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Research Output 2009 2019

2019

6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling

Kurakula, K., Sun, X-Q., Happé, C., da Silva Goncalves Bos, D., Szulcek, R., Schalij, I., Wiesmeijer, K. C., Lodder, K., Tu, L., Guignabert, C., de Vries, C. J. M., de Man, F. S., Noordegraaf, A. V., Ten Dijke, P., Goumans, M-J. & Bogaard, H. J., 4 Jul 2019, In : The European respiratory journal.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of combined angiotensin II receptor antagonism and neprilysin inhibition in experimental pulmonary hypertension and right ventricular failure

Andersen, S., Axelsen, J. B., Ringgaard, S., Nyengaard, J. R., Hyldebrandt, J. A., Bogaard, H. J., de Man, F. S., Nielsen-Kudsk, J. E. & Andersen, A., 1 Jan 2019, In : International Journal of Cardiology.

Research output: Contribution to journalArticleAcademicpeer-review

ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension

Grünig, E., Eichstaedt, C., Barberà, J-A., Benjamin, N., Blanco, I., Bossone, E., Cittadini, A., Coghlan, G., Corris, P., D'Alto, M., D'Andrea, A., Delcroix, M., de Man, F., Gaine, S., Ghio, S., Gibbs, S., Gumbiene, L., Howard, L. S., Johnson, M., Jurevičienė, E. & 16 othersKiely, D. G., Kovacs, G., MacKenzie, A., Marra, A. M., McCaffrey, N., McCaughey, P., Naeije, R., Olschewski, H., Pepke-Zaba, J., Reis, A., Santos, M., Saxer, S., Tulloh, R. M., Ulrich, S., Vonk Noordegraaf, A. & Peacock, A. J., Feb 2019, In : The European respiratory journal. 53, 2

Research output: Contribution to journalArticleAcademicpeer-review

Highlights from the ERS International Congress 2018: Assembly 13 - Pulmonary Vascular Diseases

Ramjug, S., Adão, R., Lewis, R., Coste, F., de Man, F., Jimenez, D., Sitbon, O., Delcroix, M. & Vonk-Noordegraaf, A., 2019, In : ERS Monograph. 5, 1, 00202-2018.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension

Rol, N., de Raaf, M. A., Sun, X. Q., Kuiper, V. P., da Silva Gonçalves Bos, D., Happé, C., Kurakula, K., Dickhoff, C., Thuillet, R., Tu, L., Guignabert, C., Schalij, I., Lodder, K., Pan, X., Herrmann, F. E., van Nieuw Amerongen, G. P., Koolwijk, P., Vonk-Noordegraaf, A., de Man, F. S., Wollin, L. & 3 othersGoumans, M-J., Szulcek, R. & Bogaard, H. J., 2019, In : Cardiovascular Research. 115, 2, p. 432-439

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone

Andersen, S., Birkmose Axelsen, J., Ringgaard, S., Randel Nyengaard, J., Holm Nielsen, S., Genovese, F., Asser Karsdal, M., Adler Hyldebrandt, J., Brandt Sørensen, C., de Man, F. S., Jan Bogaard, H., Erik Nielsen-Kudsk, J. & Andersen, A., Apr 2019, In : Pulmonary Circulation. 9, 2, p. 204589401984865

Research output: Contribution to journalArticleAcademicpeer-review

Pulmonary Hypertension in a Nonreferral Setting in the Netherlands: Incidence and Patient Characteristics in the Optics Registry

Jansen, S., in 't Veld, A. E. H., Tolen, P. C. G., Jacobs, W., Grotjohan, H. P., Waskowsky, W., van der Maten, J., van der Weerdt, A., Hoekstra, R., Overbeek, M., Mollema, S., el Bouazzaoui, L. H. H., Vriend, J., Roorda, M., de Nooijer, R., van der Lee, I., Voogel, A. J., Peels, C., Aerts, J. G., Van de Ven, M. & 3 othersDe Man, F., Noordegraaf, A. V. & Bogaard, H. J., 2019, In : American Journal of Respiratory and Critical Care Medicine. 199

Research output: Contribution to journalMeeting AbstractAcademic

Right Ventricular Fibrosis

Andersen, S., Nielsen-Kudsk, J. E., Vonk Noordegraaf, A. & de Man, F. S., 8 Jan 2019, In : Circulation. 139, 2, p. 269-285 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

