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Research Output 1993 2019

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2015

Resting state functional connectivity differences between behavioral variant frontotemporal dementia and Alzheimer's disease

Hafkemeijer, A., Möller, C., Dopper, E. G. P., Jiskoot, L. C., Schouten, T. M., van Swieten, J. C., van der Flier, W. M., Vrenken, H., Pijnenburg, Y. A. L., Barkhof, F., Scheltens, P., van der Grond, J. & Rombouts, S. A. R. B., 2015, In : Frontiers in Human Neuroscience. 9, 474.

Research output: Contribution to journalArticleAcademicpeer-review

Shape abnormalities of the caudate nucleus correlate with poorer gait and balance: Results from a subset of the ladis study

LADIS Study Group, 1 Jan 2015, In : American Journal of Geriatric Psychiatry. 23, 1, p. 59-71.e1

Research output: Contribution to journalArticleAcademicpeer-review

Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge

Bron, E. E., Smits, M., van der Flier, W. M., Vrenken, H., Barkhof, F., Scheltens, P., Papma, J. M., Steketee, R. M. E., Orellana, C. M., Meijboom, R., Pinto, M., Meireles, J. R., Garrett, C., Bastos-Leite, A. J., Abdulkadir, A., Ronneberger, O., Amoroso, N., Bellotti, R., Cardenas-Pena, D., Alvarez-Meza, A. M. & 30 othersDolph, C. V., Iftekharuddin, K. M., Eskildsen, S. F., Coupe, P., Fonov, V. S., Franke, K., Gaser, C., Ledig, C., Guerrero, R., Tong, T., Gray, K. R., Moradi, E., Tohka, J., Routier, A., Durrleman, S., Sarica, A., Di Fatta, G., Sensi, F., Chincarini, A., Smith, G. M., Stoyanov, Z. V., Sorensen, L., Nielsen, M., Tangaro, S., Inglese, P., Wachinger, C., Reuter, M., van Swieten, J. C., Niessen, W. J. & Klein, S., 2015, In : NeuroImage. 111, p. 562-579

Research output: Contribution to journalArticleAcademicpeer-review

Structural MRI substrates of cognitive impairment in neuromyelitis optica

Liu, Y., Fu, Y., Schoonheim, M. M., Zhang, N., Fan, M. L., Su, L., Shen, Y., Yan, Y. P., Yang, L., Wang, Q. H., Zhang, N. N. N., Yu, C. S., Barkhof, F. & Shi, F. D., 2015, In : Neurology. 85, 17, p. 1491-1499

Research output: Contribution to journalArticleAcademicpeer-review

Survival prediction model of children with diffuse intrinsic pontine glioma based on clinical and radiological criteria

Jansen, M. H. A., van Zanten, S. E. V., Sanchez Aliaga, E., Heymans, M. W., Warmuth-Metz, M., Hargrave, D., van der Hoeven, E. J., Gidding, C. E., de Bont, ES., Eshghi, O. S., Reddingius, R., Peeters, C. M., Schouten-van Meeteren, A. Y. N., Gooskens, R. H. J., Granzen, B., Paardekooper, G. M., Janssens, G. O., Noske, D. P., Barkhof, F., Kramm, C. M. & 3 othersVandertop, W. P., Kaspers, G. J. & van Vuurden, D. G., 2015, In : Neuro-Oncology. 17, 1, p. 160-166

Research output: Contribution to journalArticleAcademicpeer-review

Thalamus structure and function determine severity of cognitive impairment in multiple sclerosis

Schoonheim, M. M., Hulst, H. E., Brandt, R. B., Strik, M., Wink, A. M., Uitdehaag, B. M. J., Barkhof, F. & Geurts, J. J. G., 24 Feb 2015, In : Neurology. 84, 8, p. 776-83 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features

