Frank Niessen

DR., (Principal Investigator)

20082019
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Research Output 2008 2019

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Article

Monocytes co-cultured with reconstructed keloid and normal skin models skew towards M2 macrophage phenotype

Limandjaja, G. C., Waaijman, T., Roffel, S., Niessen, F. B. & Gibbs, S., 1 Oct 2019, In : Archives of Dermatological Research. 311, 8, p. 615-627

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

PCR Characterization of Microbiota on Contracted and Non-Contracted Breast Capsules

Bachour, Y., Poort, L., Verweij, S. P., van Selms, G., Winters, H. A. H., Ritt, M. J. P. F., Niessen, F. B. & Budding, A. E., 15 Aug 2019, In : Aesthetic Plastic Surgery. 43, 4, p. 918-926 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Poly implant prothèse silicone breast explants: Chemical analysis of silicone gel and implant shell

Bachour, Y., Heinze, Z., van Selms, G., Ritt, M., Niessen, F. & Keizers, P., 1 Jan 2019, In : Plastic and Reconstructive Surgery - Global Open. 7, 1, e2093.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Toll-Like Receptors (TLRs) Expression in Contracted Capsules Compared to Uncontracted Capsules

Bachour, Y., Ritt, M. J. P. F., Heijmans, R., Niessen, F. B. & Verweij, S. P., 15 Aug 2019, In : Aesthetic Plastic Surgery. 43, 4, p. 910-917

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Characterization of In Vitro Reconstructed Human Normotrophic, Hypertrophic, and Keloid Scar Models

Limandjaja, G. C., van den Broek, L. J., Breetveld, M., Waaijman, T., Monstrey, S., de Boer, E. M., Scheper, R. J., Niessen, F. B. & Gibbs, S., Apr 2018, In : Tissue Engineering - Part C: Methods. 24, 4, p. 242-253 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Intralesional cryotherapy versus excision with corticosteroid injections or brachytherapy for keloid treatment: Randomised controlled trials

Bijlard, E., Niessen, F. B., Timman, R., Verduijn, G. M., Hovius, S. E. R. & Mureau, M. A. M., 1 Jun 2018, In : Journal of Plastic, Reconstructive and Aesthetic Surgery. 71, 6, p. 847-856 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Optimal High-Dose-Rate Brachytherapy Fractionation Scheme After Keloid Excision: A Retrospective Multicenter Comparison of Recurrence Rates and Complications

Bijlard, E., Verduijn, G. M., Harmeling, J. X., Dehnad, H., Niessen, F. B., Meijer, O. W. M. & Mureau, M. A. M., 1 Mar 2018, In : International Journal of Radiation Oncology Biology Physics. 100, 3, p. 679-686 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Poly Implant Prothèse silicone breast implants: implant dynamics and capsular contracture

Bachour, Y., Heinze, Z. C. M., Dormaar, T. S., van Selms, W. G., Ritt, M. J. P. F. & Niessen, F. B., 1 Oct 2018, In : European Journal of Plastic Surgery. 41, 5, p. 563-570 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reconstructed human keloid models show heterogeneity within keloid scars

Limandjaja, G. C., van den Broek, L. J., Waaijman, T., Breetveld, M., Monstrey, S., Scheper, R. J., Niessen, F. B. & Gibbs, S., Dec 2018, In : Archives of Dermatological Research. 310, 10, p. 815-826 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Histological Composition of Capsular Contracture Focussed on the Inner Layer of the Capsule: An Intra-Donor Baker-I Versus Baker-IV Comparison

de Bakker, E., van den Broek, LJ., Ritt, MJPF., Gibbs, S. & Niessen, FB., 1 Dec 2018, In : Aesthetic Plastic Surgery. 42, 6, p. 1485-1491 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2017

A biomechanical mathematical model for the collagen bundle distribution-dependent contraction and subsequent retraction of healing dermal wounds

Koppenol, D. C., Vermolen, F. J., Niessen, F. B., van Zuijlen, P. P. M. & Vuik, K., 1 Feb 2017, In : Biomechanics and Modeling in Mechanobiology. 16, 1, p. 345-361 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

A mathematical model for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding

Koppenol, D. C., Vermolen, F. J., Niessen, F. B., van Zuijlen, P. P. M. & Vuik, K., 1 Feb 2017, In : Biomechanics and Modeling in Mechanobiology. 16, 1, p. 15-32 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Breast-conserving therapy for breast cancer: Cosmetic results and options for delayed reconstruction

Negenborn, V. L., Volders, J. H., Krekel, N. M. A., Haloua, M. H., Bouman, M-B., Buncamper, M. E., Niessen, F. B., Winters, H. A. H., Terwee, C. B., Meijer, S. & van den Tol, M. P., Oct 2017, In : Journal of Plastic, Reconstructive and Aesthetic Surgery. 70, 10, p. 1336-1344 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Different properties of skin of different body sites: The root of keloid formation?

