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Research Output 1993 2019

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2013

Clinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis

Vennegoor, A., Rispens, T., Strijbis, E. M. M., Seewann, A., Uitdehaag, B. M. J., Balk, L. J., Barkhof, F., Polman, C. H., Wolbink, G. & Killestein, J., 2013, In : Multiple Sclerosis. 19, 5, p. 593-600

Research output: Contribution to journalArticleAcademicpeer-review

Cognitive and Clinical Dysfunction, Altered MEG Resting-State Networks and Thalamic Atrophy in Multiple Sclerosis

Tewarie, P. K., Schoonheim, M. M., Stam, C. J., van der Meer, M. L., van Dijk, B. W., Barkhof, F., Polman, C. H. & Hillebrand, A., 2013, In : PLoS ONE. 8, 7, p. e69318 e69318.

Research output: Contribution to journalArticleAcademicpeer-review

Cortical imaging in multiple sclerosis: recent findings and 'grand challenges'

Daams, M., Geurts, J. J. G. & Barkhof, F., 2013, In : Current Opinion in Neurology. 26, 4, p. 345-352

Research output: Contribution to journalArticleAcademicpeer-review

Different patterns of gray matter atrophy in early- and late-onset Alzheimer's disease

Möller, C., Vrenken, H., Jiskoot, L., Versteeg, A., Barkhof, F., Scheltens, P. & van der Flier, W. M., 2013, In : Neurobiology of Aging. 34, 8, p. 2014-2022

Research output: Contribution to journalArticleAcademicpeer-review

Diffusion changes predict cognitive and functional outcome: The LADIS study

Jokinen, H., Schmidt, R., Ropele, S., Fazekas, F., Gouw, A. A., Barkhof, F., Scheltens, P., Madureira, S., Verdelho, A., Ferro, J. M., Wallin, A., Poggesi, A., Inzitari, D., Pantoni, L. & Erkinjuntti, T., 2013, In : Annals of Neurology. 73, 5, p. 576-583

Research output: Contribution to journalArticleAcademicpeer-review

Efficient use of MRI for dose finding in multiple sclerosis

Barkhof, F., 2013, In : Lancet Neurology. 12, 8, p. 730-731

Research output: Contribution to journalArticleAcademicpeer-review

Fingolimod versus intramuscular interferon in patient subgroups from TRANSFORMS

Cohen, J. A., Barkhof, F., Comi, G., Izquierdo, G., Khatri, B., Montalban, X., Pelletier, J., Eckert, B., Haring, D. A. & Francis, G., 2013, In : Journal of Neurology. 260, 8, p. 2023-2032

Research output: Contribution to journalArticleAcademicpeer-review

Functional connectivity changes in multiple sclerosis patients: A graph analytical study of MEG resting state data

Schoonheim, M. M., Geurts, J. J. G., Landi, D., Douw, L., van der Meer, M. L., Vrenken, H., Polman, C. H., Barkhof, F. & Stam, C. J., 2013, In : Human Brain Mapping. 34, 1, p. 52-61

Research output: Contribution to journalArticleAcademicpeer-review

Functional segmentation of the hippocampus in the healthy human brain and in Alzheimer's disease

Zarei, M., Beckmann, C. F., Binnewijzend, M. A. A., Schoonheim, M. M., Oghabian, M. A., Sanz-Arigita, E. J., Scheltens, P., Matthews, P. M. & Barkhof, F., 2013, In : NeuroImage. 66, p. 28-35

Research output: Contribution to journalArticleAcademicpeer-review

Glutamate gene polymorphisms predict brain volumes in multiple sclerosis

Strijbis, E. M. M., Inkster, B., Vounou, M., Naegelin, Y., Kappos, L., Radue, E. W., Matthews, P. M., Uitdehaag, B. M. J., Barkhof, F., Polman, C. H., Montana, G. & Geurts, J. J. G., 2013, In : Multiple Sclerosis. 19, 3, p. 281-288

Research output: Contribution to journalArticleAcademicpeer-review

Histone deacetylase gene variants predict brain volume changes in multiple sclerosis

Inkster, B., Strijbis, E. M. M., Vounou, M., Kappos, L., Radue, E. W., Matthews, P. M., Uitdehaag, B. M. J., Barkhof, F., Polman, C. H., Montana, G. & Geurts, J. J. G., 2013, In : Neurobiology of Aging. 34, 1, p. 238-247

