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Review article

Anaplastic lymphoma kinase inhibition in metastatic non-small cell lung cancer: Clinical impact of alectinib

Muller, I. B., De Langen, A. J., Giovannetti, E. & Peters, G. J., 13 Sep 2017, In : OncoTargets and Therapy. 10, p. 4535-4541 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Combined exosomal RNA and circulating tumor DNA for epidermal growth factor mutation detection in non-small cell lung cancer

Lazzari, C., Gregorc, V., Cangi, M. G., Giovannetti, E., Bulotta, A. & Santarpia, M., 2018, In : Journal of Thoracic Disease. 10, p. S4023-S4027

Research output: Contribution to journalReview articleAcademicpeer-review

Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract

Roos, E., Soer, E. C., Klompmaker, S., Meijer, L. L., Besselink, M. G., Giovannetti, E., Heger, M., Kazemier, G., Klümpen, H. J., Takkenberg, R. B., Wilmink, H., Würdinger, T., Dijk, F., van Gulik, T. M., Verheij, J. & van de Vijver, M. J., 1 Aug 2019, In : Critical Reviews in Oncology/Hematology. 140, p. 8-16

Research output: Contribution to journalReview articleAcademicpeer-review

Drug resistance in pancreatic cancer: Impact of altered energy metabolism

Grasso, C., Jansen, G. & Giovannetti, E., 1 Jun 2017, In : Critical Reviews in Oncology/Hematology. 114, p. 139-152 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers

Moosavi, F., Giovannetti, E., Saso, L. & Firuzi, O., 17 Nov 2019, In : Critical Reviews in Clinical Laboratory Sciences. 56, 8, p. 533-566 34 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Key biological processes driving metastatic spread of pancreatic cancer as identified by multi-omics studies

Le Large, T. Y. S., Bijlsma, M. F., Kazemier, G., van Laarhoven, H. W. M., Giovannetti, E. & Jimenez, C. R., 1 Jun 2017, In : Seminars in Cancer Biology. 44, p. 153-169 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Light and shadow on innovative clinical trial designs: reflections from the EORTC-PAMM course on ‘preclinical and early-phase clinical pharmacology’

Leonetti, A., Boyd, L., Giuliani, J., Giovannetti, E., Garajová, I. & on Behalf of the EORTC PAMM Group, 2 Nov 2019, In : Expert Review of Clinical Pharmacology. 12, 11, p. 1033-1036 4 p.

Research output: Contribution to journalReview articleAcademicpeer-review

MiRNA profiling for diagnosis, prognosis and stratification of cancer treatment in cholangiocarcinoma

Puik, J. R., Meijer, L. L., Le Large, T. Y. S., Prado, M. M., Frampton, A. E., Kazemier, G. & Giovannetti, E., 1 Sep 2017, In : Pharmacogenomics. 18, 14, p. 1343-1358 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

miRNAs: micro-managers of anticancer combination therapies

van Beijnum, J. R., Giovannetti, E., Poel, D., Nowak-Sliwinska, P. & Griffioen, A. W., May 2017, In : Angiogenesis. 20, 2, p. 269-285 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Never let it go: Stopping key mechanisms underlying metastasis to fight pancreatic cancer

Giovannetti, E., van der Borden, C. L., Frampton, A. E., Ali, A., Firuzi, O. & Peters, G. J., 1 Jun 2017, In : Seminars in Cancer Biology. 44, p. 43-59 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Noncoding RNAs emerging as novel biomarkers in pancreatic cancer

Garajová, I., Balsano, R., Tommasi, C. & Giovannetti, E., 2018, In : Current pharmaceutical design. 24, 39, p. 4601-4604

Research output: Contribution to journalReview articleAcademicpeer-review

Notch pathway in small-cell lung cancer: from preclinical evidence to therapeutic challenges