Butzelaar, L., Niessen, F. B., Talhout, W., Schooneman, D. P. M., Ulrich, M. M., Beelen, R. H. J. & Mink van der Molen, A. B., 25 Sep 2017, In : Wound Repair and Regeneration. 25, 5, p. 758-766 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Eenzijdige blindheid na een neuscorrectie met filler

Schelke, L. W., Fick, M., Van Rijn, L. J., Decates, T., Velthuis, P. J. & Niessen, F., 2017, In : Nederlands Tijdschrift voor Geneeskunde. 161, 49, D1246.

Research output: Contribution to journalArticleProfessional

Increased epidermal thickness and abnormal epidermal differentiation in keloid scars

Limandjaja, G. C., van den Broek, L. J., Waaijman, T., van Veen, H. A., Everts, V., Monstrey, S., Scheper, R. J., Niessen, F. B. & Gibbs, S., 1 Jan 2017, In : British Journal of Dermatology. 176, 1, p. 116-126 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Investigating histological aspects of scars in children

Westra, I., Verhaegen, P. D. H. M., Ibrahim Korkmaz, H., Braam, K. I., Kaspers, G. J. L., Niessen, H. W. M. & Niessen, F. B., 2 May 2017, In : Journal of Wound Care. 26, 5, p. 256-265 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

The development of the cleft aesthetic rating scale: A new rating scale for the assessment of nasolabial appearance in complete unilateral cleft lip and palate patients

Mosmuller, D. G. M., Mennes, L. M., Prahl, C., Kramer, G. J. C., Disse, M. A., Van Couwelaar, G. M., Niessen, F. B. & Don Griot, J. P. W., 1 Sep 2017, In : Cleft Palate-Craniofacial Journal. 54, 5, p. 555-561 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

A mathematical model for the simulation of the contraction of burns

Koppenol, D. C., Vermolen, F. J., Koppenol-Gonzalez, G. V., Niessen, F. B., van Zuijlen, P. P. M. & Vuik, K., 2016, In : Journal of Mathematical Biology. p. 1-31 31 p.

Research output: Contribution to journalArticleAcademicpeer-review

Currently known risk factors for hypertrophic skin scarring: A review

Butzelaar, L., Ulrich, M. M. W., van der Molen, A. B. M., Niessen, F. B. & Beelen, R. H. J., Feb 2016, In : Journal of Plastic, Reconstructive and Aesthetic Surgery. 69, 2, p. 163-169

Research output: Contribution to journalArticleAcademicpeer-review

Extensive Characterization and Comparison of Endothelial Cells Derived from Dermis and Adipose Tissue: Potential Use in Tissue Engineering

Monsuur, H. N., Weijers, E. M., Niessen, F. B., Gefen, A., Koolwijk, P., Gibbs, S. & van den Broek, L. J., 30 Nov 2016, In : PLoS ONE. 11, 11, e0167056.

Research output: Contribution to journalArticleAcademicpeer-review

Inhibited early immunologic response is associated with hypertrophic scarring

Butzelaar, L., Schooneman, D. P. M., Soykan, E. A., Talhout, W., Ulrich, M. M. W., van den Broek, L. J., Gibbs, S., Beelen, R. H. J., van der Molen, A. B. M. & Niessen, F. B., Oct 2016, In : Experimental Dermatology. 25, 10, p. 797-804

Research output: Contribution to journalArticleAcademicpeer-review

The Use of Autologous Fat Grafting for Treatment of Scar Tissue and Scar-Related Conditions: A Systematic Review

Negenborn, V. L., Groen, J-W., Smit, J. M., Niessen, F. B. & Mullender, M. G., Jan 2016, In : Plastic and reconstructive surgery. 137, 1, p. 31E-43E

Research output: Contribution to journalArticleAcademicpeer-review

Topical silicone sheet application in the treatment of hypertrophic scars and keloids

Westra, I. & Niessen, F. B., 1 Oct 2016, In : Journal of Clinical and Aesthetic Dermatology. 9, 10, p. 28-35 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2015