Research output: Contribution to journalArticleAcademicpeer-review

Imaging markers for Alzheimer disease: which vs how

Frisoni, G. B., Bocchetta, M., Chetelat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E., Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R. J., Jagust, W. J., Johnson, K. A., Rowe, C. C., Sperling, R. A. & 5 othersThies, W., Wahlund, L. O., Weiner, M. W., Pasqualetti, P. & deCarli, C., 2013, In : Neurology. 81, 5, p. 487-500

Research output: Contribution to journalArticleAcademicpeer-review

Improvement of White Matter Changes on Neuroimaging Modalities After Stem Cell Transplant in Metachromatic Leukodystrophy

van Egmond, M. E., Pouwels, P. J. W., Boelens, J. J., Lindemans, C. A., Barkhof, F., Steenwijk, M. D., van Hasselt, P. M., van der Knaap, M. S. & Wolf, N. I., 2013, In : JAMA Neurology. 70, 6, p. 779-782

Research output: Contribution to journalArticleAcademicpeer-review

Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial

Dodel, R., Rominger, A., Bartenstein, P., Barkhof, F., Blennow, K., Forster, S., Winter, Y., Bach, J. P., Popp, J., Alferink, J., Wiltfang, J., Buerger, K., Otto, M., Antuono, P., Jacoby, M., Richter, R., Stevens, J., Melamed, I., Goldstein, J., Haag, S. & 3 othersWietek, S., Farlow, M. & Jessen, F., 2013, In : Lancet Neurology. 12, 3, p. 233-243

Research output: Contribution to journalArticleAcademicpeer-review

Language Comprehension in Young People with Severe Cerebral Palsy in Relation to Language Tracts: A Diffusion Tensor Imaging Study

Harlaar, L., Pouwels, P. J., Geytenbeek, J. J. M., Oostrom, K. J., Barkhof, F. & Vermeulen, R. J., 2013, In : Neuropediatrics. 44, 5, p. 286-290

Research output: Contribution to journalArticleAcademicpeer-review

Location of brain lesions predicts conversion of clinically isolated syndromes to multiple sclerosis

Giorgio, A., Battaglini, M., Rocca, M. A., De Leucio, A., Absinta, M., van Schijndel, R. A., Rovira, A., Tintore, M., Chard, D., Ciccarelli, O., Enzinger, C., Gasperini, C., Frederiksen, J., Filippi, M., Barkhof, F. & De Stefano, N., 2013, In : Neurology. 80, 3, p. 234-241

Research output: Contribution to journalArticleAcademicpeer-review

Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

Clerx, L., van Rossum, I. A., Burns, L., Knol, D. L., Scheltens, P., Verhey, F., Aalten, P., Lapuerta, P., van de Pol, L. A., van Schijndel, R. A., Jong, R., Barkhof, F., Wolz, R., Rueckert, D., Bocchetta, M., Tsolaki, M., Nobili, F., Wahlund, L. O., Minthon, L., Frolich, L. & 3 othersHampel, H., Soininen, H. & Visser, P. J., 2013, In : Neurobiology of Aging. 34, 8, p. 2003-2013

Research output: Contribution to journalArticleAcademicpeer-review

Microglial activation in Alzheimer's disease: an (R)-[C-11]PK11195 positron emission tomography study

Schuitemaker, A., Kropholler, M. A., Boellaard, R., van der Flier, W. M., Kloet, R. W., van der Doef, T. F., Knol, D. L., Windhorst, A. D., Luurtsema, G., Barkhof, F., Jonker, C., Lammertsma, A. A., Scheltens, P. & van Berckel, B. N. M., 2013, In : Neurobiology of Aging. 34, 1, p. 128-136

Research output: Contribution to journalArticleAcademicpeer-review

Multicontrast MR imaging at 7T in multiple sclerosis: highest lesion detection in cortical gray matter with 3D-FLAIR

Kilsdonk, I. D., de Graaf, W. L., Lopez Soriano, A., Zwanenburg, J. J., Visser, F., Kuijer, J. P. A., Geurts, J. J. G., Pouwels, P. J. W., Polman, C. H., Castelijns, J. A., Luijten, P. R., Barkhof, F. & Wattjes, M. P., 2013, In : American Journal of Neuroradiology. 34, 4, p. 791-796