Leonetti, A., Facchinetti, F., Minari, R., Cortellini, A., Rolfo, C. D., Giovannetti, E. & Tiseo, M., 1 Jun 2019, In : Cellular Oncology. 42, 3, p. 261-273 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Novel targeted strategies to overcome resistance in small-cell lung cancer: focus on PARP inhibitors and rovalpituzumab tesirine

van den Borg, R., Leonetti, A., Tiseo, M., Giovannetti, E. & Peters, G. J., 3 Jun 2019, In : Expert Review of Anticancer Therapy. 19, 6, p. 461-471 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer

Giovannetti, E., Mey, V., Nannizzi, S., Pasqualetti, G., Del Tacca, M. & Danesi, R., 1 Jun 2006, In : Molecular Cancer Therapeutics. 5, 6, p. 1387-1395 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Primary and metastatic brain cancer genomics and emerging biomarkers for immunomodulatory cancer treatment

Passiglia, F., Caglevic, C., Giovannetti, E., Pinto, J. A., Manca, P., Taverna, S., Listì, A., Gil-Bazo, I., Raez, L. E., Russo, A. & Rolfo, C., 2018, In : Seminars in Cancer Biology. 52, Pt 2, p. 259-268 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Proton-coupled folate transporter as a biomarker of outcome to treatment for pleural mesothelioma

Petri, G. L., Cascioferro, S., Parrino, B., Peters, G. J., Diana, P. & Giovannetti, E., 2018, In : Pharmacogenomics. 19, 10, p. 811-814 4 p.

Research output: Contribution to journalReview articleAcademicpeer-review

PTEN alterations as a potential mechanism for tumor cell escape from PD-1/PD-L1 inhibition

Cretella, D., Digiacomo, G., Giovannetti, E. & Cavazzoni, A., 1 Sep 2019, In : Cancers. 11, 9, 1318.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer

Leonetti, A., Sharma, S., Minari, R., Perego, P., Giovannetti, E. & Tiseo, M., 29 Oct 2019, In : British Journal of Cancer. 121, 9, p. 725-737 13 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Spotlight on ceritinib in the treatment of ALK+ NSCLC: Design, development and place in therapy

Santarpia, M., Daffinà, M. G., D’Aveni, A., Marabello, G., Liguori, A., Giovannetti, E., Karachaliou, N., Cao, M. G., Rosell, R. & Altavilla, G., 5 Jul 2017, In : Drug Design, Development and Therapy. 11, p. 2047-2063 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance

Parrino, B., Schillaci, D., Carnevale, I., Giovannetti, E., Diana, P., Cirrincione, G. & Cascioferro, S., 2019, In : European Journal of Medicinal Chemistry. 161, p. 154-178 25 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies

el Hassouni, B., Granchi, C., Vallés-Martí, A., Supadmanaba, I. G. P., Bononi, G., Tuccinardi, T., Funel, N., Jimenez, C. R., Peters, G. J., Giovannetti, E. & Minutolo, F., 21 Aug 2019, In : Seminars in Cancer Biology.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

To Combine or Not Combine: Drug Interactions and Tools for Their Analysis. Reflections from the EORTC-PAMM Course on Preclinical and Early-phase Clinical Pharmacology

El Hassouni, B., Mantini, G., Li Petri, G., Capula, M., Boyd, L., Weinstein, H. N. W., Vallés-Marti, A., Kouwenhoven, M. C. M., Giovannetti, E., Westerman, B. A., Peters, G. J. & EORTC PAMM Group, 1 Jan 2019, In : Anticancer Research. 39, 7, p. 3303-3309 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Tumor microbiome: Pancreatic cancer and duodenal fluids contain multitudes, ...but do they contradict themselves?

Meijer, L. L., Zwart, E. S., Brandt, B. W., Mebius, R., Deng, D., Giovannetti, E., Zaura, E. & Kazemier, G., Dec 2019, In : Critical Reviews in Oncology/Hematology. 144

Research output: Contribution to journalReview articleAcademicpeer-review

WDR48 (WD repeat domain 48)

Olazabal-Herrero, A., Peters, G. J., Giovannetti, E. & Rodriguez, J. A., 2018, In : Atlas of Genetics and Cytogenetics in Oncology and Haematology. 22, 2, p. 44-50

Research output: Contribution to journalReview articleAcademicpeer-review