Comparison of two devices for the treatment of keloid scars with the use of intralesional cryotherapy: An experimental study

van Leeuwen, M. C. E., Bulstra, A. E. J., van der Veen, A. J., Bloem, W. B., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Cryobiology. 71, 1, p. 146-150

Research output: Contribution to journalArticleAcademicpeer-review

Going into surgery: Risk factors for hypertrophic scarring

Butzelaar, L., Soykan, E. A., Galindo Garre, F., Beelen, R. H. J., Ulrich, M. M. W., Niessen, F. B. & van der Molen, A. B. M., 2015, In : Wound Repair and Regeneration. 23, 4, p. 531-537

Research output: Contribution to journalArticleAcademicpeer-review

Implementing Real-Time Video Consultation in Plastic Surgery

Westra, I. & Niessen, F. B., 2015, In : Aesthetic Plastic Surgery. 39, 5, p. 783-790

Research output: Contribution to journalArticleAcademicpeer-review

In a clinimetric analysis, 3D stereophotogrammetry was found to be reliable and valid for measuring scar volume in clinical research

Stekelenburg, C. M., Jaspers, M. E. H., Niessen, F. B., Knol, D. L., van der Wal, M. B. A., de Vet, H. C. W. & van Zuijlen, P. P. M., 2015, In : Journal of Clinical Epidemiology. 68, 7, p. 782-787

Research output: Contribution to journalArticleAcademicpeer-review

Intralesional 5-Fluorouracil in Keloid Treatment: A Systematic Review

Bijlard, E., Steltenpool, S. & Niessen, F. B., 2015, In : Acta Derma-Venereologica. 95, 7, p. 778-782

Research output: Contribution to journalArticleAcademicpeer-review

Intralesional Cryotherapy for the Treatment of Keloid Scars: Evaluating Effectiveness

van Leeuwen, M. C. E., Bulstra, A. E., Ket, J. C. F., Ritt, M. J. P. F., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery.Global open. 3, 6, p. e437-e437

Research output: Contribution to journalArticleAcademicpeer-review

Intralesional Cryotherapy for Treatment of Keloid Scars: A Prospective Study

van Leeuwen, M. C. E., van der Wal, M. B. A., Bulstra, A. E. J., Galindo Garre, F., Molier, J., van Zuijlen, P. P. M., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery. 135, 2, p. 580-589

Research output: Contribution to journalArticleAcademicpeer-review

No Efficacy for Silicone Gel Sheeting in Prevention of Abnormal Scar Formation in Children with Cancer: A Randomized Controlled Trial

Braam, K. I., Kooijmans, E. C. M., van Dulmen-den Broeder, E., Veening, M. A., Schouten-van Meeteren, A. Y. N., Verhaegen, P. D. H. M., Kaspers, G. J. L., Niessen, F. B. & Heij, H. A., 2015, In : Plastic and reconstructive surgery. 135, 4, p. 1086-1094

Research output: Contribution to journalArticleAcademicpeer-review

Reply: High-Dose-Rate Brachytherapy for the Treatment of Recalcitrant Keloids: A Unique Effective Treatment Protocol

van Leeuwen, M. C. E., Stokmans, S. C., Bulstra, A. E. J., Meijer, O. W. M., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery. 135, 4, p. 792E-793E

Research output: Contribution to journalArticleAcademicpeer-review

Reply: Intralesional Cryotherapy for the Treatment of Keloid Scars: A Prospective Study

van Leeuwen, M. C. E., van der Wal, M. B. A., Bulstra, A. E. J., Galindo Garre, F., Molier, J., van Zuijlen, P. P. M., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery. 136, 3, p. 395E-397E

Research output: Contribution to journalArticleAcademicpeer-review

Suppressed inflammatory gene expression during human hypertrophic scar compared to normotrophic scar formation

van den Broek, L. J., van der Veer, W. M., de Jong, E. H., Gibbs, S. & Niessen, F. B., 2015, In : Experimental Dermatology. 24, 8, p. 623-629

Research output: Contribution to journalArticleAcademicpeer-review

Surgical Excision with Adjuvant Irradiation for Treatment of Keloid Scars: A Systematic Review

van Leeuwen, M. C. E., Stokmans, S. C., Bulstra, A. E., Meijer, O. W. M., Heymans, M. W., Ket, J. C. F., Ritt, M. J. P. F., van Leeuwen, P. A. M. & Niessen, F. B., 2015, In : Plastic and reconstructive surgery.Global open. 3, 7, e440.