Research output: Contribution to journalArticleAcademicpeer-review

Multiple sclerosis: CCSVI deconstructed and discarded

Barkhof, F. & Wattjes, M. P., 2013, In : Nature Reviews Neurology. 9, p. 661-662

Research output: Contribution to journalArticleAcademicpeer-review

Mystery Case: Balo concentric sclerosis

Grooters, G. S., Visser, L. H., Barkhof, F., van der Knaap, M. S. & van Asseldonk, J. T., 2013, In : Neurology. 80, 7, p. E71-E72

Research output: Contribution to journalArticleAcademicpeer-review

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

Wardlaw, J. M., Smith, E. E., Biessels, G. J., Cordonnier, C., Fazekas, F., Frayne, R., Lindley, R. I., O'Brien, J. T., Barkhof, F., Benavente, O. R., Black, S. E., Brayne, C., Breteler, M., Chabriat, H., deCarli, C., de Leeuw, F. E., Doubal, F., Duering, M., Fox, N. C., Greenberg, S. & 16 othersHachinski, V., Kilimann, I., Mok, V., van Oostenbrugge, R., Pantoni, L., Speck, O., Stephan, B. C. M., Teipel, S., Viswanathan, A., Werring, D., Chen, C., Smith, C., van Buchem, M., Norrving, B., Gorelick, P. B. & Dichgans, M., 2013, In : Lancet Neurology. 12, 8, p. 822-838

Research output: Contribution to journalArticleAcademicpeer-review

PML in a Patient Treated with Dimethyl Fumarate from a Compounding Pharmacy

van Oosten, B. W., Killestein, J., Barkhof, F., Polman, C. H. & Wattjes, M. P., 2013, In : New England Journal of Medicine. 368, 17, p. 1658-1659

Research output: Contribution to journalArticleAcademicpeer-review

Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease

Prestia, A., Caroli, A., van der Flier, W. M., Ossenkoppele, R., van Berckel, B. N. M., Barkhof, F., Teunissen, C. E., Wall, A. E., Carter, S. F., Scholl, M., Choo, I. H., Nordberg, A., Scheltens, P. & Frisoni, G. B., 2013, In : Neurology. 80, 11, p. 1048-1056

Research output: Contribution to journalArticleAcademicpeer-review

Predictors of Progression from Mild Cognitive Impairment to Dementia in the Placebo-Arm of a Clinical Trial Population

Prins, N. D., van der Flier, W. M., Brashear, H. R., Knol, D. L., van de Pol, L. A., Barkhof, F. & Scheltens, P., 2013, In : Journal of Alzheimer's Disease. 36, 1, p. 79-85

Research output: Contribution to journalArticleAcademicpeer-review

Recommendations to improve imaging and analysis of brain lesion load and atrophy in longitudinal studies of multiple sclerosis

Vrenken, H., Jenkinson, M., Horsfield, M. A., Battaglini, M., van Schijndel, R. A., Rostrup, E., Geurts, J. J. G., Fisher, E., Zijdenbos, A., Ashburner, J., Miller, D. H., Filippi, M., Fazekas, F., Rovaris, M., Rovira, A., Barkhof, F. & De Stefano, N., 2013, In : Journal of Neurology. 260, 10, p. 2458-2471

Research output: Contribution to journalArticleAcademicpeer-review

Relationships Between White Matter Hyperintensities, Cerebral Amyloid Angiopathy and Dementia in a Population-based Sample of the Oldest Old

Tanskanen, M., Kalaria, R. N., Notkola, I. L., Makela, M., Polvikoski, T., Myllykangas, L., Sulkava, R., Kalimo, H., Paetau, A., Scheltens, P., Barkhof, F., van Straaten, E. C. W. & Erkinjuntti, T., 2013, In : Current Alzheimer Research. 10, 10, p. 1090-1097

Research output: Contribution to journalArticleAcademicpeer-review

Relevance of Spinal Cord Abnormalities to Clinical Disability in Multiple Sclerosis: MR Imaging Findings in a Large Cohort of Patients

Lukas, C., Sombekke, M. H., Bellenberg, B., Hahn, H. K., Popescu, V., Bendfeldt, K., Radue, E. W., Gass, A., Borgwardt, S. J., Kappos, L., Naegelin, Y., Knol, D. L., Polman, C. H., Geurts, J. J. G., Barkhof, F. & Vrenken, H., 2013, In : Radiology. 269, 2, p. 541-551

Research output: Contribution to journalArticleAcademicpeer-review

Resection Probability Maps for Quality Assessment of Glioma Surgery without Brain Location Bias

Versélewel de Witt Hamer, P. C., Hendriks, E. J., Mandonnet, E., Barkhof, F., Zwinderman, A. H. & Duffau, H., 2013, In : PLoS ONE. 8, 9, e73353.