The right treatment for the right ventricle

Groeneveldt, J. A., de Man, F. S. & Westerhof, B. E., Sep 2019, In : Current opinion in pulmonary medicine. 25, 5, p. 410-417 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The unknown pathophysiological relevance of right ventricular hypertrophy in pulmonary arterial hypertension

de Man, F. S., Louis Handoko, M. & Vonk-Noordegraaf, A., 2019, In : European Respiratory Journal. 53, 4

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
2018

3'-Deoxy-3'-[18F]Fluorothymidine Positron Emission Tomography Depicts Heterogeneous Proliferation Pathology in Idiopathic Pulmonary Arterial Hypertension Patient Lung

Ashek, A., Spruijt, O. A., Harms, H. J., Lammertsma, A. A., Cupitt, J., Dubois, O., Wharton, J., Dabral, S., Pullamsetti, S. S., Huisman, M. C., Frings, V., Boellaard, R., de Man, F. S., Botros, L., Jansen, S., Vonk Noordegraaf, A., Wilkins, M. R., Bogaard, H. J. & Zhao, L., 2018, In : Circulation. Cardiovascular imaging. 11, 8, p. e007402

Research output: Contribution to journalArticleAcademicpeer-review

ACE2 as therapy for pulmonary arterial hypertension: the good outweighs the bad

Guignabert, C., de Man, F. & Lombès, M., 1 Jun 2018, In : The European respiratory journal. 51, 6

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Boosting small heat shock proteins lowers cardiomyocyte passive stiffness in experimental heart failure with preserved ejection fraction

Waddingham, M. T., Dal Canto, E., Bos, D. D. S. G., Sequeria, V., Van Heerebeek, L., Kuster, D. W. D., De Man, F. S., Van Der Velden, J., Handoko, M. L., Eringa, E. C. & Paulus, W. J., May 2018, In : European Journal of Heart Failure. 20, p. 24-24

Research output: Contribution to journalMeeting AbstractAcademic

Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension

Da Silva Gonçalves Bós, D., Van Der Bruggen, C. E. E., Kurakula, K., Sun, X. Q., Casali, K. R., Casali, A. G., Rol, N., Szulcek, R., Dos Remedios, C., Guignabert, C., Tu, L., Dorfmüller, P., Humbert, M., Wijnker, P. J. M., Kuster, D. W. D., Van Der Velden, J., Goumans, M. J., Bogaard, H. J., Vonk-Noordegraaf, A., De Man, F. S. & 1 othersHandoko, M. L., 1 Jan 2018, In : Circulation. 137, 9, p. 910-924 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease (Biophysical Reviews, (2017), 9, 4, (431-441), 10.1007/s12551-017-0305-3)

dos Remedios, C. G., Lal, S. P., Li, A., McNamara, J., Keogh, A., Macdonald, P. S., Cooke, R., Ehler, E., Knöll, R., Marston, S. B., Stelzer, J., Granzier, H., Bezzina, C., van Dijk, S., De Man, F. S., Stienen, G. J. M., Odeberg, J., Pontén, F., Linke, W. A. & van der Velden, J., 1 Jun 2018, In : Biophysical Reviews. 10, 3, 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Effects of combined angiotensin II receptor antagonism and neprilysin inhibition in pulmonary arterial hypertension and right heart failure

Andersen, S., Andersen, A., Axelsen, J. B., Ringgard, S., Nyengaard, J. R., Hyldebrandt, J. A., Bogaard, H. J., De Man, F. S. & Nielsen-Kudsk, J. E., Aug 2018, In : European Heart Journal. 39, p. 633-634

Research output: Contribution to journalMeeting AbstractAcademic

The effect of Monoamine oxidase A inhibition on experimentally induced pulmonary arterial hypertension

Sun, X-Q., Peters, E., Schalij, I., Andersen, S., Bos, D. D. S. G., Vonk-Noordegraaf, A., De Man, F. S., Van der Laarse, W. & Bogaard, H. J., 15 Sep 2018, In : European Respiratory Journal. 52

Research output: Contribution to journalMeeting AbstractAcademic

2017

A focus on the greatness of the lesser circulation: Spotlight issue on the right ventricle

De Man, F. S. & La Gerche, A., 1 Oct 2017, In : Cardiovascular Research. 113, 12, p. 1421-1422 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Neurohormonal activation in pulmonary arterial hypertension

da Silva Goncalves Bos, D., 2017, 156 p.