Ossenkoppele, R., Pijnenburg, Y. A. L., Perry, D. C., Cohn-Sheehy, B. I., Scheltens, N. M. E., Vogel, J. W., Kramer, J. H., van der Vlies, A. E., La Joie, R., Rosen, H. J., van der Flier, W. M., Grinberg, L. T., Rozemuller, A. J. M., Huang, E. J., van Berckel, B. N. M., Miller, B. L., Barkhof, F., Jagust, W. J., Scheltens, P., Seeley, W. W. & 1 othersRabinovici, G. D., 2015, In : Brain. 138, p. 2732-2749

Research output: Contribution to journalArticleAcademicpeer-review

The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

Frisoni, G. B., Jack, C. R., Bocchetta, M., Bauer, C., Frederiksen, K. S., Liu, Y. W., Preboske, G., Swihart, T., Blair, M., Cavedo, E., Grothe, M. J., Lanfredi, M., Martinez, O., Nishikawa, M., Portegies, M., Stoub, T., Ward, C., Apostolova, L. G., Ganzola, R., Wolf, D. & 34 othersBarkhof, F., Bartzokis, G., deCarli, C., Csernansky, J. G., DeToledo-Morrell, L., Geerlings, M. I., Kaye, J., Killiany, R. J., Lehericy, S., Matsuda, H., O'Brien, J., Silbert, L. C., Scheltens, P., Soininen, H., Teipel, S., Waldemar, G., Fellgiebel, A., Barnes, J., Firbank, M., Gerritsen, L., Henneman, W., Malykhin, N., Pruessner, J. C., Wang, L., Watson, C., Wolf, H., deLeon, M., Pantel, J., Ferrari, C., Bosco, P., Pasqualetti, P., Duchesne, S., Duvernoy, H. & Boccardi, M., 2015, In : Alzheimers & Dementia. 11, 2, p. 111-125

Research output: Contribution to journalArticleAcademicpeer-review

The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease

Louwersheimer, E., Ramirez, A., Cruchaga, C., Becker, T., Kornhuber, J., Peters, O., Heilmann, S., Wiltfang, J., Jessen, F., Visser, P. J., Scheltens, P., Pijnenburg, Y. A. L., Teunissen, C. E., Barkhof, F., van Swieten, J. C., Holstege, H. & van der Flier, W. M., 2015, In : Neurobiology of Aging. 36, 3, p. 1605-1620

Research output: Contribution to journalArticleAcademicpeer-review

Transient gadolinium leakage in natalizumab-treated multiple sclerosis

Haller, S., Barkhof, F., Wattjes, M. P. & Lalive, P. H., 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 4, p. 475-476

Research output: Contribution to journalArticleAcademicpeer-review

Using visual rating to diagnose dementia: a critical evaluation of MRI atrophy scales

Harper, L., Barkhof, F., Fox, N. & Schott, J. M., 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 11, p. 1225-1233

Research output: Contribution to journalArticleAcademicpeer-review

Volumetric MRI data correlate to disease severity in metachromatic leukodystrophy

Tillema, J. M., Derks, M. G. M., Pouwels, P. J. W., de Graaf, P., van Rappard, D. F., Barkhof, F., Steenweg, M. E., van der Knaap, M. S. & Wolf, N. I., 2015, In : Annals of Clinical and Translational Neurology. 2, 9, p. 932-940

Research output: Contribution to journalArticleAcademicpeer-review

What drives MRI-measured cortical atrophy in multiple sclerosis?

Popescu, V., Klaver, R., Voorn, P., van der Graaf, Y., Knol, D. L., Twisk, J. W. R., Versteeg, A., Schenk, G. J., van der Valk, P., Barkhof, F., de Vries, H. E., Vrenken, H. & Geurts, J. J. G., 1 Jan 2015, In : Multiple Sclerosis. 21, 10, p. 1280-1290 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

White Matter Hyperintensities Relate to Clinical Progression in Subjective Cognitive Decline

Benedictus, M. R., van Harten, A. C., Leeuwis, A. E., Koene, T., Scheltens, P., Barkhof, F., Prins, N. D. & van der Flier, W. M., 2015, In : Stroke. 46, 9, p. 2661-2664

Research output: Contribution to journalArticleAcademicpeer-review

2014

Accurate GM atrophy quantification in MS using lesion-filling with co-registered 2D lesion masks.