Research output: Contribution to journalArticleAcademicpeer-review

Single-Subject Grey Matter Graphs in Alzheimer's Disease

Tijms, B. M., Moller, C., Vrenken, H., Wink, A. M., de Haan, W., van der Flier, W. M., Stam, C. J., Scheltens, P. & Barkhof, F., 2013, In : PLoS ONE. 8, 3, p. e58921 e58921.

Research output: Contribution to journalArticleAcademicpeer-review

Specific risk factors for microbleeds and white matter hyperintensities in Alzheimer's disease

Benedictus, M. R., Goos, J. D. C., Binnewijzend, M. A. A., Muller, M., Barkhof, F., Scheltens, P., Prins, N. D. & van der Flier, W. M., 2013, In : Neurobiology of Aging. 34, 11, p. 2488-2494

Research output: Contribution to journalArticleAcademicpeer-review

Spinal cord lesions in patients with clinically isolated syndrome A powerful tool in diagnosis and prognosis

Sombekke, M. H., Wattjes, M. P., Balk, L. J., Nielsen, J. M., Vrenken, H., Uitdehaag, B. M. J., Polman, C. H. & Barkhof, F., 2013, In : Neurology. 80, 1, p. 69-75

Research output: Contribution to journalArticleAcademicpeer-review

The chameleon of neuroinflammation: magnetic resonance imaging characteristics of natalizumab-associated progressive multifocal leukoencephalopathy

Wattjes, M. P., Richert, N. D., Killestein, J., de Vos, M. L., Sanchez, E., Snæbjörnsson, P., Cadavid, D. & Barkhof, F., 2013, In : Multiple Sclerosis. 19, 14, p. 1826-1840

Research output: Contribution to journalArticleAcademicpeer-review

Visual ratings of atrophy in MCI: prediction of conversion and relationship with CSF biomarkers

Lehmann, M., Koedam, E. L., Barnes, J., Bartlett, J. W., Barkhof, F., Wattjes, M. P., Schott, J. M., Scheltens, P. & Fox, N. C., 2013, In : Neurobiology of Aging. 34, 1, p. 73-82

Research output: Contribution to journalArticleAcademicpeer-review

2012

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

Coles, A. J., Twyman, C. L., Arnold, D. L., Cohen, J. A., Confavreux, C., Fox, E. J., Hartung, H. P., Havrdova, E., Selmaj, K. W., Weiner, H. L., Miller, T., Fisher, E., Sandbrink, R., Lake, S. L., Margolin, D. H., Oyuela, P., Barkhof, F., Panzara, M. A. & Compston, D., 2012, In : Lancet. 380, 9856, p. 1829-1839

Research output: Contribution to journalArticleAcademicpeer-review

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

Cohen, J. A., Coles, A. J., Arnold, D. L., Confavreux, C., Fox, E. J., Hartung, H. P., Havrdova, E., Selmaj, K. W., Weiner, H. L., Fisher, E., Brinar, V. V., Giovannoni, G., Stojanovic, M., Ertik, B. I., Lake, S. L., Margolin, D. H., Barkhof, F., Panzara, M. A. & Compston, D., 2012, In : Lancet. 380, 9856, p. 1819-1828

Research output: Contribution to journalArticleAcademicpeer-review

Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement

Ossenkoppele, R., Zwan, M. D., Tolboom, N., van Assema, D. M. E., Adriaanse, S. F., Kloet, R. W., Boellaard, R., Windhorst, A. D., Barkhof, F., Lammertsma, A. A., Scheltens, P., van der Flier, W. M. & van Berckel, B. N. M., 2012, In : Brain. 135, p. 2115-2125

