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2014

Quantitative regional validation of the visual rating scale for posterior cortical atrophy

Möller, C., van der Flier, W. M., Versteeg, A., Benedictus, M. R., Wattjes, M. P., Koedam, E. L. G. M., Scheltens, P., Barkhof, F. & Vrenken, H., 2014, In : European Radiology. 24, 2, p. 397-404

Research output: Contribution to journalArticleAcademicpeer-review

Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033

Tran, J. Q., Rana, J., Barkhof, F., Melamed, I., Gevorkyan, H., Wattjes, M. P., Jong, R., Brosofsky, K., Ray, S., Xu, L., Zhao, J., Parr, E. & Cadavid, D., 2014, In : Neurology neuroimmunology & neuroinflammation. 1, 2, e18.

Research output: Contribution to journalArticleAcademicpeer-review

Regional atrophy is associated with impairment in distinct cognitive domains in Alzheimer's disease

Smits, L. L., Tijms, B. M., Benedictus, M. R., Koedam, E. L. G. E., Koene, T., Reuling, I. E. W., Barkhof, F., Scheltens, P., Pijnenburg, Y. A. L., Wattjes, M. P. & van der Flier, W. M., 2014, In : Alzheimers & Dementia. 10, 5 Suppl, p. S299-S305

Research output: Contribution to journalArticleAcademicpeer-review

Resting-State Functional MR Imaging: A New Window to the Brain

Barkhof, F., Haller, S. & Rombouts, S. A. R. B., 2014, In : Radiology. 272, 1, p. 28-48

Research output: Contribution to journalArticleAcademicpeer-review

Single-subject gray matter graph properties and their relationship with cognitive impairment in early- and late-onset Alzheimer's disease

Tijms, B. M., Yeung, H. M., Sikkes, S. A. M., Moller, C., Smits, L. L., Stam, C. J., Scheltens, P., van der Flier, W. M. & Barkhof, F., 2014, In : Brain Connectivity. 4, 5, p. 337-346

Research output: Contribution to journalArticleAcademicpeer-review

Spinal cord MRI should always be performed in clinically isolated syndrome patients: Yes

Barkhof, F., 2014, In : Multiple Sclerosis. 20, 13, p. 1688-1689

Research output: Contribution to journalArticleAcademicpeer-review

Structural degree predicts functional network connectivity: A multimodal resting-state fMRI and MEG study

Tewarie, P., Hillebrand, A., van Dellen, E., Schoonheim, M. M., Barkhof, F., Polman, C. H., Beaulieu, C., Gong, G., van Dijk, B. W. & Stam, C. J., 2014, In : NeuroImage. 97, p. 296-307

Research output: Contribution to journalArticleAcademicpeer-review

The Dutch Parelsnoer Institute - Neurodegenerative diseases; methods, design and baseline results

Aalten, P., Ramakers, I. H. G. B., Biessels, G. J., de Deyn, P. P., Koek, H. L., Olde Rikkert, M. G. M., Oleksik, A. M., Richard, E., Smits, L. L., van Swieten, J. C., Teune, L. K., van der Lugt, A., Barkhof, F., Teunissen, C. E., Rozendaal, N., Verhey, F. R. J. & van der Flier, W. M., 2014, In : BMC Neurology. 14, 254.

Research output: Contribution to journalArticleAcademicpeer-review

The SIENA/FSL whole brain atrophy algorithm is no more reproducible at 3 T than 1.5 T for Alzheimer's disease

Cover, K. S., van Schijndel, R. A., Popescu, V., van Dijk, B. W., Redolfi, A., Knol, D. L., Frisoni, G. B., Barkhof, F. & Vrenken, H., 2014, In : Psychiatry Research: Neuroimaging. 224, 1, p. 14-21

Research output: Contribution to journalArticleAcademicpeer-review

Validation of the Automated Method VIENA: An Accurate, Precise, and Robust Measure of Ventricular Enlargement

Vrenken, H., Vos, E. K., van der Flier, W. M., Sluimer, I. C., Cover, K. S., Knol, D. L. & Barkhof, F., 2014, In : Human Brain Mapping. 35, 4, p. 1101-1110

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin D as an Early Predictor of Multiple Sclerosis Activity and Progression

Ascherio, A., Munger, K. L., White, R., Kochert, K., Simon, K. C., Polman, C. H., Freedman, M. S., Hartung, H. P., Miller, D. H., Montalban, X., Edan, G., Barkhof, F., Pleimes, D., Radu, E. W., Sandbrink, R., Kappos, L. & Pohl, C., 2014, In : JAMA Neurology. 71, 3, p. 306-314

Research output: Contribution to journalArticleAcademicpeer-review

What Explains Gray Matter Atrophy in Long-standing Multiple Sclerosis?

