Projects per year
Personal profile
Research interests
In our Onco-Pathology research group, we perform genomic profiling of solid tumours to identify clinically relevant subgroups of patients for (future) personalised therapy. We focus on the cancers with the worst prognosis: the Hepato-Pancreato-Biliary and Ovarian adenocarcinomas.
For genomic profiling and other scientific research, the use of high quality biospecimens with pathoclinical details is essential. Facilitation of the responsible use of human tissue for scientific research is the main aim of the research infrastructure Pathology Biobanking and Research (riPBR), of which I am the coordinator.
Network
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Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits
Rodriguez, E., Boelaars, K., Brown, K., Madunić, K., van Ee, T., Dijk, F., Verheij, J., Li, R. J. E., Schetters, S. T. T., Meijer, L. L., le Large, T. Y. S., Driehuis, E., Clevers, H., Bruijns, S. C. M., O’Toole, T., van Vliet, S. J., Bijlsma, M. F., Wuhrer, M., Kazemier, G., Giovannetti, E., & 2 others , 1 Dec 2022, In: Communications Biology. 5, 1, 41.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
A Paradoxical Role for Regulatory T Cells in the Tumor Microenvironment of Pancreatic Cancer
Brouwer, T., Ijsselsteijn, M., Oosting, J., Ruano, D., van der Ploeg, M., Dijk, F., Bonsing, B., Fariña, A., Morreau, H., Vahrmeijer, A. & Miranda, N. D., 1 Aug 2022, In: Cancers. 14, 16, 3862.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Circulating tumor DNA predicts outcome in metastatic gastroesophageal cancer
van Velzen, M. J. M., Creemers, A., van den Ende, T., Schokker, S., Krausz, S., Reinten, R. J., Dijk, F., van Noesel, C. J. M., Halfwerk, H., Meijer, S. L., Mearadji, B., Derks, S., Bijlsma, M. F. & van Laarhoven, H. W. M., Sep 2022, In: Gastric Cancer. 25, 5, p. 906-915 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Impact of classical and basal-like molecular subtypes on overall survival in resected pancreatic cancer in the SPACIOUS-2 multicentre study
Dutch Pancreatic Cancer Group, 14 Oct 2022, In: The British journal of surgery. 109, 11, p. 1150-1155 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Bayesian log-normal deconvolution for enhanced in silico microdissection of bulk gene expression data
Andrade Barbosa, B. R., van Asten, S. D., Oh, J. W., Farina-Sarasqueta, A., Verheij, J., Dijk, F., van Laarhoven, H. W. M., Ylstra, B., Garcia Vallejo, J. J., van de Wiel, M. A. & Kim, Y., Dec 2021, In: Nature Communications. 12, 1, 6106.Research output: Contribution to journal › Article › Academic › peer-review
Open Access