Research output: Contribution to journalArticleAcademicpeer-review

42 Downloads (Pure)

A Randomized Trial of High-Dose Vitamin D2 in Relapsing-remitting Multiple Sclerosis

Leitner, H. H., Grimaldi, L., Barkhof, F., Beelke, M., Burton, H., Holmoy, T., Hupperts, R., Killestein, J., Rieckmann, P., Schluep, M. & Smolders, J., 2012, In : Neurology. 78, 11, p. 840-841

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Association between pathological and MRI findings in multiple sclerosis

Filippi, M. D., Rocca, M. A., Barkhof, F., Bruck, W., Chen, J. T., Comi, G., DeLuca, G., De Stefano, N., Erickson, B. J., Evangelou, N., Fazekas, F., Geurts, J. J. G., Lucchinetti, C., Miller, D. H., Pelletier, D., Popescu, B. F. G. & Lassmann, H., 2012, In : Lancet Neurology. 11, 4, p. 349-360

Research output: Contribution to journalArticleAcademicpeer-review

65 Downloads (Pure)

Brain atrophy accelerates cognitive decline in cerebral small vessel disease: The LADIS study

Jokinen, H., Lipsanen, J., Schmidt, R., Fazekas, F., Gouw, A. A., van der Flier, W. M., Barkhof, F., Madureira, S., Verdelho, A., Ferro, J. M., Wallin, A., Pantoni, L., Inzitari, D. & Erkinjuntti, T., 2012, In : Neurology. 78, 22, p. 1785-1792

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Callosal tissue loss parallels subtle decline in psychomotor speed. A longitudinal quantitative MRI study. The LADIS Study

Jokinen, H., Frederiksen, K. S., Garde, E., Skimminge, A., Siebner, H., Waldemar, G., Ylikoski, R., Madureira, S., Verdelho, A., van Straaten, E. C. W., Barkhof, F., Fazekas, F., Schmidt, R., Pantoni, L., Inzitari, D. & Erkinjuntti, T., 2012, In : Neuropsychologia. 50, 7, p. 1650-1655

Research output: Contribution to journalArticleAcademicpeer-review

Characteristics of Early MRI in Children and Adolescents with Vanishing White Matter

van der Lei, H. D. W., Steenweg, M. E., Barkhof, F., de Grauw, T., D'Hooghe, M., Morton, R., Shah, S., Wolf, N. & van der Knaap, M. S., 2012, In : Neuropediatrics. 43, 1, p. 22-26

Research output: Contribution to journalArticleAcademicpeer-review

Coil-treated Aneurysms: Decision Making Regarding Additional Treatment Based on Findings of MR Angiography and Intraarterial DSA

Schaafsma, J. D., Velthuis, B. K., van den Berg, R., Brouwer, P. A., Majoie, C. B. L. M., Barkhof, F., Eshghi, O., de Kort, G. A. P., Lo, R. T. H., Sprengers, M. E. S., van Rooij, W. J., Bot, J. C. J. & Rinkel, G. J. E., 2012, In : Radiology. 265, 3, p. 858-863

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of two dosing frequencies of subcutaneous interferon beta-1a in patients with a first clinical demyelinating event suggestive of multiple sclerosis (REFLEX): a phase 3 randomised controlled trial

Comi, G., De Stefano, N., Freedman, M. S., Barkhof, F., Polman, C. H., Uitdehaag, B. M. J., Casset-Semanaz, F., Hennessy, B., Moraga, M. S., Rocak, S., Stubinski, B. & Kappos, L., 2012, In : Lancet Neurology. 11, 1, p. 33-41

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic relevance of high field MRI in clinical neuroradiology: the advantages and challenges of driving a sports car

Wattjes, M. P. & Barkhof, F., 2012, In : European Radiology. 22, 11, p. 2304-2306

Research output: Contribution to journalArticleAcademicpeer-review

Diffusion tensor imaging in type 1 diabetes: decreased white matter integrity relates to cognitive functions

van Duinkerken, E., Schoonheim, M. M., IJzerman, R. G., Klein, M., Ryan, C. M., Moll, A. C., Snoek, F. J., Barkhof, F., Diamant, M. & Pouwels, P. J. W., 2012, In : Diabetologia. 55, 4, p. 1218-1220

Research output: Contribution to journalArticleAcademicpeer-review