Steenwijk, M. D., Daams, M., Pouwels, P. J. W., Balk, L. J., Tewarie, P. K., Killestein, J., Uitdehaag, B. M. J., Geurts, J. J. G., Barkhof, F. & Vrenken, H., 2014, In : Radiology. 272, 3, p. 832-842

Research output: Contribution to journalArticleAcademicpeer-review

Widespread Disruption of Functional Brain Organization in Early-Onset Alzheimer's Disease

Adriaanse, S. M., Binnewijzend, M. A. A., Ossenkoppele, R., Tijms, B. M., van der Flier, W. M., Koene, T., Smits, L. L., Wink, A. M., Scheltens, P., van Berckel, B. N. M. & Barkhof, F., 2014, In : PLoS ONE. 9, 7, p. e102995 e102995.

Research output: Contribution to journalArticleAcademicpeer-review

2013

Accelerated aging, decreased white matter integrity, and associated neuropsychological dysfunction 25 years after pediatric lymphoid malignancies

Schuitema, I., Deprez, S., van Hecke, W., Daams, M., Uyttebroeck, A., Sunaert, S., Barkhof, F., van Dulmen-den Broeder, E., van der Pal, H. J., Bos, C., Veerman, A. J. & de Sonneville, L. M., 2013, In : Journal of Clinical Oncology. 31, 27, p. 3378-3388

Research output: Contribution to journalArticleAcademicpeer-review

Accurate white matter lesion segmentation by k nearest neighbor classification with tissue type priors (kNN-TTPs)

Steenwijk, M. D., Pouwels, P. J., Daams, M., van Dalen, J. W., Caan, M. W., Richard, E., Barkhof, F. & Vrenken, H., 2013, In : NeuroImage: Clinical. 3, p. 462-469

Research output: Contribution to journalArticleAcademicpeer-review

An MRI rating scale for amyloid-related imaging abnormalities with edema or effusion

Barkhof, F., Daams, M., Scheltens, P., Brashear, H. R., Arrighi, H. M., Bechten, A. K., Morris, K., McGovern, M. & Wattjes, M. P., 2013, In : American Journal of Neuroradiology. 34, 8, p. 1550-1555

Research output: Contribution to journalArticleAcademicpeer-review

Atypical idiopathic inflammatory demyelinating lesions: prognostic implications and relation to multiple sclerosis

Wallner-Blazek, M., Rovira, A., Fillipp, M., Rocca, M. A., Miller, D. H., Schmierer, K., Frederiksen, J., Gass, A., Gama, H., Tilbery, C. P., Da Rocha, A. J., Flores, J., Barkhof, F., Seewann, A., Palace, J., Yousry, T., Montalban, X., Enzinger, C. & Fazekas, F., 2013, In : Journal of Neurology. 260, 8, p. 2016-2022

Research output: Contribution to journalArticleAcademicpeer-review

Brain atrophy and lesion load predict long term disability in multiple sclerosis

Popescu, V., Agosta, F., Hulst, H. E., Sluimer, I. C., Knol, D. L., Sormani, M. P., Enzinger, C., Ropele, S., Alonso, J., Sastre-Garriga, J., Rovira, A., Montalban, X., Bodini, B., Ciccarelli, O., Khaleeli, Z., Chard, D. T., Matthews, L., Palace, J., Giorgio, A., De Stefano, N. & 9 others, Eisele, P., Gass, A., Polman, C. H., Uitdehaag, B. M. J., Messina, M. J., Comi, G., Filippi, M., Barkhof, F. & Vrenken, H., 2013, In : Journal of Neurology, Neurosurgery and Psychiatry. 84, 10, p. 1082-1091