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

Open Access

Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension

da Silva Gonçalves Bos, D., Happé, C., Schalij, I., Pijacka, W., Paton, J. F. R., Guignabert, C., Tu, L., Thuillet, R., Bogaard, H. J., van Rossum, A. C., Vonk-Noordegraaf, A., de Man, F. S. & Handoko, M. L., 2017, In : JACC: Basic to Translational Science. 2, 1, p. 22-35 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

RV pressure overload: from hypertrophy to failure

van der Bruggen, C. E. E., Tedford, R. J., Handoko, M. L., van der Velden, J. & de Man, F. S., 1 Oct 2017, In : Cardiovascular Research. 113, 12, p. 1423-1432

Research output: Contribution to journalArticleAcademicpeer-review

The effect of 6-mercaptopurine treatment on experimentally induced pulmonary arterial hypertension

Sun, X-Q., Kurakula, K., Happe, C., Bos, D. D. S. G., Schalij, I., Vonk-Noordegraaf, A., de Man, F. S., Bogaard, H-J. & Goumans, M-J., 1 Sep 2017, In : European Respiratory Journal. 50

Research output: Contribution to journalMeeting AbstractAcademic

The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease

dos Remedios, C. G., Lal, S. P., Li, A., McNamara, J., Keogh, A., Macdonald, P. S., Cooke, R., Ehler, E., Knöll, R., Marston, S. B., Stelzer, J., Granzier, H., Bezzina, C., van Dijk, S., De Man, F., Stienen, G. J. M., Odeberg, J., Pontén, F., Linke, W. & van der Velden, J., 1 Aug 2017, In : Biophysical Reviews. 9, 4, p. 431-441 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Use of β-Blockers in Pulmonary Hypertension

Perros, F., De Man, F. S., Bogaard, H. J., Antigny, F., Simonneau, G., Bonnet, S., Provencher, S., Galiè, N. & Humbert, M., 1 Apr 2017, In : Circulation: Heart Failure. 10, 4, e003703.

Research output: Contribution to journalReview articleAcademicpeer-review

Vascular remodelling in the pulmonary circulation after major lung resection

Rol, N., Happe, C., Belien, J. A. M., de Man, F. S., Westerhof, N., Vonk-Noordegraaf, A., Grunberg, K. & Bogaard, H. J., 1 Aug 2017, In : European Respiratory Journal. 50, 2, 1700806.

Research output: Contribution to journalArticleAcademicpeer-review

2016

A critical appraisal of transpulmonary and diastolic pressure gradients

Handoko, M. L., De Man, F. S., Oosterveer, F. P. T., Bogaard, H-J., Vonk-Noordegraaf, A. & Westerhof, N., Sep 2016, In : Physiological Reports. 4, 17, e12910.

Research output: Contribution to journalArticleAcademicpeer-review

Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension A View on the Right Ventricle

van der Bruggen, C. E., Happe, C. M., Dorfmueller, P., Trip, P., Spruijt, O. A., Rol, N., Hoevenaars, F. P., Houweling, A. C., Girerd, B., Marcus, J. T., Mercier, O., Humbert, M., Handoko, M. L., van der Velden, J., Noordegraaf, A. V., Bogaard, H. J., Goumans, M-J. & de Man, F. S., 3 May 2016, In : Circulation. 133, 18, p. 1747-1760

Research output: Contribution to journalArticleAcademicpeer-review

Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage

Szulcek, R., Happe, C. M., Rol, N., Fontijn, R. D., Dickhoff, C., Hartemink, K. J., Grunberg, K., Tu, L., Timens, W., Nossent, G. D., Paul, M. A., Leyen, T. A., Horrevoets, A. J., de Man, F. S., Guignabert, C., Yu, P. B., Vonk-Noordegraaf, A., van Nieuw Amerongen, G. & Bogaard, H. J., 15 Jun 2016, In : American Journal of Respiratory and Critical Care Medicine. 193, 12, p. 1410-1420

Research output: Contribution to journalArticleAcademicpeer-review

Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats

Happe, C. M., de Raaf, M. A., Rol, N., Schalij, I., Vonk Noordegraaf, A., Westerhof, N., Voelkel, N. F., de Man, F. S. & Bogaard, H. J., 1 Jun 2016, In : American Journal of Physiology. Lung Cellular and Molecular Physiology. 310, 11, p. L1088-L1097

Research output: Contribution to journalArticleAcademicpeer-review

Reduced force of diaphragm muscle fibers in patients with chronic thromboembolic pulmonary hypertension

Manders, E., Bonta, P. I., Kloek, J. J., Symersky, P., Bogaard, H-J., Hooijman, P. E., Jasper, J. R., Malik, F. I., Stienen, G., Vonk-Noordegraaf, A., de Man, F. S. & Ottenheijm, C. A. C., 1 Jul 2016, In : American Journal of Physiology. Lung Cellular and Molecular Physiology. 311, 1, p. L20-L28

Research output: Contribution to journalArticleAcademicpeer-review

Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension Relative Contribution of Fibrosis and Myofibril Stiffness

Rain, S., Andersen, S., Najafi, A., Schultz, J. G., Bos, D. D. S. G., Handoko, M. L., Bogaard, H-J., Vonk-Noordegraaf, A., Andersen, A., van der Velden, J., Ottenheijm, C. A. C. & de Man, F. S., Jul 2016, In : Circulation. Heart failure. 9, 7, e002636.

