A., Eissa, N. T., El-Deiry, W. S., El-Khoury, V., Elazar, Z., Eldar-Finkelman, H., Elliott, C. J. H., Emanuele, E., Emmenegger, U., Engedal, N., Engelbrecht, A-M., Engelender, S., Enserink, J. M., Erdmann, R., Erenpreisa, J., Eri, R., Eriksen, J. L., Erman, A., Escalante, R., Eskelinen, E-L., Espert, L., Esteban-Martinez, L., Evans, T. J., Fabri, M., Fabrias, G., Fabrizi, C., Facchiano, A., Faergeman, N. J., Faggioni, A., Fairlie, W. D., Fan, C., Fan, D., Fan, J., Fang, S., Fanto, M., Fanzani, A., Farkas, T., Faure, M., Favier, F. B., Fearnhead, H., Federici, M., Fei, E., Felizardo, T. C., Feng, H., Feng, Y., Feng, Y., Ferguson, T. A., Fernandez, A. F., Fernandez-Barrena, M. G., Fernandez-Checa, J. C., Fernandez-Lopez, A., Fernandez-Zapico, M. E., Feron, O., Ferraro, E., Ferreira-Halder, C. V., Fesus, L., Feuer, R., Fiesel, F. C., Filippi-Chiela, E. C., Filomeni, G., Fimia, G. M., Fingert, J. 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J., Yu, J-T., Yu, J., Yu, L., Yu, W. H., Yu, X-F., Yu, Z., Yuan, J., Yuan, Z-M., Yue, B. Y. J. T., Yue, J., Yue, Z., Zacks, D. N., Zacksenhaus, E., Zaffaroni, N., Zaglia, T., Zakeri, Z., Zecchini, V., Zeng, J., Zeng, M., Zeng, Q., Zervos, A. S., Zhang, D. D., Zhang, F., Zhang, G., Zhang, G-C., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, J., Zhang, J., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M-Y., Zhang, X., Zhang, X. D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhao, M., Zhao, W-L., Zhao, X., Zhao, Y. G., Zhao, Y., Zhao, Y., Zhao, Y-X., Zhao, Z., Zhao, Z. J., Zheng, D., Zheng, X-L., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, G-Z., Zhou, G., Zhou, H., Zhou, S-F., Zhou, X-J., Zhu, H., Zhu, H., Zhu, W-G., Zhu, W., Zhu, X-F., Zhu, Y., Zhuang, S-M., Zhuang, X., Ziparo, E., Zois, C. E., Zoladek, T., Zong, W-X., Zorzano, A. & Zughaier, S. M., 2016, In : Autophagy. 12, 1, p. 1-222

Research output: Contribution to journalArticleAcademicpeer-review

hENT-1 Expression and Localization Predict Outcome After Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients

Meijer, L. L., Puik, J. R., Peters, G. J., Kazemier, G. & Giovannetti, E., Dec 2016, In : The Oncologist. 21, 12, p. e4

Research output: Contribution to journalArticleAcademicpeer-review

Investigating miRNA-mRNA regulatory networks using crosslinking immunoprecipitation methods for biomarker and target discovery in cancer

Prado, M. M., Frampton, A. E., Giovannetti, E., Stebbing, J., Castellano, L. & Krell, J., Nov 2016, In : Expert review of molecular diagnostics. 16, 11, p. 1155-1162

Research output: Contribution to journalArticleAcademicpeer-review

New developments in the management of non-small-cell lung cancer, focus on rociletinib: what went wrong?

Van Der Steen, N., Caparello, C., Rolfo, C., Pauwels, P., Peters, G. J. & Giovannetti, E., 2016, In : OncoTargets and Therapy. 9, p. 6065-6074

Research output: Contribution to journalArticleAcademicpeer-review

On the pharmacogenetics of non-small cell lung cancer treatment

Santarpia, M., Rolfo, C., Peters, G. J., Leon, L. G. & Giovannetti, E., 3 Mar 2016, In : Expert Opinion on Drug Metabolism and Toxicology. 12, 3, p. 307-317

Research output: Contribution to journalArticleAcademicpeer-review

P2.09: cMET in NSCLC: Expression, Amplification and Mutations: Track: Biology and Pathogenesis

Van Der Steen, N., Rolfo, C., Giovannetti, E., Reclusa, P., Peters, G. J. & Pauwels, P., 2016, In : Journal of Thoracic Oncology. 11, 10S, p. S221-S222