Popescu, V., Ran, N. C. G., Barkhof, F., Chard, D. T., Wheeler-Kingshott, C. A. M. & Vrenken, H., 2014, In : NeuroImage: Clinical. 4, p. 366-373

Research output: Contribution to journalArticleAcademicpeer-review

Amyloid and its association with default network integrity in Alzheimer's disease

Adriaanse, S. M., Sanz-Arigita, E. J., Binnewijzend, M. A. A., Ossenkoppele, R., Tolboom, N., van Assema, D. M. E., Wink, A. M., Boellaard, R., Yaqub, M. M., Windhorst, A. D., van der Flier, W. M., Scheltens, P., Lammertsma, A. A., Rombouts, S. A. R. B., Barkhof, F. & van Berckel, B. N. M., 2014, In : Human Brain Mapping. 35, 3, p. 779-791

Research output: Contribution to journalArticleAcademicpeer-review

An algorithmic approach to structural imaging in dementia

Harper, L., Barkhof, F., Scheltens, P., Schott, J. M. & Fox, N. C., 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 6, p. 692-698

Research output: Contribution to journalArticleAcademicpeer-review

Brain volume and white matter hyperintensities as determinants of cerebral blood flow in Alzheimer's disease.

Benedictus, M. R., Binnewijzend, M. A. A., Kuijer, J. P. A., Steenwijk, M. D., Versteeg, A., Vrenken, H., Scheltens, P., Barkhof, F., van der Flier, W. M. & Prins, N. D., 2014, In : Neurobiology of Aging. 35, 12, p. 2665-2670

Research output: Contribution to journalArticleAcademicpeer-review

CD49d antisense drug ATL1102 reduces disease activity in patients with relapsing-remitting MS

Limmroth, V., Barkhof, F., Desem, N., Diamond, M. P. & Tachas, G., 2014, In : Neurology. 83, 20, p. 1780-1788

Research output: Contribution to journalArticleAcademicpeer-review

Cerebrospinal fluid levels of Alzheimer's disease biomarkers in middle-aged patients with type 1 diabetes

Ouwens, D. M., van Duinkerken, E., Schoonenboom, S. N. M., de Wiza, D. H., Klein, M., van Golen, L. W., Pouwels, P. J. W., Barkhof, F., Moll, A. C., Snoek, F. J., Teunissen, C. E., Scheltens, P. & Diamant, M., 2014, In : Diabetologia. 57, 10, p. 2208-2214

Research output: Contribution to journalArticleAcademicpeer-review

Changes in MEG resting-state networks are related to cognitive decline in type 1 diabetes mellitus patients

Demuru, M., van Duinkerken, E., Fraschini, M., Marrosu, F., Snoek, F. J., Barkhof, F., Klein, M., Diamant, M. & Hillebrand, A., 2014, In : NeuroImage: Clinical. 5, p. 69-76

Research output: Contribution to journalArticleAcademicpeer-review

Daclizumab in multiple sclerosis: a high-yield extension study

Barkhof, F. & Ciccarelli, O., 2014, In : Lancet Neurology. 13, 5, p. 443-444

Research output: Contribution to journalArticleAcademicpeer-review

Defining the clinical course of multiple sclerosis The 2013 revisions

Lublin, F. D., Reingold, S. C., Cohen, J. A., Cutter, G. R., Sorensen, P. S., Thompson, A. J., Wolinsky, J. S., Balcer, L. J., Banwell, B., Barkhof, F., Bebo, B., Calabresi, P. A., Clanet, M., Comi, G., Fox, R. J., Freedman, M. S., Goodman, A. D., Inglese, M., Kappos, L., Kieseier, B. C. & 12 othersLincoln, J. A., Lubetzki, C., Miller, A. E., Montalban, X., O'Connor, P. W., Petkau, J., Pozzilli, C., Rudick, R. A., Sormani, M. P., Stuve, O., Waubant, E. & Polman, C. H., 2014, In : Neurology. 83, 3, p. 278-286

