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Research Output 1993 2019

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2005

Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis

Vos, C. M. P., Geurts, J. J. G., Montagne, L., van Haastert, E. S., Bö, L., van der Valk, P., Barkhof, F. & de Vries, H. E., 2005, In : Neurobiology of Disease. 20, 3, p. 953-960

Research output: Contribution to journalArticleAcademicpeer-review

Changes in brain electrical activity during extended continuous word recognition

Van Strien, J. W., Hagenbeek, R. E., Stam, C. J., Rombouts, S. A. R. B. & Barkhof, F., 1 Jul 2005, In : NeuroImage. 26, 3, p. 952-9 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Delayed rather than decreased BOLD response as a marker for early Alzheimer's disease

Rombouts, S. A. R. B., Goekoop, R., Stam, C. J., Barkhof, F. & Scheltens, P., 15 Jul 2005, In : NeuroImage. 26, 4, p. 1078-85 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Histopathologic correlates of radial stripes on MR images in lysosomal storage disorders

Van Der Voorn, J. P., Pouwels, P. J. W., Kamphorst, W., Powers, J. M., Lammens, M., Barkhof, F. & Van Der Knaap, M. S., 1 Dec 2005, In : American Journal of Neuroradiology. 26, 3, p. 442-446 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Retinoblastoma: MR imaging parameters in detection of tumor extent

de Graaf, P., Barkhof, F., Moll, AC., Imhof, SM., Knol, DL., van der Valk, P. & Castelijns, JA., 2005, In : Radiology. 235, p. 197-207

Research output: Contribution to journalArticleAcademicpeer-review

Stereotactic radiosurgery for brain AVMs: Role of interobserver variation in target definition on digital subtraction angiography

Buis, D. R., Lagerwaard, F. J., Barkhof, F., Dirven, C. M. F., Lycklama, G. J., Meijer, O. W. M., Van Den Berg, R., Langendijk, H. A., Slotman, B. J. & Vandertop, W. P., 1 May 2005, In : International Journal of Radiation Oncology Biology Physics. 62, 1, p. 246-252 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2004

Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease

Karas, G. B., Scheltens, P., Rombouts, S. A. R. B., Visser, P. J., van Schijndel, R. A., Fox, N. C. & Barkhof, F., 2004, In : NeuroImage. 23, 2, p. 708-716

Research output: Contribution to journalArticleAcademicpeer-review

Measuring progression of cerebral white matter lesions on MRI: Visual rating and volumetrics

Prins, N. D., van Straaten, E. C. W., van Dijk, E. J., Simoni, M., van Schijndel, R. A., Vrooman, H. A., Koudstaal, P. J., Scheltens, P., Breteler, M. M. B. & Barkhof, F., 2004, In : Neurology. 62, 9, p. 1533-1539

Research output: Contribution to journalArticleAcademicpeer-review

Monocyte activation and disease activity in multiple sclerosis. A longitudinal analysis of serum MRP8/14 levels

Floris, S., van der Goes, A., Killestein, J., Knol, D. L., Barkhof, F., Polman, C. H., Dijkstra, C. D., de Vries, H. E. & Meilof, J. F., Mar 2004, In : Journal of Neuroimmunology. 148, 1-2, p. 172-7 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nieuwe diagnostische criteria voor multiple sclerose in de praktijk

Van Oosten, B. W., Barkhof, F. & Polman, C. H., 17 Jul 2004, In : Nederlands Tijdschrift voor Geneeskunde. 148, 29, p. 1417-1422 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2003

A comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry

Karas, G. B., Burton, E. J., Rombouts, S. A. R. B., Van Schijndel, R. A., O'Brien, J. T., Scheltens, P., McKeith, I. G., Williams, D., Ballard, C. & Barkhof, F., 1 Apr 2003, In : NeuroImage. 18, 4, p. 895-907 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

A new leukodystrophy with brainstem and spinal cord involvement and high lactate

Van der Knaap, M. S., Van Der Voorn, P., Barkhof, F., Van Coster, R., Krägeloh-Mann, I., Feigenbaum, A., Blaser, S., Vles, J. S. H., Rieckmann, P. & Pouwels, P. J. W., 1 Feb 2003, In : Annals of Neurology. 53, 2, p. 252-258 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Diffusiegewogen MRI bij neonatale Bacillus cereus meningo-encefalitis