Research output: Contribution to journalArticleAcademicpeer-review

Clinical application of multi-contrast 7-T MR imaging in multiple sclerosis: increased lesion detection compared to 3 T confined to grey matter

de Graaf, W. L., Kilsdonk, I. D., Lopez Soriano, A., Zwanenburg, J. J. M., Visser, F., Polman, C. H., Castelijns, J. A., Geurts, J. J. G., Pouwels, P. J. W., Luijten, P. R., Barkhof, F. & Wattjes, M. P., 2013, In : European Radiology. 23, 2, p. 528-540

Research output: Contribution to journalArticleAcademicpeer-review

Clinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis

Vennegoor, A., Rispens, T., Strijbis, E. M. M., Seewann, A., Uitdehaag, B. M. J., Balk, L. J., Barkhof, F., Polman, C. H., Wolbink, G. & Killestein, J., 2013, In : Multiple Sclerosis. 19, 5, p. 593-600

Research output: Contribution to journalArticleAcademicpeer-review

Cognitive and Clinical Dysfunction, Altered MEG Resting-State Networks and Thalamic Atrophy in Multiple Sclerosis

Tewarie, P. K., Schoonheim, M. M., Stam, C. J., van der Meer, M. L., van Dijk, B. W., Barkhof, F., Polman, C. H. & Hillebrand, A., 2013, In : PLoS ONE. 8, 7, p. e69318 e69318.

Research output: Contribution to journalArticleAcademicpeer-review

Cortical imaging in multiple sclerosis: recent findings and 'grand challenges'

Daams, M., Geurts, J. J. G. & Barkhof, F., 2013, In : Current Opinion in Neurology. 26, 4, p. 345-352

Research output: Contribution to journalArticleAcademicpeer-review

Different patterns of gray matter atrophy in early- and late-onset Alzheimer's disease

Möller, C., Vrenken, H., Jiskoot, L., Versteeg, A., Barkhof, F., Scheltens, P. & van der Flier, W. M., 2013, In : Neurobiology of Aging. 34, 8, p. 2014-2022

Research output: Contribution to journalArticleAcademicpeer-review

Diffusion changes predict cognitive and functional outcome: The LADIS study

Jokinen, H., Schmidt, R., Ropele, S., Fazekas, F., Gouw, A. A., Barkhof, F., Scheltens, P., Madureira, S., Verdelho, A., Ferro, J. M., Wallin, A., Poggesi, A., Inzitari, D., Pantoni, L. & Erkinjuntti, T., 2013, In : Annals of Neurology. 73, 5, p. 576-583

Research output: Contribution to journalArticleAcademicpeer-review

Efficient use of MRI for dose finding in multiple sclerosis

Barkhof, F., 2013, In : Lancet Neurology. 12, 8, p. 730-731

Research output: Contribution to journalArticleAcademicpeer-review

Fingolimod versus intramuscular interferon in patient subgroups from TRANSFORMS

Cohen, J. A., Barkhof, F., Comi, G., Izquierdo, G., Khatri, B., Montalban, X., Pelletier, J., Eckert, B., Haring, D. A. & Francis, G., 2013, In : Journal of Neurology. 260, 8, p. 2023-2032

Research output: Contribution to journalArticleAcademicpeer-review

Functional connectivity changes in multiple sclerosis patients: A graph analytical study of MEG resting state data

Schoonheim, M. M., Geurts, J. J. G., Landi, D., Douw, L., van der Meer, M. L., Vrenken, H., Polman, C. H., Barkhof, F. & Stam, C. J., 2013, In : Human Brain Mapping. 34, 1, p. 52-61

Research output: Contribution to journalArticleAcademicpeer-review

Functional segmentation of the hippocampus in the healthy human brain and in Alzheimer's disease

Zarei, M., Beckmann, C. F., Binnewijzend, M. A. A., Schoonheim, M. M., Oghabian, M. A., Sanz-Arigita, E. J., Scheltens, P., Matthews, P. M. & Barkhof, F., 2013, In : NeuroImage. 66, p. 28-35

Research output: Contribution to journalArticleAcademicpeer-review

Glutamate gene polymorphisms predict brain volumes in multiple sclerosis

Strijbis, E. M. M., Inkster, B., Vounou, M., Naegelin, Y., Kappos, L., Radue, E. W., Matthews, P. M., Uitdehaag, B. M. J., Barkhof, F., Polman, C. H., Montana, G. & Geurts, J. J. G., 2013, In : Multiple Sclerosis. 19, 3, p. 281-288