Research output: Contribution to journalArticleAcademicpeer-review

Determinants of iron accumulation in deep grey matter of multiple sclerosis patients

Ropele, S., Kilsdonk, I. D., Wattjes, M. P., Langkammer, C., de Graaf, W. L., Frederiksen, J. L., Larsson, H. B., Yiannakas, M., Wheeler-Kingshott, C. A. M., Enzinger, C., Khalil, M., Rocca, M. A., Sprenger, T., Amann, M., Kappos, L., Filippi, M., Rovira, A., Ciccarelli, O., Barkhof, F. & Fazekas, F., 2014, In : Multiple Sclerosis. 20, 13, p. 1692-1698

Research output: Contribution to journalArticleAcademicpeer-review

Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?

Wattjes, M. P., Vennegoor, A., Mostert, J., van Oosten, B. W., Barkhof, F. & Killestein, J., 2014, In : Journal of Neurology. 261, 6, p. 1139-1143

Research output: Contribution to journalArticleAcademicpeer-review

Diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy using MRI

Wattjes, M. P. & Barkhof, F., 2014, In : Current Opinion in Neurology. 27, 3, p. 260-270

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic value of brain chronic black holes on T1-weighted MR images in clinically isolated syndromes

Mitjana, R., Tintore, M., Rocca, M. A., Auger, C., Barkhof, F., Filippi, M., Polman, C., Fazekas, F., Huerga, E., Montalban, X. & Rovira, A., 2014, In : Multiple Sclerosis. 20, 11, p. 1471-1477

Research output: Contribution to journalArticleAcademicpeer-review

Differential impact of subclinical carotid artery disease on cerebral structure and functioning in type 1 diabetes patients with versus those without proliferative retinopathy

van Duinkerken, E., IJzerman, R. G., van der Zijl, N. J., Barkhof, F., Pouwels, P. J. W., Schoonheim, M. M., Moll, A. C., Boerop, J., Wessels, A. M., Klein, M., Snoek, F. J. & Diamant, M., 2014, In : Cardiovascular Diabetology. 13, 58.

Research output: Contribution to journalArticleAcademicpeer-review

Distinctive structural and functional MRI footprint for cognitive dysfunction in pediatric MS?

Tedeschi, G., Gallo, A. & Barkhof, F., 2014, In : Neurology. 82, 15, p. 1296-1297

Research output: Contribution to journalArticleAcademicpeer-review

Distinct perfusion patterns in Alzheimer's disease, frontotemporal dementia and dementia with Lewy bodies

Binnewijzend, M. A. A., Kuijer, J. P. A., van der Flier, W. M., Benedictus, M. R., Moller, C. M., Pijnenburg, Y. A. L., Lemstra, A. W., Prins, N. D., Wattjes, M. P., van Berckel, B. N. M., Scheltens, P. & Barkhof, F., 2014, In : European Radiology. 24, 9, p. 2326-2333

Research output: Contribution to journalArticleAcademicpeer-review

Effect of prior treatment status and reasons for discontinuation on the efficacy and safety of fingolimod vs. interferon β-1a intramuscular: Subgroup analyses of the Trial Assessing Injectable Interferon vs. Fingolimod Oral in Relapsing–Remitting Multiple Sclerosis (TRANSFORMS)

Khatri, B. O., Pelletier, J., Kappos, L., Hartung, H. P., Comi, G., Barkhof, F., von Rosenstiel, P., Meng, X., Grinspan, A., Hashmonay, R. & Cohen, J. A., 2014, In : Multiple Sclerosis and Related Disorders. 3, 3, p. 355-363

Research output: Contribution to journalArticleAcademicpeer-review

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Effects of Insulin Detemir and NPH Insulin on Body Weight and Appetite-Regulating Brain Regions in Human Type 1 Diabetes: A Randomized Controlled Trial

van Golen, L. W., Veltman, D. J., IJzerman, R. G., Deijen, J. B., Heijboer, A. C., Barkhof, F., Drent, M. L. & Diamant, M., 2014, In : PLoS ONE. 9, 4, p. e94483 e94483.