Research output: Contribution to journalArticleAcademicpeer-review

The effect of perioperative insulin treatment on cardiodepression in mild adiposity in mice

Boly, C. A., Eringa, E. C., Bouwman, R. A., van den Akker, R. F. P., de Man, F. S., Schalij, I., Loer, S. A., Boer, C. & van den Brom, C. E., 20 Sep 2016, In : Cardiovascular Diabetology. 15, 135.

Research output: Contribution to journalArticleAcademicpeer-review

Tyrosine kinase inhibitor BIBF1000 does not hamper right ventricular pressure adaptation in rats

de Raaf, M. A., Herrmann, F. E., Schalij, I., de Man, F. S., Vonk-Noordegraaf, A., Guignabert, C., Wollin, L. & Bogaard, H. J., Sep 2016, In : American Journal of Physiology. Heart and Circulatory Physiology. 311, 3, p. H604-H612

Research output: Contribution to journalArticleAcademicpeer-review

2015

beta-blockers in pulmonary arterial hypertension: evolving concepts of right heart failure

de Man, F. S. & Handoko, M. L., 2015, In : European Respiratory Journal. 46, 3, p. 619-621

Research output: Contribution to journalArticleAcademicpeer-review

Characteristics of Pulmonary Arterial Hypertension in Affected Carriers of a Mutation Located in the Cytoplasmic Tail of Bone Morphogenetic Protein Receptor Type 2

Girerd, B., Coulet, F., Jais, X., Eyries, M., van der Bruggen, C. E. E., de Man, F. S., Houweling, A. C., Dorfmueller, P., Savale, L., Sitbon, O., Vonk-Noordegraaf, A., Soubrier, F., Simonneau, G., Humbert, M. & Montani, D., 2015, In : Chest. 147, 5, p. 1385-1394

Research output: Contribution to journalArticleAcademicpeer-review

Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency

Ruiter, G., Manders, E., Happe, C. M., Schalij, I., Groepenhoff, H., Howard, L. S., Wilkins, M. R., Bogaard, H. J., Westerhof, N., van der Laarse, W. J., de Man, F. S. & Vonk-Noordegraaf, A., 2015, In : Pulmonary Circulation. 5, 3, p. 466-472

Research output: Contribution to journalArticleAcademicpeer-review

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

Le Hiress, M., Tu, L., Ricard, N., Phan, C., Thuillet, R., Fadel, E., Dorfmuller, P., Montani, D., de Man, F. S., Humbert, M., Huertas, A. & Guignabert, C., 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 8, p. 983-997

Research output: Contribution to journalArticleAcademicpeer-review

Quadriceps muscle fibre dysfunction in patients with pulmonary arterial hypertension

Manders, E., Ruiter, G., Bogaard, H. J., Stienen, G. J. M., Vonk Noordegraaf, A., de Man, F. S. & Ottenheijm, C. A. C., 2015, In : European Respiratory Journal. 45, 6, p. 1737-1740

Research output: Contribution to journalArticleAcademicpeer-review

23 Downloads (Pure)

Right ventricular diastolic dysfunction in pulmonary arterial hypertension

Rain, S., 2015

Research output: ThesisResearch VU University Amsterdam, graduation VU University AmsterdamAcademic

File

Risk-stratification in normotensive acute pulmonary embolism

Handoko, M. L. & de Man, F. S., 2015, In : Netherlands Heart Journal. 23, 1, p. 52-54

Research output: Contribution to journalArticleAcademicpeer-review

Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model

de Raaf, M. A., Kroeze, Y., Middelman, A., de Man, F. S., de Jong, H., Vonk-Noordegraaf, A., de Korte, C., Voelkel, N. F., Homberg, J. & Bogaard, H. J., 2015, In : American Journal of Physiology. Lung Cellular and Molecular Physiology. 309, 10, p. L1164-L1173

Research output: Contribution to journalArticleAcademicpeer-review