Esther Drent

20152019
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Research Output 2015 2019

Combined CD28 and 4-1BB costimulation potentiates affinity-tuned chimeric antigen receptor-engineered t cells

Drent, E., Poels, R., Ruiter, R., van de Donk, N. W. C. J., Zweegman, S., Yuan, H., de Bruijn, J., Sadelain, M., Lokhorst, H. M., Groen, R. W. J., Mutis, T. & Themeli, M., 2019, In : Clinical Cancer Research. 25, 13, p. 4014-4025

Research output: Contribution to journalArticleAcademicpeer-review

Feasibility of controlling CD38-CAR T cell activity with a Tet-on inducible CAR design

Drent, E., Poels, R., Mulders, M. J., van de Donk, N. W. C. J., Themeli, M., Lokhorst, H. M. & Mutis, T., 2018, In : PLoS ONE. 13, 5, p. e0197349

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization

Drent, E., Themeli, M., Poels, R., de Jong-Korlaar, R., Yuan, H., de Bruijn, J., Martens, A. C. M., Zweegman, S., van de Donk, N. W. C. J., Groen, R. W. J., Lokhorst, H. M. & Mutis, T., 2 Aug 2017, In : Molecular Therapy. 25, 8, p. 1946-1958 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Drent, E., Groen, R. W. J., Noort, W. A., Themeli, M., van Bueren, J. J. L., Parren, P. W. H. I., Kuball, J., Sebestyen, Z., Yuan, H., de Bruijn, J., van de Donk, N. W. C. J., Martens, A. C. M., Lokhorst, H. M. & Mutis, T., May 2016, In : Haematologica. 101, 5, p. 616-625

Research output: Contribution to journalArticleAcademicpeer-review

Chimere antigeenreceptoren als immuuntherapie voor hematologische maligniteiten

Drent, E., van de Donk, N. W. C. J., Lokhorst, H. M. & Mutis, T., 2015, In : Nederlands Tijdschrift voor Hematologie. 12, 8, p. 303-312

Research output: Contribution to journalArticleProfessional