Research output: Contribution to journalArticleAcademicpeer-review

Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective

Ciccolini, J., Serdjebi, C., Peters, G. J. & Giovannetti, E., Jul 2016, In : Cancer Chemotherapy and Pharmacology. 78, 1, p. 1-12

Research output: Contribution to journalArticleAcademicpeer-review

Prognostic and Predictive Roles of Thymidylate Synthase Expression in Lung Cancer: The Debate Is Still Open

Giovannetti, E., Zucali, P. A., Rolfo, C., Assaraf, Y. G. & Peters, G. J., 10 Feb 2016, In : Journal of Clinical Oncology. 34, 5, p. 511-+

Research output: Contribution to journalArticleAcademicpeer-review

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies

Frampton, A. E., Krell, J., Prado, M. M., Gall, T. M. H., Abbassi-Ghadi, N., Blanco, G. D. V., Funel, N., Giovannetti, E., Castellano, L., Basyouny, M., Habib, N. A., Kaltsidis, H., Vlavianos, P., Stebbing, J. & Jiao, L. R., 10 May 2016, In : Oncotarget. 7, 19, p. 28556-28569

Research output: Contribution to journalArticleAcademicpeer-review

Recent developments in the use of immunotherapy in non-small cell lung cancer

Santarpia, M., Giovannetti, E., Rolfo, C., Karachaliou, N., Gonzalez-Cao, M., Altavilla, G. & Rosell, R., 2016, In : EXPERT REVIEW OF RESPIRATORY MEDICINE. 10, 7, p. 781-798

Research output: Contribution to journalArticleAcademicpeer-review

Role of Akt signaling in resistance to DNA-targeted therapy

Avan, A., Narayan, R., Giovannetti, E. & Peters, G. J., 2016, In : World journal of clinical oncology. 7, 5, p. 352-369 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy-Letter

Leon, L. G., Funel, N., Peters, G. J., Avan, A., Vistoli, F., Boggi, U. & Giovannetti, E., 15 May 2016, In : Clinical Cancer Research. 22, 10, p. 2594-2594

Research output: Contribution to journalArticleAcademicpeer-review

The potential of neurotrophic tyrosine kinase (NTRK) inhibitors for treating lung cancer

Passiglia, F., Caparica, R., Giovannetti, E., Giallombardo, M., Listi, A., Diana, P., Cirrincione, G., Caglevic, C., Raez, L. E., Russo, A. & Rolfo, C., 2 Apr 2016, In : Expert Opinion on Investigational Drugs. 25, 4, p. 385-392

Research output: Contribution to journalArticleAcademicpeer-review

Tissue distribution of Crizotinib and Gemcitabine combination in a patient-derived orthotopic mouse model of pancreatic cancer

Honeywell, RJ., Avan, A., Giovannetti, E. & Peters, GJ., 2016, In : ADMET & DMPK. 4, p. 327-334

Research output: Contribution to journalArticleAcademicpeer-review

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models

Sciarrillo, R., Wojtuszkiewicz, A., Kooi, I. E., Gómez, V. E., Boggi, U., Jansen, G., Kaspers, G-J., Cloos, J. & Giovannetti, E., 9 Dec 2016, In : Journal of Visualized Experiments. 118

Research output: Contribution to journalArticleAcademic

2015

Circulating microRNAs as diagnostic biomarkers for pancreatic cancer

Le Large, T. Y. S., Meijer, L. L., Prado, M. M., Kazemier, G., Frampton, A. E. & Giovannetti, E., 2015, In : Expert review of molecular diagnostics. 15, 12, p. 1525-1529

Research output: Contribution to journalArticleAcademicpeer-review

C-MET as a target for personalized therapy

Garajova, I., Giovannetti, E., Biasco, G. & Peters, G. J., 2015, In : Translational Oncogenomics. 7, Suppl 1, p. 13-21

Research output: Contribution to journalArticleAcademicpeer-review

Cytochrome P450 1B1 (CYP1B1) polymorphisms are associated with clinical outcome of docetaxel in non-small cell lung cancer (NSCLC) patients

Vasile, E., Tibaldi, C., Leon, G. L., D'Incecco, A. & Giovannetti, E., 2015, In : Journal of Cancer Research and Clinical Oncology. 141, 7, p. 1189-1194

Research output: Contribution to journalArticleAcademicpeer-review