Research output: Contribution to journalArticleAcademicpeer-review

The Asher-McDade Aesthetic Index in Comparison With Two Scoring Systems in Nonsyndromic Complete Unilateral Cleft Lip and Palate Patients

Mosmuller, D. G. M., Bijnen, C. L., Kramer, G. J. C., Disse, M. A., Prahl, C., Kuik, D. J., Niessen, F. B. & don Griot, J. P. W., 2015, In : Journal of Craniofacial Surgery. 26, 4, p. 1242-1245

Research output: Contribution to journalArticleAcademicpeer-review

The number of immune cells is lower in healthy oral mucosa compared to skin and does not increase after scarring

Glim, J. E., Beelen, R. H. J., Niessen, F. B., Everts, V. & Ulrich, M. M. W., 2015, In : Archives of Oral Biology. 60, 2, p. 272-281

Research output: Contribution to journalArticleAcademicpeer-review

Wondgenezing en tissue engineering

Gibbs, S., Blok, C. S., van den Broek, L. J., Weijers, E. M., Bergers, L. I. J. C., Limandjaja, G. C., Niessen, F. B., van Montfrans, C. & de Boer, E. M., 2015, In : Nederlands Tijdschrift voor Dermatologie en Venereologie. 25, 6, p. 275-278

Research output: Contribution to journalArticleProfessional

2014

A new argon gas-based device for the treatment of keloid scars with the use of intralesional cryotherapy

van Leeuwen, M. C. E., Bulstra, A. E. J., van Leeuwen, P. A. M. & Niessen, F. B., 2014, In : Journal of Plastic, Reconstructive and Aesthetic Surgery. 67, 12, p. 1703-1710

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of Two Scoring Systems in the Assessment of Nasolabial Appearance in Cleft Lip and Palate Patients

Mosmuller, D. G. M., Bijnen, C. L., don Griot, J. P. W., Kramer, G., Disse, M., Prahl, C., Kuik, D. J. & Niessen, F. B., 2014, In : Journal of Craniofacial Surgery. 25, 4, p. 1222-1225

Research output: Contribution to journalArticleAcademicpeer-review

Cosmetic Outcome Assessment following Breast-Conserving Therapy: A Comparison between BCCT.core Software and Panel Evaluation

Haloua, M. H., Krekel, N. M. A., Jacobs, G. J. A., Zonderhuis, B. M., Bouman, M. B., Buncamper, M. E., Niessen, F. B., Winters, H. A. H., Terwee, C. B., Meijer, S. & van den Tol, M. P., 2014, In : International journal of breast cancer. 2014, 716860.

Research output: Contribution to journalArticleAcademicpeer-review

Differential response of human adipose tissue-derived mesenchymal stem cells, dermal fibroblasts, and keratinocytes to burn wound exudates: potential role of skin-specific chemokine CCL27

van den Broek, L. J., Kroeze, K. L., Waaijman, T., Breetveld, M., Sampat-Sardjoepersad, S. C., Niessen, F. B., Middelkoop, E., Scheper, R. J. & Gibbs, S., Jan 2014, In : Tissue Engineering Part A. 20, 1-2, p. 197-209 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Excessieve littekens

Westra, I. & Niessen, F. B., 2014, In : Nederlands tijdschrift voor plastische chirurgie. 2014, 1, p. 26-28

Research output: Contribution to journalArticleProfessional

Extracellular matrix components of oral mucosa differ from skin and resemble that of foetal skin

Glim, J. E., Everts, V., Niessen, F. B., Ulrich, M. M. W. & Beelen, R. H. J., 2014, In : Archives of Oral Biology. 59, 10, p. 1048-1055

Research output: Contribution to journalArticleAcademicpeer-review

High-Dose-Rate Brachytherapy for the Treatment of Recalcitrant Keloids: A Unique, Effective Treatment Protocol

van Leeuwen, M. C. E., Stokmans, S. C., Bulstra, A. E. J., Meijer, O. W. M., van Leeuwen, P. A. M. & Niessen, F. B., 2014, In : Plastic and reconstructive surgery. 134, 3, p. 527-534

Research output: Contribution to journalArticleAcademicpeer-review

Human hypertrophic and keloid scar models: principles, limitations and future challenges from a tissue engineering perspective

van den Broek, L. J., Limandjaja, G. C., Niessen, F. B. & Gibbs, S., 2014, In : Experimental Dermatology. 23, 6, p. 382-386

Research output: Contribution to journalArticleAcademicpeer-review