20082019
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Research Output 2008 2019

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Article
2019

Measurement of plasma cell-free mitochondrial tumor DNA improves detection of glioblastoma in patient-derived orthotopic xenograft models

Mair, R., Mouliere, F., Smith, C. G., Chandrananda, D., Gale, D., Marass, F., Tsui, D. W. Y., Massie, C. E., Wright, A. J., Watts, C., Rosenfeld, N. & Brindle, K. M., 1 Jan 2019, In : Cancer Research. 79, 1, p. 220-230 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

Ahlborn, L. B., Tuxen, I. V., Mouliere, F., Kinalis, S., Schmidt, A. Y., Rohrberg, K. S., Santoni-Rugiu, E., Nielsen, F. C., Lassen, U., Yde, C. W., Oestrup, O. & Mau-Sorensen, M., 24 Aug 2018, In : Oncotarget. 9, 66, p. 32570-32579 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients

Mouliere, F., Mair, R., Chandrananda, D., Marass, F., Smith, C. G., Su, J., Morris, J., Watts, C., Brindle, K. M. & Rosenfeld, N., 1 Dec 2018, In : Embo Molecular Medicine. 10, 12, e9323.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Enhanced detection of circulating tumor DNA by fragment size analysis

Mouliere, F., Chandrananda, D., Piskorz, A. M., Moore, E. K., Morris, J., Ahlborn, L. B., Mair, R., Goranova, T., Marass, F., Heider, K., Wan, J. C. M., Supernat, A., Hudecova, I., Gounaris, I., Ros, S., Jimenez-Linan, M., Garcia-Corbacho, J., Patel, K., Østrup, O., Murphy, S. & 17 othersEldridge, M. D., Gale, D., Stewart, G. D., Burge, J., Cooper, W. N., van der Heijden, M. S., Massie, C. E., Watts, C., Corrie, P., Pacey, S., Brindle, K. M., Baird, R. D., Mau-Sørensen, M., Parkinson, C. A., Smith, C. G., Brenton, J. D. & Rosenfeld, N., 7 Nov 2018, In : Science Translational Medicine. 10, 466

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Association of Plasma and Urinary Mutant DNA with Clinical Outcomes in Muscle Invasive Bladder Cancer

Patel, K. M., Van Der Vos, K. E., Smith, C. G., Mouliere, F., Tsui, D., Morris, J. A., Chandrananda, D., Marass, F., Van Den Broek, D., Neal, D. E., Gnanapragasam, V. J., Forshew, T., Van Rhijn, B. W., Massie, C. E., Rosenfeld, N. & Van Der Heijden, M. S., 1 Dec 2017, In : Scientific Reports. 7, 1, 5554.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Selecting Short DNA Fragments In Plasma Improves Detection Of Circulating Tumour DNA

Mouliere, F., Piskorz, A. M., Chandrananda, D., Moore, E., Morris, J., Smith, C. G., Goranova, T., Heider, K., Mair, R., Supernat, A., Gounaris, I., Ros, S., Wan, J. C. M., Jimenez-Linan, M., Gale, D., Brindle, K., Massie, C. E., Parkinson, C. A., Brenton, J. D. & Rosenfeld, N., 2017, In : Biorxiv.

Research output: Contribution to journalArticleAcademic

2016

A phylogenetic latent feature model for clonal deconvolution

Marass, F., Mouliere, F., Yuan, K., Rosenfeld, N. & Markowetz, F., 1 Dec 2016, In : Annals of Applied Statistics. 10, 4, p. 2377-2404 28 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Circulating DNA as a strong multimarker prognostic tool for metastatic colorectal cancer patient management care

El Messaoudi, S., Mouliere, F., Du Manoir, S., Bascoul-Mollevi, C., Gillet, B., Nouaille, M., Fiess, C., Crapez, E., Bibeau, F., Theillet, C., Mazard, T., Pezet, D., Mathonnet, M., Ychou, M. & Thierry, A. R., 15 Jun 2016, In : Clinical Cancer Research. 22, 12, p. 3067-3077 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015

Circulating tumor-derived DNA is shorter than somatic DNA in plasma

Mouliere, F. & Rosenfeld, N., 17 Mar 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 11, p. 3178-3179 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Detection of genetic alterations by nucleic acid analysis: Use of PCR and mass spectroscopy-based methods

Mouliere, F., Thierry, A. R. & Larroque, C., 1 Jan 2015, In : Advances in Predictive, Preventive and Personalised Medicine. 5, p. 89-111 23 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

Thierry, A. R., Mouliere, F., El Messaoudi, S., Mollevi, C., Lopez-Crapez, E., Rolet, F., Gillet, B., Gongora, C., Dechelotte, P., Robert, B., Del Rio, M., Lamy, P. J., Bibeau, F., Nouaille, M., Loriot, V., Jarrousse, A. S., Molina, F., Mathonnet, M., Pezet, D. & Ychou, M., 1 Jan 2014, In : Nature Medicine. 20, 4, p. 430-435 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multi-marker analysis of circulating cell-free DNA toward personalized medicine for colorectal cancer

Mouliere, F., El Messaoudi, S., Pang, D., Dritschilo, A. & Thierry, A. R., 1 Jan 2014, In : Molecular oncology. 8, 5, p. 927-941 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2013

Circulating cell-free DNA from colorectal cancer patients may reveal high KRAS or BRAF mutation load

Mouliere, F., Messaoudi, S. E., Gongora, C., Guedj, A. S., Robert, B., del Rio, M., Molina, F., Lamy, P. J., Lopez-Crapez, E., Mathonnet, M., Ychou, M., Pezet, D. & Thierry, A. R., 1 Jan 2013, In : Translational Oncology. 6, 3, p. 319-328 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2012
2011

High fragmentation characterizes tumour-derived circulating DNA

Mouliere, F., Robert, B., Peyrotte, E., Del Rio, M., Ychou, M., Molina, F., Gongora, C. & Thierry, A. R., 12 Sep 2011, In : PLoS ONE. 6, 9, e23418.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2010

Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts

Thierry, A. R., Mouliere, F., Gongora, C., Ollier, J., Robert, B., Ychou, M., del Rio, M. & Molina, F., 21 May 2010, In : Nucleic Acids Research. 38, 18, p. 6159-6175 17 p., gkq421.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2008

Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats

Arancibia, S., Silhol, M., Moulière, F., Meffre, J., Höllinger, I., Maurice, T. & Tapia-Arancibia, L., 1 Sep 2008, In : Neurobiology of Disease. 31, 3, p. 316-326 11 p.

Research output: Contribution to journalArticleAcademicpeer-review