Vermeulen, R. J., Van Elburg, R. M., Van Der Zwet, W. C., Van Furth, A. M., Verbeke, J. I. M. L., Barkhof, F. & Van Der Knaap, M. S., 1 Apr 2003, In : Tijdschrift voor Kindergeneeskunde. 71, 2, p. 45-49 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identifying confounds to increase specificity during a "no task condition". Evidence for hippocampal connectivity using fMRI

Rombouts, S. A. R. B., Stam, C. J., Kuijer, J. P. A., Scheltens, P. & Barkhof, F., Oct 2003, In : NeuroImage. 20, 2, p. 1236-45 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multislice T1 Relaxation Time Measurements in the Brain Using IR-EPI: Reproducibility, Normal Values, and Histogram Analysis in Patients with Multiple Sclerosis

Van Walderveen, M. A. A., Van Schijndel, R. A., Pouwels, P. J. W., Polman, C. H. & Barkhof, F., 1 Dec 2003, In : Journal of Magnetic Resonance Imaging. 18, 6, p. 656-664 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Oral interferon beta-1a in relapsing-remitting multiple sclerosis: A double-blind randomized study

Polman, C., Barkhof, F., Kappos, L., Pozzilli, C., Sandbrink, R., Dahlke, F., Jakobs, P., Lorenz, A., Hern, J., Coleman, R., Soelberg Srensen, P., Hartung, H. P., Fredrikson, S., Selmaj, K., Pelletier, J., D'Hooghe, M. B., Comi, G., Hohfeld, R., Gold, R., Panelius, M. & 17 othersRuutiainen, J., Clanet, M., de Vos, M., Jonker, M., van Ijken, T., Jansen, E., van Schijndel, R., Karas, G., Wagner, K., Ghazi, M., Kurth, D., Sauerbrey, K., Tries, E., McFarland, H. F., Miller, D. H., Montalban, X. & Petkau, J., 2003, In : Multiple Sclerosis. 9, 4, p. 342-348

Research output: Contribution to journalArticleAcademicpeer-review

Remyelinated lesions in multiple sclerosis: Magnetic resonance image appearance

Barkhof, F., Brück, W., de Groot, C. J. A., Bergers, E., Hulshof, S., Geurts, J., Polman, C. H. & van der Valk, P., 2003, In : Archives of Neurology. 60, 8, p. 1073-1081

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Thallium-201 single-photon emission computed tomography as an early predictor of outcome in recurrent glioma

Vos, M. J., Hoekstra, O. S., Barkhof, F., Berkhof, J., Heimans, J. J., van Groeningen, C. J., Vandertop, W. P., Slotman, B. J. & Postma, T. J., 1 Oct 2003, In : Journal of Clinical Oncology. 21, 19, p. 3559-65 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2002

Brain atrophy in multiple sclerosis: Impact of lesions and of damage of whole brain tissue

Kalkers, N. F., Vrenken, H., Uitdehaag, B. M. J., Polman, C. H. & Barkhof, F., 1 Oct 2002, In : Multiple Sclerosis. 8, 5, p. 410-414 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Image registration and subtraction to detect active T2 lesions in MS: An interobserver study

Tan, I. L., Van Schijndel, R. A., Fazekas, F., Filippi, M., Freitag, P., Miller, D. H., Yousry, T. A., Pouwels, P. J. W., Adèr, H. J. & Barkhof, F., 1 Jan 2002, In : Journal of Neurology. 249, 6, p. 767-773 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients: Initial experience

Tan, I. L., Pouwels, P. J. W., van Schijndel, R. A., Adèr, H. J., Manoliu, R. A. & Barkhof, F., 1 Mar 2002, In : European Radiology. 12, 3, p. 559-567 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Magnetic resonance image registration in multiple sclerosis: Comparison with repositioning error and observer-based variability

Leng Tan, I., Van Schijndel, R. A., Van Walderveen, M. A. A., Quist, M., Bos, R., Pouwels, P. J. W., Desmedt, P., Adr, H. J. & Barkhof, F., 13 May 2002, In : Journal of Magnetic Resonance Imaging. 15, 5, p. 505-510 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Serial isotropic three-dimensional fast FLAIR imaging: Using image registration and subtraction to reveal active multiple sclerosis lesions

Tan, I. L., Van Schijndel, R. A., Pouwels, P. J. W., Adèr, H. J. & Barkhof, F., 1 Jan 2002, In : American Journal of Roentgenology. 179, 3, p. 777-782 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: A pilot study

Kalkers, N. F., Barkhof, F., Bergers, E., van Schijndel, R. & Polman, C. H., 2002, In : Multiple Sclerosis. 8, 6, p. 532-533