Research output: Contribution to journalArticleAcademicpeer-review

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Efficacy of subcutaneous interferon beta-1a on MRI outcomes in a randomised controlled trial of patients with clinically isolated syndromes

De Stefano, N., Comi, G., Kappos, L., Freedman, M. S., Polman, C. H., Uitdehaag, B. M. J., Hennessy, B., Casset-Semanaz, F., Lehr, L., Stubinski, B., Jack, D. L. & Barkhof, F., 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 6, p. 647-653

Research output: Contribution to journalArticleAcademicpeer-review

Functional connectivity and cognitive decline over 3 years in Parkinson disease

Olde Dubbelink, K. T. E., Schoonheim, M. M., Deijen, J. B., Twisk, J. W. R., Barkhof, F. & Berendse, H. W., 2014, In : Neurology. 83, 22, p. 2046-2053

Research output: Contribution to journalArticleAcademicpeer-review

Functional Correlates of Cognitive Dysfunction in Multiple Sclerosis: A Multicenter fMRI Study

Rocca, M. A., Valsasina, P., Hulst, H. E., Abdel-Aziz, K., Enzinger, C., Gallo, A., Pareto, D., Riccitelli, G., Muhlert, N., Ciccarelli, O., Barkhof, F., Fazekas, F., Tedeschi, G., Arevalo, M. J. & Filippi, M., 2014, In : Human Brain Mapping. 35, 12, p. 5799-5814

Research output: Contribution to journalArticleAcademicpeer-review

GLP-1 Receptor Activation Modulates Appetite- and Reward-Related Brain Areas in Humans

van Bloemendaal, L., IJzerman, R. G., ten Kulve, J. S., Barkhof, F., Konrad, R. J., Drent, M. L., Veltman, D. J. & Diamant, M., 2014, In : Diabetes. 63, 12, p. 4186-4196

Research output: Contribution to journalArticleAcademicpeer-review

Head Motion Parameters in fMRI Differ Between Patients with Mild Cognitive Impairment and Alzheimer Disease Versus Elderly Control Subjects

Haller, S., Monsch, A. U., Richiardi, J., Barkhof, F., Kressig, R. W. & Radue, E. W., 2014, In : Brain Topography. 27, 6, p. 801-807

Research output: Contribution to journalArticleAcademicpeer-review

Hippocampal volume change measurement: Quantitative assessment of the reproducibility of expert manual outlining and the automated methods FreeSurfer and FIRST

Mulder, E. R., de Jong, R. A., Knol, D. L., van Schijndel, R. A., Cover, K. S., Visser, P. J., Barkhof, F. & Vrenken, H., 2014, In : NeuroImage. 92, p. 169-181

Research output: Contribution to journalArticleAcademicpeer-review

Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla

Kilsdonk, I. D., Wattjes, M. P., Lopez-Soriano, A., Kuijer, J. P. A., de Jong, M. C., de Graaf, W. L., Conijn, M. M. A., Polman, C. H., Luijten, P. R., Geurts, J. J. G., Geerlings, M. I. & Barkhof, F., 2014, In : European Radiology. 24, 4, p. 841-849

Research output: Contribution to journalArticleAcademicpeer-review

Increased Number of Microinfarcts in Alzheimer Disease at 7-T MR Imaging

van Rooden, S., Goos, J. D. C., van Opstal, A. M., Versluis, M. J., Webb, A. G., Blauw, G. J., van der Flier, W. M., Scheltens, P., Barkhof, F., van Buchem, M. A. & van der Grond, J., 2014, In : Radiology. 270, 1, p. 205-211

Research output: Contribution to journalArticleAcademicpeer-review

Indicators for cognitive performance and subjective cognitive complaints in multiple sclerosis: a role for advanced MRI?

Hulst, H. E., Gehring, K., Uitdehaag, B. M. J., Visser, L. H., Polman, C. H., Barkhof, F., Sitskoorn, M. M. & Geurts, J. J. G., 2014, In : Multiple Sclerosis. 20, 8, p. 1131-1134

Research output: Contribution to journalArticleAcademicpeer-review