Research output: Contribution to journalArticleAcademicpeer-review

Histone deacetylase gene variants predict brain volume changes in multiple sclerosis

Inkster, B., Strijbis, E. M. M., Vounou, M., Kappos, L., Radue, E. W., Matthews, P. M., Uitdehaag, B. M. J., Barkhof, F., Polman, C. H., Montana, G. & Geurts, J. J. G., 2013, In : Neurobiology of Aging. 34, 1, p. 238-247

Research output: Contribution to journalArticleAcademicpeer-review

Imaging markers for Alzheimer disease: which vs how

Frisoni, G. B., Bocchetta, M., Chetelat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E., Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R. J., Jagust, W. J., Johnson, K. A., Rowe, C. C., Sperling, R. A. & 5 others, Thies, W., Wahlund, L. O., Weiner, M. W., Pasqualetti, P. & deCarli, C., 2013, In : Neurology. 81, 5, p. 487-500

Research output: Contribution to journalArticleAcademicpeer-review

Improvement of White Matter Changes on Neuroimaging Modalities After Stem Cell Transplant in Metachromatic Leukodystrophy

van Egmond, M. E., Pouwels, P. J. W., Boelens, J. J., Lindemans, C. A., Barkhof, F., Steenwijk, M. D., van Hasselt, P. M., van der Knaap, M. S. & Wolf, N. I., 2013, In : JAMA Neurology. 70, 6, p. 779-782

Research output: Contribution to journalArticleAcademicpeer-review

Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial

Dodel, R., Rominger, A., Bartenstein, P., Barkhof, F., Blennow, K., Forster, S., Winter, Y., Bach, J. P., Popp, J., Alferink, J., Wiltfang, J., Buerger, K., Otto, M., Antuono, P., Jacoby, M., Richter, R., Stevens, J., Melamed, I., Goldstein, J., Haag, S. & 3 others, Wietek, S., Farlow, M. & Jessen, F., 2013, In : Lancet Neurology. 12, 3, p. 233-243

Research output: Contribution to journalArticleAcademicpeer-review

Language Comprehension in Young People with Severe Cerebral Palsy in Relation to Language Tracts: A Diffusion Tensor Imaging Study

Harlaar, L., Pouwels, P. J., Geytenbeek, J. J. M., Oostrom, K. J., Barkhof, F. & Vermeulen, R. J., 2013, In : Neuropediatrics. 44, 5, p. 286-290

Research output: Contribution to journalArticleAcademicpeer-review

Location of brain lesions predicts conversion of clinically isolated syndromes to multiple sclerosis

Giorgio, A., Battaglini, M., Rocca, M. A., De Leucio, A., Absinta, M., van Schijndel, R. A., Rovira, A., Tintore, M., Chard, D., Ciccarelli, O., Enzinger, C., Gasperini, C., Frederiksen, J., Filippi, M., Barkhof, F. & De Stefano, N., 2013, In : Neurology. 80, 3, p. 234-241

Research output: Contribution to journalArticleAcademicpeer-review

Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

Clerx, L., van Rossum, I. A., Burns, L., Knol, D. L., Scheltens, P., Verhey, F., Aalten, P., Lapuerta, P., van de Pol, L. A., van Schijndel, R. A., Jong, R., Barkhof, F., Wolz, R., Rueckert, D., Bocchetta, M., Tsolaki, M., Nobili, F., Wahlund, L. O., Minthon, L., Frolich, L. & 3 others, Hampel, H., Soininen, H. & Visser, P. J., 2013, In : Neurobiology of Aging. 34, 8, p. 2003-2013

Research output: Contribution to journalArticleAcademicpeer-review

Microglial activation in Alzheimer's disease: an (R)-[C-11]PK11195 positron emission tomography study

Schuitemaker, A., Kropholler, M. A., Boellaard, R., van der Flier, W. M., Kloet, R. W., van der Doef, T. F., Knol, D. L., Windhorst, A. D., Luurtsema, G., Barkhof, F., Jonker, C., Lammertsma, A. A., Scheltens, P. & van Berckel, B. N. M., 2013, In : Neurobiology of Aging. 34, 1, p. 128-136

Research output: Contribution to journalArticleAcademicpeer-review