Research output: Contribution to journalArticleAcademicpeer-review

2001

Improved interobserver agreement for visual detection of active T2 lesions on serial MR scans in multiple sclerosis using image registration

Tan, I. L., Van Schijndel, R. A., Fazekas, F., Filippi, M., Freitag, P., Miller, D. H., Yousry, T. A., Pouwels, P. J. W., Adèr, H. J., Quist, M. J. & Barkhof, F., 1 Jan 2001, In : Journal of Neural Transmission. 108, 8-9, p. 789-794 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2000

MR venography of multiple sclerosis

Tan, I. L., Van Schijndel, R. A., Pouwels, P. J. W., Van Walderveen, M. A. A., Reichenbach, J. R., Manoliu, R. A. & Barkhof, F., 30 Jun 2000, In : American Journal of Neuroradiology. 21, 6, p. 1039-1042 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

1999

Decreased interleukin-10 and increased interleukin- 12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis

Van Boxel-Dezaire, A. H. H., Hoff, S. C. J., Van Oosten, B. W., Verweij, C. L., Dräger, A. M., Adèr, H. J., Van Houwelingen, J. C., Barkhof, F., Polman, C. H. & Nagelkerken, L., 15 Jun 1999, In : Annals of Neurology. 45, 6, p. 695-703 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of hypointense lesions on T1-weighted spin-echo magnetic resonance images in multiple sclerosis: Relation to inflammatory activity

Van Walderveen, M. A. A., Truyen, L., Van Oosten, B. W., Castelijns, J. A., Lycklama À Nijeholt, G. J., Van Waesberghe, J. H. T. M., Polman, C. & Barkhof, F., 1 Jan 1999, In : Archives of Neurology. 56, 3, p. 345-351 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy

Van Walderveen, M. A. A., Barkhof, F., Pouwels, P. J. W., Van Schijndel, R. A., Polman, C. H. & Castelijns, J. A., 17 Jul 1999, In : Annals of Neurology. 46, 1, p. 79-87 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1998

Increased production of tumor necrosis factor α, and not of interferon γ, preceding disease activity in patients with multiple sclerosis

Van Oosten, B. W., Barkhof, F., Scholten, P. E. T., Von Blomberg, B. M. E., Adèr, H. J. & Polman, C. H., 1 Jun 1998, In : Archives of Neurology. 55, 6, p. 793-798 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

1997

Interleukin-2 therapy does not exacerbate multiple sclerosis

Van Oosten, B. W., Uitdehaag, B. M. J., Barkhof, F., Hartung, H. P., Wagstaff, J. & Polman, C. H., 1 Jan 1997, In : Neurology. 49, 2, p. 633-634 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: Results of a randomized, double-blind, placebo-controlled, MR- monitored phase II trial

Van Oosten, B. W., Lai, M., Hodgkinson, S., Barkhof, F., Miller, D. H., Moseley, I. F., Thompson, A. J., Rudge, P., McDougall, A., McLeod, J. G., Adèr, H. J. & Polman, C. H., 1 Jan 1997, In : Neurology. 49, 2, p. 351-357 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1996

Accumulation of hypointense lesions ('black holes') on T1 spin-echo MRI correlates with disease progression in multiple sclerosis

Truyen, L., Van Waesberghe, J. H. T. M., Van Walderveen, M. A. A., Van Oosten, B. W., Polman, C. H., Hommes, O. R., Adèr, H. J. A. & Barkhof, F., 1 Jan 1996, In : Neurology. 47, 6, p. 1469-1476 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A phase II trial of anti-CD4 antibodies in the treatment of multiple sclerosis

Van Oosten, B. W., Lai, M., Barkhof, F., Miller, D. H., Moseley, I. F., Thompson, A. J., Hodgkinson, S. & Polman, C. H., 1 Jan 1996, In : Multiple Sclerosis. 1, 6, p. 339-342 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2

Van Oosten, B. W., Barkhof, F., Truyen, L., Boringa, J. B., Bertelsmann, F. W., Von Blomberg, B. M. E., Woody, J. N., Hartung, H. P. & Polman, C. H., 1 Jan 1996, In : Neurology. 47, 6, p. 1531-1534 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

1995

Multiple Sclerosis Therapy: A Practical Guide

van Oosten, B. W., Truyen, L., Barkhof, F. & Polman, C. H., 1 Jan 1995, In : Drugs. 49, 2, p. 200-212 13 p.

Research output: Contribution to journalArticleAcademicpeer-review